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Plain-English drug profiles · openFDA data

Drug Directory

Clear, plain-English profiles of 53 major prescription medicines — what each is used for, its class and manufacturer, when it was approved, and whether it's currently in shortage. Live from official FDA data.

Aduhelm
Aducanumab
An early anti-amyloid Alzheimer's therapy.
Anti-amyloid antibody
Advair
Fluticasone/salmeterol
A combination inhaler for asthma and COPD.
ICS/LABA inhaler
Amoxil
Amoxicillin
A first-line antibiotic for many common bacterial infections.
Penicillin antibiotic
Avastin
Bevacizumab
An anti-angiogenesis antibody used in colorectal, lung and other cancers.
VEGF inhibitor
Comirnaty
Tozinameran
The Pfizer-BioNTech mRNA COVID-19 vaccine.
mRNA vaccine
Cosentyx
Secukinumab
A biologic for psoriasis, psoriatic arthritis and ankylosing spondylitis.
IL-17A inhibitor
Crestor
Rosuvastatin
A potent statin for lowering LDL cholesterol.
Statin
Darzalex
Daratumumab
An antibody therapy for multiple myeloma.
CD38 monoclonal antibody
Dupixent
Dupilumab
A biologic for eczema, asthma and other type-2 inflammatory conditions.
IL-4/13 inhibitor
Eliquis
Apixaban
An oral anticoagulant to prevent stroke and treat clots.
Factor Xa inhibitor
Enbrel
Etanercept
An anti-TNF biologic for rheumatoid arthritis and psoriasis.
TNF inhibitor
Entresto
Sacubitril/valsartan
A combination therapy for chronic heart failure.
ARNI
Epclusa
Sofosbuvir/velpatasvir
A pan-genotypic cure for chronic hepatitis C.
Direct-acting antiviral
Farxiga
Dapagliflozin
An oral therapy for diabetes, heart failure and chronic kidney disease.
SGLT2 inhibitor
Fasenra
Benralizumab
A biologic for severe eosinophilic asthma.
IL-5 receptor antibody
Gleevec
Imatinib
A landmark targeted therapy for chronic myeloid leukaemia and GIST.
Tyrosine kinase inhibitor
Glucophage
Metformin
The first-line oral medicine for type-2 diabetes.
Biguanide
Herceptin
Trastuzumab
A targeted antibody for HER2-positive breast and stomach cancers.
HER2 monoclonal antibody
Humira
Adalimumab
A widely used anti-TNF biologic for rheumatoid arthritis, psoriasis and Crohn's.
TNF inhibitor
Ibrance
Palbociclib
An oral therapy for hormone-receptor-positive advanced breast cancer.
CDK4/6 inhibitor
Imbruvica
Ibrutinib
An oral targeted therapy for chronic lymphocytic leukaemia and lymphomas.
BTK inhibitor
Jardiance
Empagliflozin
An oral therapy for type-2 diabetes, heart failure and kidney disease.
SGLT2 inhibitor
Keytruda
Pembrolizumab
An immunotherapy antibody used across many cancers, from melanoma to lung cancer.
PD-1 checkpoint inhibitor
Lantus
Insulin Glargine
A long-acting basal insulin for type-1 and type-2 diabetes.
Long-acting insulin
Leqembi
Lecanemab
An antibody that clears amyloid plaques in early Alzheimer's disease.
Anti-amyloid antibody
Lipitor
Atorvastatin
A cholesterol-lowering statin, among the most prescribed medicines ever.
Statin
Lynparza
Olaparib
A targeted oral therapy for BRCA-mutated ovarian, breast and prostate cancers.
PARP inhibitor
Lyrica
Pregabalin
An oral medicine for nerve pain, epilepsy and anxiety.
Anticonvulsant
Mounjaro
Tirzepatide
A dual-incretin therapy for type-2 diabetes and weight management.
GIP/GLP-1 receptor agonist
Norvasc
Amlodipine
A common oral medicine for high blood pressure.
Calcium channel blocker
Ocrevus
Ocrelizumab
A B-cell antibody for relapsing and primary-progressive multiple sclerosis.
CD20 monoclonal antibody
Opdivo
Nivolumab
A checkpoint-inhibitor immunotherapy for melanoma, lung, kidney and other cancers.
PD-1 checkpoint inhibitor
Ozempic
Semaglutide
A GLP-1 therapy for type-2 diabetes and, as Wegovy, chronic weight management.
GLP-1 receptor agonist
Paxlovid
Nirmatrelvir/ritonavir
An oral antiviral for COVID-19 in people at risk of severe disease.
Antiviral
Plavix
Clopidogrel
An antiplatelet medicine to prevent heart attack and stroke.
Antiplatelet
Prilosec
Omeprazole
An acid-reducing medicine for reflux and ulcers.
Proton-pump inhibitor
Remicade
Infliximab
An anti-TNF infusion biologic for inflammatory bowel disease and arthritis.
TNF inhibitor
Revlimid
Lenalidomide
An oral immunomodulator for multiple myeloma and related blood cancers.
Immunomodulatory agent
Rituxan
Rituximab
A B-cell antibody for lymphomas, leukaemia and autoimmune disease.
CD20 monoclonal antibody
Spinraza
Nusinersen
An intrathecal therapy for spinal muscular atrophy.
Antisense oligonucleotide
Spiriva
Tiotropium
A once-daily inhaler for COPD.
Long-acting anticholinergic
Stelara
Ustekinumab
A biologic for psoriasis, psoriatic arthritis and Crohn's disease.
IL-12/23 inhibitor
Synthroid
Levothyroxine
A daily replacement hormone for an underactive thyroid.
Thyroid hormone
Tagrisso
Osimertinib
A targeted oral therapy for EGFR-mutated non-small-cell lung cancer.
EGFR inhibitor
Tecentriq
Atezolizumab
A PD-L1 immunotherapy used in lung, bladder and other cancers.
PD-L1 checkpoint inhibitor
Trulicity
Dulaglutide
A once-weekly GLP-1 injection for type-2 diabetes.
GLP-1 receptor agonist
Ventolin
Salbutamol
The classic blue reliever inhaler for asthma.
Short-acting bronchodilator
Xarelto
Rivaroxaban
An oral anticoagulant for clot prevention and treatment.
Factor Xa inhibitor
Xeljanz
Tofacitinib
An oral JAK inhibitor for rheumatoid arthritis and ulcerative colitis.
JAK inhibitor
Xtandi
Enzalutamide
An oral therapy for advanced prostate cancer.
Androgen receptor inhibitor
Zithromax
Azithromycin
A short-course antibiotic for respiratory and other infections.
Macrolide antibiotic
Zolgensma
Onasemnogene Abeparvovec
A one-time gene therapy for spinal muscular atrophy in infants.
Gene therapy
Zoloft
Sertraline
A widely used SSRI for depression and anxiety.
SSRI antidepressant
No medicines match your search.

Profiles combine a curated plain-English summary with live label, approval, manufacturer and shortage data from the U.S. FDA via the openFDA API. For general information only — not medical advice. Related: Drug Shortages Tracker, FDA Approvals, Irish Medicines Database.