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Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma ◆ Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide ◆ The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany ◆ Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact ◆ The Pharmacist's Role: How Community Pharmacies in Ireland and the UK Are Adapting as Patients Bypass High-Street Stores for Direct Delivery ◆ GLP-1 Therapeutics and Clinical Research Updates: Brain Reward Mapping, Oral Small Molecules, and Triple-Agonist Horizons ◆ Rinn Pharma & Biopharma Joins NordicPharmaTrain Network to Accelerate European Research & Advanced Manufacturing ◆ Markets Surge as August Opens: $400B Big Pharma Merger Speculation & AstraZeneca Deal Talks Grab Global Headlines ◆ Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma ◆ Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide ◆ The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany ◆ Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact ◆ The Pharmacist's Role: How Community Pharmacies in Ireland and the UK Are Adapting as Patients Bypass High-Street Stores for Direct Delivery ◆ GLP-1 Therapeutics and Clinical Research Updates: Brain Reward Mapping, Oral Small Molecules, and Triple-Agonist Horizons ◆ Rinn Pharma & Biopharma Joins NordicPharmaTrain Network to Accelerate European Research & Advanced Manufacturing ◆ Markets Surge as August Opens: $400B Big Pharma Merger Speculation & AstraZeneca Deal Talks Grab Global Headlines ◆
Updated 19 Aug 2026 · ClinicalTrials.gov

Clinical Trials in Ireland

Every active and recruiting clinical study with an Irish site — searchable by condition, sponsor, phase and location. Refreshed daily from the ClinicalTrials.gov registry.

52
Recruiting now
94
Active studies
Recruiting
Understanding the Feasibility of a Co-designed Pre-radiotherapy Exercise Programme - A Single-arm Study
Lung Cancer
Queen's University, Belfast · started 2026-06-10
NCT07554677 on ClinicalTrials.gov ↗
Recruiting Phase 3
The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity
Venous Thromboembolism, Postpartum Period, Aspirin, Low Molecular Weight Heparin
University of Calgary · started 2026-06-04
📍 Dublin
NCT06494878 on ClinicalTrials.gov ↗
Recruiting Phase 2
INSPIRE: INnovative SABR for Prostate Cancer All IREland
Prostate Adenocarcinoma
Cancer Trials Ireland · started 2026-04-23
📍 Dublin · Cork · Waterford
NCT07552168 on ClinicalTrials.gov ↗
Recruiting
Frailty in Older Adults With Prostate Cancer: a Prospective Cohort Study
Frailty at Older Adults, Prostate Cancer
University of Limerick · started 2026-04-23
📍 Limerick
NCT07605936 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression
Ovarian Cancer
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc · started 2026-04-17
📍 Cork · Dublin
NCT07546500 on ClinicalTrials.gov ↗
Recruiting Phase 3
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Boehringer Ingelheim · started 2026-04-13
📍 Cork
NCT07472517 on ClinicalTrials.gov ↗
Starting soon
Self-Expanding Hydra Transcatheter Heart Valve (THV) Series Versus Balloon-Expandable Devices for Valve-In-Valve Transcatheter Aortic Valve Implantation (TAVI) for Patients With Failed Surgical Aortic Bioprosthesis.
AORTIC VALVE DISEASES, Valve-in-valve Procedures, Surgical Valve Replacement, Valve Disease, Aortic
National University of Ireland, Galway, Ireland · started 2026-04
📍 Galway
NCT07524595 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Non-small Cell Lung Cancer (NSCLC)
Bristol-Myers Squibb · started 2026-03-16
📍 Cork · Dublin
NCT07361497 on ClinicalTrials.gov ↗
Starting soon
Strategic Timing of Resistance Training to Guard Against Antipsychotic-Induced Metabolic Syndrome
Psychosis
University College Dublin · started 2026-02-01
📍 Dublin
NCT07386483 on ClinicalTrials.gov ↗
Recruiting Phase 4
Arthrosamid vs. Steroid for the Management of Knee Osteoarthritis
Osteo Arthritis Knee, Osteoarthritis, Intraarticular Injection
Cappagh National Orthopaedic Hospital · started 2026-01-29
📍 Dublin
NCT07489521 on ClinicalTrials.gov ↗
Starting soon
Assessing Sensor-Guided Compression Therapy for Venous Leg Ulcers Healing Outcomes
Venous Leg Ulcer (VLU)
Feeltect Limited · started 2026-01-15
📍 Galway
NCT07268482 on ClinicalTrials.gov ↗
Recruiting
Pre-Operative Nurse-Led Education With Direct Physiotherapy Referral to Reduce Post-Prostatectomy Incontinence
Prostate Cancer, Urinary Incontinence, Postoperative Complications, Radical Prostatectomy
Royal College of Surgeons, Ireland · started 2025-12-20
📍 Beaumont
NCT07426861 on ClinicalTrials.gov ↗
Recruiting
OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour Patients
Primary Brain Tumour, Glioblastoma, Brain Neoplasms
Royal College of Surgeons, Ireland · started 2025-12-18
📍 Dublin
NCT07426848 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder, Depression Disorders
Cybin IRL Limited · started 2025-12-10
📍 Dublin · Galway
NCT06793397 on ClinicalTrials.gov ↗
Recruiting
Precision Oncology Clinical Diagnostic Study In Primary and Metastatic Breast Cancer (PRISM)
Breast Cancer
Cancer Trials Ireland · started 2025-11-11
📍 Dublin · Cork · Galway
NCT07425002 on ClinicalTrials.gov ↗
By invitation
Impact of Cooling Mats on Vasomotor Symptoms in Patients Receiving Endocrine Therapy
Hot Flashes, Sleep, Hormonal, Cancer
Sligo General Hospital · started 2025-11-10
📍 Sligo
NCT07422727 on ClinicalTrials.gov ↗
Recruiting
Effectiveness of Ultrasound-Guided Versus Traditional IV Insertion by Oncology Nurses in Adult Population Recieving Systemic Anti-cancer Therapy
Cancer
University of Galway · started 2025-10-20
📍 Galway
NCT07208175 on ClinicalTrials.gov ↗
Recruiting
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
St. James's Hospital, Ireland · started 2025-09-01
📍 Dublin
NCT07160868 on ClinicalTrials.gov ↗
Recruiting
The Satiety Control Optimization by Nutritional Enhancement Study
Metabolic Diseases, Type 2 Diabetes, Cardiovascular Disease
University College Cork · started 2025-08-18
📍 Cork
NCT07420023 on ClinicalTrials.gov ↗
Recruiting
A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer
Barrett's Esophagus, Esophageal Adenocarcinoma
University Hospital, Antwerp · started 2025-08-13
📍 Dublin
NCT06523374 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)
Neoplasms, Lung
GlaxoSmithKline · started 2025-08-11
📍 Dublin
NCT07099898 on ClinicalTrials.gov ↗
Recruiting Phase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals · started 2025-07-02
📍 Dublin
NCT07052903 on ClinicalTrials.gov ↗
Recruiting
SURVEY-CNS: A Feasibility Study of Randomising Women and Men With HER2-Positive Metastatic Breast Cancer to Central Nervous System Surveillance Versus No Surveillance
Breast Cancer, HER2-Positive Metastatic Breast Cancer
Royal College of Surgeons, Ireland · started 2025-06-01
📍 Beaumont
NCT07503717 on ClinicalTrials.gov ↗
Recruiting Phase 4
Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatment With Efanesoctocog Alfa
Hemophilia A
Swedish Orphan Biovitrum · started 2025-05-21
📍 Dublin
NCT06940830 on ClinicalTrials.gov ↗
Recruiting
PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis
Progressive Pulmonary Fibrosis, Interstitial Lung Disease
University of Massachusetts, Worcester · started 2025-05-01
📍 Dublin
NCT06855329 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Carcinoma, Non-Small-Cell Lung
Mirati Therapeutics Inc. · started 2025-04-24
📍 Cork · Dublin
NCT06875310 on ClinicalTrials.gov ↗
By invitation Phase 2
A Study to Learn About the Long-Term Health of Adult Participants From a Previous Study of a New Melanoma Treatment
Melanoma
Regeneron Pharmaceuticals · started 2025-04-14
📍 Dublin
NCT06848088 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.
Advanced Solid Tumors Cancer, MSI-H Cancer
Nimbus Wadjet, Inc. · started 2025-03-31
📍 Dublin
NCT06898450 on ClinicalTrials.gov ↗
Recruiting
Assessing Intellectual and Motor Outcomes in High-risk Infants
Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
University College Cork · started 2025-03-21
📍 Cork · Dublin
NCT06857539 on ClinicalTrials.gov ↗
Starting soon
An Educational Intervention to Improve the Success of Intubation in Newborns Using a Video Laryngoscope by Reducing the Time the Procedure Takes.
Respiratory Distress Syndrome, Newborn, Endotracheal Intubation, Neonatal Intubation Performance, Prematurity
University College Dublin · started 2025-03
📍 Dublin
NCT06898801 on ClinicalTrials.gov ↗
Recruiting
Inpatient Post-Acute Rehabilitation For Patients in the Midwest: a Prospective Cohort Study of Clinical Characteristics and Process Outcomes
Rehabilitation, Frailty, Complex Patients in Rehabilitation Phase
University of Limerick · started 2025-02-22
📍 Limerick
NCT07351526 on ClinicalTrials.gov ↗
Active Phase 3
Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease
Breast Cancer
Pfizer · started 2025-01-06
📍 Dublin
NCT06760637 on ClinicalTrials.gov ↗
Recruiting
Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
Amyotrophic Lateral Sclerosis, Motor Neurone Disease
University of Dublin, Trinity College · started 2024-11-21
📍 Dublin
NCT06820008 on ClinicalTrials.gov ↗
Active Phase 4
A Study on Safety and Effectiveness of Long-term Treatment With Vamorolone in Boys With Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy
Santhera Pharmaceuticals · started 2024-11-10
📍 Dublin
NCT06713135 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC · started 2024-10-21
📍 Cork · Dublin
NCT06623422 on ClinicalTrials.gov ↗
Active
Safety and Tolerance of a Novel Three-Strain Probiotic in Healthy Adults
Healthy Adults
Pendulum Therapeutics · started 2024-09-23
📍 Cork
NCT07566884 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma
Monoclonal Gammopathy of Undetermined Significance (MGUS), Smoldering Multiple Myeloma (SMM)
Regeneron Pharmaceuticals · started 2024-09-16
📍 Galway · Cork · Dublin
NCT06140524 on ClinicalTrials.gov ↗
Recruiting Phase 3
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
Pulmonary Arterial Hypertension
Gossamer Bio USA, Inc. · started 2024-09-03
📍 Dublin
NCT06274801 on ClinicalTrials.gov ↗
Recruiting Phase 4
Fibrosis Lessens After Metabolic Surgery
Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis
The Cleveland Clinic · started 2024-07-11
📍 Dublin
NCT06374875 on ClinicalTrials.gov ↗
Active Phase 2
SalT Supplementation in Older Adults With Orthostatic Intolerance Disorders
Orthostatic Hypotension
University of Galway · started 2024-07-09
📍 Galway
NCT06188663 on ClinicalTrials.gov ↗
Recruiting
The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Molars
Dental Caries, Fissure Sealant
University of Dublin, Trinity College · started 2024-06-05
📍 Dublin
NCT06608563 on ClinicalTrials.gov ↗
Starting soon
Evaluating a Targeted Selective Speech, Language, and Communication Intervention at Scale - Protocol for the 'Happy Talk' Cluster Randomised Controlled Trial.
Developmental Language Disorder and Language Impairment, Deprivation
University College Cork · started 2024-06
📍 Dublin · Galway · Wexford · Wicklow
NCT06460090 on ClinicalTrials.gov ↗
Recruiting
Remote Assessment of Signs and Symptoms in Palliative Care
Palliative Care, Vital Signs, Remote Monitoring
Our Lady's Hospice and Care Services · started 2024-04-01
📍 Dublin
NCT06587321 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
Low Grade Serous Ovarian Cancer
Verastem, Inc. · started 2024-03-18
📍 Dublin
NCT06072781 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
Hemolytic Disease of the Fetus and Newborn
Janssen Research & Development, LLC · started 2023-12-20
📍 Dublin
NCT05912517 on ClinicalTrials.gov ↗
Recruiting Phase 3
Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)
ER-positive Breast Cancer, HER2-negative Breast Cancer, Stage IIB Breast Cancer, Stage III Breast Cancer
European Organisation for Research and Treatment of Cancer - EORTC · started 2023-12-15
📍 Dublin · Waterford
NCT05512364 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC · started 2023-12-06
📍 Dublin
NCT06077760 on ClinicalTrials.gov ↗
By invitation Phase 3
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy
Myositis, Active Idiopathic Inflammatory Myopathy, Dermatomyositis, Polymyositis
argenx · started 2023-09-12
📍 Dublin
NCT05979441 on ClinicalTrials.gov ↗
Active
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
Cardiac Arrest With Successful Resuscitation, Hypoxia, Brain
Region Skane · started 2023-08-17
📍 Dublin
NCT05564754 on ClinicalTrials.gov ↗
Active
PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds
Wound Surgical, Wound Infection, Cosmesis
Royal College of Surgeons, Ireland · started 2023-07-14
📍 Castlebar · Dublin · Galway · Letterkenny · Limerick · Sligo
NCT05977816 on ClinicalTrials.gov ↗
Recruiting
Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study
Friedreich Ataxia
Friedreich's Ataxia Research Alliance · started 2023-06-28
📍 Dublin
NCT06016946 on ClinicalTrials.gov ↗
By invitation Phase 2/Phase 3
A Clinical Trial to Investigate Long-term Safety, Tolerability, and Efficacy of Weekly Subcutaneous Doses With TransCon CNP in Children and Adolescents With Achondroplasia
Achondroplasia
Ascendis Pharma Growth Disorders A/S · started 2023-06-21
📍 Dublin
NCT05929807 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Breast Cancer, Solid Tumors, Adult
Eli Lilly and Company · started 2023-04-17
📍 Dublin
NCT05768139 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
Haemophilia A, Haemophilia A With Inhibitors
Novo Nordisk A/S · started 2023-02-13
📍 Dublin
NCT05685238 on ClinicalTrials.gov ↗
Recruiting
Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis
Late-Onset Neonatal Sepsis, Extreme Prematurity, Neonatal Hypotension
Mount Sinai Hospital, Canada · started 2023-02-06
📍 Cork · Dublin
NCT05347238 on ClinicalTrials.gov ↗
Active Phase 3
A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated · started 2022-11-08
📍 Cork · Dublin · Limerick
NCT05444257 on ClinicalTrials.gov ↗
Active
The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study
Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates · started 2022-10-25
📍 Galway
NCT05409976 on ClinicalTrials.gov ↗
Active
APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
Appetite Loss, Physical Inactivity, Undernutrition, Anorexia of Aging
University College Dublin · started 2022-09-22
📍 Dublin
NCT05608707 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT
Prostate Cancer
Institute of Cancer Research, United Kingdom · started 2022-09-09
📍 Cork · Dublin · Limerick
NCT05613023 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping
Duchenne Muscular Dystrophy (DMD)
Dyne Therapeutics · started 2022-08-12
📍 Dublin
NCT05524883 on ClinicalTrials.gov ↗
Recruiting
Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome
ARDS, Human, Lung Ultrasound, Mechanical Ventilation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · started 2022-08-09
📍 Galway
NCT05492344 on ClinicalTrials.gov ↗
Active Phase 3
Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Multiple Myeloma
Celgene · started 2022-06-23
📍 Cork · Dublin · Galway
NCT04975997 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated · started 2022-03-30
NCT05312879 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.
CDKL5 Deficiency Disorder, Generalized Tonic Clonic Seizure, Epileptic Spasm, Refractory Seizures
Zogenix, Inc. · started 2022-03-08
📍 Dublin
NCT05064878 on ClinicalTrials.gov ↗
Active
Direct Measurement of Microstructure of Ingestive Behaviour After Initiation of GLP-1 Receptor Agonist Treatment at Maximum Dose (DIGRAT)
Metabolic Disease, Obesity & Overweight
University College Dublin · started 2022-02-17
📍 Dublin
NCT07457424 on ClinicalTrials.gov ↗
Recruiting
Precision Diagnosis and Care for Families With Pulmonary Fibrosis in Ireland
Connective Tissue Diseases, Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Familial Idiopathic Pulmonary Fibrosis
Royal College of Surgeons, Ireland · started 2021-09-28
📍 Dublin
NCT06702228 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Beta-only IL-2 ImmunoTherapY Study
Advanced Solid Tumor, Unresectable Solid Tumor, Clear Cell Renal Cell Carcinoma, Triple Negative Breast Cancer
Medicenna Therapeutics, Inc. · started 2021-08-27
📍 Dublin
NCT05086692 on ClinicalTrials.gov ↗
Active Phase 3
A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
Breast Cancer
AstraZeneca · started 2021-06-22
📍 Cork · Dublin
NCT04739761 on ClinicalTrials.gov ↗
Active Phase 3
Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)
Breast Neoplasms
Merck Sharp & Dohme LLC · started 2021-06-18
📍 Dublin
NCT04895358 on ClinicalTrials.gov ↗
Active Phase 3
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients
Diffuse Large B-cell Lymphoma
Incyte Corporation · started 2021-05-11
📍 Dublin · Limerick
NCT04824092 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC · started 2021-04-14
📍 Dublin
NCT04736706 on ClinicalTrials.gov ↗
Recruiting
FEmale Metabolic Risk and Androgens: an Irish Longitudinal (FEMAIL) Study
Hyperandrogenism, Metabolic Disease, Sex Hormones Adverse Reaction
Royal College of Surgeons, Ireland · started 2021-04-01
📍 Dublin
NCT04912648 on ClinicalTrials.gov ↗
Recruiting
Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy
Breast Cancer, Sentinel Lymph Node, Neoplasm, Breast
University Hospitals of Derby and Burton NHS Foundation Trust · started 2021-02-26
📍 Dublin · Galway
NCT04109079 on ClinicalTrials.gov ↗
Active Phase 3
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
Myeloproliferative Disorders, Myelofibrosis, Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis
Celgene · started 2021-02-25
📍 Cork · Dublin
NCT04717414 on ClinicalTrials.gov ↗
Active Phase 3
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors
Paroxysmal Nocturnal Hemoglobinuria
Hoffmann-La Roche · started 2020-09-30
📍 Dublin
NCT04432584 on ClinicalTrials.gov ↗
Active Phase 2
Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study
Anatomic Stage IV Breast Cancer AJCC v8, Hormone Receptor Positive Breast Carcinoma, Metastatic Breast Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8
ECOG-ACRIN Cancer Research Group · started 2020-09-15
📍 Cork
NCT04316117 on ClinicalTrials.gov ↗
Active Phase 4
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)
Cystic Fibrosis, Cystic Fibrosis Liver Disease, Cystic Fibrosis in Children, Adherence, Medication
Royal College of Surgeons, Ireland · started 2020-09-03
📍 Dublin · Limerick · Tallaght
NCT04602468 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
Colorectal Cancer, Pancreatic Cancer, Gastric Cancers, Cholangiocarcinoma
Bold Therapeutics, Inc. · started 2020-08-28
📍 Dublin
NCT04421820 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors
Select Advanced Solid Tumors
Immunocore Ltd · started 2020-02-25
📍 Dublin
NCT04262466 on ClinicalTrials.gov ↗
Active
Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS)
Queen's University, Belfast · started 2019-11-22
📍 Dublin
NCT04009330 on ClinicalTrials.gov ↗
Recruiting Phase 3
International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma
Lymphoblastic Lymphoma, Childhood
University Hospital Muenster · started 2019-08-23
📍 Dublin
NCT04043494 on ClinicalTrials.gov ↗
Active Phase 3
Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)
Urinary Bladder Cancer, Muscle-invasive
Merck Sharp & Dohme LLC · started 2019-07-24
📍 Dublin · Waterford
NCT03924895 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy
Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2
Stichting Hemato-Oncologie voor Volwassenen Nederland · started 2019-03-01
📍 Cork · Dublin · Galway
NCT03839771 on ClinicalTrials.gov ↗
Active Phase 3
Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX
Hemophilia
Genzyme, a Sanofi Company · started 2019-01-09
📍 Crumlin · Dublin
NCT03754790 on ClinicalTrials.gov ↗
Active
The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
Hypertension, Vascular Diseases, Cardiovascular Diseases
ReCor Medical, Inc. · started 2018-12-14
📍 Galway
NCT03614260 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Astellas Pharma Global Development, Inc. · started 2018-11-28
📍 Dublin
NCT03653507 on ClinicalTrials.gov ↗
Recruiting Phase 3
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Solid Tumors, Hematologic Malignancies
Merck Sharp & Dohme LLC · started 2018-08-21
📍 Dublin
NCT03486873 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
Atopic Dermatitis
AbbVie · started 2018-08-09
📍 Dublin · Cork · Waterford
NCT03568318 on ClinicalTrials.gov ↗
Active Phase 2/Phase 3
International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
Brain Tumors
Universitätsklinikum Hamburg-Eppendorf · started 2014-06
📍 Dublin
NCT02066220 on ClinicalTrials.gov ↗
Active Phase 3
Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer
Prostatic Neoplasms
University of Sydney · started 2014-03
📍 Beaumont · Dublin · Galway · Tallaght · Waterford
NCT02446405 on ClinicalTrials.gov ↗
Recruiting
Lysosomal Acid Lipase (LAL) Deficiency Registry
Lysosomal Acid Lipase Deficiency, Cholesterol Ester Storage Disease, Wolman Disease, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2
Alexion Pharmaceuticals, Inc. · started 2013-05-30
📍 Dublin
NCT01633489 on ClinicalTrials.gov ↗
Recruiting
Pharmacokinetics of Antiretroviral Agents in HIV-infected Pregnant Women.
HIV Infections
Radboud University Medical Center · started 2009-02
📍 Dublin
NCT00825929 on ClinicalTrials.gov ↗
Active Phase 3
Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
Breast Adenocarcinoma, Hormone Receptor Positive, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7
National Cancer Institute (NCI) · started 2006-04-07
📍 Cork · Dublin · Mount Merrion · Galway · Limerick · Sligo
NCT00310180 on ClinicalTrials.gov ↗
By invitation
EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV
HIV, Hepatitis B, Hepatitis C, AIDS
Rigshospitalet, Denmark · started 1994-01
📍 Dublin
NCT02699736 on ClinicalTrials.gov ↗
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Priya Life Science (2026). Clinical Trials in Ireland Tracker. Available at: https://priyalifescience.com/clinical-trials-ireland (Accessed: 20 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — studies listing at least one Irish site, refreshed daily. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. For trials across the wider EU, see our EU Clinical Trials Tracker.