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Compound · clinical trials

Elacestrant

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 8 trials in our USA, UK, China and Ireland registers that name Elacestrant as an intervention. Synced 24 Sep 2026
8Trials tracked
6Recruiting now
4Lead sponsors
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Elacestrant is named as a drug or biological intervention in 8 clinical trials in our USA, UK, China and Ireland trial registers, 6 of which are recruiting. Lead sponsors include Stemline Therapeutics, Inc. (5), European Organisation for Research and Treatment of Cancer - EORTC (1) and Ellipses Pharma (1). Registered phases: Phase 1/2, Phase 3, Phase 1 and Phase 2. Conditions studied include Metastatic Breast Cancer; Breast Cancer; Advanced Breast Cancer.

01

Clinical trials of Elacestrant

8 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT05512364 Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) (ClinicalTrials.gov ↗)
ER-positive Breast Cancer, HER2-negative Breast Cancer, Stage IIB Breast Cancer
Phase 3 Recruiting European Organisation for Research and Treatment of Cancer - EORTC Ireland
NCT06492616 A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Breast Cancer
Phase 3 Recruiting Stemline Therapeutics, Inc. UK, USA, China
NCT05386108 Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer (ClinicalTrials.gov ↗)
Breast Neoplasms, Brain Neoplasms, Neoplasms by Site
Phase 1/2 Recruiting Stemline Therapeutics, Inc. UK, USA
NCT05573126 Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer (ClinicalTrials.gov ↗)
Hormone Receptor-positive Breast Cancer, Hormone Receptor Positive HER-2 Negative Breast Cancer, Metastatic Breast Cancer
Phase 1/2 Recruiting Ellipses Pharma UK, USA
NCT06120283 BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors (ClinicalTrials.gov ↗)
Advanced Solid Tumor, Advanced Breast Cancer, Metastatic Breast Cancer
Phase 1 Recruiting BeOne Medicines USA, China
NCT06638307 A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer (ClinicalTrials.gov ↗)
Advanced Breast Cancer
Phase 1 Recruiting Stemline Therapeutics, Inc. USA
NCT05596409 ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study (ClinicalTrials.gov ↗)
Metastatic Breast Cancer
Phase 2 Active, closed Stemline Therapeutics, Inc. USA
NCT05563220 Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
Breast Cancer, Metastatic Breast Cancer
Phase 1/2 Active, closed Stemline Therapeutics, Inc. UK, USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

15 conditions
Condition (as registered)Trials
Metastatic Breast Cancer4
Breast Cancer2
Advanced Breast Cancer2
ER-positive Breast Cancer1
HER2-negative Breast Cancer1
Stage IIB Breast Cancer1
Stage III Breast Cancer1
Breast Neoplasms1
Brain Neoplasms1
Neoplasms by Site1
Neoplasms1
Hormone Receptor-positive Breast Cancer1
Hormone Receptor Positive HER-2 Negative Breast Cancer1
Advanced Solid Tumor1
Hormone-receptor-positive Breast Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Stemline Therapeutics, Inc.5
European Organisation for Research and Treatment of Cancer - EORTC1
Ellipses Pharma1
BeOne Medicines1
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Elacestrant works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Elacestrant (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.