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Hepatitis C Antivirals

Also called direct-acting antivirals, DAAs, hepatitis C cure

Direct-acting antivirals turned hepatitis C from a lifelong liver disease into a curable infection. They block the specific viral proteins the virus needs to copy itself, and a course of 8 to 12 weeks of tablets clears the virus in over 95% of people — with few side effects, and no interferon injections. It is one of the great therapeutic successes of the last two decades.

What this class is used for
Chronic hepatitis C infection (all major genotypes)

4 Hepatitis C Antivirals in this directory

Epclusa
Sofosbuvir/velpatasvir
A pan-genotypic cure for chronic hepatitis C.
Mavyret
Glecaprevir/pibrentasvir
An oral daily combination medication used to cure chronic hepatitis C infection.
Harvoni
Ledipasvir/sofosbuvir
An oral once-daily single-tablet regimen used to treat chronic hepatitis C.
Sovaldi
Sofosbuvir
An oral direct-acting antiviral tablet used in combination to treat chronic hepatitis C.

Compare Hepatitis C Antivirals side by side

Epclusa VS Mavyret Epclusa VS Harvoni Mavyret VS Harvoni

Browse other drug classes

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Class descriptions are written by the Priya Life Science editorial team. Individual drug pages combine that summary with live label, approval, manufacturer and shortage data from the U.S. FDA via the openFDA API. This page is general information and is not medical advice — it is not exhaustive, drugs within a class are not automatically interchangeable, and approvals and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions. Always consult the official prescribing information and your clinician or pharmacist. Related: Drug Shortages Tracker · FDA Approvals · All drug comparisons