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Updated 08 Jul 2026 · ClinicalTrials.gov

Clinical Trials in the USA

The most recently updated industry-sponsored clinical trials recruiting across the United States — searchable by condition, sponsor, phase and state. Refreshed daily from the ClinicalTrials.gov registry.

112
Recruiting now
160
Studies tracked
46
States with sites
Recruiting Phase 2
Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer
Non-small Cell Lung Cancer (NSCLC)
Genmab · started 2026-01-30
📍 California · District of Columbia · Florida · Nebraska · New Jersey · New York · North Carolina · Tennessee
NCT07288177 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
Malignant Solid Tumor, Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Melanoma
Genmab · started 2019-09-17
📍 Alaska · California · Connecticut · Delaware · Florida · Illinois · Kentucky · Maryland
NCT04083599 on ClinicalTrials.gov ↗
Recruiting
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
Kuros Biosurgery AG · started 2024-06-10
📍 Connecticut · Illinois · Maryland · Michigan · North Carolina · Ohio · Utah · Virginia
NCT05037968 on ClinicalTrials.gov ↗
Recruiting
A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics
Prostatic Neoplasms, Metastatic Hormone-Sensitive Prostate Cancer
Bayer · started 2025-07-22
📍 Ohio
NCT07406282 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Type 2 Diabetes
Eli Lilly and Company · started 2025-03-28
📍 Arizona · California · Florida · Georgia · Idaho · Indiana · New Jersey · New York
NCT06897475 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Long-term Extension Study of PCI-32765 (Ibrutinib)
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma
Janssen Research & Development, LLC · started 2013-09-09
📍 California · Connecticut · Georgia · Illinois · Indiana · Kansas · Kentucky · Massachusetts
NCT01804686 on ClinicalTrials.gov ↗
Recruiting Phase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Osteoarthritis, Overweight or Obesity
Eli Lilly and Company · started 2026-02-09
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois
NCT07353931 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
Prostate Cancer, Metastatic Castration-Resistant Prostate Cancer, Metastatic Hormone Sensitive Prostate Cancer
Astellas Pharma Global Development, Inc. · started 2025-06-19
📍 Alabama · California · Florida · Illinois · Louisiana · New Mexico · Ohio · South Carolina
NCT07005154 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus
Boehringer Ingelheim · started 2026-04-20
📍 California · Colorado · Florida · Michigan · Mississippi · Montana · North Carolina · Ohio
NCT07409181 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
Alzheimers Disease
Hoffmann-La Roche · started 2025-11-12
📍 Arizona · California · Connecticut · Florida · Georgia · Illinois · Massachusetts · Michigan
NCT07170150 on ClinicalTrials.gov ↗
Starting soon Phase 1/Phase 2
A Phase I/II Trial of JR-446 in Mucopolysaccharidosis Type IIIB (MPS IIIB)
Mucopolysaccharidosis IIIB
JCR Pharmaceuticals Co., Ltd. · started 2026-06-18
📍 California · Pennsylvania · Virginia
NCT07640984 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease
Respiratory Syncytial Virus Infections
Shionogi · started 2025-12-11
📍 California · Florida · Georgia · Massachusetts · Missouri · New York · North Carolina · Ohio
NCT07214571 on ClinicalTrials.gov ↗
Active Phase 1
A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors
Advanced Solid Tumors
Bayer · started 2022-10-11
📍 Illinois · North Carolina · Texas · Utah
NCT05537740 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
Locally Advanced or Metastatic Solid Tumors, NSCLC, HNSCC, Melanoma
Genentech, Inc. · started 2022-10-20
📍 California · Colorado · Florida · Georgia · Massachusetts · Michigan · Missouri · New Jersey
NCT05581004 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors
Severe Hemophilia A
Hoffmann-La Roche · started 2021-02-04
📍 Arizona · California · Colorado · Louisiana · Michigan · Washington
NCT04431726 on ClinicalTrials.gov ↗
Recruiting Phase 2
Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Mixed Phenotype Acute Leukemia
Orca Biosystems, Inc. · started 2025-12-09
📍 California · Florida · New Jersey · New York · Oregon · Tennessee
NCT07216443 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC · started 2026-06-18
📍 Nebraska
NCT07554339 on ClinicalTrials.gov ↗
Recruiting Phase 2
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
Solid Tumours
Boehringer Ingelheim · started 2024-10-11
📍 Alaska · Arizona · California · Connecticut · Florida · Illinois · Indiana · Maryland
NCT06581432 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Diabetes Mellitus, Type 1
Eli Lilly and Company · started 2026-02-05
📍 Colorado · Florida · Pennsylvania · Texas · Virginia
NCT07222332 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Metabolic Dysfunction-Associated Steatotic Liver Disease
Eli Lilly and Company · started 2025-10-15
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia
NCT07165028 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome
Phelan-McDermid Syndrome
Neuren Pharmaceuticals Limited · started 2025-11-12
📍 California · Illinois · Maryland · Massachusetts · New York · Ohio · Texas
NCT07281079 on ClinicalTrials.gov ↗
Recruiting
FebriDx® Pediatric Validation Study
Acute Respiratory Infections (ARIs)
Lumos Diagnostics · started 2025-10-09
📍 California · Florida · Ohio · Pennsylvania · South Carolina · Texas
NCT07211997 on ClinicalTrials.gov ↗
Active Phase 3
Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer
Platinum-resistant Ovarian Cancer
Genmab · started 2025-02-07
📍 Alaska · Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii
NCT06619236 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Heart Failure, Heart Failure With Reduced Ejection Fraction
Cytokinetics · started 2024-12-19
📍 Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii
NCT06736574 on ClinicalTrials.gov ↗
Recruiting Phase 3
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Bipolar Depression
Intra-Cellular Therapies, Inc. · started 2024-05-14
📍 Alabama · Arkansas · California · Colorado · Florida · Georgia · Illinois · Indiana
NCT06372964 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Carcinoma, Non-Small-Cell Lung
Eli Lilly and Company · started 2025-03-27
📍 Alabama · Arizona · Arkansas · California · Connecticut · District of Columbia · Florida · Georgia
NCT06890598 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Brenipatide in Participants With Alcohol Use Disorder
Alcohol Use Disorder
Eli Lilly and Company · started 2025-10-16
📍 Arizona · Arkansas · California · Florida · Illinois · Maryland · Massachusetts · New York
NCT07219953 on ClinicalTrials.gov ↗
Recruiting Phase 1
Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity
Overweight or Obesity
Regeneron Pharmaceuticals · started 2026-06-29
📍 California
NCT07594093 on ClinicalTrials.gov ↗
Recruiting Phase 1
Phase 1 Trial of BTM-3566 in Relapsed/Refractory Mature B Cell Lymphomas
Lymphoma, B-Cell
Bantam Pharmaceuticals · started 2025-02-14
📍 North Carolina · Texas
NCT06792734 on ClinicalTrials.gov ↗
Recruiting Phase 3
Epidemiology and Biomarker Study in Alzheimer's Disease
Alzheimer Disease
Eli Lilly and Company · started 2025-08-25
📍 Texas
NCT07142954 on ClinicalTrials.gov ↗
Active Phase 1
A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours
Advanced Solid Tumor, Metastatic Colorectal Carcinoma, Head and Neck Squamous Cell Carcinoma, Non-small Cell Lung Cancer
AstraZeneca · started 2024-07-31
📍 California · Illinois · Nebraska · Ohio · Texas · Washington
NCT06147037 on ClinicalTrials.gov ↗
Active Phase 3
A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG)
Non-Muscle Invasive Bladder Neoplasms
Janssen Research & Development, LLC · started 2024-04-09
📍 Arkansas · California · Colorado · Florida · Illinois · Indiana · Kansas · Michigan
NCT06211764 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Durvalumab and Tremelimumab for Pediatric Malignancies
Pediatric Cancer, Solid Tumor Pediatric, Hematological Malignancies
AstraZeneca · started 2019-03-07
📍 Maryland · Massachusetts · New York · Oklahoma · South Carolina
NCT03837899 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
Early Breast Cancer
Novartis Pharmaceuticals · started 2024-02-28
📍 Alabama · Alaska · Arizona · Arkansas · California · Colorado · District of Columbia · Florida
NCT05827081 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease
Crohn Disease
Eli Lilly and Company · started 2026-05-04
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas · Michigan
NCT07483099 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase 1 Study of IM-1021 in Participants With Advanced Cancer
Solid Malignancies, Hematologic Malignancies
Immunome, Inc. · started 2025-02-26
📍 California · Colorado · Connecticut · Georgia · Iowa · Kentucky · Michigan · Nebraska
NCT06823167 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm
Eli Lilly and Company · started 2024-07-01
📍 California · Colorado · Florida · Illinois · Indiana · Massachusetts · Michigan · Missouri
NCT06465069 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis
Eli Lilly and Company · started 2025-12-12
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · District of Columbia · Florida
NCT07218380 on ClinicalTrials.gov ↗
Starting soon Phase 3
Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian Cancer
Platinum-Sensitive Ovarian Cancer, Ovarian Cancer
Genmab · started 2026-07
📍 Connecticut · Wisconsin
NCT07564141 on ClinicalTrials.gov ↗
Active
GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study
Abdominal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
W.L.Gore & Associates · started 2024-11-25
📍 California
NCT06578741 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine
Methamphetamine Intoxication, Methamphetamine Disorders, Methamphetamine Abuse
Clear Scientific, Inc. · started 2026-02-05
📍 California
NCT06721494 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Prostatic Neoplasms, Castration-Resistant
Janssen Research & Development, LLC · started 2018-03-02
📍 Arizona · Colorado · Florida · Indiana · Maryland · Michigan · New York · Pennsylvania
NCT03431350 on ClinicalTrials.gov ↗
Active Phase 2
A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
Prostatic Cancer, Castration-Resistant
Novartis Pharmaceuticals · started 2025-07-03
📍 California · Colorado · Connecticut · Indiana · Massachusetts · Nebraska · New York · Pennsylvania
NCT07047118 on ClinicalTrials.gov ↗
Recruiting
GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections
Aortic Dissection
W.L.Gore & Associates · started 2025-09-22
📍 Alabama · California · Florida · Georgia · Illinois · Indiana · Massachusetts · Michigan
NCT06827990 on ClinicalTrials.gov ↗
Active Phase 1
DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer
Small Cell Lung Carcinoma (SCLC)
Boehringer Ingelheim · started 2024-02-14
📍 Florida · Georgia
NCT06077500 on ClinicalTrials.gov ↗
Recruiting Phase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe
Eli Lilly and Company · started 2026-03-26
📍 Arizona · California · Colorado · Connecticut · Florida · Idaho · Illinois · Indiana
NCT07415044 on ClinicalTrials.gov ↗
Recruiting
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Coronary Artery Disease
Teleflex · started 2025-07-18
📍 California · Kansas · Massachusetts · Missouri · New York · Texas · West Virginia
NCT06779630 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Alzheimer Disease
Karuna Therapeutics, Inc., a Bristol Myers Squibb company · started 2024-09-26
📍 Arizona · California · Connecticut · Florida · Georgia · Massachusetts · Michigan · Mississippi
NCT06585787 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
Colitis, Ulcerative
Janssen Research & Development, LLC · started 2022-09-19
📍 California · Colorado · Connecticut · District of Columbia · Florida · Georgia · Idaho · Indiana
NCT05242484 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Inflammatory Bowel Diseases, Crohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) · started 2024-07-18
📍 California · Colorado · Florida · Georgia · Louisiana · Missouri · Nevada · North Carolina
NCT06226883 on ClinicalTrials.gov ↗
Recruiting Phase 1
First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
Advanced Solid Tumors, Breast Cancer Recurrent, Ovarian Cancer, High-grade Serous Ovarian Carcinoma
Accent Therapeutics · started 2025-03-21
📍 Florida · Michigan · Tennessee · Texas · Virginia
NCT06799065 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)
Diffuse Large B-Cell Lymphoma, Follicular Lymphoma
Genmab · started 2020-11-03
📍 Alabama · California · Massachusetts · Michigan · New Jersey · New York · North Carolina · Texas
NCT04663347 on ClinicalTrials.gov ↗
Recruiting
A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
Crohn Disease, Colitis, Ulcerative
Janssen Scientific Affairs, LLC · started 2021-06-24
📍 Texas
NCT04372108 on ClinicalTrials.gov ↗
Active
An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery
Unresectable Hepatocellular Carcinoma
Bayer · started 2023-11-27
📍 Maryland · Michigan · New York · Ohio · Pennsylvania
NCT06117891 on ClinicalTrials.gov ↗
Recruiting
Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array
Sensorineural Hearing Loss, Bilateral Hearing Loss
Cochlear · started 2025-05-05
📍 Colorado · Iowa · Ohio
NCT06936449 on ClinicalTrials.gov ↗
Recruiting Phase 3
Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT
Regional Citrate Anticoagulation (RCA), Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury (AKI)
Vantive Health LLC · started 2024-07-12
📍 Alabama · California · Florida · Georgia · Michigan · Ohio · Pennsylvania · South Carolina
NCT05399537 on ClinicalTrials.gov ↗
Recruiting Phase 3
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
Peripheral Arterial Disease
Eli Lilly and Company · started 2025-10-31
📍 Alabama · Arizona · California · Florida · Indiana · Maryland · Michigan · Pennsylvania
NCT07223593 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Obesity, Weight Gain
Eli Lilly and Company · started 2024-06-03
📍 California · Delaware · Idaho · Illinois · Indiana · New York · Texas · Utah
NCT06439277 on ClinicalTrials.gov ↗
Recruiting
AERA Pediatrics Registry
Dysfunction of Eustachian Tube
Integra LifeSciences Corporation · started 2025-06-17
📍 California · Massachusetts · Michigan · Minnesota · Ohio · Pennsylvania · Texas · Utah
NCT07071298 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Multiple Sclerosis (MS) Primary Progressive
Zenas BioPharma (USA), LLC · started 2026-03-23
📍 Arizona · California · Florida · Kansas · Missouri · North Carolina · Ohio · South Carolina
NCT07067463 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Hoffmann-La Roche · started 2025-10-24
📍 Alaska · Arizona · California · Colorado · Connecticut · Florida · Georgia · Idaho
NCT06793215 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Sleep Apnea, Obstructive, Obesity, Overweight
Eli Lilly and Company · started 2026-02-10
📍 Alabama · California · Colorado · Florida · Georgia · Louisiana · Maryland · Michigan
NCT07369011 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide in Adult Participants With Schizophrenia
Schizophrenia
Eli Lilly and Company · started 2026-02-10
📍 Arkansas · California · Connecticut · Florida · Georgia · Illinois · Maryland · Massachusetts
NCT07410507 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)
Immunoglobulin A Nephropathy (IgAN)
Biogen · started 2025-05-08
📍 Arkansas · California · Florida · Georgia · Massachusetts · Michigan · Mississippi · Missouri
NCT06935357 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Diabetes Mellitus, Type 1
Eli Lilly and Company · started 2026-01-12
📍 Florida · Iowa · Kentucky · Pennsylvania · Virginia
NCT07222137 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Neoplasm Metastasis
Eli Lilly and Company · started 2025-10-22
📍 Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii
NCT07213804 on ClinicalTrials.gov ↗
Active Phase 1
A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
HIV Infections
ViiV Healthcare · started 2025-07-10
📍 California · Florida · Illinois · Missouri · New York · Ohio · Pennsylvania · Texas
NCT07053384 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Multiple Myeloma
AbbVie · started 2025-07-23
📍 California · Connecticut · Massachusetts · Michigan · New York · North Carolina · Oregon · Texas
NCT06953960 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
Colorectal Cancer
Takeda · started 2025-01-14
📍 Alabama · Arizona · California · Delaware · Florida · Georgia · Illinois · Indiana
NCT06562543 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
LMNA-Related Dilated Cardiomyopathy
Nuevocor Pte. Ltd. · started 2026-06-16
📍 Alabama · California · Massachusetts · Minnesota · Ohio · Texas
NCT07606274 on ClinicalTrials.gov ↗
Starting soon Phase 3
Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)
Vanda Pharmaceuticals · started 2026-09
📍 California · Tennessee
NCT07686081 on ClinicalTrials.gov ↗
Recruiting
Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis
Rheumatoid Arthritis
Surf Therapeutics · started 2026-03-20
📍 Texas
NCT07293871 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
Nausea, Vomiting, Drug-Related Side Effects and Adverse Reactions, Neoplasms
Eli Lilly and Company · started 2025-11-28
📍 California · Colorado · Florida · Georgia · Illinois · Indiana · Mississippi · New York
NCT07169851 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Breast Neoplasms, Neoplasm Metastasis
Eli Lilly and Company · started 2025-12-22
📍 Alaska · Arizona · Arkansas · California · Colorado · District of Columbia · Florida · Georgia
NCT07174336 on ClinicalTrials.gov ↗
Recruiting Phase 2
To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
Breast Cancer
Hoffmann-La Roche · started 2026-02-18
📍 California · New Jersey
NCT07368998 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors
Solid Tumors, Adult
Hutchmed · started 2025-12-16
📍 Colorado · Florida · New Jersey · New York · Ohio · Washington
NCT07228247 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
Obesity, Overweight, Diabetes Mellitus, Type 2
Eli Lilly and Company · started 2025-10-16
📍 Arizona · Florida · Georgia · Nevada · New Jersey · Ohio · Texas · Utah
NCT07215559 on ClinicalTrials.gov ↗
Recruiting Phase 3
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
Glioblastoma, Recurrent Glioblastoma, GBM
CarThera · started 2024-01-29
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana · Maryland
NCT05902169 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome, Treatment-naïve High Risk Chronic Lymphocytic Leukemia
Genmab · started 2020-11-25
📍 Alabama · California · Florida · Maryland · Massachusetts · Michigan · New Jersey · New York
NCT04623541 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Asthma
Eli Lilly and Company · started 2025-10-22
📍 Arizona · California · Colorado · Florida · Illinois · Kentucky · Massachusetts · Nevada
NCT07219173 on ClinicalTrials.gov ↗
Active Phase 3
Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer
Cancer
Bayer · started 2020-10-20
📍 Alabama · Arizona · California · Colorado · Florida · Illinois · Kentucky · Maryland
NCT04464226 on ClinicalTrials.gov ↗
Active Phase 3
Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients
Advanced Ovarian Cancer
AstraZeneca · started 2019-01-04
📍 California · Florida · Georgia · Illinois · Indiana · Maryland · Michigan · Missouri
NCT03737643 on ClinicalTrials.gov ↗
Active Phase 4
A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP) Who Need Treatment for Repeated Flares
Generalized Pustular Psoriasis
Boehringer Ingelheim · started 2023-10-22
📍 California · North Dakota
NCT06013969 on ClinicalTrials.gov ↗
Recruiting Phase 3
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Ulcerative Colitis, Obesity or Overweight
Eli Lilly and Company · started 2025-06-26
📍 Alabama · California · Florida · Idaho · Illinois · Indiana · Kentucky · Louisiana
NCT06937086 on ClinicalTrials.gov ↗
Starting soon Phase 3
DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy
Extrapulmonary Neuroendocrine Cancer
Boehringer Ingelheim · started 2026-07-07
📍 Arizona · California · Florida · Georgia · Maryland · Massachusetts · Minnesota · Missouri
NCT07544654 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study of ZL-1310 in Participants With Selected Solid Tumors
Solid Tumors
Zai Lab (Shanghai) Co., Ltd. · started 2025-05-12
📍 California · Illinois · Michigan · New York · Ohio · Pennsylvania · Tennessee · Texas
NCT06885281 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Pancreatic Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma (PDAC)
Revolution Medicines, Inc. · started 2025-12-15
📍 California · Colorado · Connecticut · Florida · Georgia · Indiana · Kansas · Maryland
NCT07252232 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Obesity, Overweight
Eli Lilly and Company · started 2026-02-06
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Hawaii · Iowa
NCT07321886 on ClinicalTrials.gov ↗
Starting soon Phase 1/Phase 2
First-in-Human Trial of VBC106 in Participants With Advanced Solid Tumors
Participants With Advanced Solid Tumor Malignancies
VelaVigo Bio Inc · started 2026-08-18
📍 Texas · Utah · Virginia
NCT07686068 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
Urothelial Cancer
Bristol-Myers Squibb · started 2025-09-30
📍 Arizona · California · Colorado · District of Columbia · Florida · Kentucky · Maryland · Massachusetts
NCT07106762 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Microdystrophin Gene Transfer Study in Adolescents and Children With DMD
Duchenne Muscular Dystrophy
Solid Biosciences Inc. · started 2017-12-06
📍 California · Florida
NCT03368742 on ClinicalTrials.gov ↗
Recruiting Phase 3
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
Plaque Psoriasis
Bristol-Myers Squibb · started 2025-09-22
📍 Alabama · Arizona · Arkansas · California · Colorado · District of Columbia · Florida · Georgia
NCT07116967 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Endometrial Cancer
Merck Sharp & Dohme LLC · started 2025-05-22
📍 Alabama · Alaska · California · Connecticut · District of Columbia · Florida · Georgia · Illinois
NCT06952504 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
Adenocarcinoma, Pancreatic Ductal
Genentech, Inc. · started 2023-10-18
📍 California · Connecticut · Illinois · Indiana · Kentucky · Massachusetts · Michigan · Nebraska
NCT05968326 on ClinicalTrials.gov ↗
Recruiting Phase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Alzheimers Disease
Hoffmann-La Roche · started 2025-07-02
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Hawaii · Illinois
NCT07177352 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors
ALK Fusion-positive Solid or CNS Tumors
Hoffmann-La Roche · started 2021-09-14
📍 California · Florida · Michigan · Minnesota · New York · Ohio · Tennessee
NCT04774718 on ClinicalTrials.gov ↗
Active Phase 2
An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Tisento Therapeutics · started 2025-08-18
📍 California · Colorado · Georgia · Massachusetts · New York · Ohio · Pennsylvania · Texas
NCT06961344 on ClinicalTrials.gov ↗
Recruiting Phase 3
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Crohn's Disease, Obesity or Overweight
Eli Lilly and Company · started 2025-06-26
📍 Alabama · California · Florida · Idaho · Illinois · Indiana · Kentucky · Louisiana
NCT06937099 on ClinicalTrials.gov ↗
Active Phase 2
A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS)
Novartis Pharmaceuticals · started 2024-10-17
📍 California · Florida · Georgia · Kansas · Massachusetts · Nebraska · New York · North Carolina
NCT06643481 on ClinicalTrials.gov ↗
Recruiting
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
Parkinson's Disease
Boston Scientific Corporation · started 2014-03-04
📍 California · Colorado · Florida · Idaho · Illinois · Indiana · Massachusetts · Missouri
NCT02071134 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain
Diabetic Peripheral Neuropathic Pain
Eli Lilly and Company · started 2026-02-16
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Illinois · Louisiana
NCT07285018 on ClinicalTrials.gov ↗
Recruiting Phase 3
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy
Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Boehringer Ingelheim · started 2026-04-13
📍 Alabama · Arkansas · Florida · Georgia · Kentucky · Louisiana · Maryland · Michigan
NCT07472517 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Endometrial Cancer, Recurrent or Progressive Endometrial Cancer
Genmab · started 2025-11-28
📍 Arizona · California · District of Columbia · Florida · Georgia · Louisiana · Maryland · Michigan
NCT07166094 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Depressive Disorder, Major
Eli Lilly and Company · started 2026-02-09
📍 California · Connecticut · Florida · Georgia · Indiana · Iowa · Maryland · Massachusetts
NCT07412756 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234
Hepatic Impairment
AstraZeneca · started 2026-03-20
📍 Arizona · California · Florida · Texas
NCT07546760 on ClinicalTrials.gov ↗
Active Phase 3
A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy
Primary Membranous Nephropathy
Hoffmann-La Roche · started 2021-06-25
📍 California · Colorado · Florida · Iowa · Michigan · Minnesota · New York · Texas
NCT04629248 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma
DLBCL, High-grade B-cell Lymphoma (HGBCL), Primary Mediastinal Large B-cell Lymphoma (PMBCL), FL
Genmab · started 2018-06-26
📍 Arizona · California · Colorado · Florida · Iowa · Louisiana · Michigan · Nebraska
NCT03625037 on ClinicalTrials.gov ↗
Active Phase 3
Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)
PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC
Genmab · started 2024-11-25
📍 Arizona · California · Florida · Georgia · Hawaii · Illinois · Indiana · Kentucky
NCT06635824 on ClinicalTrials.gov ↗
Recruiting Phase 3
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
Irritability Associated With Autism Spectrum Disorder
Intra-Cellular Therapies, Inc. · started 2024-11-22
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Massachusetts
NCT06690398 on ClinicalTrials.gov ↗
Recruiting Phase 2
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
Type 1 Diabetes Mellitus
Mannkind Corporation · started 2026-02-04
📍 California · Colorado · Connecticut · Florida · Indiana · Massachusetts · Oklahoma · Texas
NCT07224321 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Eli Lilly and Company · started 2024-04-29
📍 Alabama · Arizona · California · Colorado · Florida · Idaho · Illinois · Kansas
NCT06338995 on ClinicalTrials.gov ↗
Recruiting Phase 2
Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma
Low Grade Upper Tract Urothelial Carcinoma
Tyra Biosciences, Inc · started 2025-12-22
📍 Georgia · Illinois · Indiana · Massachusetts · New Jersey · New York · Ohio · Tennessee
NCT07265947 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide in Participants With Opioid Use Disorder
Opioid Use Disorder
Eli Lilly and Company · started 2026-02-13
📍 Arizona · Arkansas · California · Florida · Illinois · Indiana · Kentucky · Maryland
NCT07420283 on ClinicalTrials.gov ↗
Recruiting Phase 1
First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
Advanced Metastatic Castration-resistant Prostate Cancer, Prostate Specific Membrane Antigen (PSMA) Expression
Bayer · started 2024-03-07
📍 California · Minnesota · Nebraska · Texas
NCT06217822 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Advanced Solid Malignancies
AstraZeneca · started 2022-06-24
📍 California · Illinois · Massachusetts · New York · Oregon · Texas · Virginia
NCT05417594 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors
Advanced Solid Tumors
CStone Pharmaceuticals · started 2025-02-24
📍 California · Texas
NCT06741644 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation
Microvascular Inflammation
Biogen · started 2026-01-05
📍 California · Kansas · Michigan · Minnesota · Missouri · Nebraska · New Jersey · North Carolina
NCT07219043 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
Colitis, Ulcerative, Crohn Disease
Eli Lilly and Company · started 2026-05-04
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas · Michigan
NCT07483073 on ClinicalTrials.gov ↗
Active Phase 3
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
Heart Failure
Novo Nordisk A/S · started 2023-05-08
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia
NCT05636176 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma
Non-Hodgkin Lymphoma
Genmab · started 2022-06-14
📍 Arizona · Connecticut · Delaware · Florida · Georgia · Maryland · Missouri · New York
NCT05283720 on ClinicalTrials.gov ↗
Recruiting Phase 2
Confirmatory Clinical Study in Active Ulcerative Colitis
Colitis, Ulcerative
MRM Health NV · started 2026-04-03
📍 Florida · North Carolina · Texas
NCT07296315 on ClinicalTrials.gov ↗
Recruiting Phase 3
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients
Irritability Associated With Autism Spectrum Disorder
Intra-Cellular Therapies, Inc. · started 2024-12-06
📍 Arkansas · California · Connecticut · Florida · Georgia · Illinois · Indiana · Louisiana
NCT06706674 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma
Moderate to Severe Asthma
Incyte Corporation · started 2023-07-11
📍 Alabama · California · Florida · Georgia · Illinois · Michigan · New York · North Carolina
NCT05851443 on ClinicalTrials.gov ↗
Active Phase 3
A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Diffuse Large B-cell Lymphoma
Hoffmann-La Roche · started 2021-02-23
📍 Alabama · California · Florida · Maryland · Massachusetts · Mississippi · New Jersey · New York
NCT04408638 on ClinicalTrials.gov ↗
Active Phase 2
Study of Neoadjuvant Olaparib Monotherapy and Olaparib and Durvalumab Combination in HER2 Negative BRCAm Breast Cancer
Breast Cancer
AstraZeneca · started 2022-11-07
📍 Colorado · Massachusetts · Oregon · Pennsylvania
NCT05498155 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Hemophilia A
Hoffmann-La Roche · started 2026-04-27
📍 California · Indiana · Iowa · Washington
NCT07416604 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
Colorectal Cancer
AbbVie · started 2026-05-22
📍 New Jersey · Washington
NCT07525206 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) and Placebo Given With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies
Biochemically Recurrent Prostate Cancer
Bayer · started 2023-04-03
📍 Arizona · California · Colorado · Illinois · Maryland · Massachusetts · Michigan · Minnesota
NCT05794906 on ClinicalTrials.gov ↗
Recruiting Phase 1
Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib
Healthy, Hepatic Impairment
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany · started 2025-05-07
📍 Florida · Texas
NCT06997276 on ClinicalTrials.gov ↗
Recruiting Phase 1
Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors
Advanced Solid Tumors
Genmab · started 2026-04-07
📍 Connecticut · Michigan · New York
NCT07387068 on ClinicalTrials.gov ↗
Recruiting Phase 3
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder
Intra-Cellular Therapies, Inc. · started 2024-01-25
📍 Arizona · Arkansas · California · Colorado · Florida · Georgia · Illinois · Indiana
NCT06229210 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis
Atopic Dermatitis
LEO Pharma · started 2024-06-10
📍 Alabama · Arkansas · California · Florida · Georgia · Michigan · Oklahoma · Oregon
NCT06311682 on ClinicalTrials.gov ↗
Active Phase 1
DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers
Neuroendocrine Neoplasms
Boehringer Ingelheim · started 2024-01-22
📍 Florida · Georgia · Illinois · New Jersey · Pennsylvania
NCT06132113 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)
Chronic Hepatitis B Virus Infection, Hepatitis B
GlaxoSmithKline · started 2024-11-11
📍 California · Minnesota · New York · Pennsylvania
NCT06537414 on ClinicalTrials.gov ↗
Active Phase 3
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Plaque Psoriasis
Janssen Research & Development, LLC · started 2024-02-01
📍 Arizona · Arkansas · California · Florida · Georgia · Illinois · Indiana · Kentucky
NCT06143878 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency
Growth Hormone Deficiency (GHD)
Lumos Pharma · started 2026-05-20
📍 Alabama · California · Colorado · District of Columbia · Florida · Indiana · Iowa · Louisiana
NCT06948214 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of JADE101 in Participants With Immunoglobulin A Nephropathy
IgA Nephropathy
Jade Biosciences, Inc. · started 2026-05-19
📍 California · Colorado · Florida · Texas
NCT07541287 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis
Atopic Dermatitis
Hoffmann-La Roche · started 2026-01-08
📍 Georgia · Michigan · Pennsylvania
NCT07223697 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
Irritable Bowel Syndrome, Constipation
Eli Lilly and Company · started 2026-04-29
📍 Arizona · California · Florida · Illinois · Indiana · Kentucky · New York · Ohio
NCT07545772 on ClinicalTrials.gov ↗
Recruiting
A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.
Ankle Arthrodesis or Arthroplasty, Hindfoot Fusion, Ankle Deformity, Ankle Disease
Kuros Biosurgery AG · started 2025-11-25
📍 Colorado · Georgia · North Carolina · Pennsylvania · Tennessee · Virginia
NCT07225751 on ClinicalTrials.gov ↗
Active Phase 1
A First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid Tumors
Advanced Solid Tumors
Bayer · started 2022-11-04
📍 Colorado · Pennsylvania · Texas
NCT05614102 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
Biliary Tract Cancer
AstraZeneca · started 2024-08-12
📍 Arizona · California · District of Columbia · Florida · Georgia · Idaho · Illinois · Maryland
NCT06467357 on ClinicalTrials.gov ↗
Starting soon Phase 3
A Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline)
Gastrointestinal Stromal Neoplasms
GlaxoSmithKline · started 2026-07-10
📍 Ohio
NCT07585266 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Alzheimer Disease, Dementia, Plaque, Amyloid
Eli Lilly and Company · started 2026-05-22
📍 Arizona · California · Florida · Georgia · Idaho · Illinois · Indiana · Iowa
NCT07602582 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)
Rett Syndrome
Taysha Gene Therapies, Inc. · started 2023-03-06
📍 California · Illinois · Maryland · Massachusetts · Missouri · Texas
NCT05606614 on ClinicalTrials.gov ↗
Active Phase 1
A Study to Test How Well BI 3000202 is Tolerated by People With Type 1 Interferonopathies
Type 1 Interferonopathies
Boehringer Ingelheim · started 2025-07-29
📍 California · Pennsylvania · Texas
NCT06878365 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
Follicular Lymphoma (FL)
Genmab · started 2024-02-05
📍 California · Colorado · Delaware · Florida · Idaho · Illinois · Indiana · Iowa
NCT06191744 on ClinicalTrials.gov ↗
Active Phase 3
ABTECT - Maintenance
Ulcerative Colitis
Abivax S.A. · started 2023-01-16
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia
NCT05535946 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
Osteoarthritis
Eli Lilly and Company · started 2025-09-15
📍 Arizona · California · Colorado · Connecticut · Georgia · Illinois · Kansas · Massachusetts
NCT07153471 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Overweight, Obesity
Eli Lilly and Company · started 2025-12-15
📍 Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii
NCT07282600 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Overweight, Obesity
Eli Lilly and Company · started 2026-02-10
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Idaho · Illinois
NCT07392190 on ClinicalTrials.gov ↗
Starting soon
Measuring Knee Laxity and Pivot Shift in ACL-Deficient Patients
Anterior Cruciate Ligament (ACL) Tear
Arthroresearch LLC · started 2026-07-07
📍 Georgia
NCT07688967 on ClinicalTrials.gov ↗
Starting soon Phase 3
Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia
Schizophrenia
Karuna Therapeutics, Inc., a Bristol Myers Squibb company · started 2026-09-03
📍 Arkansas · California · Florida · Georgia · Illinois · Missouri · New York · Ohio
NCT07686263 on ClinicalTrials.gov ↗
Recruiting Phase 1
A First in Human Study of PLT012 in Participants With Solid Tumor Cancers
Advanced Malignant Solid Tumor, Solid Tumor Cancer
Pilatus Biosciences Inc · started 2026-02-13
📍 California · Texas
NCT07337525 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Hidradenitis Suppurativa
Eli Lilly and Company · started 2023-10-23
📍 Arizona · Arkansas · California · Connecticut · Florida · Georgia · Illinois · Indiana
NCT06046729 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
Melanoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma (Skin), Renal Cell Carcinoma
AstraZeneca · started 2025-07-29
📍 Michigan · Missouri · Pennsylvania · Texas · Virginia
NCT07115043 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes
Type 2 Diabetes Mellitus
Hoffmann-La Roche · started 2025-08-19
📍 Arizona · California · Connecticut · District of Columbia · Florida · Georgia · Illinois · Montana
NCT07112872 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Eli Lilly and Company · started 2023-12-21
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · District of Columbia · Florida
NCT06119581 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Obesity, Overweight
Eli Lilly and Company · started 2023-11-17
📍 Arizona · California · Connecticut · Florida · Hawaii · Idaho · Illinois · Iowa
NCT06143956 on ClinicalTrials.gov ↗
Recruiting
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body
Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Bayer · started 2020-04-03
📍 Arizona · California · Colorado · Connecticut · Florida · Indiana · Kansas · Maine
NCT04142437 on ClinicalTrials.gov ↗
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Cite this page

Priya Life Science (2026). Clinical Trials in the USA Tracker. Available at: https://priyalifescience.com/clinical-trials-usa (Accessed: 8 July 2026).

Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one US site, most recently updated first, refreshed daily. This is a curated slice of the full registry, not every US trial. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish and EU sites, see our Ireland and EU trackers.