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Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery ◆ Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma ◆ Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide ◆ The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany ◆ Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact ◆ The Pharmacist's Role: How Community Pharmacies in Ireland and the UK Are Adapting as Patients Bypass High-Street Stores for Direct Delivery ◆ GLP-1 Therapeutics and Clinical Research Updates: Brain Reward Mapping, Oral Small Molecules, and Triple-Agonist Horizons ◆ Rinn Pharma & Biopharma Joins NordicPharmaTrain Network to Accelerate European Research & Advanced Manufacturing ◆ Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery ◆ Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma ◆ Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide ◆ The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany ◆ Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact ◆ The Pharmacist's Role: How Community Pharmacies in Ireland and the UK Are Adapting as Patients Bypass High-Street Stores for Direct Delivery ◆ GLP-1 Therapeutics and Clinical Research Updates: Brain Reward Mapping, Oral Small Molecules, and Triple-Agonist Horizons ◆ Rinn Pharma & Biopharma Joins NordicPharmaTrain Network to Accelerate European Research & Advanced Manufacturing ◆
Updated 14 Sep 2026 · ClinicalTrials.gov

Clinical Trials in the USA

The most recently updated industry-sponsored clinical trials recruiting across the United States — searchable by condition, sponsor, phase and state. Refreshed daily from the ClinicalTrials.gov registry.

113
Recruiting now
160
Studies tracked
48
States with sites
Active Phase 3
A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and Adolescents With Moderate to Severe Hidradenitis Suppurativa
Hidradenitis Suppurativa
UCB Biopharma SRL · started 2025-04-07
Arizona · California · District of Columbia · Florida · Kentucky · Michigan · North Carolina · Ohio
NCT06921850 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors
Advanced Solid Tumor
BeOne Medicines · started 2025-12-11
Alabama · Connecticut · Maryland · Massachusetts · Texas · Wisconsin
NCT07226349 on ClinicalTrials.gov ↗
Active Phase 1
A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
AbbVie · started 2025-01-27
California · Montana · North Carolina · Texas
NCT06291220 on ClinicalTrials.gov ↗
Active Phase 1
Study of the Adverse Events and Change in Disease State of Pediatric Participants (and Young Adults Between the Ages of 18-25) With Relapsed/Refractory Aggressive Mature B-cell Neoplasms Receiving Subcutaneous (SC) Injections of Epcoritamab
Non-hodgkin Lymphoma
Genmab · started 2022-10-04
California · Florida · New York · North Carolina · Ohio · Pennsylvania · Tennessee · Texas
NCT05206357 on ClinicalTrials.gov ↗
Recruiting Phase 3
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Triple-Negative Breast Cancer
Merck Sharp & Dohme LLC · started 2024-06-24
Alabama · Arizona · California · Colorado · Connecticut · Delaware · Florida · Georgia
NCT06393374 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Non-Small Cell Lung Cancer (NSCLC)
Amgen · started 2023-11-16
California · Delaware · Florida · Illinois · Kentucky · Massachusetts · New Mexico · New York
NCT05920356 on ClinicalTrials.gov ↗
Recruiting Phase 3
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
Urothelial Cancer, Urinary Bladder Neoplasms
Astellas Pharma Global Development, Inc. · started 2026-05-11
California · Colorado · Delaware · Illinois · Indiana · Missouri · Ohio · Oregon
NCT07566156 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies
Primary Immune Thrombocytopenia (ITP)
Novartis Pharmaceuticals · started 2023-08-16
Massachusetts
NCT05885555 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma
BeOne Medicines · started 2021-09-13
Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Iowa
NCT05006716 on ClinicalTrials.gov ↗
Active
Case-Control Study of the Glycotest™ HCC Panel vs AFP for the Detection of Early-stage Hepatocellular Carcinoma
Carcinoma, Hepatocellular, Cirrhosis, Liver
Glycotest, Inc. · started 2019-05-22
California · Florida · Illinois · Maryland · Michigan · Minnesota · New York · Pennsylvania
NCT03878550 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's Disease
Parkinson's Disease
Hoffmann-La Roche · started 2017-06-27
Alabama · Arizona · California · Colorado · Connecticut · Florida · Illinois · Kansas
NCT03100149 on ClinicalTrials.gov ↗
Recruiting Phase 1
Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma
Ependymoma, High Grade Gliomas
Cerenome · started 2026-08-01
Illinois
NCT07061626 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor, Platinum-resistant Ovarian Cancer
Ascendis Pharma Oncology Division A/S · started 2022-01-11
California · Illinois · Kentucky · Massachusetts · New Jersey · New York · North Carolina · Ohio
NCT05081609 on ClinicalTrials.gov ↗
Active
Myopia Control With a Innovative Spectacle Lens - A Cessation Study
Myopia Progressing
Essilor International · started 2025-02-18
Illinois · Kansas · Massachusetts · New York
NCT06884527 on ClinicalTrials.gov ↗
Active Phase 2/Phase 3
LMN-201 for Prevention of C. Difficile Infection Recurrence
Clostridioides Difficile Infection
Lumen Bioscience, Inc. · started 2024-08-29
California · Connecticut · Florida · Illinois · Kentucky · Michigan · Minnesota · New York
NCT05330182 on ClinicalTrials.gov ↗
Recruiting Phase 3
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma
Multiple Myeloma
Hoffmann-La Roche · started 2026-06-23
California · Connecticut · District of Columbia · Georgia · North Carolina · Ohio · West Virginia
NCT07555938 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
Diabetes Mellitus, Type 2
Novo Nordisk A/S · started 2026-04-17
California · Florida · Idaho · Illinois · Massachusetts · Missouri · North Carolina · Ohio
NCT07415954 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC
Ovarian Cancer, Non-small Cell Lung Cancer
Tubulis GmbH · started 2024-06-12
Alabama · Connecticut · Georgia · Kentucky · Massachusetts · New Jersey · New York · Ohio
NCT06303505 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Breast Neoplasms, Triple Negative Breast Neoplasms, HR Low-Positive/HER2-Negative Breast Neoplasms
Merck Sharp & Dohme LLC · started 2025-06-30
Arizona · California · Colorado · Florida · Georgia · Indiana · Louisiana · Maine
NCT06966700 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer
Hormone Receptor Positive Early Breast Cancer
Rovi Pharmaceuticals Laboratories · started 2026-06-08
California · Florida
NCT07401381 on ClinicalTrials.gov ↗
Recruiting Phase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Attention-Deficit/Hyperactivity Disorder
Supernus Pharmaceuticals, Inc. · started 2024-03-19
Alabama · Arkansas · California · Colorado · Florida · Georgia · Indiana · Kentucky
NCT04781140 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma
Metastatic Urothelial Carcinoma, Metastatic Urothelial Carcinoma (UC)
Summit Therapeutics · started 2026-09-10
Arizona · California · District of Columbia · Florida · Minnesota · Tennessee · Washington
NCT07815665 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Ulcerative Colitis
AbbVie · started 2025-07-28
Arizona · California · Florida · Georgia · Illinois · New Jersey · Ohio · Pennsylvania
NCT07071519 on ClinicalTrials.gov ↗
Recruiting
The PERSEVERE Study
Pulmonary Embolism, Pulmonary Thromboembolism
Inari Medical · started 2024-12-16
Connecticut · Florida · Georgia · Mississippi · New York · Ohio · Pennsylvania · Tennessee
NCT06588634 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.
Crohn's Disease
Sanofi · started 2024-12-10
Arizona · Connecticut · Florida · Illinois · Michigan · Mississippi · Nevada · New York
NCT06637631 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
Bladder Cancer
Merck Sharp & Dohme LLC · started 2026-04-23
District of Columbia · Maryland · Michigan · New Jersey · New York · North Carolina · Ohio · Tennessee
NCT07419295 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
Small Cell Lung Cancer
AbbVie · started 2026-07-02
Alabama · Arizona · California · Florida · Georgia · Illinois · Indiana · Massachusetts
NCT07365241 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
BeOne Medicines · started 2026-01-22
California · Colorado · Florida · Illinois · Louisiana · Massachusetts · Minnesota · Nebraska
NCT07277231 on ClinicalTrials.gov ↗
Recruiting Phase 3
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
Glioblastoma, Recurrent Glioblastoma, GBM
CarThera · started 2024-01-29
Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana · Maryland
NCT05902169 on ClinicalTrials.gov ↗
By invitation Phase 3
An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE)
Biogen · started 2022-06-10
Arizona · California · Colorado · District of Columbia · Florida · Georgia · Massachusetts · Michigan
NCT05352919 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia
Acute Myeloid Leukemia (AML), FLT3-mutated Acute Myeloid Leukemia
Astellas Pharma Global Development, Inc. · started 2023-01-31
California · Colorado · Florida · Illinois · Maryland · New York · North Carolina · Ohio
NCT05520567 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma, Burkitt Lymphoma, Neuroblastoma
Merck Sharp & Dohme LLC · started 2024-08-16
California · Colorado · Connecticut · Florida · Iowa · Massachusetts · Michigan · Missouri
NCT06395103 on ClinicalTrials.gov ↗
Starting soon Phase 3
A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Migraine
Kallyope Inc. · started 2026-09
Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia · Idaho
NCT07816367 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
Asthma
Teva Branded Pharmaceutical Products R&D LLC · started 2023-08-30
Alabama · Arizona · California · Colorado · District of Columbia · Florida · Georgia · Idaho
NCT06052267 on ClinicalTrials.gov ↗
Active Phase 3
Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)
Non-small Cell Lung Cancer (NSCLC)
Merck Sharp & Dohme LLC · started 2024-06-11
California · Florida · Georgia · Michigan · Missouri · New Jersey · New York · North Dakota
NCT06305754 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease
Primary Membranous Nephropathy
AstraZeneca · started 2026-03-28
California · Iowa · Maryland · New York · Texas
NCT07571746 on ClinicalTrials.gov ↗
Active Phase 2
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Chronic Hepatitis B Infection
Aligos Therapeutics · started 2025-07-15
California · Florida
NCT06963710 on ClinicalTrials.gov ↗
Active Phase 2
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis
Gilead Sciences · started 2023-12-05
Arizona · California · Florida · Michigan · Minnesota · Mississippi · Missouri · New York
NCT06029972 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)
Lymphoma, Non-Hodgkin, Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse
Merck Sharp & Dohme LLC · started 2026-05-03
Colorado · Tennessee
NCT07519772 on ClinicalTrials.gov ↗
Recruiting Phase 3
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Obesity, Overweight, Obstructive Sleep Apnoea
Novo Nordisk A/S · started 2026-05-05
California · Florida · Georgia · Illinois · New York · Ohio · Pennsylvania · Texas
NCT07571005 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study of Resmetirom in Children and Adolescents With MASH
MASH, MASH - Metabolic Dysfunction-Associated Steatohepatitis
Madrigal Pharmaceuticals, Inc. · started 2026-08-01
Indiana
NCT07763015 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer, Carcinoma Non Small Cell Lung
Regeneron Pharmaceuticals · started 2026-03-18
Alabama · Arizona · California · District of Columbia · Florida · Illinois · Indiana · Maryland
NCT07154290 on ClinicalTrials.gov ↗
Recruiting
Advanta VXT and Flixene PMCF Registry
Peripheral Arterial Disease
Atrium Medical Corporation · started 2025-09-25
Massachusetts
NCT07161583 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Asthma
AstraZeneca · started 2023-08-24
Alabama · Arizona · Arkansas · California · Georgia · Maryland · Massachusetts · Michigan
NCT06023589 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment
Psoriatic Arthritis
Bristol-Myers Squibb · started 2021-07-15
Alabama · California · Illinois · Kentucky · Louisiana · Maryland · Michigan · Minnesota
NCT04908189 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Obesity, Overweight, Chronic Weight Management, Type2 Diabetes Mellitus
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics · started 2026-07-17
Alabama · Arizona · Arkansas · California · Connecticut · Florida · Georgia · Idaho
NCT07654374 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients
Small Cell Lung Cancer Extensive Stage
Genprex, Inc. · started 2024-05-09
Colorado · Missouri · Ohio · Oregon · Texas · Virginia · Washington
NCT05703971 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
Non Small Cell Lung Cancer
Merck Sharp & Dohme LLC · started 2024-04-03
Arkansas · California · Connecticut · Florida · Georgia · Illinois · Indiana · Kentucky
NCT06312137 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma
Metastatic Soft Tissue Sarcoma, Unresectable Soft Tissue Sarcoma
Adcendo ApS · started 2025-06-05
Colorado · Florida · New York · Texas
NCT06797999 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Clinical Study of MK-8294 in Participants With Advanced Solid Tumors (MK-8294-001)
Metastatic Neoplasm
Merck Sharp & Dohme LLC · started 2025-07-23
Illinois · New Jersey · Texas
NCT07030712 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
Castration-Resistant Prostatic Cancer, Metastasis
Merck Sharp & Dohme LLC · started 2025-07-03
California · District of Columbia · Michigan · New York · Pennsylvania · Tennessee · Washington
NCT06863272 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
Advanced Solid Tumors, HNSCC, SCLC, NSCLC
Tubulis GmbH · started 2024-12-13
Connecticut · Florida · Massachusetts · Minnesota · Missouri · New York · Ohio · Texas
NCT06657222 on ClinicalTrials.gov ↗
By invitation Phase 3
Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Viatris Innovation GmbH · started 2024-07-30
Colorado · Florida · Louisiana · Nevada · Texas
NCT06475742 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer
Small Cell Lung Cancer
AbbVie · started 2025-11-25
Connecticut · Florida · Indiana · Kentucky · Massachusetts · Missouri · Ohio · Texas
NCT07155174 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
BeOne Medicines · started 2022-03-10
California · Florida · Georgia · Illinois · Indiana · Iowa · Kansas · Kentucky
NCT05100862 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
Crohn's Disease
AbbVie · started 2023-12-11
Arizona · Arkansas · California · Colorado · Florida · Indiana · Massachusetts · Minnesota
NCT05995353 on ClinicalTrials.gov ↗
Recruiting
Post Market Clinical Study to Evaluate the Performance of the Versius Surgical System
Cholecystectomy, Robotic
CMR Surgical Ltd · started 2026-03-23
California · Texas
NCT07096856 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
Crohn's Disease, Ulcerative Colitis
AbbVie · started 2026-07-31
Alabama · Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois
NCT07697456 on ClinicalTrials.gov ↗
Recruiting
Intervascular Post-Market Clinical Follow-Up (PMCF) Registry
Carotid Artery Diseases, Aortic Diseases, Peripheral Arterial Diseases
Intervascular · started 2025-12-19
Pennsylvania
NCT07322913 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis
Ocular Myasthenia Gravis
UCB Biopharma SRL · started 2026-05-27
Arizona · Illinois · New York · Ohio · Wisconsin
NCT07463521 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer
Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma
Astellas Pharma Global Development, Inc. · started 2026-06-30
Minnesota
NCT07673887 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma
Follicular Lymphoma (FL)
Regeneron Pharmaceuticals · started 2023-12-12
Arizona · California · Indiana · Massachusetts · Michigan · Mississippi · New York · North Carolina
NCT06091254 on ClinicalTrials.gov ↗
Active
Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing
Tachycardia, Ventricular, Arrhythmia, Ventricular
Boston Scientific Corporation · started 2021-07-20
Arizona · Arkansas · Florida · Georgia · Kentucky · Minnesota · New Jersey · New York
NCT04798768 on ClinicalTrials.gov ↗
Active Phase 1
[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer
Breast Cancer
Novartis Pharmaceuticals · started 2023-11-13
California · Texas
NCT05870579 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
Malignant Neoplasm
Merck Sharp & Dohme LLC · started 2026-07-06
Colorado · Iowa · Massachusetts · Michigan · New Jersey · New York · North Dakota · Pennsylvania
NCT07630974 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Extensive-Stage Small Cell Lung Cancer
Bristol-Myers Squibb · started 2025-02-25
Alabama · Arkansas · Florida · Georgia · Illinois · Minnesota · New Mexico · North Carolina
NCT06646276 on ClinicalTrials.gov ↗
Recruiting Phase 3
Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy
Generalized Lipodystrophy
Regeneron Pharmaceuticals · started 2026-03-13
Michigan · Texas
NCT07220785 on ClinicalTrials.gov ↗
Recruiting
Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
Heart Failure, Heart Failure NYHA Class II, Heart Failure NYHA Class III
CVRx, Inc. · started 2026-04-24
Alabama · Florida · Ohio · South Dakota · Tennessee · Texas · Wisconsin
NCT07232030 on ClinicalTrials.gov ↗
Recruiting
RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Pain
Boston Scientific Corporation · started 2012-11-19
Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana · Kansas
NCT01719055 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort
Duchenne Muscular Dystrophy
Sarepta Therapeutics, Inc. · started 2020-11-23
Arkansas · California · Florida · Illinois · Missouri · North Carolina · Ohio · Texas
NCT04626674 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis
Atopic Dermatitis
UCB Biopharma SRL · started 2025-12-29
California · Florida · Georgia · Illinois · Indiana · Kentucky · Michigan · Nebraska
NCT07277660 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Heart Failure and Impaired Kidney Function
AstraZeneca · started 2024-04-12
Alabama · Arizona · Arkansas · California · Colorado · Florida · Georgia · Illinois
NCT06307652 on ClinicalTrials.gov ↗
Starting soon
A Prospective Study Comparing CSF Shunt Flow Between "Virtual Off" and "Flow Permissive" Shunt Valve Settings Using a Wireless, Noninvasive Shunt Flow Sensor
Hydrocephalus
Rhaeos, Inc. · started 2026-09-08
Illinois
NCT07815314 on ClinicalTrials.gov ↗
Recruiting Phase 1
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
Advanced Solid Tumor, Advanced Breast Cancer, Metastatic Breast Cancer, Hormone-receptor-positive Breast Cancer
BeOne Medicines · started 2023-12-01
Colorado · Florida · Michigan · Missouri · North Carolina · Ohio · Tennessee · Texas
NCT06120283 on ClinicalTrials.gov ↗
Active Phase 1
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Cancer
Tizona Therapeutics, Inc · started 2020-07-14
Arizona · California · Colorado · Connecticut · Delaware · District of Columbia · Florida · Illinois
NCT04485013 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia (wAIHA)
Novartis Pharmaceuticals · started 2022-12-30
Michigan · Minnesota · Washington
NCT05648968 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study Assessing Safety, Tolerability, and Efficacy of INNA-051 in Preventing Respiratory Illness Due to Viral Infections in Healthy Adults 18 to 45 Years of Age
Viral Respiratory Infection, Viral Respiratory Illnesses
ENA Respiratory Pty Ltd · started 2025-12-04
Maryland · North Carolina
NCT07222670 on ClinicalTrials.gov ↗
Active Phase 3
Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension
Hypertension
Mineralys Therapeutics Inc. · started 2023-07-14
Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Idaho
NCT05968430 on ClinicalTrials.gov ↗
Active
CHAMPION-AF Clinical Trial
Atrial Fibrillation, Stroke, Bleeding
Boston Scientific Corporation · started 2020-10-15
Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Delaware · District of Columbia
NCT04394546 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis
Colitis Ulcerative
Sanofi · started 2025-03-28
Arizona · Connecticut · Florida · Illinois · Michigan · New York · Ohio · Pennsylvania
NCT06867094 on ClinicalTrials.gov ↗
Recruiting
Falcon Real World Evidence Registry
Cancer
Exact Sciences Corporation · started 2024-08-01
Illinois · Texas
NCT06589310 on ClinicalTrials.gov ↗
Recruiting Phase 4
Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS)
Relapsed/Refractory Multiple Myeloma (RRMM)
Regeneron Pharmaceuticals · started 2026-07-15
California · Louisiana · Maryland · Washington
NCT07609940 on ClinicalTrials.gov ↗
Active Phase 3
AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy.
Stage IB-IIIA Non-small Cell Lung Carcinoma
AstraZeneca · started 2015-10-21
California · Colorado · Connecticut · Florida · Georgia · Hawaii · Illinois · Maryland
NCT02511106 on ClinicalTrials.gov ↗
Active Phase 1
Phase I/II Study of [225Ac]Ac-PSMA-R2 in PSMA-positive Prostate Cancer, With/Without Prior 177Lu-PSMA RLT
Prostate Cancer
Novartis Pharmaceuticals · started 2023-11-07
Minnesota
NCT05983198 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
Hepatic Impairment
Insmed Incorporated · started 2026-07-14
California · Florida · Texas
NCT07643155 on ClinicalTrials.gov ↗
Active Phase 2/Phase 3
A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
Breast Cancer
Hoffmann-La Roche · started 2020-01-29
California · Massachusetts · New York · North Carolina · Tennessee · Texas · Washington
NCT04191499 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis
CKD, Metabolic Acidosis
Renibus Therapeutics, Inc. · started 2026-01-13
California · Colorado · Delaware · Florida · Georgia · Idaho · Illinois · Indiana
NCT07355062 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
Non Small Cell Lung Carcinoma
AbbVie · started 2025-03-06
Arizona · California · Colorado · Florida · Illinois · Indiana · Kansas · Massachusetts
NCT06772623 on ClinicalTrials.gov ↗
Active Phase 2
Study of Durvalumab+Olaparib or Durvalumab After Treatment With Durvalumab and Chemotherapy in Patients With Lung Cancer (ORION)
Non-small Cell Lung Cancer NSCLC
AstraZeneca · started 2018-12-21
Florida · Missouri · Pennsylvania · Tennessee · Texas
NCT03775486 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors
Sub-study 1 Cervical Cancer (Volrustomig Monotherapy), Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy), Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy), Sub-study 4 Esophageal Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy)
AstraZeneca · started 2024-08-22
California · Maryland · New York · Ohio · Pennsylvania
NCT06535607 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)
Diffuse Large B-Cell Lymphoma
Genmab · started 2023-02-08
Arizona · Arkansas · California · Colorado · Florida · Hawaii · Illinois · Indiana
NCT05578976 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
PARKINSON DISEASE (Disorder)
Vima Therapeutics · started 2026-09
Arizona · California · Connecticut · Florida · Georgia · Kansas · Maryland · Michigan
NCT07804615 on ClinicalTrials.gov ↗
Recruiting
Identification and Validation of Blood-Based Biomarkers for Early Detection of Asymptomatic Lung Cancer in High-Risk Heavy Smokers
Lung Cancers
Everest Detection, Inc. · started 2025-02-17
Oklahoma
NCT06816121 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Hemophilia B
Regeneron Pharmaceuticals · started 2024-09-11
California · Colorado · Connecticut · Florida · Indiana · Louisiana · Michigan · Ohio
NCT06379789 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers
Recurrent Ovarian Cancer, Recurrent Fallopian Tube Cancer, Recurrent Primary Peritoneal Cancer, Recurrent Endometrial Cancer
Regeneron Pharmaceuticals · started 2018-05-21
Alabama · Massachusetts · Minnesota · New York · Ohio · Oklahoma · Tennessee · Virginia
NCT03564340 on ClinicalTrials.gov ↗
Active Phase 2/Phase 3
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus
Biogen · started 2022-09-13
Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana
NCT05531565 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence
Narcolepsy Type 1, Narcolepsy Type 2
Centessa Pharmaceuticals (UK) Limited · started 2026-05-29
Alabama · Colorado · Florida · Georgia · Mississippi · North Carolina · Ohio · South Carolina
NCT07598708 on ClinicalTrials.gov ↗
Recruiting Phase 3
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
Arthritis, Psoriatic
MoonLake Immunotherapeutics AG · started 2024-10-15
Arizona · Arkansas · California · Florida · Georgia · Illinois · Louisiana · Maryland
NCT06641089 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
Hemophilia A
Hoffmann-La Roche · started 2026-09-08
California
NCT07226206 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
Type 2 Diabetes Mellitus (T2DM)
Amgen · started 2024-11-07
Alabama · California · Florida · Georgia · Illinois · Louisiana · Michigan · Montana
NCT06660173 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study Investigating the Safety of RO7795081 and How the Body Processes RO7795081 in People With Normal or Decreased Kidney Functions
Renal Impairment
Hoffmann-La Roche · started 2026-09-09
Florida
NCT07741604 on ClinicalTrials.gov ↗
Recruiting
ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain
Greater Trochanteric Pain Syndrome, Greater Trochanteric Pain Syndrome of Both Lower Limbs, Lateral Hip Pain
Brixton Biosciences, Inc. · started 2026-07-27
Arizona · Georgia · Louisiana · Massachusetts · New Jersey · Oklahoma · Pennsylvania · Texas
NCT07568015 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)
Malignant Neoplasm
Merck Sharp & Dohme LLC · started 2025-12-16
New Jersey · Texas · Virginia
NCT07247110 on ClinicalTrials.gov ↗
Active Phase 2/Phase 3
A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy
Primary Membranous Nephropathy
BeOne Medicines · started 2023-04-17
California · Minnesota · Nevada
NCT05707377 on ClinicalTrials.gov ↗
Recruiting
Getinge's Beating Heart Product Family Post-Market Clinical Follow-up (PMCF) Study
Off Pump Coronary Artery Bypass Surgery
Maquet Cardiovascular · started 2026-03-04
California · Wisconsin
NCT07286890 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma
Metastatic Castration-Resistant Prostate Cancer (mCRPC), Clear Cell Renal Cell Carcinoma (ccRCC)
Regeneron Pharmaceuticals · started 2026-07-20
Arizona · California · Florida · Illinois · Texas
NCT07594106 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
Alzheimer's Disease
AbbVie · started 2026-05-15
California · Colorado · Florida · Massachusetts · Tennessee · Texas
NCT07599670 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Metastatic Colorectal Cancer
Hoffmann-La Roche · started 2021-10-22
Alabama · Arizona · California · Colorado · Connecticut · Florida · Illinois · Louisiana
NCT04929223 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
BeOne Medicines · started 2025-09-04
Alabama · Arizona · California · Delaware · District of Columbia · Florida · Illinois · Iowa
NCT06973187 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis
Non-cystic Fibrosis Bronchiectasis
UCB Biopharma SRL · started 2026-08-05
Florida · Pennsylvania · Texas
NCT07720375 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)
Bladder Cancer, Urinary Bladder Neoplasms
Merck Sharp & Dohme LLC · started 2025-12-09
California · New Jersey · South Carolina · Texas
NCT07222488 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer, Endometrial Cancer
AstraZeneca · started 2021-10-18
California · Louisiana · Maryland · Massachusetts · Missouri · New Mexico · New York · North Carolina
NCT05123482 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)
Cervical Cancer
Merck Sharp & Dohme LLC · started 2026-01-19
Florida · Georgia · Louisiana · Maryland · Minnesota · Nevada · New York · Ohio
NCT07216703 on ClinicalTrials.gov ↗
Active
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)
Non-Small Cell Lung Cancer
Razor Genomics · started 2020-09-11
California · Florida · Kentucky · Missouri · New Jersey · North Carolina · Oklahoma · Pennsylvania
NCT01817192 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Endometrial Cancer
Merck Sharp & Dohme LLC · started 2025-05-22
Alabama · Alaska · California · Connecticut · District of Columbia · Florida · Georgia · Illinois
NCT06952504 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. · started 2022-06-07
California · Illinois · Kansas · New Jersey · New York · North Carolina · Texas · Washington
NCT05365581 on ClinicalTrials.gov ↗
Recruiting
A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling Surgeons
Open Surgery, Lymphedema, Free Tissue Transfer, Microsurgery
MMI (Medical Microinstruments, Inc.) · started 2025-09-22
California · Connecticut · Florida · New York · Ohio
NCT06725030 on ClinicalTrials.gov ↗
Recruiting Phase 1
Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors
Advanced Solid Tumor
BeOne Medicines · started 2024-10-18
New Jersey · Texas · Virginia · Wisconsin
NCT06598800 on ClinicalTrials.gov ↗
Active Phase 2
A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC
Prostatic Neoplasm
Novartis Pharmaceuticals · started 2024-01-03
Colorado · Georgia · Indiana · Iowa · Nebraska · Oregon · Pennsylvania · Texas
NCT05849298 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate MAR002 for Acromegaly
Acromegaly
Marea Therapeutics · started 2026-07-23
Arizona · Ohio · Texas
NCT07641179 on ClinicalTrials.gov ↗
Active
The PEERLESS II Study
Pulmonary Embolism
Inari Medical · started 2023-11-17
Alabama · California · Colorado · Connecticut · Florida · Georgia · Illinois · Michigan
NCT06055920 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE)
EMD Serono Research & Development Institute, Inc. · started 2026-03-10
California · Florida · Georgia · Michigan · Texas
NCT07332481 on ClinicalTrials.gov ↗
Recruiting Phase 1
Phase 1 Study Involving SAB01 and Healthy Participants
Healthy Adult Participants
Santa Ana Bio · started 2026-08-31
California
NCT07815561 on ClinicalTrials.gov ↗
Active Phase 2
Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer
Gilead Sciences · started 2022-05-30
Alaska · California · Colorado · District of Columbia · Florida · Georgia · Illinois · Kansas
NCT05186974 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET
Somatostatin Receptor Positive (SSTR+), Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET)
Novartis Pharmaceuticals · started 2025-05-30
Arizona · Arkansas · Colorado · Connecticut · Florida · Georgia · Kentucky · Louisiana
NCT06784752 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults
Pulmonary Arterial Hypertension
35Pharma Inc · started 2026-08-19
Florida · Rhode Island
NCT07143448 on ClinicalTrials.gov ↗
Recruiting Phase 2
NOV-ERA - A Clinical Trial to Assess the Efficacy and Safety of Ontunisertib Compared to Placebo in Patients With Fibrostenosing Crohn's Disease
Fibrostenotic Crohn's Disease
Agomab Spain S.L.U. · started 2026-10-30
Florida · Texas
NCT07683325 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
Breast Cancer
Novartis Pharmaceuticals · started 2024-08-14
California · Minnesota · Texas · Wisconsin
NCT06247995 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
Advanced/Metastatic Non-Small Cell Lung Cancer, Carcinoma, Non-Small Cell Lung, Non-Small Cell Lung Cancer
Pfizer · started 2026-01-30
Arkansas · California · Colorado · Florida · New Jersey · New York · Oregon · Texas
NCT07227298 on ClinicalTrials.gov ↗
Recruiting
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
Liver Neoplasms, Primary Liver Cancer, Secondary Liver Cancer, Tumor Liver
HistoSonics, Inc. · started 2024-10-14
California · Florida · Georgia · Illinois · Louisiana · Maryland · Massachusetts · Michigan
NCT06486454 on ClinicalTrials.gov ↗
Recruiting Phase 1
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
Autosomal Dominant Polycystic Kidney Disease
AstraZeneca · started 2025-11-10
Alabama · California · Florida · Kansas · Maryland · Minnesota · Texas
NCT07228364 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)
Ovarian Cancer Recurrent
Merck Sharp & Dohme LLC · started 2025-04-15
Connecticut · Kentucky · Louisiana · Massachusetts · New York · Oklahoma · Texas · Utah
NCT06843447 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC · started 2026-04-09
Georgia · Missouri · New York · Tennessee
NCT07489495 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
Stereotypical Prolonged Seizures
UCB Biopharma SRL · started 2021-12-07
Arizona · Arkansas · California · Connecticut · District of Columbia · Florida · Hawaii · Idaho
NCT05077904 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
Obesity
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics · started 2025-12-29
California · Georgia · Minnesota · Missouri · Texas
NCT07815678 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
Ovarian Neoplasms, Ovarian Cancer
Merck Sharp & Dohme LLC · started 2026-02-16
Alabama · California · Florida · Georgia · Illinois · Indiana · Louisiana · Maine
NCT07318558 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
Hemophilia A
Hoffmann-La Roche · started 2023-09-21
California · District of Columbia · Indiana · Iowa
NCT05987449 on ClinicalTrials.gov ↗
Recruiting
Clinical Performance of AH Plus Jet® Root Canal Sealers in Single-cone Protocols
Root Canal Treatment
Dentsply Sirona Implants and Consumables · started 2026-09-09
New York
NCT07642284 on ClinicalTrials.gov ↗
Recruiting
SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation
Non-small Cell Lung Cancer, Colorectal Cancer, Breast Cancer
Guardant Health, Inc. · started 2023-10-25
Illinois
NCT05935384 on ClinicalTrials.gov ↗
Recruiting Phase 2
Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL
Relapsed or Refractory Aggressive B-Cell Non-Hodgkins Lymphoma
Hoffmann-La Roche · started 2025-03-05
Alaska · California · Colorado · Florida · Idaho · Illinois · Iowa · Kentucky
NCT06806033 on ClinicalTrials.gov ↗
Active Phase 3
177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer
Prostatic Neoplasms
Novartis Pharmaceuticals · started 2021-06-15
Colorado · Florida · Louisiana · Massachusetts · Missouri · Nebraska · New York · North Carolina
NCT04689828 on ClinicalTrials.gov ↗
By invitation
Health and Financial Impact on the Use of a Personal Exoskeleton in the Home and Community: a Case Study
Spinal Cord Injury
Ekso Bionics · started 2025-08-04
California
NCT07030322 on ClinicalTrials.gov ↗
Active Phase 2
A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (acelERA Breast Cancer)
Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
Hoffmann-La Roche · started 2020-11-27
Georgia · Ohio · Oregon
NCT04576455 on ClinicalTrials.gov ↗
Active Phase 3
AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss
Obesity
Novo Nordisk A/S · started 2026-04-21
Alabama · California · Florida · Illinois · Indiana · North Carolina · Pennsylvania · Rhode Island
NCT07503210 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
DLBCL, Diffuse Large B-Cell Lymphoma
Merck Sharp & Dohme LLC · started 2022-01-14
Arizona · California · Florida · Illinois · Kentucky · Maryland · Massachusetts · Michigan
NCT05139017 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Metastatic Castration-resistant Prostate Cancer
Amgen · started 2025-11-28
Arizona · California · Colorado · Connecticut · Delaware · Florida · Georgia · Illinois
NCT07213674 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Multiple Myeloma
AbbVie · started 2025-07-23
California · Connecticut · Massachusetts · Michigan · New York · North Carolina · Oregon · Texas
NCT06953960 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Prostate Cancer, Prostatic Neoplasms
Merck Sharp & Dohme LLC · started 2025-05-13
Arizona · California · Colorado · Connecticut · District of Columbia · Florida · Georgia · Illinois
NCT06925737 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Type 1 Diabetes Mellitus, T1D, T1DM, T1DM - Type 1 Diabetes Mellitus
COUR Pharmaceutical Development Company, Inc. · started 2025-05-12
Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois · Indiana
NCT06783309 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage
Glaucoma
Astellas Pharma Global Development, Inc. · started 2026-08-14
Massachusetts
NCT07770685 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase 1 Dose-escalation and Expansion Study of In Vivo BCMA-CAR T Cell Therapy (VV169) in Patients With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma Refractory, Multiple Myeloma in Relapse
Vyriad, Inc. · started 2026-09-08
Minnesota
NCT07802717 on ClinicalTrials.gov ↗
Recruiting
M-2018-334 in Hematological Malignancies
Hematological Malignancies
Miltenyi Biomedicine GmbH · started 2026-08-21
California
NCT06225050 on ClinicalTrials.gov ↗
Starting soon Phase 3
iSCIB1+ in Combination With Ipilimumab and Nivolumab as First-Line Treatment for Advanced Unresectable Melanoma
Melanoma (Skin Cancer), Advanced Melanoma, Metastatic Melanoma, Skin Cancer
Scancell Ltd · started 2026-12-01
Colorado
NCT07815574 on ClinicalTrials.gov ↗
Recruiting Phase 2
Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.
Refractory Angina, Coronary Artery Disease
XyloCor Therapeutics, Inc. · started 2025-07-08
Alabama · Arizona · Georgia · Massachusetts · Michigan · Minnesota · New York · North Carolina
NCT07048808 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
Diffuse Large B-Cell Lymphoma
Merck Sharp & Dohme LLC · started 2025-01-27
Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana
NCT06717347 on ClinicalTrials.gov ↗
Active
SIMPLAAFY Clinical Trial
Atrial Fibrillation, Stroke, Bleeding
Boston Scientific Corporation · started 2024-10-01
Alabama · Arizona · Arkansas · California · Colorado · Connecticut · District of Columbia · Florida
NCT06521463 on ClinicalTrials.gov ↗
Recruiting Phase 3
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma
Immuneering Corporation · started 2026-06-05
Alabama · Arizona · California · Colorado · Delaware · Florida · Georgia · Illinois
NCT07562152 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
HER2-positive Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
AstraZeneca · started 2025-03-01
Alaska · Arizona · California · Colorado · Delaware · Florida · Georgia · Illinois
NCT06764875 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Diabetic Macular Edema
Genentech, Inc. · started 2026-04-21
Arizona · California · Florida · Maryland · Pennsylvania · Tennessee · Texas · Virginia
NCT07425522 on ClinicalTrials.gov ↗
Recruiting
Observational Pharmaco-Epidemiology Research & Analysis
Chronic Disease, HIV/AIDS, Liver Diseases, Inflammatory Bowel Diseases
Epividian · started 2013-12-01
North Carolina
NCT03813862 on ClinicalTrials.gov ↗
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Priya Life Science (2026). Clinical Trials in the USA Tracker. Available at: https://priyalifescience.com/clinical-trials-usa (Accessed: 14 September 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one US site, most recently updated first, refreshed daily. This is a curated slice of the full registry, not every US trial. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish and EU sites, see our Ireland and EU trackers.