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Compound · clinical trials

Venclexta clinical trials

Also listed in trial records as Interleukin-11 (IL-11)
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 28 trials in our China, Israel, Australia, USA, Germany, France, UK, Spain, Belgium, Poland, Italy, Netherlands, Denmark, Canada, South Korea, Sweden, Austria, Czechia, Japan, Taiwan, Ireland, Brazil, Turkey, Portugal, Mexico and Egypt registers that name Venclexta as an intervention. Synced 26 Sep 2026
28Current trials
13Recruiting now
20Lead sponsors
26Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Venclexta is named as an intervention in 28 current clinical trials in our China, Israel, Australia, USA, Germany, France, UK, Spain, Belgium, Poland, Italy, Netherlands, Denmark, Canada, South Korea, Sweden, Austria, Czechia, Japan, Taiwan, Ireland, Brazil, Turkey, Portugal, Mexico and Egypt registers. 13 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Dana-Farber Cancer Institute (4). The most-studied condition is Acute Myeloid Leukemia.

Trials by status

  • Recruiting1346%
  • Not yet open14%
  • Active, closed1450%

Trials by phase

  • Phase 21139%
  • Phase 3518%
  • Phase 1/2414%
  • Phase 2/3311%
  • Phase 127%
  • Not applicable27%
  • Phase 414%
01

Clinical trials of Venclexta

28 trials
StudyPhaseStatusLead sponsorRegisters
A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL
NCT05197192 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia
Phase 3 Recruiting German CLL Study Group Germany
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
NCT06943872 · Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 3 Recruiting BeOne Medicines Ireland, UK, USA, China, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Denmark, Poland, Austria, Czechia, Canada, Brazil, Japan, South Korea, Australia, Israel
Acalabrutinib and Venetoclax Treatment of Newly Diagnosed Patients With CLL at High Risk of Infection or Early Treatment
NCT03868722 · ClinicalTrials.gov ↗ · CLL
Phase 2/3 Recruiting Rigshospitalet, Denmark Netherlands, Sweden, Denmark
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
NCT04256317 · ClinicalTrials.gov ↗ · Myelodysplastic Syndromes, Acute Myeloid Leukemia, Myelodysplastic Syndrome/Neoplasm
Phase 2/3 Recruiting Taiho Oncology, Inc UK, USA, Germany, France, Spain, Italy, Poland, Czechia, Canada
AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission
NCT05404906 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia (AML) in Remission
Phase 2/3 Recruiting The First Affiliated Hospital of Soochow University China
REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL)
NCT04523428 · ClinicalTrials.gov ↗ · CLL/SLL
Phase 2 Recruiting Stichting Hemato-Oncologie voor Volwassenen Nederland Netherlands, Belgium, Denmark
Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL
NCT04560322 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Phase 2 Recruiting Massachusetts General Hospital Israel
Zanubrutinib and Venetoclax in CLL (ZANU-VEN)
NCT05168930 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Phase 2 Recruiting Dana-Farber Cancer Institute Israel
Combination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML
NCT06156579 · ClinicalTrials.gov ↗ · AML, MDS
Phase 2 Recruiting University Hospital Tuebingen Germany
Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML
NCT04588922 · ClinicalTrials.gov ↗ · Hematologic Malignancies
Phase 1/2 Recruiting Sellas Life Sciences Group USA, China, Egypt
Avo In R/R And Previously Untreated MCL
NCT04855695 · ClinicalTrials.gov ↗ · Mantle Cell Lymphoma, Refractory Lymphoma
Phase 1/2 Recruiting Austin I Kim Israel
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia
NCT05091424 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Phase 1 Recruiting Hoffmann-La Roche UK, USA, China, Germany, France, Spain, Italy, Poland, South Korea, Australia
Clinical Study Protocol of Maintenance Therapy With Venetoclax in Elderly Patients With AML in First Complete Remission
NCT05909293 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
Not applicable Recruiting The First Affiliated Hospital with Nanjing Medical University China
CLAG+VEN vs CLAG in the Treatment of Relapsed/Refractory AML
NCT06763666 · ClinicalTrials.gov ↗ · Relapsed/Refractory AML
Phase 4 Not yet open Nanfang Hospital, Southern Medical University China
An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
NCT03844048 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, Multiple Myeloma
Phase 3 Active, closed AbbVie Ireland, UK, USA, China, France, Spain, Belgium, Sweden, Denmark, Poland, Austria, Portugal, Turkey, Canada, Mexico, Japan, South Korea, Taiwan, Australia
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome
NCT04401748 · ClinicalTrials.gov ↗ · Myelodysplastic Syndrome (MDS)
Phase 3 Active, closed AbbVie UK, USA, China, Germany, France, Spain, Italy, Netherlands, Belgium, Poland, Austria, Czechia, Turkey, Canada, Brazil, Japan, South Korea, Taiwan, Australia, Israel
Venetoclax + Decitabine vs. "7+3" Induction Chemotherapy in Young AML
NCT05177731 · ClinicalTrials.gov ↗ · AML, Adult, Chemotherapy Effect
Phase 3 Active, closed Chen Suning China
A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
NCT02966756 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Phase 2 Active, closed AbbVie China, Taiwan, Australia
Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL
NCT03580928 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia (CLL)
Phase 2 Active, closed Dana-Farber Cancer Institute Israel
Venetoclax + Azacitidine vs. Induction Chemotherapy in AML
NCT04801797 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
Phase 2 Active, closed Massachusetts General Hospital Israel
Study of Ibrutinib + CD20 Antibody and Venetoclax in Patients With Untreated Mantle Cell Lymphoma
NCT04802590 · ClinicalTrials.gov ↗ · Mantle Cell Lymphoma
Phase 2 Active, closed The Lymphoma Academic Research Organisation France, Belgium
Pirtobrutinib and Venetoclax in Waldenstrรถm Macroglobulinemia
NCT05734495 · ClinicalTrials.gov ↗ · Waldenstrom Macroglobulinemia
Phase 2 Active, closed Dana-Farber Cancer Institute Israel
Genetically Risk-Stratified Venetoclax, Ibrutinib, Rituximab (ยฑ Navitoclax) in Relapsed/Refractory Mantle Cell Lymphoma
NCT05864742 · ClinicalTrials.gov ↗ · Mantle Cell Lymphoma Refractory
Phase 2 Active, closed Peter MacCallum Cancer Centre, Australia Australia
Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFฮฒ::MYH11(+) AML
NCT06429098 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
Phase 2 Active, closed The First Affiliated Hospital of Soochow University China
Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS
NCT03534323 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia, Richter Syndrome
Phase 1/2 Active, closed Dana-Farber Cancer Institute Israel
Study of Lenalidomide, Venetoclax and Obinutuzumab in Patients With Treatment-Naรฏve Follicular Lymphoma
NCT03980171 · ClinicalTrials.gov ↗ · Follicular Lymphoma
Phase 1/2 Active, closed Peter MacCallum Cancer Centre, Australia Australia
Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms
NCT05455294 · ClinicalTrials.gov ↗ · Myeloid Malignancy, Myelodysplastic Syndromes, Myelofibrosis
Phase 1 Active, closed Jacqueline Garcia, MD Israel
Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic Leukemia
NCT07187505 · ClinicalTrials.gov ↗ · Acute Promyelocytic Leukemia (APL)
Not applicable Active, closed Anhui Medical University China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Venclexta

30 conditions
Acute Myeloid Leukemia6Chronic Lymphocytic Leukemia5Chronic Lymphocytic Leukemia (CLL)3Small Lymphocytic Lymphoma2Myelodysplastic Syndromes2Small Lymphocytic Lymphoma (SLL)2Mantle Cell Lymphoma2Multiple Myeloma1Non-Hodgkin's Lymphoma1Myelodysplastic Syndrome/Neoplasm1Chronic Myelomonocytic Leukemia1Myelodysplastic Syndrome (MDS)1
All 30 conditions
Condition (as registered)Trials
Acute Myeloid Leukemia6
Chronic Lymphocytic Leukemia5
Chronic Lymphocytic Leukemia (CLL)3
Small Lymphocytic Lymphoma2
Myelodysplastic Syndromes2
Small Lymphocytic Lymphoma (SLL)2
Mantle Cell Lymphoma2
Multiple Myeloma1
Non-Hodgkin's Lymphoma1
Myelodysplastic Syndrome/Neoplasm1
Chronic Myelomonocytic Leukemia1
Myelodysplastic Syndrome (MDS)1
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma1
Hematologic Malignancies1
AML, Adult1
Chemotherapy Effect1
Acute Promyelocytic Leukemia (APL)1
Acute Myeloid Leukemia (AML) in Remission1
Relapsed/Refractory AML1
AML1
MDS1
CLL/SLL1
CLL1
Mantle Cell Lymphoma Refractory1
Follicular Lymphoma1
Richter Syndrome1
Myeloid Malignancy1
Myelofibrosis1
Waldenstrom Macroglobulinemia1
Refractory Lymphoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Dana-Farber Cancer Institute4
AbbVie3
The First Affiliated Hospital of Soochow University2
Peter MacCallum Cancer Centre, Australia2
Massachusetts General Hospital2
BeOne Medicines1
Taiho Oncology, Inc1
Hoffmann-La Roche1
Sellas Life Sciences Group1
Chen Suning1
Anhui Medical University1
Nanfang Hospital, Southern Medical University1
The First Affiliated Hospital with Nanjing Medical University1
University Hospital Tuebingen1
German CLL Study Group1

+ 5 more sponsors in the trial list above.

04

By country register

RegisterTrialsRecruiting
Clinical trials in China125
Clinical trials in Israel104
Clinical trials in Australia72
Clinical trials in USA64
Clinical trials in Germany65
Clinical trials in France63
Clinical trials in UK53
Clinical trials in Spain53
Clinical trials in Belgium52
Clinical trials in Poland53
Clinical trials in Italy43
Clinical trials in Netherlands43
Clinical trials in Denmark43
Clinical trials in Canada42
Clinical trials in South Korea42
Clinical trials in Sweden32
Clinical trials in Austria31
Clinical trials in Czechia32
Clinical trials in Japan31
Clinical trials in Taiwan30
Clinical trials in Ireland21
Clinical trials in Brazil21
Clinical trials in Turkey20
Clinical trials in Portugal10
Clinical trials in Mexico10
Clinical trials in Egypt11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Venclexta trials

How many clinical trials are testing Venclexta?

28 current trials in our China, Israel, Australia, USA, Germany, France, UK, Spain, Belgium, Poland, Italy, Netherlands, Denmark, Canada, South Korea, Sweden, Austria, Czechia, Japan, Taiwan, Ireland, Brazil, Turkey, Portugal, Mexico and Egypt registers name Venclexta (also registered as Interleukin-11 (IL-11)) as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Venclexta trials recruiting patients?

Yes. 13 of the 28 trials are recruiting: 5 with sites in China, 4 with sites in Israel, 2 with sites in Australia, 4 with sites in USA, 5 with sites in Germany, 3 with sites in France, 3 with sites in UK, 3 with sites in Spain, 2 with sites in Belgium, 3 with sites in Poland, 3 with sites in Italy, 3 with sites in Netherlands, 3 with sites in Denmark, 2 with sites in Canada, 2 with sites in South Korea, 2 with sites in Sweden, 1 with sites in Austria, 2 with sites in Czechia, 1 with sites in Japan, 1 with sites in Ireland, 1 with sites in Brazil and 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Venclexta clinical trials?

Dana-Farber Cancer Institute (4), AbbVie (3), The First Affiliated Hospital of Soochow University (2) and Peter MacCallum Cancer Centre, Australia (2), among 20 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Are there Venclexta clinical trials in Ireland?

Yes. 2 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Venclexta works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Venclexta works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Venclexta (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.