Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact
Priya Life Science Compound trial record
Compound · clinical trials

Truxima clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 31 trials in our Israel, Italy, Canada, USA, Spain, Poland, Australia, China, South Korea, Germany, France, Turkey, Japan, UK, Belgium, Switzerland, Taiwan, Mexico, Austria, Czechia, Ireland, Brazil, Singapore, Netherlands, Portugal, Denmark, Sweden, Norway and Egypt registers that name Truxima as an intervention. Synced 9 Nov 2026
31Current trials
11Recruiting now
18Lead sponsors
29Country registers
At a glance

Truxima is named as an intervention in 31 current clinical trials in our Israel, Italy, Canada, USA, Spain, Poland, Australia, China, South Korea, Germany, France, Turkey, Japan, UK, Belgium, Switzerland, Taiwan, Mexico, Austria, Czechia, Ireland, Brazil, Singapore, Netherlands, Portugal, Denmark, Sweden, Norway and Egypt registers. 11 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is National Cancer Institute (NCI) (8). The most-studied condition is Chronic Lymphocytic Leukemia.

Patient leaflets for Truxima

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting1135%
  • Not yet open26%
  • Active, closed1858%

Trials by phase

  • Phase 31548%
  • Phase 2929%
  • Phase 2/3310%
  • Phase 1/226%
  • Phase 426%
01

Clinical trials of Truxima

31 trials
StudyPhaseStatusLead sponsorRegisters
Tapering of Rituximab Based on Interval Prolongation Compared to Disease Activity-guided Dose Reduction in Patients With Rheumatoid Arthritis
NCT06003283 · ClinicalTrials.gov ↗ · Rheumatoid Arthritis
Phase 4 Recruiting Universitaire Ziekenhuizen KU Leuven Belgium
Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD
NCT07010302 · ClinicalTrials.gov ↗ · NMOSD
Phase 4 Recruiting Massachusetts General Hospital Germany
Non-inferiority Study of Rituximab Compared to Ocrelizumab in Relapsing MS
NCT05834855 · Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Demyelinating Autoimmune Diseases, CNS
Phase 3 Recruiting Amsterdam UMC, location VUmc Netherlands
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
NCT06717347 · Diffuse Large B-Cell Lymphoma
Phase 3 Recruiting Merck Sharp & Dohme LLC USA, China, France, Spain, Italy, Netherlands, Belgium, Denmark, Poland, Switzerland, Portugal, Turkey, Canada, Brazil, Mexico, Japan, South Korea, Taiwan, Singapore, Australia, Israel
A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)
NCT07634471 · Follicular Lymphoma
Phase 2/3 Recruiting Merck Sharp & Dohme LLC USA, China, Spain, Italy, Poland, Turkey, South Korea, Taiwan, Australia, Israel
Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial
NCT05886036 · ClinicalTrials.gov ↗ · Nodular Lymphocyte Predominant B-Cell Lymphoma, Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma, Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma
Phase 2 Recruiting National Cancer Institute (NCI) Canada
Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma
NCT06510309 · ClinicalTrials.gov ↗ · Lymphoma, Marginal Zone Lymphoma, MZL
Phase 2 Recruiting Gottfried von Keudell, MD PhD Israel
BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma
NCT06854003 · ClinicalTrials.gov ↗ · Mantle Cell Lymphoma, Lymphoma
Phase 2 Recruiting Christine Ryan Israel
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
NCT06890884 · Lymphoma, Large B-Cell, Diffuse
Phase 2 Recruiting Merck Sharp & Dohme LLC Ireland, UK, USA, Germany, Italy, Belgium, Poland, Japan, Israel, Egypt
Pembrolizumab, Ibrutinib and Rituximab in PCNSL
NCT04421560 · ClinicalTrials.gov ↗ · Primary Central Nervous System Lymphoma, Recurrent Cancer, Refractory Cancer
Phase 1/2 Recruiting Dana-Farber Cancer Institute Israel
A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas
NCT06090539 · Relapsed/Refractory Non-Hodgkin Lymphoma
Phase 1/2 Recruiting Bristol-Myers Squibb UK, USA, China, Germany, France, Spain, Italy, Netherlands, Switzerland, Turkey, Japan, South Korea
Study of PV in Combination With Bendamustine and Rituximab for Patients With R/R MCL
NCT04913103 · Lymphoma, Mantle-Cell
Phase 2 Not yet open Czech Lymphoma Study Group Czechia
The CARDIOPROTECT Trial
NCT07654426 · ClinicalTrials.gov ↗ · Diffuse Large B-cell Lymphoma (DLBCL), Cardiotoxicity, Lymphoma
Phase 2 Not yet open Beth Israel Deaconess Medical Center Israel
Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia
NCT01886872 · ClinicalTrials.gov ↗ · Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia
Phase 3 Active, closed National Cancer Institute (NCI) Canada, Mexico, Israel
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia
NCT02003222 · ClinicalTrials.gov ↗ · Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Phase 3 Active, closed National Cancer Institute (NCI) Canada, Israel
Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT02048813 · ClinicalTrials.gov ↗ · Anemia, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 3 Active, closed National Cancer Institute (NCI) Mexico, Israel
Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission
NCT03267433 · ClinicalTrials.gov ↗ · Mantle Cell Lymphoma
Phase 3 Active, closed ECOG-ACRIN Cancer Research Group Israel
Study of LOXO-305 (Pirtobrutinib) Versus Investigator's Choice (Idelalisib Plus Rituximab or Bendamustine Plus Rituximab) in Patients With Previously Treated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
NCT04666038 · Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 3 Active, closed Loxo Oncology, Inc Ireland, UK, USA, China, Germany, France, Spain, Italy, Belgium, Poland, Switzerland, Austria, Czechia, Turkey, Canada, Japan, South Korea, Taiwan, Singapore, Australia, Israel
Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma
NCT04759586 · ClinicalTrials.gov ↗ · Primary Mediastinal Large B-Cell Lymphoma
Phase 3 Active, closed National Cancer Institute (NCI) Canada, Australia
A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
NCT04965493 · Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 3 Active, closed Loxo Oncology, Inc Ireland, UK, USA, China, Germany, France, Spain, Italy, Belgium, Sweden, Denmark, Poland, Switzerland, Czechia, Norway, Canada, Japan, South Korea, Taiwan, Singapore, Australia, Israel
A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
NCT05023980 · Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 3 Active, closed Loxo Oncology, Inc UK, USA, China, France, Spain, Italy, Poland, Austria, Czechia, Portugal, Brazil, Japan, South Korea, Taiwan, Australia
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
NCT05100862 · Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
Phase 3 Active, closed BeOne Medicines Ireland, UK, USA, China, Germany, France, Spain, Italy, Belgium, Poland, Switzerland, Austria, Czechia, Portugal, Turkey, Canada, Brazil, Japan, South Korea, Australia, Israel
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
NCT05457556 · ClinicalTrials.gov ↗ · Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia
Phase 3 Active, closed Children's Oncology Group Canada, Australia
Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Experiencing a PMR Relapse
NCT05533164 · ClinicalTrials.gov ↗ · Polymyalgia Rheumatica
Phase 3 Active, closed Sint Maartenskliniek Netherlands
A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)
NCT05624554 · Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 3 Active, closed Merck Sharp & Dohme LLC USA, China, Denmark, Poland, Turkey, Brazil, Mexico, Taiwan, Singapore, Australia
Comparison Between Rituximab Plus Zanubrutinib Versus Rituximab Monotherapy in Untreated SMZL Patients
NCT05735834 · ClinicalTrials.gov ↗ · Splenic Marginal Zone Lymphoma
Phase 3 Active, closed International Extranodal Lymphoma Study Group (IELSG) France, Spain, Italy, Sweden, Switzerland, Austria, Norway
Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas
NCT03984448 · Diffuse Large B-Cell Lymphoma, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Double-Expressor Lymphoma
Phase 2/3 Active, closed National Cancer Institute (NCI) Mexico, Israel
Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma
NCT04799275 · ClinicalTrials.gov ↗ · Ann Arbor Stage III Diffuse Large B-Cell Lymphoma, Ann Arbor Stage IIX (Bulky) Diffuse Large B-Cell Lymphoma, Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma
Phase 2/3 Active, closed National Cancer Institute (NCI) Israel
Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma
NCT01856192 · ClinicalTrials.gov ↗ · Ann Arbor Stage II Diffuse Large B-Cell Lymphoma, Ann Arbor Stage III Diffuse Large B-Cell Lymphoma, Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma
Phase 2 Active, closed National Cancer Institute (NCI) Mexico
Copanlisib and Rituximab in Marginal Zone Lymphoma Patients
NCT03474744 · ClinicalTrials.gov ↗ · Marginal Zone Lymphoma
Phase 2 Active, closed Christian Buske Germany, Austria
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Cyclophosphamide, Doxorubicin, and Prednisone Plus Rituximab or Rituximab Biosimilar (Truxima) (R-CHP) in Participants With Diffuse Large B-Cell Lymphoma (DLBCL) (MK-2140-007)
NCT05406401 · ClinicalTrials.gov ↗ · Lymphoma, Large B-Cell, Diffuse (DLBCL)
Phase 2 Active, closed Merck Sharp & Dohme LLC Spain, Italy, Poland, Turkey, Canada, South Korea, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Truxima

49 conditions
Chronic Lymphocytic Leukemia5Small Lymphocytic Lymphoma5Marginal Zone Lymphoma3Lymphoma3Diffuse Large B-Cell Lymphoma2Acute Lymphoblastic Leukemia2Ann Arbor Stage III Diffuse Large B-Cell Lymphoma2Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma2Mantle Cell Lymphoma2Relapsed/Refractory Follicular Lymphoma1Lymphoma, Large B-Cell, Diffuse1Relapsed/Refractory Non-Hodgkin Lymphoma1
All 49 conditions
Condition (as registered)Trials
Chronic Lymphocytic Leukemia5
Small Lymphocytic Lymphoma5
Marginal Zone Lymphoma3
Lymphoma3
Diffuse Large B-Cell Lymphoma2
Acute Lymphoblastic Leukemia2
Ann Arbor Stage III Diffuse Large B-Cell Lymphoma2
Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma2
Mantle Cell Lymphoma2
Relapsed/Refractory Follicular Lymphoma1
Lymphoma, Large B-Cell, Diffuse1
Relapsed/Refractory Non-Hodgkin Lymphoma1
Follicular Lymphoma1
NMOSD1
Splenic Marginal Zone Lymphoma1
Lymphoma, Large B-Cell, Diffuse (DLBCL)1
Polymyalgia Rheumatica1
Multiple Sclerosis1
Multiple Sclerosis, Relapsing-Remitting1
Demyelinating Autoimmune Diseases, CNS1
Autoimmune Diseases of the Nervous System1
Rheumatoid Arthritis1
Lymphoma, Mantle-Cell1
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative1
Primary Mediastinal Large B-Cell Lymphoma1
Nodular Lymphocyte Predominant B-Cell Lymphoma1
Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma1
Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma1
Stage I Chronic Lymphocytic Leukemia1
Stage II Chronic Lymphocytic Leukemia1
Stage III Chronic Lymphocytic Leukemia1
Stage IV Chronic Lymphocytic Leukemia1
Acute Myeloid Leukemia1
Mixed Phenotype Acute Leukemia1
Myelodysplastic Syndrome1
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified1
Double-Expressor Lymphoma1
EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified1
Anemia1
Ann Arbor Stage II Diffuse Large B-Cell Lymphoma1
Primary Central Nervous System Lymphoma1
Recurrent Cancer1
Refractory Cancer1
Relapsed Cancer1
MZL1
Ann Arbor Stage IIX (Bulky) Diffuse Large B-Cell Lymphoma1
Diffuse Large B-Cell Lymphoma Activated B-Cell Type1
Diffuse Large B-cell Lymphoma (DLBCL)1
Cardiotoxicity1
05

Related compounds

06

Questions about Truxima trials

How many clinical trials are testing Truxima?

31 current trials in our Israel, Italy, Canada, USA, Spain, Poland, Australia, China, South Korea, Germany, France, Turkey, Japan, UK, Belgium, Switzerland, Taiwan, Mexico, Austria, Czechia, Ireland, Brazil, Singapore, Netherlands, Portugal, Denmark, Sweden, Norway and Egypt registers name Truxima as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Truxima trials recruiting patients?

Yes. 11 of the 31 trials are recruiting: 6 with sites in Israel, 4 with sites in Italy, 2 with sites in Canada, 4 with sites in USA, 3 with sites in Spain, 3 with sites in Poland, 2 with sites in Australia, 3 with sites in China, 3 with sites in South Korea, 3 with sites in Germany, 2 with sites in France, 3 with sites in Turkey, 3 with sites in Japan, 2 with sites in UK, 3 with sites in Belgium, 2 with sites in Switzerland, 2 with sites in Taiwan, 1 with sites in Mexico, 1 with sites in Ireland, 1 with sites in Brazil, 1 with sites in Singapore, 3 with sites in Netherlands, 1 with sites in Portugal, 1 with sites in Denmark and 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Truxima clinical trials?

National Cancer Institute (NCI) (8), Merck Sharp & Dohme LLC (5), Loxo Oncology, Inc (3) and BeOne Medicines (1), among 18 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Are there Truxima clinical trials in Ireland?

Yes. 4 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Truxima works or whether it is effective, and it is not medical advice.

Approvals, shortages and trials, every Friday

One email a week with new EMA and FDA approvals, EU and US medicine shortages, how many trials are recruiting in Ireland, and the week's Irish pharma news.

Free. Unsubscribe from any email with one click. See our privacy policy.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Truxima works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Truxima (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.