EU Medicine Shortages Tracker 2026 - Live EMA Supply Shortage List

Shortage ongoing Parasitic Diseases · Protozoan Infections · Helminthiasis Reported 09/09/2026

Eskazole / Zentel

albendazole

Tablet;Suspension

Alternatives: Yes

Expected resolution: 2028

EMA shortage detail ↗

Shortage ongoing Tachycardia, Supraventricular · Hypertension Reported 02/09/2026

Brevibloc

esmolol

Solution for intravenous injection · 10 mg/ml

Alternatives: Yes

Expected resolution: End of 2027

EMA shortage detail ↗

Shortage ongoing Schizophrenia Reported 27/08/2026

Paliperidone palmitate

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Bacterial Infections Reported 10/07/2026

Azactam

aztreonam

Powder for solution for injection;Powder for solution for infusion · 1 g;2 g

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Reported 03/07/2026

Tegsedi

inotersen

Solution for injection in pre-filled syringe

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Tuberculosis · Acquired Immunodeficiency Syndrome Reported 30/06/2026

Mycobutin (rifabutin)

Capsule · 150 mg

Alternatives: Yes, in some Member States

Expected resolution: Expected to resolve by November 2026

EMA shortage detail ↗

Shortage ongoing Epilepsy · Migraine Disorders Reported 29/06/2026

Topamax

topiramate

Tablet · 25 mg, 50 mg, 100 mg and 200 mg

Alternatives: Yes

Expected resolution: End of 2026

EMA shortage detail ↗

Shortage ongoing Debridement Reported 06/05/2026

NexoBrid

concentrate of proteolytic enzymes enriched in bromelain

Alternatives: No

EMA shortage detail ↗

Shortage ongoing Reported 23/03/2026

Eli Lilly insulin (various forms)

Solution for injection;Suspension for injection

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Cancer Reported 24/02/2026

Cyclophosphamide

Powder for solution for injection or infusion

Alternatives: Unknown

Expected resolution: Expected to continue until Q1 2027.

EMA shortage detail ↗

Shortage ongoing Cancer Reported 13/02/2026

Ifosfamide

Powder for concentrate for solution for infusion

Alternatives: Unknown

Expected resolution: Expected to continue until Q1 2027.

EMA shortage detail ↗

Shortage ongoing Reported 08/12/2025

Insulin lispro Sanofi

insulin lispro

Solution for injection in a cartridge;Solution for injection in pre-filled pen · 100 units/ml solution for injection in cartridges;100 units/ml solution for injection in pre-filled pen

Alternatives: Yes

Expected resolution: The expected duration of the shortage is unknown.

EMA shortage detail ↗

Shortage ongoing Schizophrenia Reported 19/11/2025

Risperidone

Prolonged-release suspension for injection

Alternatives: Yes

Expected resolution: Risperdal Consta - by the end of 2025; Risperidone Teva and Sperizak - to continue until the end of 2026 or beginning of 2027

EMA shortage detail ↗

Shortage ongoing Reported 14/11/2025

Bronchitol

mannitol

Inhalation powder · 40 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Primary Immunodeficiency Diseases · Immunologic Deficiency Syndromes · Hepatitis A · Mucositis Reported 11/11/2025

Beriglobin

human normal immunoglobulin

Solution for injection in pre-filled syringe · 2 ml and 5 ml (160 mg/ml) solution

Alternatives: Depending on indication

EMA shortage detail ↗

Shortage ongoing Reported 12/05/2025

Fiasp PumpCart (insulin aspart)

insulin aspart

Solution for injection in a cartridge · 100 units/mL

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Reported 12/05/2025

NovoRapid PumpCart (insulin aspart)

insulin aspart

Solution for injection in a cartridge · 100 units/mL

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Reported 12/05/2025

NovoSeven (eptacog alfa)

eptacog alfa (activated)

Powder and solvent for solution for injection · 1, 2, 5 and 8 mg (50, 100, 250 and 400 KIU)

Alternatives: Unknown

Expected resolution: December 2025

EMA shortage detail ↗

Shortage ongoing Reported 14/04/2025

Dynastat

parecoxib

Powder and solvent for solution for injection;Powder for solution for injection · 40 mg

Alternatives: Unknown

Expected resolution: January 2026 in Malta; February 2026 in Greece; March 2026 in Cyprus and France; July 2026 in Bulgaria and Norway

EMA shortage detail ↗

Shortage ongoing Schizophrenia · Bipolar Disorder · Depressive Disorder Reported 11/03/2025

Quetiapine

Extended-release tablet · 50 mg;150 mg;200 mg;300 mg;400 mg

Alternatives: Yes

Expected resolution: Within the second quarter of 2027

EMA shortage detail ↗

Shortage ongoing Schizophrenia Reported 09/07/2024

Zypadhera

olanzapine

Powder and solvent for prolonged-release suspension for injection · 210 mg;300 mg;405 mg

Alternatives: Yes

Expected resolution: October 2025

EMA shortage detail ↗

Shortage ongoing Primary Immunodeficiency Diseases · Immunologic Deficiency Syndromes Reported 03/06/2024

Human normal immunoglobulins

Solution for injection/infusion

Alternatives: Yes

Expected resolution: To last until June 2026.

EMA shortage detail ↗

Shortage ongoing Pancreatic Diseases Reported 29/04/2024

Creon

pancreas powder;pancrelipase

Capsule · 10,000 units;25,000 units;35,000 units

Alternatives: Yes

Expected resolution: First half of 2027

EMA shortage detail ↗

Shortage ongoing Leukemia Reported 11/03/2024

Fludarabine

Concentrate for solution for injection/infusion · 25 mg/ml

Alternatives: Unknown

Expected resolution: The shortage is expected to last until December 2025.

EMA shortage detail ↗

Shortage ongoing Leukemia, Promyelocytic, Acute Reported 23/02/2024

Eldisine

vindesine

Solution for injection · 5 mg

Alternatives: Yes

Expected resolution: End of September 2025

EMA shortage detail ↗

Shortage ongoing Attention Deficit Disorder with Hyperactivity Reported 18/12/2023

ADHD medicines

atomoxetine;methylphenidate;lisdexamfetamine

Various presentations in various strengths

Alternatives: Yes

Expected resolution: Depending on the medicine and the EEA country, the shortage may continue until the end of 2025.

EMA shortage detail ↗

Shortage ongoing Diabetes Mellitus, Type 2 Reported 03/08/2023

Victoza

liraglutide

Pre-filled pen · 6 mg/ml

Alternatives: Yes

EMA shortage detail ↗

Shortage ongoing Diabetes Mellitus Reported 24/01/2023

Insuman Rapid, Basal and Comb 25 (insulin human)

insulin human

Solution for injection;Pre-filled pen · 3 ml

EMA shortage detail ↗

Shortage ongoing Myopia, Degenerative · Macular Degeneration Reported 08/11/2021

Visudyne

verteporfin

Powder for solution for infusion · 15 mg

Alternatives: Yes

Expected resolution: 2027

EMA shortage detail ↗

Shortage resolved Reported 31/10/2025

NovoNordisk insulin (human insulin) (various short-, rapid-, intermediate-, mixed- and long-acting forms)

Solution for injection;Suspension for injection · 100 units/ml

Alternatives: Yes

EMA shortage detail ↗

Medicine discontinued Trematode Infections Reported 26/08/2025

Biltricide

praziquantel

600 mg film-coated tablets

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Reported 18/08/2025

Moventig

12.5 mg;25 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Perfusion · Infusions, Intravenous · Therapeutic Irrigation Reported 12/06/2025

Perfusion solutions

Intravenous use;Solution for infusion;Irrigation solution

Alternatives: Yes

Expected resolution: End of 2025

EMA shortage detail ↗

Medicine discontinued Hypercalcemia · Parathyroid Neoplasms · Hyperparathyroidism Reported 07/04/2025

Mimpara

cinacalcet

Tablet;Granules in capsule · 30, 60, 90mg (tablets);1, 2.5, 5mg (granules in capsule)

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Candidiasis Reported 17/01/2025

Ecalta

anidulafungin

Powder for concentrate for solution for infusion · 100 mg

EMA shortage detail ↗

Shortage resolved Colorectal Neoplasms · Breast Neoplasms · Carcinoma, Non-Small-Cell Lung · Carcinoma, Renal Cell · Uterine Cervical Neoplasms Reported 17/01/2025

Zirabev

bevacizumab

Concentrate for solution for infusion · 100mg/4ml ;400mg/16ml

EMA shortage detail ↗

Shortage resolved Poisoning Reported 19/12/2024

Cyanokit

hydroxocobalamin

Powder for solution for infusion

EMA shortage detail ↗

Shortage resolved Hepatitis C, Chronic · Hepatitis B, Chronic · Polycythemia Vera · Thrombocythemia, Essential Reported 30/10/2024

Pegasys

peginterferon alfa-2a

Solution for injection · 90 mcg;135 mcg;180 mcg

EMA shortage detail ↗

Shortage resolved Cancer · Neoplasms Reported 06/08/2024

Cisplatin

Solution for injection

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Cancer · Neoplasms Reported 06/08/2024

Fluorouracil

Solution for injection/infusion

Expected resolution: 2025

EMA shortage detail ↗

Shortage resolved Asthma · Pulmonary Disease, Chronic Obstructive Reported 05/06/2024

Salbutamol inhalation products

salbutamol

Inhaler;Nebuliser solution

EMA shortage detail ↗

Shortage resolved Vomiting · Postoperative Nausea and Vomiting · Cancer · Neoplasms Reported 12/04/2024

Emend

aprepitant

Powder for oral suspension · 80 mg;125 mg

EMA shortage detail ↗

Medicine discontinued Angina, Unstable · Myocardial Infarction Reported 17/01/2024

Integrilin

eptifibatide

Solution for injection;Solution for infusion · 2 mg/ml (solution for injection);0.75 mg/ml (solution for infusion)

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Dwarfism, Pituitary Reported 05/12/2023

Norditropin FlexPro / Norditropin NordiFlex

somatropin

Solution for injection in pre-filled pen · 5 mg ;10 mg ;15 mg

Alternatives: Yes

Expected resolution: Resolved - 22 December 2025

EMA shortage detail ↗

Shortage resolved Ovarian Neoplasms · Uterine Cervical Neoplasms · Small Cell Lung Carcinoma Reported 07/11/2023

Hycamtin

topotecan

Capsule, hard · 0.5 mg;1 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Diabetes Mellitus, Type 2 Reported 28/08/2023

Trulicity

dulaglutide

Solution for injection in pre-filled pen · 0.75 mg;1.5 mg;3 mg ;4.5 mg

Alternatives: Yes

Expected resolution: End of 2025

EMA shortage detail ↗

Shortage resolved Obesity · Overweight Reported 24/08/2023

Saxenda

liraglutide

Solution for injection in pre-filled pen · 6 mg/ml

EMA shortage detail ↗

Shortage resolved Diabetes Mellitus Reported 24/08/2023

Tresiba

insulin degludec

Pre-filled pen · 100 units/ml ;200 units/ml

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Cancer · Neoplasms · Arthritis, Rheumatoid · Arthritis · Psoriasis · Crohn Disease Reported 09/08/2023

Methotrexate

Solution for injection · Various

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Diabetes Mellitus, Type 2 Reported 11/07/2023

Rybelsus

semaglutide

Tablet · 3 mg;7 mg;14 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Encephalitis, Japanese · Immunization Reported 25/05/2023

Ixiaro

Japanese encephalitis vaccine (inactivated, adsorbed)

Suspension for injection · 6AU

EMA shortage detail ↗

Shortage resolved Breast Neoplasms · Pancreatic Neoplasms · Carcinoma, Non-Small-Cell Lung Reported 11/05/2023

Abraxane

paclitaxel

Powder for dispersion for injection · 5 mg/ml

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Infertility Reported 05/04/2023

Menopur

menotropin

Powder and solvent for solution for injection · 1200 IU

Alternatives: Yes

Expected resolution: End of 2025

EMA shortage detail ↗

Shortage resolved Hyperuricemia Reported 21/02/2023

Fasturtec

rasburicase

Powder and solvent for concentrate for solution for infusion · 7.5 mg / 5 ml

EMA shortage detail ↗

Shortage resolved Bacterial Infections Reported 27/01/2023

Amoxicillin and amoxicillin/clavulanic acid

amoxicillin;clavulanic acid

Various presentations including paediatric formulations and presentations

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Breast Neoplasms Reported 26/01/2023

Pazenir

paclitaxel

Powder for dispersion for infusion · 5 mg/ml

EMA shortage detail ↗

Shortage resolved Diabetes Mellitus, Type 2 Reported 19/10/2022

Ozempic

semaglutide

Pre-filled pen · 1 mg;0.5 mg;0.25 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Myocardial Infarction Reported 23/09/2022

Actilyse and Actilyse Cathflo

alteplase

Powder and solvent for solution for injection/infusion · 10 mg (Actilyse);20 mg (Actilyse);50 mg (Actilyse);2 mg (Actilyse Cathflo)

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Myocardial Infarction Reported 23/09/2022

Metalyse

tenecteplase

Powder and solvent for solution for injection · 8,000 units (40 mg);10,000 units (50 mg)

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Ovulation · Ovulation Induction Reported 10/08/2022

Cetrotide

cetrorelix acetate

Powder and solvent for solution for infusion · 0.25 mg

Alternatives: Yes

EMA shortage detail ↗

Medicine discontinued Hypoparathyroidism Reported 02/05/2022

Natpar

parathyroid hormone

Powder and solvent for solution for injection · 100 micrograms/dose ;75 micrograms/dose ;50 micrograms/dose ;25 micrograms/dose

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Arthritis, Rheumatoid Reported 09/11/2021

Kevzara

sarilumab

Pre-filled syringe;Pre-filled pen;Solution for subcutaneous injection · 150 mg;200 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Arthritis, Rheumatoid · Arthritis, Juvenile Rheumatoid · Cytokine Release Syndrome · Giant Cell Arteritis · COVID-19 virus infection Reported 03/09/2021

RoActemra

tocilizumab

Pre-filled syringe;Pre-filled pen;Solution for subcutaneous injection;Concentrate for solution for infusion · 162 mg (syringe, pen) ;20 mg/ml (concentrate)

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Tobacco Use Cessation Reported 08/07/2021

Champix

varenicline

Film-coated tablet · 0.5 mg;1 mg

Alternatives: Yes

Expected resolution: June 2025

EMA shortage detail ↗

Shortage resolved Candidiasis · Mycoses · Aspergillosis Reported 16/04/2021

Vfend

voriconazole

Powder for solution for infusion · 200 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Genetic Diseases, Inborn · Lung Diseases Reported 06/04/2021

Respreeza

alpha1-proteinase inhibitor (human)

Powder and solvent for solution for infusion · 4,000 mg ;5,000 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Genetic Diseases, Inborn · Lung Diseases Reported 25/02/2021

Respreeza

alpha1-proteinase inhibitor (human)

Powder and solvent for solution for infusion · 1,000 mg ;4,000 mg ;5,000 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Asthma Reported 28/01/2021

Nucala

mepolizumab

Pre-filled pen · 40 mg ;100 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Bacterial Infections Reported 22/12/2020

Zerbaxa

ceftolozane;tazobactam

Concentrate for solution for infusion · 1 g;0.5 g

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Angioedemas, Hereditary Reported 06/08/2018

Cinryze

C1 inhibitor (human)

Powder and solvent for intravenous injection · 500 IU

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Leukemia, Promyelocytic, Acute Reported 31/07/2017

Trisenox

arsenic trioxide

Solution for infusion

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Venous Thrombosis · Pulmonary Embolism · Myocardial Infarction · Angina, Unstable Reported 07/07/2017

Arixtra

fondaparinux sodium

Pre-filled syringe · 1.5 mg;2.5 mg;5.0 mg;7.5 mg

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Graft Rejection · Kidney Transplantation Reported 17/03/2017

Nulojix

belatacept

Solution for infusion · 25 mg/ml

EMA shortage detail ↗

Shortage resolved Reproductive Techniques, Assisted · Ovulation Induction · Infertility, Female Reported 16/02/2017

Orgalutran

ganirelix

Solution for injection in pre-filled pen · 0.25 mg/0.5 ml

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Head and Neck Neoplasms · Carcinoma, Non-Small-Cell Lung · Adenocarcinoma · Prostatic Neoplasms · Stomach Neoplasms · Breast Neoplasms Reported 19/05/2016

Taxotere

docetaxel

Concentrate for solution for infusion · 20 mg;1 ml and 80g;4 ml

Alternatives: Yes

EMA shortage detail ↗

Medicine discontinued Diabetes Mellitus Reported 01/12/2015

Insuman Basal and Comb 25

insulin human

Catridge;Pre-filled pen · 3 ml

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Tibial Fractures · Fracture Fixation, Internal · Spinal Fusion Reported 16/09/2015

Inductos

dibotermin alfa

Powder, solvent and matrix for implantation matrix

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Bacterial Infections · Skin Diseases, Bacterial · Soft Tissue Infections Reported 22/05/2015

Tygacil

tigecycline

Powder for solution for infusion

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Diabetes Mellitus Reported 31/03/2015

Insuman Rapid, Basal and Comb

insulin human

Catridge;Pre-filled pen · 3 ml

Alternatives: Yes

EMA shortage detail ↗

Shortage resolved Prostatic Neoplasms Reported 17/10/2014

Xofigo

radium Ra223 dichloride

Solution for injection · 1100 kBq/ml

Alternatives: No

EMA shortage detail ↗

Shortage resolved Epilepsy Reported 25/04/2014

Buccolam

midazolam

Pre-filled syringe · 2.5 mg;5 mg;7.5 mg;10 mg

Alternatives: Not stated

EMA shortage detail ↗

Shortage resolved Spondylitis, Ankylosing · Arthritis, Juvenile Rheumatoid · Arthritis, Psoriatic · Psoriasis · Arthritis, Rheumatoid Reported 19/02/2014