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Hepatitis C Antivirals

Also called direct-acting antivirals, DAAs, hepatitis C cure

Direct-acting antivirals turned hepatitis C from a lifelong liver disease into a curable infection. They block the specific viral proteins the virus needs to copy itself, and a course of 8 to 12 weeks of tablets clears the virus in over 95% of people — with few side effects, and no interferon injections. It is one of the great therapeutic successes of the last two decades.

Reviewed by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from official FDA data · Last verified · Editorial standards
What this class is used for
Chronic hepatitis C infection (all major genotypes)

4 Hepatitis C Antivirals in this directory

Epclusa
Sofosbuvir/velpatasvir
A pan-genotypic cure for chronic hepatitis C.
Mavyret
Glecaprevir/pibrentasvir
An oral daily combination medication used to cure chronic hepatitis C infection.
Harvoni
Ledipasvir/sofosbuvir
An oral once-daily single-tablet regimen used to treat chronic hepatitis C.
Sovaldi
Sofosbuvir
An oral direct-acting antiviral tablet used in combination to treat chronic hepatitis C.

Compare Hepatitis C Antivirals side by side

Epclusa VS Mavyret Epclusa VS Harvoni Mavyret VS Harvoni

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How this page is built

The facts on this page are pulled directly from official U.S. FDA datasets — they are not written from memory. Each field below names the dataset it came from, so you can check it yourself.

Plain-English summaries and drug-class explainers are written and reviewed by Sreepriya Prasannan (MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany). Data is retrieved automatically from the sources above and cross-checked with AI-assisted verification (Anthropic's Claude) — brand and generic names are matched against the exact FDA product record so that a combination product or a different formulation cannot be mistaken for the drug on this page. An editor reviews the result before publication. We describe this in full in our editorial standards and corrections policy. The FDA data on this page was last retrieved on 12 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.