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CD20 Monoclonal Antibodies

Also called anti-CD20 therapy, B-cell depleting antibodies

CD20 is a protein found on the surface of B-cells. Antibodies that bind it flag those B-cells for destruction, wiping out the population and rebooting it. That single mechanism turns out to be useful in two very different settings: B-cell cancers such as lymphoma, and autoimmune diseases where B-cells drive the damage, including multiple sclerosis.

What this class is used for
Non-Hodgkin lymphoma, chronic lymphocytic leukaemia, rheumatoid arthritis, multiple sclerosis

2 CD20 Antibodies in this directory

Rituxan
Rituximab
A B-cell antibody for lymphomas, leukaemia and autoimmune disease.
Ocrevus
Ocrelizumab
A B-cell antibody for relapsing and primary-progressive multiple sclerosis.

Browse other drug classes

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Class descriptions are written by the Priya Life Science editorial team. Individual drug pages combine that summary with live label, approval, manufacturer and shortage data from the U.S. FDA via the openFDA API. This page is general information and is not medical advice — it is not exhaustive, drugs within a class are not automatically interchangeable, and approvals and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions. Always consult the official prescribing information and your clinician or pharmacist. Related: Drug Shortages Tracker · FDA Approvals · All drug comparisons