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Updated 06 Sep 2026 · ClinicalTrials.gov

Clinical Trials in the USA

The most recently updated industry-sponsored clinical trials recruiting across the United States — searchable by condition, sponsor, phase and state. Refreshed daily from the ClinicalTrials.gov registry.

118
Recruiting now
160
Studies tracked
44
States with sites
Recruiting Phase 1
A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC)
Metastatic Colorectal Cancer
Hoffmann-La Roche · started 2026-09-08
Nebraska · Texas · Wisconsin
NCT07416552 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
Psychosis Associated With Alzheimer's Disease
Karuna Therapeutics, Inc., a Bristol Myers Squibb company · started 2023-08-28
Arizona · California · Florida · Georgia · Illinois · Louisiana · Michigan · Mississippi
NCT06126224 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to-Severe Eczema
Atopic Dermatitis
Pfizer · started 2026-08-17
California · Florida
NCT07765888 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors
Advanced Solid Tumor, Adult, ERBB2 Altered Breast Cancer, ERBB2 Gene Amplification, HER2 Overexpression
Cogent Biosciences, Inc. · started 2025-12-30
Arizona · Connecticut · Florida · Illinois · Louisiana · Michigan · Minnesota · Missouri
NCT07361562 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib
Hepatic Impairment
Genentech, Inc. · started 2025-08-21
California · Florida · Texas
NCT07144111 on ClinicalTrials.gov ↗
By invitation
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
Truway Health, Inc. · started 2026-08-31
New York
NCT07805044 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Obesity, Weight Gain
Eli Lilly and Company · started 2024-06-03
California · Delaware · Idaho · Illinois · Indiana · New York · Texas · Utah
NCT06439277 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy)
Grifols Therapeutics LLC · started 2026-04-02
California · Florida · New York · Tennessee · Texas
NCT07540221 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Hemophilia A
Hoffmann-La Roche · started 2026-04-27
California · Colorado · Florida · Indiana · Iowa · Washington
NCT07416604 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
Primary Prevention of Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals · started 2023-03-09
Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii
NCT05739383 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
Non-small Cell Lung Cancer
BioNTech SE · started 2025-01-07
Alabama · Alaska · California · Florida · Indiana · Iowa · Kentucky · Maryland
NCT06712316 on ClinicalTrials.gov ↗
Recruiting Phase 4
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
Cervical Cancer
Pfizer · started 2025-05-07
Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana · Kentucky
NCT06952660 on ClinicalTrials.gov ↗
Recruiting Phase 3
Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial
Hypereosinophilic Syndrome
GlaxoSmithKline · started 2022-09-06
California · Georgia · Massachusetts · Michigan · Minnesota · New York · Ohio · South Carolina
NCT05334368 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema
Atopic Dermatitis, Eczema, Atopic
Pfizer · started 2025-11-20
Arizona · California · Florida · New York · Pennsylvania
NCT07216027 on ClinicalTrials.gov ↗
Active Phase 2
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
Solid Tumors
Hoffmann-La Roche · started 2021-01-18
Arizona · California · Georgia · Idaho · Illinois · Indiana · Maryland · Michigan
NCT04589845 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.
Follicular Lymphoma, Marginal Zone Lymphoma
Incyte Corporation · started 2021-04-15
California · Connecticut · Florida · Georgia · Hawaii · Iowa · Kentucky · Louisiana
NCT04680052 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis
CKD, Metabolic Acidosis
Renibus Therapeutics, Inc. · started 2026-01-13
California · Colorado · Florida · Georgia · Idaho · Illinois · Indiana · Kentucky
NCT07355062 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL
Diffuse Large B-Cell Lymphoma
AstraZeneca · started 2024-07-16
California · Connecticut · Florida · Iowa · Kentucky · Maryland · Michigan · South Dakota
NCT05952024 on ClinicalTrials.gov ↗
Recruiting Phase 1
An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancers
Advanced Malignancies, Advanced Cancer
Pfizer · started 2026-07-01
Florida · Georgia · Tennessee
NCT07426757 on ClinicalTrials.gov ↗
Recruiting
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Lumbar Spinal Stenosis
Stryker Instruments · started 2017-03-10
Alabama · Alaska · Arizona · Arkansas · California · Colorado · Connecticut · Delaware
NCT03072927 on ClinicalTrials.gov ↗
Recruiting Phase 3
An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS
Hidradenitis Suppurativa
Novartis Pharmaceuticals · started 2026-07-10
Arkansas · California · Illinois · Indiana · Nebraska · New York · Ohio · South Carolina
NCT07665437 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
Breast Cancer
Novartis Pharmaceuticals · started 2024-08-14
California · Minnesota · Texas · Wisconsin
NCT06247995 on ClinicalTrials.gov ↗
Recruiting Phase 1
Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS
Relapsed Acute Myeloid Leukemia (AML), Refractory Acute Myeloid Leukemia (AML), Relapsed/Refractory AML, Relapsed Myelodysplastic Syndromes
Auron Therapeutics, Inc. · started 2025-05-01
California · Florida · New York · North Carolina · Ohio · Pennsylvania · Tennessee · Texas
NCT06846606 on ClinicalTrials.gov ↗
Recruiting Phase 3
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
Diabetes Mellitus, Overweight, Obesity
Novo Nordisk A/S · started 2026-04-13
Alabama · California · Florida · Minnesota · New York · South Carolina · Tennessee · Texas
NCT07533175 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations
Advanced Solid Tumors With MAPK Pathway Mutations
D3 Bio (Wuxi) Co., Ltd · started 2023-07-10
Michigan · New York · Tennessee · Texas
NCT05886920 on ClinicalTrials.gov ↗
Recruiting Phase 2
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease
Graves' Disease
Yarrow Bioscience, Inc. · started 2026-06-10
Arizona · California · Florida · Georgia · Kentucky · Michigan · Nebraska · New York
NCT07682896 on ClinicalTrials.gov ↗
Recruiting Phase 1
Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function
Healthy Participants, Hepatic Impairment
Arcus Biosciences, Inc. · started 2026-08-14
Texas
NCT07751250 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
Alcohol Use Disorder
Eli Lilly and Company · started 2025-10-15
Alabama · Arizona · Arkansas · California · Colorado · Florida · Illinois · Maryland
NCT07219966 on ClinicalTrials.gov ↗
Starting soon Phase 2
A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
PARKINSON DISEASE (Disorder)
Vima Therapeutics · started 2026-09
Arizona · California · Connecticut · Florida · Georgia · Kansas · Maryland · Michigan
NCT07804615 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
Degenerative Disc Disease
DiscGenics, Inc. · started 2025-12-23
Alabama · Arizona · California · District of Columbia · Florida · Idaho · Indiana · Kentucky
NCT07254806 on ClinicalTrials.gov ↗
Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Heart Failure - NYHA II - IV
Boston Scientific Corporation · started 2025-10-22
Alabama · Arizona · Arkansas · California · District of Columbia · Florida · Georgia · Illinois
NCT07069738 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Verastem, Inc. · started 2026-07-22
California · Georgia · New Jersey · New York · Texas · Virginia
NCT07659782 on ClinicalTrials.gov ↗
Recruiting Phase 1
R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors
Solid Tumor, Adult, Solid Tumor, Melanoma, Basal Cell Cancer
Rise Therapeutics LLC · started 2025-08-01
Colorado · Tennessee
NCT06398418 on ClinicalTrials.gov ↗
Active Phase 3
Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC
Prostate Cancer
Pfizer · started 2021-05-12
Alabama · Arizona · California · Connecticut · District of Columbia · Florida · Georgia · Illinois
NCT04821622 on ClinicalTrials.gov ↗
By invitation Phase 3
An Evaluation of the Long-Term Safety and Efficacy of TSND-201 for the Treatment of PTSD
Post Traumatic Stress Disorder
Transcend Therapeutics · started 2026-06-22
Arkansas · California · Colorado · Florida · Massachusetts · Missouri · New Jersey · Ohio
NCT07670702 on ClinicalTrials.gov ↗
Recruiting Phase 2
An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis
Plaque Psoriasis
Oruka Therapeutics, Inc. · started 2026-02-23
Arizona · California · Connecticut · Florida · Illinois · Kentucky · Maryland · Massachusetts
NCT07449702 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide in Adult Participants With Schizophrenia
Schizophrenia
Eli Lilly and Company · started 2026-02-10
Arkansas · California · Connecticut · Florida · Georgia · Illinois · Maryland · Massachusetts
NCT07410507 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Advanced/Metastatic Solid Tumors, Bladder Cancer, Urothelial Carcinoma, Advanced Non-Small Cell Lung Cancer
Pfizer · started 2025-08-20
California · Connecticut · Massachusetts · Tennessee · Texas
NCT07090499 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)
Hereditary Angioedema (HAE), Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2, HAE
ADARx Pharmaceuticals, Inc. · started 2026-04-02
Arizona · Arkansas · California · Florida · Maryland · Michigan · Missouri · Nevada
NCT07428499 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients
Hypertension
Novartis Pharmaceuticals · started 2025-03-26
Alabama · Arizona · California · Florida · Georgia · Idaho · Illinois · Indiana
NCT06857955 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
Novartis Pharmaceuticals · started 2025-04-22
California · North Carolina · Pennsylvania · Texas
NCT06704269 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
Moderate to Severe Glabellar Lines
Ipsen · started 2026-02-18
California · Connecticut · District of Columbia · Florida · Georgia · Illinois · Indiana · Louisiana
NCT07435428 on ClinicalTrials.gov ↗
Recruiting Phase 3
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma
Immuneering Corporation · started 2026-06-05
Alabama · Arizona · California · Colorado · Delaware · Florida · Georgia · Illinois
NCT07562152 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old
Graves' Disease
Biogen · started 2026-07-30
Arizona · California · Florida · North Carolina · Texas
NCT07722546 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
Nausea, Vomiting, Drug-Related Side Effects and Adverse Reactions, Neoplasms
Eli Lilly and Company · started 2025-11-28
California · Colorado · Florida · Georgia · Illinois · Indiana · Mississippi · New York
NCT07169851 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Learn About the Single Dose Pharmacokinetics of Study Medicine Called Tilrekimig in Healthy Adults When Co-Mixed With rHuPH20
Healthy
Pfizer · started 2026-08-27
Connecticut
NCT07792941 on ClinicalTrials.gov ↗
Recruiting
Patient Retrospective Outcomes (PRO)
Chronic Pain
Boston Scientific Corporation · started 2012-04-03
Arizona · California · Colorado · Connecticut · Florida · Georgia · Hawaii · Idaho
NCT01550575 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Diabetes Mellitus, Type 1
Eli Lilly and Company · started 2026-01-12
California · Florida · Iowa · Kentucky · Pennsylvania · Virginia
NCT07222137 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide in Participants With Opioid Use Disorder
Opioid Use Disorder
Eli Lilly and Company · started 2026-02-13
Arizona · Arkansas · California · Florida · Illinois · Indiana · Kentucky · Maryland
NCT07420283 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Study of IMGN632 in Patients With Untreated BPDCN and Relapsed/Refractory BPDCN
Blastic Plasmacytoid Dendritic Cell Neoplasm, Myeloproliferative Neoplasm
AbbVie · started 2018-01-02
Alabama · Arizona · California · Florida · Maryland · Massachusetts · New York · North Carolina
NCT03386513 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy
Relapsed or Refractory Large B-cell Lymphoma
Kite, A Gilead Company · started 2026-05-22
Arizona · California · Colorado · Connecticut · Florida · Georgia · Illinois · Missouri
NCT07479797 on ClinicalTrials.gov ↗
Recruiting
CoMind Early Feasibility Study
Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage
CoMind Technologies Limited · started 2024-11-27
California · Delaware · District of Columbia · Florida · Iowa · Kansas · Missouri · New York
NCT06368648 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Inflammatory Bowel Diseases, Crohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) · started 2024-07-18
California · Colorado · Florida · Georgia · Louisiana · Missouri · Nevada · North Carolina
NCT06226883 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema
Atopic Dermatitis
Pfizer · started 2025-12-02
Alabama · Arkansas · California · Florida · Idaho · Indiana · Missouri · South Carolina
NCT06807281 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
Ovarian Neoplasms, Endometrial Neoplasms, Uterine Cervical Neoplasms, Carcinoma, Non-Small-Cell Lung
Eli Lilly and Company · started 2024-05-20
Arizona · California · Georgia · Michigan · New York · Ohio · Texas · Utah
NCT06400472 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension
Insmed Incorporated · started 2026-07-21
California · New York · Pennsylvania · South Carolina
NCT07481981 on ClinicalTrials.gov ↗
Recruiting Phase 1
Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer
Advanced HR+/HER2- Breast Cancer
Novartis Pharmaceuticals · started 2026-05-28
Connecticut · Texas
NCT07604571 on ClinicalTrials.gov ↗
Recruiting Phase 2
To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer
Breast Cancer
Hoffmann-La Roche · started 2026-02-18
California · Florida · Missouri · New Jersey
NCT07368998 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
Melanoma (Skin Cancer), HER2-low Hormone Receptor Positive Breast Cancer
Aminex Therapeutics, Inc. · started 2026-01-26
Arizona · California · Colorado · Kansas · Michigan · Minnesota · New York · Ohio
NCT07287917 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
Solid Tumors
ORIC Pharmaceuticals · started 2022-03-10
California · Connecticut · District of Columbia · Florida · Illinois · Massachusetts · Minnesota · New York
NCT05315700 on ClinicalTrials.gov ↗
By invitation Phase 3
A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
UCB Biopharma SRL · started 2021-07-27
Alabama · Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois
NCT04976322 on ClinicalTrials.gov ↗
Recruiting
WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment)
Stroke, Acute
Philips Clinical & Medical Affairs Global · started 2021-06-23
Florida · Georgia · New York
NCT04701684 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults
Chronic Migraine
Ipsen · started 2023-10-12
Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Illinois
NCT06047444 on ClinicalTrials.gov ↗
Active
A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development
Spasticity as Sequela of Stroke
Ipsen · started 2023-11-01
California · Florida · Maryland · Massachusetts · Missouri · Nebraska · Nevada · North Carolina
NCT06055725 on ClinicalTrials.gov ↗
Recruiting Phase 3
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Crohn's Disease, Obesity or Overweight
Eli Lilly and Company · started 2025-06-26
Alabama · California · Florida · Idaho · Illinois · Indiana · Kentucky · Louisiana
NCT06937099 on ClinicalTrials.gov ↗
Recruiting
A Prospective Research Investigation of Ischemia Using MCG
Acute Coronary Syndrome
SB Technology, Inc. · started 2024-07-11
Minnesota · New York
NCT06481943 on ClinicalTrials.gov ↗
Recruiting Phase 1
Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors
Solid Tumor
ImmunoGenesis · started 2023-09-07
Arizona · California · Florida · Kentucky · Louisiana · Missouri · Pennsylvania · Texas
NCT06014502 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer
Advanced Prostate Cancer, Metastatic Prostate Cancer
Genentech, Inc. · started 2026-04-29
Arizona · Tennessee
NCT07567846 on ClinicalTrials.gov ↗
Active Phase 3
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Non-alcoholic Steatohepatitis
Novo Nordisk A/S · started 2021-04-01
Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia
NCT04822181 on ClinicalTrials.gov ↗
Recruiting Phase 3
Pivotal Study of N-acetyl-L-leucine for CACNA1A
CACNA1A, Spinocerebellar Ataxia Type 6, Episodic Ataxia Type 2, Familial Hemiplegic Migraine-1
IntraBio Inc · started 2026-08-17
Maryland · Massachusetts · Texas
NCT07221292 on ClinicalTrials.gov ↗
Recruiting Phase 3
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
Cardiovascular Disease and Lipoprotein(a)
Novartis Pharmaceuticals · started 2026-05-11
Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia
NCT07517263 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Diabetes Mellitus, Type 1
Eli Lilly and Company · started 2026-02-05
Colorado · Florida · Pennsylvania · Texas · Virginia
NCT07222332 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm, Endometrial Neoplasms
Eli Lilly and Company · started 2025-08-06
California · Florida · Georgia · Massachusetts · Michigan · Missouri · New York · Pennsylvania
NCT07114601 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
UCB Biopharma SRL · started 2024-11-21
Arizona · Arkansas · California · Colorado · Florida · Georgia · Illinois · Indiana
NCT06617325 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LY3439539 in Participants With Alzheimer's Disease
Alzheimer Disease
Eli Lilly and Company · started 2026-05-21
California · Florida
NCT07598370 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
Non-small Cell Lung Cancer (NSCLC)
AstraZeneca · started 2025-10-31
Arizona · California · Colorado · Delaware · District of Columbia · Florida · Georgia · Illinois
NCT07291037 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia, Lymphoma, Small Lymphocytic
Eli Lilly and Company · started 2026-03-09
Alabama · Arizona · Florida · Minnesota · New York · Ohio · Texas
NCT07218341 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Diabetic Retinopathy
Boehringer Ingelheim · started 2024-05-15
Arizona · California · Colorado · Connecticut · Florida · Hawaii · Maine · Maryland
NCT06321302 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1
HIV-1-infection
Gilead Sciences · started 2026-06-15
Arizona · California · Colorado · Florida · Georgia · Michigan · Missouri · New Jersey
NCT07645287 on ClinicalTrials.gov ↗
Active Phase 3
Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity
Obesity and Overweight
Pfizer · started 2025-12-19
Arizona · California · Colorado · Florida · Georgia · Maryland · Missouri · Nebraska
NCT07311850 on ClinicalTrials.gov ↗
Active Phase 1
A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors
Renal Cell Carcinoma, Ovarian Tumor
Daiichi Sankyo · started 2020-12-22
Arizona · Colorado · Florida · Oklahoma · Tennessee
NCT04707248 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Neoplasms
Celgene · started 2018-07-19
Alabama · Arizona · California · Colorado · Connecticut · District of Columbia · Florida · Georgia
NCT03435796 on ClinicalTrials.gov ↗
Recruiting Phase 2
Personalized Neoantigen Vaccine Plus IL-12 (INO-9012) Versus Active Surveillance in Subjects With High-Risk HCC
HCC
Geneos Therapeutics · started 2026-09
Georgia · Louisiana · Maryland · Michigan · New York · Texas · Washington
NCT07722741 on ClinicalTrials.gov ↗
Recruiting Phase 1
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
Non-Small-Cell Lung, Esophageal Cancer, Cutaneous Melanoma
Pfizer · started 2026-04-08
Colorado · Connecticut · Tennessee · Virginia
NCT07519655 on ClinicalTrials.gov ↗
Recruiting
Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational Pathologic Analysis
Prostate Cancer Screening
Uro-1 Medical · started 2025-07-07
New York · North Carolina · South Carolina
NCT06830265 on ClinicalTrials.gov ↗
Recruiting Phase 3
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
Fibromyalgia
Axsome Therapeutics, Inc. · started 2026-01-14
Arizona · Arkansas · California · Connecticut · Florida · Georgia · Illinois · Kansas
NCT07398417 on ClinicalTrials.gov ↗
Recruiting Phase 3
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)
Eli Lilly and Company · started 2025-09-02
Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Idaho
NCT07157774 on ClinicalTrials.gov ↗
Active Phase 2
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA
ANCA Associated Vasculitis (AAV)
Novartis Pharmaceuticals · started 2025-03-13
Colorado · Florida · Illinois · Massachusetts · Michigan · Minnesota · North Carolina · Oregon
NCT06868290 on ClinicalTrials.gov ↗
Active Phase 1
A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3
Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3
Boehringer Ingelheim · started 2020-07-29
Georgia · Maryland · Missouri · Pennsylvania
NCT04429087 on ClinicalTrials.gov ↗
Active Phase 2
Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss
Obesity & Overweight, Mobility Disability, HOMA-IR
Veru Inc. · started 2026-03-26
Arizona · Florida · Louisiana · Maryland · Mississippi · New York · North Carolina · Texas
NCT07446998 on ClinicalTrials.gov ↗
Active
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular · started 2021-10-20
Alabama · Arizona · Arkansas · California · Colorado · Connecticut · District of Columbia · Florida
NCT05198674 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
Solid Tumor Cancer, Locally Advanced, Metastatic Solid Tumors, Lung Cancers
Avenzo Therapeutics, Inc. · started 2025-06-04
Arizona · California · Colorado · Connecticut · District of Columbia · Florida · Georgia · Massachusetts
NCT07038343 on ClinicalTrials.gov ↗
Recruiting Phase 4
Dabrafenib and/or Trametinib Rollover Study
Melanoma, Non Small Cell Lung Cancer, Solid Tumor, Rare Cancers
Novartis Pharmaceuticals · started 2018-01-26
Arizona · Maryland · Ohio · Texas
NCT03340506 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
Small-cell Lung Cancer
Zai Lab (Shanghai) Co., Ltd. · started 2025-11-30
California · Colorado · Connecticut · Florida · Illinois · Iowa · Kentucky · Maryland
NCT07218146 on ClinicalTrials.gov ↗
Recruiting
Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix
Prostate Cancer Detection
Sequenom, Inc. · started 2026-04-03
California · Idaho · Kentucky · Maryland · New York · South Carolina
NCT07543757 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Breast Neoplasms
Eli Lilly and Company · started 2026-05-13
Alabama · Arizona · California · Colorado · Florida · Georgia · Indiana · Kentucky
NCT07287098 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
First-in-Human Study of ICT01 in Patients With Advanced Cancer
Solid Tumor, Adult, Hematopoietic/Lymphoid Cancer
ImCheck Therapeutics, an Ipsen company · started 2020-03-05
Arizona · California · Connecticut · Florida · New York · Texas · Washington
NCT04243499 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Esophageal Cancer
Immunome, Inc. · started 2026-05-21
Florida · Massachusetts · Texas
NCT07578571 on ClinicalTrials.gov ↗
Recruiting Phase 1
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Solid Tumors, Sarcoma
Daiichi Sankyo · started 2024-11-14
Massachusetts · New York · Tennessee
NCT06644755 on ClinicalTrials.gov ↗
By invitation
Registry of Patients With Hypophosphatasia
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. · started 2015-01-20
Colorado · Connecticut · Florida · Georgia · Maryland · Massachusetts · Minnesota · Missouri
NCT02306720 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Hoffmann-La Roche · started 2022-08-30
Alabama · California · Colorado · District of Columbia · Florida · Maryland · Massachusetts · Michigan
NCT05271409 on ClinicalTrials.gov ↗
Active Phase 2/Phase 3
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus
Biogen · started 2022-09-13
Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana
NCT05531565 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
Early Breast Cancer
Novartis Pharmaceuticals · started 2024-02-28
Alabama · Alaska · Arizona · Arkansas · California · Colorado · District of Columbia · Florida
NCT05827081 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Carcinoma
Pfizer · started 2025-09-29
Alabama · Alaska · Arkansas · California · Colorado · Delaware · Florida · Georgia
NCT07144280 on ClinicalTrials.gov ↗
Recruiting Phase 1
An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease
Alzheimer s Disease
Voyager Therapeutics · started 2026-09-03
Florida
NCT07764146 on ClinicalTrials.gov ↗
Recruiting Phase 3
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
Intermediate Risk Non-Muscle Invasive Bladder Cancer
Ferring Pharmaceuticals · started 2024-10-01
Alabama · Arizona · Arkansas · California · Colorado · District of Columbia · Florida · Georgia
NCT06510374 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
Psoriasis, Overweight or Obesity
Eli Lilly and Company · started 2025-03-19
Arizona · California · Florida · Georgia · Indiana · Kentucky · Maryland · Massachusetts
NCT06857942 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation
Microvascular Inflammation
Biogen · started 2026-01-05
California · Kansas · Michigan · Minnesota · Missouri · Nebraska · New Jersey · North Carolina
NCT07219043 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)
Duchenne Muscular Dystrophy
Hoffmann-La Roche · started 2025-04-04
Arkansas · California · Georgia · Michigan · Texas · Virginia
NCT06450639 on ClinicalTrials.gov ↗
Recruiting
Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy
Bladder Cancer, Non-muscle Invasive Bladder Cancer
Photocure · started 2026-03-25
Florida · Michigan · New Jersey
NCT07144319 on ClinicalTrials.gov ↗
Active
A Study to Understand the Utility of the Force Feedback Instruments in Robotic Procedures Using da Vinci 5 Robot
Hernia, Inguinal, Hernia, Ventral, Colorectal, Thoracic
Intuitive Surgical · started 2025-05-24
California · Florida · Georgia · Illinois · Ohio · Texas
NCT06879912 on ClinicalTrials.gov ↗
Active Phase 1
DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer
Small Cell Lung Carcinoma (SCLC)
Boehringer Ingelheim · started 2024-02-14
Florida · Georgia
NCT06077500 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.
Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL), Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL)
Arvinas Inc. · started 2024-09-05
Connecticut · Florida · Michigan · New Jersey · New York · Ohio · Tennessee · Texas
NCT06393738 on ClinicalTrials.gov ↗
Recruiting
Efficacy and Safety of Acute Topical and Aromatic Essential Oil-Based Products for Cognitive Support
Healthy
dōTERRA International · started 2026-06-10
Utah
NCT07623811 on ClinicalTrials.gov ↗
By invitation Phase 3
An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE)
Biogen · started 2022-06-10
Arizona · California · Colorado · District of Columbia · Florida · Georgia · Massachusetts · Michigan
NCT05352919 on ClinicalTrials.gov ↗
Recruiting Phase 1
TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas
Lymphoma, Lymphoma, Non Hodgkin
Treeline Biosciences, Inc. · started 2025-06-23
California · Michigan · Missouri · New York · Pennsylvania · Tennessee · Texas
NCT07082803 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
Parkinsons Disease
Hoffmann-La Roche · started 2021-05-05
Alabama · Arizona · California · Colorado · Connecticut · Florida · Illinois · Kansas
NCT04777331 on ClinicalTrials.gov ↗
Recruiting Phase 2
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)
PIK3CA-related Overgrowth Spectrum (PROS)
Novartis Pharmaceuticals · started 2025-10-09
Missouri · North Carolina · Ohio · Oregon · Pennsylvania · Texas · Washington
NCT06997588 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
Generalized Anxiety Disorder
Definium Therapeutics US, Inc. · started 2025-01-29
Arkansas · California · Florida · Georgia · Maryland · Massachusetts · New Jersey · Ohio
NCT06809595 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis
Myasthenia Gravis, Generalized
Vertex Pharmaceuticals Incorporated · started 2026-05-13
California · Florida · Hawaii · Illinois · Nevada · South Carolina · Tennessee · Texas
NCT07501702 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Overweight, Obesity
Novo Nordisk A/S · started 2026-08-04
Georgia · Hawaii · Illinois · Indiana · Kentucky · North Carolina · South Carolina · Virginia
NCT07745504 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)
Acute Myeloid Leukemia
AbbVie · started 2026-06-30
California · Florida · Georgia · New York · Texas
NCT07581002 on ClinicalTrials.gov ↗
Starting soon Phase 1
A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity
Diabetes Mellitus, Type 1, Overweight, Obesity
Eli Lilly and Company · started 2026-09
Florida
NCT07803744 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer
AbbVie · started 2024-04-10
California · Florida · Georgia · Illinois · Kansas · Kentucky · Michigan · Missouri
NCT06236438 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Neovascular Age-related Macular Degeneration
AbbVie · started 2025-11-05
Arizona · California · Colorado · Florida · Georgia · Illinois · Indiana · Iowa
NCT07007065 on ClinicalTrials.gov ↗
Active Phase 3
Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide
Overweight, Obesity, Type 2 Diabetes
Novo Nordisk A/S · started 2025-11-05
Alabama · Arizona · California · Florida · Hawaii · Indiana · Nevada · New York
NCT07220759 on ClinicalTrials.gov ↗
Recruiting Phase 3
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Ulcerative Colitis, Obesity or Overweight
Eli Lilly and Company · started 2025-06-26
Alabama · California · Florida · Idaho · Illinois · Indiana · Kentucky · Louisiana
NCT06937086 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder
Bipolar-I Disorder With Mania or Mania With Mixed Features
Bristol-Myers Squibb · started 2025-06-11
Arkansas · California · Connecticut · Florida · Georgia · Illinois · New York · Ohio
NCT06951698 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
Schizophrenia
Bristol-Myers Squibb · started 2026-01-29
California · Florida · Georgia · Illinois · Massachusetts · New York · Ohio · Tennessee
NCT07288567 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms, PTSD, Post Traumatic Stress Disorder
COMPASS Pathways · started 2026-09
Florida · New York
NCT07570654 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Alnylam Pharmaceuticals · started 2026-08-17
Florida
NCT07636811 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain
Chronic Pain, Low Back Pain
Eli Lilly and Company · started 2026-08-12
Alabama · Arizona · California · Connecticut · Florida · Georgia · Illinois · Louisiana
NCT07641504 on ClinicalTrials.gov ↗
Recruiting Phase 1
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
Overweight, Obesity
Novo Nordisk A/S · started 2026-08-12
Kansas · Texas
NCT07767175 on ClinicalTrials.gov ↗
By invitation Phase 3
Open-Label Safety Study of AXS-14 in Subjects With Fibromyalgia
Fibromyalgia
Axsome Therapeutics, Inc. · started 2026-04-29
Arkansas · California · Florida · Georgia · Illinois · Kansas · Kentucky · Louisiana
NCT07637162 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
Locally Advanced Solid Tumors, Metastatic Solid Tumors, Lymphoma, Primary CNS Tumors
Turning Point Therapeutics, Inc. · started 2020-03-12
California · Colorado · Florida · Georgia · Maine · Massachusetts · Missouri · New Jersey
NCT04094610 on ClinicalTrials.gov ↗
Active
Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases
Inquis Medical, Inc. · started 2023-09-20
Arizona · California · Connecticut · District of Columbia · Georgia · Illinois · Indiana · Louisiana
NCT05907564 on ClinicalTrials.gov ↗
Recruiting
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
Parkinson's Disease
Bayer · started 2026-07-21
Arizona · California · Connecticut · Florida · Georgia · Illinois · Maryland · Massachusetts
NCT07330258 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)
Primary Immune Thrombocytopenia (ITP), Primary Evans Syndrome (ES)
Novartis Pharmaceuticals · started 2026-08-04
Arkansas · Connecticut · Florida · Illinois · Louisiana · Minnesota · Montana · New Jersey
NCT07421167 on ClinicalTrials.gov ↗
Active Phase 1
DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers
Neuroendocrine Neoplasms
Boehringer Ingelheim · started 2024-01-22
Florida · Georgia · Illinois · New Jersey · Pennsylvania
NCT06132113 on ClinicalTrials.gov ↗
Starting soon Phase 2
A Study to Evaluate BMS-986511 in Adults With Major Depressive Disorder
Major Depressive Disorder
Bristol-Myers Squibb · started 2026-10-30
Arizona · Arkansas · California · Florida · Georgia · Maryland · Massachusetts · New York
NCT07772531 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems
Healthy, Hepatic Impairment
Boehringer Ingelheim · started 2025-07-17
California · Florida · Texas
NCT07023354 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Episodic Migraine in Adults
Episodic Migraine
Ipsen · started 2023-09-29
Alabama · Arizona · California · Connecticut · Florida · Illinois · Indiana · Maryland
NCT06047457 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
Osteoarthritis, Knee, Chronic Pain
Eli Lilly and Company · started 2026-06-25
Alabama · Arizona · California · Connecticut · Florida · Georgia · Illinois · Louisiana
NCT07641517 on ClinicalTrials.gov ↗
Active
A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)
Lumbar Spinal Stenosis
Boston Scientific Corporation · started 2020-01-30
California · Florida · Georgia · Idaho · Illinois · Kansas · Massachusetts · Michigan
NCT04192591 on ClinicalTrials.gov ↗
Active Phase 3
177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer
Metastasis From Malignant Tumor of Prostate
Curium US LLC · started 2022-02-14
Arizona · California · Florida · Illinois · Maryland · Michigan · Minnesota · Missouri
NCT05204927 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Obesity, Overweight and/or Obesity, Overweight
Pfizer · started 2026-06-10
California · Florida · Illinois · Indiana · Kentucky · Maryland · Michigan · Nebraska
NCT07595549 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
Non Small Cell Lung Carcinoma
AbbVie · started 2025-03-06
Arizona · California · Colorado · Florida · Illinois · Indiana · Kansas · Massachusetts
NCT06772623 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema
Eczema
Pfizer · started 2025-07-24
Alabama · Arkansas · California · Florida · Idaho · Indiana · Missouri · South Carolina
NCT06807268 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
Moderate to Severe Glabellar Lines
Ipsen · started 2026-02-27
Alabama · Arizona · California · Florida · Maryland · South Carolina · Texas · Virginia
NCT07427797 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
Bowel Preparation
Ferring Pharmaceuticals · started 2022-06-23
Alabama · California · Maryland
NCT04113382 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2a/b Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Sjögren's Disease
Sjögren's Disease
Novartis Pharmaceuticals · started 2026-08-24
Florida · Oklahoma · Texas
NCT07737743 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of d-MAPPS™ Ophthalmic Solution in Adults With Chronic Ocular Graft-Versus-Host Disease (oGVHD)
oGVHD, Ocular Graft Versus Host Disease
Regenerative Ocular Immunobiologics LLC · started 2026-09
California · Florida · Massachusetts
NCT07776210 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO
Neovascular Age-Related Macular Degeneration (NVAMD), Branch Retinal Vein Occlusion (BRVO)
EyeBiotech Ltd. · started 2025-09-12
Arizona · California · Colorado · Florida · Illinois · Maryland · Mississippi · New Jersey
NCT07205887 on ClinicalTrials.gov ↗
Recruiting Phase 3
Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa
Epidermolysis Bullosa (EB)
Paradigm Therapeutics · started 2026-07-21
California · South Carolina
NCT07482787 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Multiple Sclerosis (MS) Primary Progressive
Zenas BioPharma (USA), LLC · started 2026-03-23
Arizona · California · Florida · Kansas · Missouri · New Jersey · North Carolina · Ohio
NCT07067463 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Ovarian Neoplasms, Breast Neoplasms, Pancreatic Intraductal Neoplasms, Colorectal Neoplasms
Eli Lilly and Company · started 2025-10-22
California · Florida · Indiana · Maryland · Massachusetts · Michigan · Minnesota · Missouri
NCT07213791 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
Bipolar Disorder
Eli Lilly and Company · started 2025-11-24
California · Connecticut · Florida · Georgia · Iowa · Maryland · Massachusetts · Pennsylvania
NCT07286175 on ClinicalTrials.gov ↗
Recruiting Phase 1
Study of the Effect of Haemodialysis on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone/Dapagliflozin
Kidney Failure
AstraZeneca · started 2026-08-06
Florida
NCT07754331 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm
Eli Lilly and Company · started 2024-07-01
California · Colorado · Florida · Illinois · Indiana · Massachusetts · Michigan · Missouri
NCT06465069 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Ulcerative Colitis
AbbVie · started 2025-07-28
Arizona · California · Florida · Georgia · Illinois · New Jersey · Ohio · Pennsylvania
NCT07071519 on ClinicalTrials.gov ↗
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Priya Life Science (2026). Clinical Trials in the USA Tracker. Available at: https://priyalifescience.com/clinical-trials-usa (Accessed: 6 September 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one US site, most recently updated first, refreshed daily. This is a curated slice of the full registry, not every US trial. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish and EU sites, see our Ireland and EU trackers.