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Clinical trial register · Ireland

Studies with an Irish investigative site

Every study on the ClinicalTrials.gov registry that lists a site in Ireland and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 615 matching records held by the registry are in this view. Synced 24 Sep 2026, 03:15 UTC
615
Studies in scope
all four open statuses
321
Recruiting now
open to new participants
180
Lead sponsors
across recruiting studies
37
Irish site locations
across all listed studies
Phase mix of the 321 recruiting studies
Phase 3 96 Not applicable 79 Observational 76 Phase 2 30 Phase 1/2 20 Other 20
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Matches title, registry number, sponsor, intervention and condition.
Recruitment status
Phase
Lead sponsor
Merck Sharp & Dohme LLC 36 Royal College of Surgeons, Ireland 29 University College Dublin 21 AbbVie 20 University College Cork 19
Site location
Dublin 483 Cork 170 Galway 124 Limerick 56 Waterford 51
All 37 locations
Target enrolment
to

Trials in this register

615 of 615 studies
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Status
Study
Lead sponsor
Phase
Enrol
Irish sites
Start
Recruiting
Evaluating the De-Escalation of Surveillance for Patients Who Have Undergone Curative Treatment for Primary Breast Cancer
NCT07616258 Breast Cancer
Royal College of Surgeons, Ireland
Not applicable
560
Beaumont
2025-10-02
Recruiting
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S
Phase 3
1,280
Ballinasloe, Dublin, Letterkenny
2025-10-02
Recruiting
HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
NCT05751044 Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory
Princess Maxima Center for Pediatric Oncology
Phase 1/2
26
Dublin
2025-10-01
Recruiting
HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
NCT05745714 Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory
Princess Maxima Center for Pediatric Oncology
Phase 1/2
26
Dublin
2025-10-01
Recruiting
Prediction of Venous Thrombosis During chemotherapy-the PINPOINT Study
NCT07196020 Venous Thromboembolism, Cancer
University of Dublin, Trinity College
Observational
380
Cork, Dublin
2025-10-01
Recruiting
Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
NCT07204275 Primary Membranous Nephropathy
Vertex Pharmaceuticals Incorporated
Phase 2/3
176
Cork, Dublin, Galway
2025-09-30
Recruiting
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
NCT07106762 Urothelial Cancer
Bristol-Myers Squibb
Phase 2/3
470
Cork, Dublin
2025-09-30
Recruiting
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
NCT06865417 Ulcerative Colitis
Alfasigma S.p.A.
Phase 3
80
Dublin
2025-09-29
Recruiting
Pre-infusion Aerobic Cycling Exercise for CardioRespiratory Fitness in Cancer Patients
NCT07182773 Cancer
University of Dublin, Trinity College
Not applicable
80
Dublin
2025-09-24
Recruiting
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
NCT07115953 Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular
Not applicable
130
Dublin
2025-09-22
Recruiting
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
NCT07023835 Amyotrophic Lateral Sclerosis (ALS)
Zydus Therapeutics Inc.
Phase 2
240
Dublin
2025-09-17
Recruiting
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
NCT07160868 Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
St. James's Hospital, Ireland
Not applicable
80
Dublin
2025-09-01
Recruiting
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
NCT07028827 Myopia
Ocus Innovation Ireland Limited
Phase 3
234
2025-09-01
Active, closed
eHealth Support Tool to Improve Quality of Life in Head and Neck Cancer Survivors
NCT07426874 Head and Neck Cancer (H&N)
Royal College of Surgeons, Ireland
Not applicable
30
Beaumont
2025-09-01
Active, closed
Mindful-Med: the Evaluation of the Mindfulness-based Stress-coping and Burnout Prevention Programme for Medical Interns.
NCT07171697 Stress (Psychology), Burnout, Mindfulness
Royal College of Surgeons, Ireland
Not applicable
24
Dublin
2025-09-01
Recruiting
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
NCT06959524 Coronary Arterial Disease (CAD), de Novo Lesions in Native Coronary Arteries
Boston Scientific Corporation
Not applicable
1,616
Cork, Dublin, Galway
2025-08-21
Recruiting
The Satiety Control Optimization by Nutritional Enhancement Study
NCT07420023 Metabolic Diseases, Type 2 Diabetes, Cardiovascular Disease
University College Cork
Not applicable
24
Cork
2025-08-18
Recruiting
A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer
NCT06523374 Barrett's Esophagus, Esophageal Adenocarcinoma
University Hospital, Antwerp
Not applicable
50
Dublin
2025-08-13
Recruiting
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC)
NCT07099898 Neoplasms, Lung
GlaxoSmithKline
Phase 3
420
Dublin
2025-08-11
Recruiting
Randomised Trial of Dual Device Treatment Involving Drug-coated Balloon Angioplasty and Drug-eluting Stent Implantation Compared to Single Device Treatments in Patients With Diabetes Mellitus
NCT07303439 Diabetes Mellitus, Coronary Arterial Disease (CAD), de Novo Coronary Lesions, De Novo Stenosis
Royal College of Surgeons, Ireland
Not applicable
120
Dublin
2025-08-06
Recruiting
Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy
NCT07075016 Acute Myeloid Leukemia
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
227
Cork, Dublin, Galway
2025-08-05
Recruiting
Comparison of 'Sip Til Send' Regimens Prior to Elective Caesarean Delivery Using Bedside Gastric Ultrasound
NCT07407530 Gastric Emptying, Caesarean Delivery, Pregnancy
The Rotunda Hospital
Not applicable
190
Dublin
2025-08-01
Not yet open
Frailty Intervention in Postoperative Hip Fracture Inpatients
NCT07027241 Hip Fractures (ICD-10 72.01-72.2), Frailty at Older Adults, Strength Training, Resistance Training
Royal College of Surgeons, Ireland
Not applicable
50
Waterford
2025-08-01
Not yet open
Gastric Emptying With Metoclopramide in GLP-1 Agonist Patients Undergoing Elective Surgery
NCT07100691 Pulmonary Aspiration During Anaesthetic Induction, Gastric Emptying Time, Preoperative Risk Assessment, Obesity (Disorder)
Mater Misericordiae University Hospital
Phase 4
80
Dublin
2025-08
Active, closed
A Registry on the FARAVIEW Technology of the OPAL HDx Mapping System When Used With the FARAWAVE NAV Ablation Catheter in the Treatment of Atrial Fibrillation
NCT06808217 Atrial Fibrillation, Pulsed Field Ablation, FARAPULSE
Boston Scientific Corporation
Observational
550
Dublin
2025-07-30
Recruiting
Harmony TPV EMEA PMS
NCT06906926 Severe Pulmonary Valve Regurgitation
Medtronic Cardiovascular
Not applicable
80
Dublin
2025-07-30
Recruiting
EASi-PROTKTโ„ข - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
Boehringer Ingelheim
Phase 3
11,800
Ballinasloe, Dublin, Galway
2025-07-22
Recruiting
Sleep Promoting Properties of a Botanical Extract in a Population Complaining From Non-Restorative Sleep (NRS)
NCT07085819 Non Restorative Sleep, Sleep Disorder (Disorder)
Kerry Group P.L.C
Not applicable
160
Cork
2025-07-15
Recruiting
European Venous Registry
NCT06906250 Deep Venous Disease of the Lower Limbs
IRCCS San Raffaele
Observational
100
Galway
2025-07-05
Recruiting
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
NCT06863272 Castration-Resistant Prostatic Cancer, Metastasis
Merck Sharp & Dohme LLC
Phase 1/2
360
Dublin
2025-07-03
Recruiting
RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-IRL)
NCT07095660 Venous Obstruction
Intervene, Inc.
Not applicable
20
Galway
2025-07-02
Recruiting
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
NCT07052903 Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals
Phase 3
1,750
Dublin
2025-07-02
Active, closed
A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD
NCT06981078 Chronic Obstructive Pulmonary Disease
Upstream Bio Inc.
Phase 2
666
Dublin, Tallaght, Drogheda
2025-07-02
Active, closed
Safety Study of Viaskinยฎ Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)
NCT07003919 Allergy, Peanut Allergy
DBV Technologies
Phase 3
480
Cork, Dublin
2025-06-24
Active, closed
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab
NCT06880744 Ulcerative Colitis
AbbVie
Phase 3
573
Ballinasloe, Drogheda, Mullingar, Dublin
2025-06-17
Recruiting
A Phase 2 Study of Mutant-selective PI3Kฮฑ Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
NCT06789913 PIK3CA-Related Overgrowth Spectrum (PROS), Lymphatic Malformations, Vascular Malformations, PIK3CA Mutation
Relay Therapeutics, Inc.
Phase 2
277
Dublin
2025-06-13
Recruiting
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
NCT06943872 Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
BeOne Medicines
Phase 3
630
Dublin, Galway, Limerick
2025-06-11
Recruiting
A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia
NCT06953583 Friedreich Ataxia
Biogen
Phase 3
255
Dublin
2025-06-09
Recruiting
Spyral InSight Study
NCT07013929 Hypertension, Vascular Diseases, Cardiovascular Diseases
Medtronic Vascular
Not applicable
19
Galway
2025-06-09
Recruiting
The AIRTIVITYโ„ข Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
NCT06872892 Bronchiectasis
Boehringer Ingelheim
Phase 3
1,755
Cork, Dublin
2025-06-09
Active, closed
A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy
NCT06821542 Chronic Graft-versus-host-disease
Incyte Corporation
Phase 3
9
Dublin
2025-06-04
Recruiting
SURVEY-CNS: A Feasibility Study of Randomising Women and Men With HER2-Positive Metastatic Breast Cancer to Central Nervous System Surveillance Versus No Surveillance
NCT07503717 Breast Cancer, HER2-Positive Metastatic Breast Cancer
Royal College of Surgeons, Ireland
Not applicable
69
Beaumont
2025-06-01
Recruiting
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
NCT06952504 Endometrial Cancer
Merck Sharp & Dohme LLC
Phase 3
1,123
Dublin, Cork
2025-05-22
Recruiting
Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatment With Efanesoctocog Alfa
NCT06940830 Hemophilia A
Swedish Orphan Biovitrum
Phase 4
250
Dublin
2025-05-21
Recruiting
The Lung Health Check Pilot
NCT07099027 Non-Small Cell Lung Cancer
Royal College of Surgeons, Ireland
Not applicable
2,183
Dublin
2025-05-19
Recruiting
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
NCT06925737 Prostate Cancer, Prostatic Neoplasms
Merck Sharp & Dohme LLC
Phase 3
1,440
Dublin, Cork
2025-05-13
Recruiting
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
NCT06563895 Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies
Eidos Therapeutics, a BridgeBio company
Phase 3
587
Dublin
2025-05-12
Recruiting
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
NCT06499285 Myelodysplastic Syndromes
Takeda
Phase 3
225
Cork, Dublin, Limerick
2025-05-06
Recruiting
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
NCT06881784 NSCLC (Non-small Cell Lung Cancer), Non-Small Cell Lung Cancer, NSCLC, NSCLC (Non-small Cell Lung Carcinoma)
Revolution Medicines, Inc.
Phase 3
590
Cork, Dublin, Galway
2025-05-06
Recruiting
VitaFlow LIBERTY Europe
NCT06535659 Aortic Valve Stenosis
Shanghai MicroPort CardioFlow Medtech Co., Ltd.
Observational
122
Galway
2025-05-06
Recruiting
WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)
NCT06967805 Idiopathic Pulmonary Fibrosis
Mediar Therapeutics
Phase 2
164
Abbotstown, Drogheda, Dublin, Letterkenny
2025-05-05
Recruiting
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
NCT06652438 Acute Myeloid Leukemia, Adult
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
448
Cork, Dublin, Galway, Waterford
2025-05-05
Recruiting
PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis
NCT06855329 Progressive Pulmonary Fibrosis, Interstitial Lung Disease
University of Massachusetts, Worcester
Observational
500
Dublin
2025-05-01
Active, closed
A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)
NCT06924970 Sickle Cell Disease
Agios Pharmaceuticals, Inc.
Phase 2
59
Dublin
2025-05-01
Recruiting
SPYRAL GEMINI Pilot Study
NCT06907147 Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases
Medtronic Vascular
Not applicable
175
Galway
2025-05-01
Recruiting
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
NCT06875310 Carcinoma, Non-Small-Cell Lung
Mirati Therapeutics Inc.
Phase 3
630
Cork, Dublin
2025-04-24
Recruiting
Single vs. Multiple Fraction Trial of Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastases/Progression
NCT05784428 Oligometastatic Disease, Oligoprogression, Toxicity Due to Radiotherapy, Quality of Life
Robert Olson
Not applicable
598
Galway, Dublin, Cork, Waterford
2025-04-16
By invitation
A Study to Learn About the Long-Term Health of Adult Participants From a Previous Study of a New Melanoma Treatment
NCT06848088 Melanoma
Regeneron Pharmaceuticals
Phase 2
48
Dublin
2025-04-14
Recruiting
EXtubation Related Complications - the EXTUBE Study (EXTUBE)
NCT06442930 Extubation
University Health Network, Toronto
Observational
3,000
Castlebar, Cork, Dublin, Galway, Waterford
2025-04-14
Recruiting
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
NCT06890884 Lymphoma, Large B-Cell, Diffuse
Merck Sharp & Dohme LLC
Phase 2
594
Dublin, Limerick
2025-04-11
Recruiting
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
NCT06868277 Carcinoma, Non-Small Cell Lung
AstraZeneca
Phase 3
830
Cork, Dublin, Galway
2025-04-10
Recruiting
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
NCT06824467 Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
Merck Sharp & Dohme LLC
Phase 3
770
Dublin
2025-04-09
Active, closed
Study of Bitopertin in Participants With EPP or XLP (APOLLO)
NCT06910358 Erythropoietic Protoporphyria (EPP), X-Linked Protoporphyria (XLP)
Disc Medicine, Inc
Phase 3
183
Dublin
2025-04-04
Recruiting
A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.
NCT06898450 Advanced Solid Tumors Cancer, MSI-H Cancer
Nimbus Wadjet, Inc.
Phase 1/2
134
Dublin
2025-03-31
Recruiting
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
NCT06750289 Eosinophilic Asthma
AstraZeneca
Phase 3
400
Ballinasloe, Cork, Dublin, Moneymore
2025-03-28
Active, closed
Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)
NCT06726265 Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Immutep S.A.S.
Phase 3
756
Cork, Dublin
2025-03-21
Recruiting
Assessing Intellectual and Motor Outcomes in High-risk Infants
NCT06857539 Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
University College Cork
Observational
600
Cork, Dublin
2025-03-21
Recruiting
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
NCT07032662 Chronic Inflammatory Demyelinating Polyneuropathy
Immunovant Sciences GmbH
Phase 2
162
Waterford
2025-03-18
Active, closed
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
NCT06764485 Metastatic Castration-resistant Prostate Cancer
Celgene
Phase 3
960
Cork, Dublin
2025-03-13
Recruiting
Laparoscopic-Assisted Transversus Abdominus Plane Block Versus Intraperitoneal Irrigation of Local Anesthetic for Patients Undergoing Laparoscopic Cholecystectomy
NCT06714279 Laparoscopic Cholecystectomy, TAP Block, Local Anesthetic
Royal College of Surgeons, Ireland
Phase 1
144
Dublin
2025-03-12
Not yet open
An Educational Intervention to Improve the Success of Intubation in Newborns Using a Video Laryngoscope by Reducing the Time the Procedure Takes.
NCT06898801 Respiratory Distress Syndrome, Newborn, Endotracheal Intubation, Neonatal Intubation Performance, Prematurity
University College Dublin
Not applicable
140
Dublin
2025-03
Recruiting
A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis
NCT07558668 Moderate to Severe Atopic Dermatitis
Sitryx Therapeutics Ltd
Phase 1
149
Dublin
2025-02-26
Recruiting
Inpatient Post-Acute Rehabilitation For Patients in the Midwest: a Prospective Cohort Study of Clinical Characteristics and Process Outcomes
NCT07351526 Rehabilitation, Frailty, Complex Patients in Rehabilitation Phase
University of Limerick
Observational
100
Limerick
2025-02-22
Recruiting
A Prospective Cohort Study of Clinical and Process Outcomes of Older Adults That Transition Through the Geriatric Emergency Medicine Unit(GEM-U)
NCT07237334 Frailty
University of Limerick
Observational
150
Limerick
2025-02-10
Active, closed
A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)
NCT06680817 Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Hoffmann-La Roche
Observational
850
Dublin, Limerick, Waterford
2025-02-05
By invitation
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
NCT06679881 Hereditary Angioedema (HAE)
Pharvaris Netherlands B.V.
Phase 3
170
Dublin
2025-02-01
Not yet open
Burnout and Resilience in Hospital-based Nursing and Medical Personnel and Trainees
NCT06818539 Stress, Burnout
University of Limerick
Observational
650
Limerick
2025-02-01
Recruiting
An Ex-US Study to Assess Treatment Persistence With Risankizumab in Adult Participants With Psoriatic Arthritis
NCT06764693 Psoriatic Arthritis
AbbVie
Observational
1,200
Dublin, Elm Park, Tralee, Cork
2025-01-31
Recruiting
Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial
NCT07209930 Exercise, Healthy Participants, Glucose Variability, Type 1 Diabetes (T1D)
University College Dublin
Not applicable
24
Dublin
2025-01-28
Recruiting
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
NCT06788990 Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
Bicara Therapeutics
Phase 2/3
650
Cork, Dublin
2025-01-28
Recruiting
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
NCT06100289 Ulcerative Colitis, Crohn's Disease
Takeda
Phase 3
70
Dublin
2025-01-22
Recruiting
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
NCT06585774 Chronic Graft-versus-host-disease
Incyte Corporation
Phase 3
240
Dublin
2025-01-21
Active, closed
A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjรถgren's Syndrome
NCT06684847 Primary Sjogrens Disease
argenx
Phase 3
631
Dublin
2025-01-15
Recruiting
A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.
NCT06284317 Non Small Cell Lung Cancer
ETOP IBCSG Partners Foundation
Phase 3
290
Dublin
2025-01-15
Not yet open
Rehab in Mild Stable DCM: Feasibility RCT Comparing Structured Rehabilitation to Clinical Surveillance
NCT06781658 Degenerative Cervical Myelopathy
Royal College of Surgeons, Ireland
Not applicable
24
Dublin
2025-01-13
Recruiting
A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD
NCT06659549 Geographic Atrophy of the Macula
Galimedix Therapeutics Inc
Phase 2
110
Kildare, Waterford
2025-01-10
Active, closed
Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease
NCT06760637 Breast Cancer
Pfizer
Phase 3
1,035
Dublin
2025-01-06
Recruiting
A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease
NCT06227910 Crohn's Disease
Takeda
Phase 3
396
Dublin
2025-01-02
Not yet open
AUGUR-AI - Indocyanine Green Fluorescence Angiography Representer
NCT06708819 Colorectal Surgery, Colorectal Resection, Anastomosis, Surgical, Fluorescence Guided Surgery
Mater Misericordiae University Hospital
Observational
300
Dublin
2025-01
Active, closed
Exoskeleton Training for Spinal Cord Injury Neuropathic Pain (ExSCIP)
NCT06463418 Traumatic Spinal Cord Injury
University College Dublin
Not applicable
40
Dublin
2024-12-20
Recruiting
A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)
NCT06679101 Multiple Myeloma, Newly Diagnosed Multiple Myeloma
GlaxoSmithKline
Phase 3
520
Dublin, Galway, Waterford
2024-12-16
Active, closed
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
NCT06500455 Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma, Metastatic Lung Non-Small Cell Carcinoma
NRG Oncology
Phase 3
274
Dublin, Galway, Cork
2024-12-12
Recruiting
A Clinical Trial to Evaluate Efficacy and Safety of Navepegritide in Adolescents (12 - 18 Years of Age) With Achondroplasia.
NCT06732895 Achondroplasia
Ascendis Pharma A/S
Phase 2
24
Dublin
2024-12-10
Active, closed
Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
NCT06669754 Hereditary Angioedema (HAE)
Pharvaris Netherlands B.V.
Phase 3
81
Dublin
2024-12-01
By invitation
PIECES - Towards Large-Scale Adaptation and Tailored Implementation of Primary Cancer Prevention Programs
NCT06718322 Focus of Study: Tailored Implementation
Hidde van der Ploeg
Not applicable
100
Limerick
2024-12-01
Recruiting
SYMPHONYโ„ข OCT System for Instabilities of the Upper Thoracic and Cervical Spine
NCT06816862 Cervical Instabilities Spine, Spine; Instability
University College Dublin
Observational
35
Dublin
2024-12-01
Active, closed
Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)
NCT06635824 PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC
Genmab
Phase 3
191
Cork, Dublin, Limerick, Waterford
2024-11-25
Recruiting
Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
NCT06820008 Amyotrophic Lateral Sclerosis, Motor Neurone Disease
University of Dublin, Trinity College
Observational
60
Dublin
2024-11-21
Recruiting
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
NCT06690775 Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer, Endometrioid Ovarian Cancer
TORL Biotherapeutics, LLC
Phase 2
230
Dublin
2024-11-20
Active, closed
A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)
NCT06422884 Idiopathic Pulmonary Fibrosis, Progressive Fibrosing Interstitial Lung Disease
Endeavor Biomedicines, Inc.
Phase 2
213
Dublin, Cork
2024-11-15
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Irish investigative site. Derived from ClinicalTrials.gov, U.S. National Library of Medicine. Retrieved 24 September 2026. https://priyalifescience.com/clinical-trials-ireland?page=2

Query this register directly
GET /api/trials?country=ie&status=recruiting&phase=Phase+3&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Ireland and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 615 studies in total at the last sync on 24 Sep 2026, 03:15 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Ireland?

321 of the 615 studies in this register are recruiting new participants as of the 24 Sep 2026, 03:15 UTC sync. A further 26 have not yet opened recruitment, 248 are active but closed to new participants, and 20 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (22) Prostate Cancer (14) Cancer (11) Ulcerative Colitis (11) Multiple Myeloma (10) Crohn's Disease (9) Ovarian Cancer (8) Non-small Cell Lung Cancer (7) Chronic Lymphocytic Leukemia (7) Vascular Diseases (6) Fallopian Tube Cancer (6) Hypertension (6) Cardiovascular Diseases (6) Idiopathic Pulmonary Fibrosis (5) Breast Neoplasms (5)
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Browse trials by site location

Dublin (483) Cork (170) Galway (124) Limerick (56) Waterford (51) Beaumont (13) Sligo (12)
Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. For trials across the wider EU, see the EU Clinical Trials Tracker.