Naltrexone is named as an intervention in 4 current clinical trials in our USA register. 2 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is AgelessRx (2). The most-studied condition is Aging.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
NCT07092618 · ClinicalTrials.gov ↗ · Longevity, GLP-1, Geroscience
|
Phase 2/3 | Recruiting | AgelessRx | USA |
|
iSTEP-N 101b: Pharmacokinetics and Safety Study of Low- and High-Dose Naltrexone Implants vs Monthly Vivitrol in Healthy Volunteers
NCT07064564 · ClinicalTrials.gov ↗ · Opioid Use Disorder
|
Phase 1 | Recruiting | Akyso Therapeutics, LLC | USA |
|
Electromagnetic Immunotherapy Mapping and Cytokine Forecasting Study (QSIT)
NCT07221565 · ClinicalTrials.gov ↗ · Systemic Lupus Erythematosus, Rheumatoid Arthritis, Multiple Sclerosis
|
Phase 1/2 | By invitation | Truway Health, Inc. | USA |
|
Combination Gerotherapeutic Interventions for Healthspan Improvement
NCT07475546 · Healthspan Improvement, Aging, Longevity
|
Phase 3 | Active, closed | AgelessRx | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Lead sponsor | Trials |
|---|---|
| AgelessRx | 2 |
| Truway Health, Inc. | 1 |
| Akyso Therapeutics, LLC | 1 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 4 | 2 |
A trial with sites in more than one country appears in each of those registers.
4 current trials in our USA register name Naltrexone as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.
Yes. 2 of the 4 trials are recruiting: 2 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
AgelessRx (2), Truway Health, Inc (1) and Akyso Therapeutics, LLC (1). The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Naltrexone works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Naltrexone works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Naltrexone (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.