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Updated 26 Aug 2026 · ClinicalTrials.gov

Clinical Trials in Birmingham

← All UK trials

The most recently updated industry-sponsored clinical trials recruiting across the United Kingdom — searchable by condition, sponsor, phase and city. Refreshed daily from the ClinicalTrials.gov registry.

25
Recruiting now
32
Studies tracked
Birmingham
Selected city
Active Phase 3
A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
Hidradenitis Suppurativa (HS)
Incyte Corporation · started 2024-01-30
📍 Birmingham · Dudley · Salford
NCT06212999 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer
Mirati Therapeutics Inc. · started 2020-12-02
📍 Birmingham · Edinburgh · Kent · Leicester · London
NCT04613596 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Pancreatic Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma (PDAC)
Revolution Medicines, Inc. · started 2025-12-15
📍 Birmingham · Glasgow · London · Manchester
NCT07252232 on ClinicalTrials.gov ↗
By invitation
Recovery and Early Sleep Tracking Using the SuperPatch REM Patch
Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Shift Work Sleep Disorders
SuperPatch Limited LLC · started 2026-05-15
📍 Birmingham
NCT07785960 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Chronic Graft-versus-host-disease
Incyte Corporation · started 2026-05-20
📍 Birmingham · Cambridge · Glasgow · Leeds · London
NCT07124078 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
Primary Biliary Cholangitis, PBC
Mirum Pharmaceuticals, Inc. · started 2021-09-22
📍 Southampton · Birmingham · Belfast · London · Newcastle upon Tyne
NCT05050136 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
Unresectable Hepatocellular Carcinoma
Hoffmann-La Roche · started 2021-04-26
📍 Birmingham · Liverpool · London · Manchester · Newcastle upon Tyne
NCT04770896 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Diabetes Mellitus, Type 1
Eli Lilly and Company · started 2026-01-12
📍 Birmingham · Cambridge · Cardiff · Glasgow · London
NCT07222137 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2)
Chronic Hepatitis D Infection
Mirum Pharmaceuticals, Inc. · started 2025-08-27
📍 Birmingham · London · Manchester · Cottingham
NCT07200908 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Metastatic Castration-resistant Prostatic Neoplasms
Janssen Research & Development, LLC · started 2025-09-02
📍 Birmingham · London · Manchester · Sutton
NCT07164443 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Graves' Disease
Immunovant Sciences GmbH · started 2024-12-17
📍 Birmingham · Bristol · Coventry · London · Cambridge
NCT06727604 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
Malignant Neoplasm
Merck Sharp & Dohme LLC · started 2025-08-11
📍 East Sussex · Truro · London · Edinburgh · Birmingham
NCT06979596 on ClinicalTrials.gov ↗
Recruiting Phase 2
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
Lupus Nephritis
Autolus Limited · started 2026-01-16
📍 Birmingham · Bristol · Cambridge · Edinburgh · Glasgow
NCT07053800 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
Cardiovascular Disease
AstraZeneca · started 2025-06-04
📍 Birmingham · Bournemouth · Bridgend · Bristol · Calow
NCT07000357 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs
Acromegaly
Debiopharm International SA · started 2025-11-26
📍 Birmingham · Leeds
NCT06930625 on ClinicalTrials.gov ↗
Active Phase 3
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
Eli Lilly and Company · started 2024-04-30
📍 Aberdeen · Birmingham · Bromborough · Coventry · Glasgow
NCT06383390 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
Myelofibrosis, Anemia
Takeda · started 2026-09-02
📍 Lincoln · Leicester · London · Sunderland · Birmingham
NCT07623161 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
Merck Sharp & Dohme LLC · started 2025-04-09
📍 Cambridge · Edinburgh · Preston · London · Sutton
NCT06824467 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
CLL, Chronic Lymphocytic Leukemia
BeOne Medicines · started 2025-04-10
📍 Aberdeen · Birmingham · Bournemouth · London · Southampton
NCT06846671 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Atherosclerosis Cardiovascular Disease, Chronic Kidney Disease
Eli Lilly and Company · started 2025-12-01
📍 Birmingham · Blackpool · Bromborough · Newcastle · Newquay
NCT07241390 on ClinicalTrials.gov ↗
Recruiting Phase 3
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
Multiple Myeloma
Pfizer · started 2024-02-08
📍 Milton Keynes · Bodelwyddan · Bournemouth · Poole · Eastbourne
NCT06152575 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Carcinoma, Non-Small-Cell Lung
Eli Lilly and Company · started 2025-03-27
📍 Birmingham · East Sussex · Huddersfield · London · Manchester
NCT06890598 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Type 2 Diabetes
Eli Lilly and Company · started 2025-03-28
📍 Birmingham · Blackpool · Bristol · Bromborough · Newcastle
NCT06897475 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Non-Small Cell Lung Cancer (NSCLC)
Amgen · started 2023-11-16
📍 Birmingham · Inverness · London · Northwood · Nottingham
NCT05920356 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Colon Adenocarcinoma, Rectal Adenocarcinoma
Merck Sharp & Dohme LLC · started 2025-07-16
📍 Birmingham · London · Oxford · Coventry · Cardiff
NCT06997497 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Prostate Cancer, Prostatic Neoplasms
Merck Sharp & Dohme LLC · started 2025-05-13
📍 Cambridge · London · Exeter · Birmingham · Northwood
NCT06925737 on ClinicalTrials.gov ↗
Active Phase 3
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Tuberous Sclerosis Complex
Novartis Pharmaceuticals · started 2017-08-23
📍 Birmingham · Buckinghamshire · Cambridge · Liverpool · London
NCT02962414 on ClinicalTrials.gov ↗
Active
CGM Use in Adults With Type 2 Diabetes on Basal Insulin
Diabetes Mellitus, Type 2
Abbott Diabetes Care · started 2023-07-14
📍 Ashton-under-Lyne · Bath · Birmingham · Cambridge · Darlington
NCT05944432 on ClinicalTrials.gov ↗
Recruiting Phase 3
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Kidney Disease, Chronic
Boehringer Ingelheim · started 2024-08-30
📍 Antrim · Basildon · Belfast · Birmingham · Blackburn
NCT06531824 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Myelodysplastic Syndromes
Takeda · started 2025-05-06
📍 Aberdeen · Rhyl · Leicester · High Heaton · Sunderland
NCT06499285 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC · started 2025-10-08
📍 Truro · London · Birmingham · Leicester
NCT07190248 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Metastatic Colorectal Cancer
Amgen · started 2024-07-17
📍 Birmingham · Glasgow · London · Maidstone · Northwood
NCT06252649 on ClinicalTrials.gov ↗
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Chronic Lymphocytic Leukemia · 5 Prostate Cancer · 4 Breast Cancer · 3 Non-small Cell Lung Cancer · 3 Healthy · 3 Ulcerative Colitis · 3 Crohn's Disease · 3 Advanced Solid Tumor · 3 Multiple Myeloma · 3 Neoplasm Metastasis · 3 Heart Failure · 3 Hypertension · 2 Metastatic Colorectal Cancer · 2 Obesity or Overweight · 2 Diabetes Mellitus, Type 2 · 2 Graves' Disease · 2
Cite this page

Priya Life Science (2026). Clinical Trials in the UK Tracker. Available at: https://priyalifescience.com/clinical-trials-uk/city/birmingham (Accessed: 26 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one UK site, most recently updated first, refreshed daily. This is a curated slice of the registry, not every UK trial; UK studies may also be registered on ISRCTN. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our UK Pharma Salary Guide, or see our Ireland, EU and USA trackers.