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Compound · clinical trials

Velcade clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 17 trials in our Italy, Germany, France, Canada, Spain, Australia, Israel, USA, Japan, Denmark, Poland, Turkey, UK, Netherlands, China, Belgium, Czechia, Norway, Sweden, Brazil, Mexico, South Korea, Taiwan, India, Austria, Portugal and Switzerland registers that name Velcade as an intervention. Synced 27 Sep 2026
17Current trials
6Recruiting now
16Lead sponsors
27Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Velcade is named as an intervention in 17 current clinical trials in our Italy, Germany, France, Canada, Spain, Australia, Israel, USA, Japan, Denmark, Poland, Turkey, UK, Netherlands, China, Belgium, Czechia, Norway, Sweden, Brazil, Mexico, South Korea, Taiwan, India, Austria, Portugal and Switzerland registers. 6 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Stichting European Myeloma Network (2). The most-studied condition is Multiple Myeloma. The EU clinical trials register (CTIS) separately lists 3 authorised or ongoing trials.

Trials by status

  • Recruiting635%
  • Not yet open16%
  • Active, closed1059%

Trials by phase

  • Phase 3741%
  • Phase 2529%
  • Phase 1/2318%
  • Phase 2/316%
  • Phase 416%
01

Clinical trials of Velcade

17 trials
StudyPhaseStatusLead sponsorRegisters
Elranatamab/Lenalidomide Consolidation and/or Elranatamab Maintenance Versus Standard of Care After D-VRd Induction in Transplant-eligible NDMM Patients
NCT06918002 · ClinicalTrials.gov ↗ · Multiple Myeloma, Newly Diagnosed
Phase 3 Recruiting Intergroupe Francophone du Myelome France
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)
NCT07391657 · ClinicalTrials.gov ↗ · Relapsed Refractory Multiple Myeloma
Phase 3 Recruiting AstraZeneca UK, USA, China, Germany, France, Spain, Italy, Poland, Norway, Canada, Brazil, Japan, South Korea, Taiwan, Australia
Expression-linked and R-ISS-adapted Stratification for First Line Therapy in Multiple Myeloma Patients
NCT05665140 · ClinicalTrials.gov ↗ · Newly Diagnosed Multiple Myeloma
Phase 2/3 Recruiting University Hopsital Schleswig Holstein Campus Lรผbeck Germany
A Multicentre, Non-Blinded Study Exploring Self-Administration of Chemotherapy in the Home Environment
NCT04268199 · ClinicalTrials.gov ↗ · Myeloma, Myeloma Multiple
Phase 2 Recruiting AHS Cancer Control Alberta Canada
A Study of Selinexor (Seli) + Low-dose Dexamethasone (LDD) in Penta-refractory Multiple Myeloma (MM), Seli and Bortezomib + LDD in Triple-class Refractory MM.
NCT04414475 · ClinicalTrials.gov ↗ · Multiple Myeloma, Refractory
Phase 2 Recruiting Karyopharm Therapeutics Inc Israel
Study of Iberdomide, Bortezomib, Dexamethasone With Isatuximab Added on Demand for ND-NTE MM Patients
NCT05272826 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 2 Recruiting Canadian Myeloma Research Group Canada
Isatuximab, Iberdomide, Bortezomib, Dexamethasone in Transplant Ineligible/Deferred Newly Diagnosed Myeloma
NCT07601100 · ClinicalTrials.gov ↗ · Newly Diagnosed Multiple Myeloma
Phase 1/2 Not yet open Dana-Farber Cancer Institute Israel
STUDY COMPARING TWO STANDARD TREATMENTS IN AUTOLOGOUS STEM CELL TRANSPLANTATION INELIGIBLE POPULATION AFFECTED BY MULTIPLE MYELOMA
NCT03829371 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 4 Active, closed University of Turin, Italy Italy
Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65
NCT01208662 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 3 Active, closed Paul Richardson, MD Israel
A Study to Investigate the Clinical Benefit of Isatuximab in Combination With Bortezomib, Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
NCT03319667 · Plasma Cell Myeloma
Phase 3 Active, closed Sanofi USA, China, Germany, France, Spain, Italy, Belgium, Sweden, Denmark, Poland, Czechia, Portugal, Turkey, Mexico, Japan, Taiwan, Australia
Trial on the Effect of Isatuximab to Lenalidomide/Bortezomib/Dexamethasone (RVd) Induction and Lenalidomide Maintenance in Patients With Newly Diagnosed Myeloma (GMMG HD7)
NCT03617731 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 3 Active, closed University of Heidelberg Medical Center Germany
Daratumumab, VELCADE (Bortezomib), Lenalidomide and Dexamethasone Compared to VELCADE, Lenalidomide and Dexamethasone in Subjects With Previously Untreated Multiple Myeloma
NCT03710603 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 3 Active, closed Stichting European Myeloma Network France, Spain, Italy, Netherlands, Belgium, Denmark, Poland, Switzerland, Czechia, Norway, Turkey, Australia
A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
NCT06208150 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 3 Active, closed Janssen Research & Development, LLC UK, USA, India, China, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Denmark, Poland, Austria, Czechia, Turkey, Canada, Brazil, Mexico, Japan, South Korea, Australia, Israel
Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease
NCT04166565 · ClinicalTrials.gov ↗ · Multiple Myeloma, Extramedullary Plasmacytoma
Phase 2 Active, closed Stichting European Myeloma Network Italy, Turkey
Selinexor With Alternating Bortezomib or Lenalidomide Plus Dexamethasone in TIE Newly Diagnosed MM Patients
NCT04717700 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 2 Active, closed Ida Bruun Kristensen Denmark, Norway
Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I
NCT02553460 · ClinicalTrials.gov ↗ · Acute Lymphoblastic Leukemia
Phase 1/2 Active, closed St. Jude Children's Research Hospital Canada
A Study to Determine Dose, Safety, Tolerability and Efficacy of CC-220 Monotherapy, and in Combination With Other Treatments in Subjects With Multiple Myeloma
NCT02773030 · Multiple Myeloma
Phase 1/2 Active, closed Celgene UK, USA, Germany, France, Spain, Italy, Netherlands, Canada, Japan, Australia, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Velcade in the EU trials register (CTIS)

3 trials

Authorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Velcade. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.

StudyPhaseStatusSponsorCountries
A Phase 3 Randomized Study Comparing Ramantamig Plus Daratumumab Versus Investigatorโ€™s Choice of Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) or Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy.
2026-526654-14-01 · Neoplasms
Phase 3 Authorised Janssen Cilag International Greece, Portugal, Italy + 6 more
A Phase 2, open-label, randomized, dose optimization study evaluating the efficacy and safety of belantamab mafodotin administered in combination with cyclophosphamide, bortezomib, and dexamethasone in adult participants with newly diagnosed amyloid light chain amyloidosis (ALANIS)
2025-522803-60-00 · Immune System Diseases
Phase 2 Authorised Glaxosmithkline Research & Development Limited Italy, Greece, Spain
An Open-label, Randomized Phase 3 Study of Linvoseltamab Monotherapy and Linvoseltamab plus Carfilzomib versus Standard of Care Combination Regimens in Patients with Relapsed/Refractory Multiple Myeloma
2024-519504-27-00 · CTIS ↗ · Neoplasms
Phase 3 Authorised Regeneron Pharmaceuticals Inc Greece, Spain, Poland + 7 more
03

Conditions studied with Velcade

10 conditions
Multiple Myeloma9Newly Diagnosed Multiple Myeloma2Relapsed Refractory Multiple Myeloma1Plasma Cell Myeloma1Multiple Myeloma, Newly Diagnosed1Extramedullary Plasmacytoma1Myeloma1Myeloma Multiple1Acute Lymphoblastic Leukemia1Multiple Myeloma, Refractory1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
Stichting European Myeloma Network2
Celgene1
Janssen Research & Development, LLC1
AstraZeneca1
Sanofi1
University of Heidelberg Medical Center1
University Hopsital Schleswig Holstein Campus Lรผbeck1
Intergroupe Francophone du Myelome1
University of Turin, Italy1
Ida Bruun Kristensen1
Canadian Myeloma Research Group1
AHS Cancer Control Alberta1
St. Jude Children's Research Hospital1
Karyopharm Therapeutics Inc1
Paul Richardson, MD1

+ 1 more sponsors in the trial list above.

05

By country register

RegisterTrialsRecruiting
Clinical trials in Italy71
Clinical trials in Germany62
Clinical trials in France62
Clinical trials in Canada63
Clinical trials in Spain51
Clinical trials in Australia51
Clinical trials in Israel51
Clinical trials in USA41
Clinical trials in Japan41
Clinical trials in Denmark40
Clinical trials in Poland41
Clinical trials in Turkey40
Clinical trials in UK31
Clinical trials in Netherlands30
Clinical trials in China31
Clinical trials in Belgium30
Clinical trials in Czechia30
Clinical trials in Norway31
Clinical trials in Sweden20
Clinical trials in Brazil21
Clinical trials in Mexico20
Clinical trials in South Korea21
Clinical trials in Taiwan21
Clinical trials in India10
Clinical trials in Austria10
Clinical trials in Portugal10
Clinical trials in Switzerland10
EU register (CTIS)3—

A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.

06

Related compounds

07

Questions about Velcade trials

How many clinical trials are testing Velcade?

17 current trials in our Italy, Germany, France, Canada, Spain, Australia, Israel, USA, Japan, Denmark, Poland, Turkey, UK, Netherlands, China, Belgium, Czechia, Norway, Sweden, Brazil, Mexico, South Korea, Taiwan, India, Austria, Portugal and Switzerland registers name Velcade as a drug or biological intervention, as of the registry sync on 27 September 2026. Completed and withdrawn studies are not counted.

Are Velcade trials recruiting patients?

Yes. 6 of the 17 trials are recruiting: 1 with sites in Italy, 2 with sites in Germany, 2 with sites in France, 3 with sites in Canada, 1 with sites in Spain, 1 with sites in Australia, 1 with sites in Israel, 1 with sites in USA, 1 with sites in Japan, 1 with sites in Poland, 1 with sites in UK, 1 with sites in China, 1 with sites in Norway, 1 with sites in Brazil, 1 with sites in South Korea and 1 with sites in Taiwan. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Velcade clinical trials?

Stichting European Myeloma Network (2), Celgene (1), Janssen Research & Development, LLC (1) and AstraZeneca (1), among 16 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Velcade works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Velcade works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Velcade (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 27 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.