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Trackers› Clinical trials› Portugal
Clinical trial register · Portugal

Clinical Trials in Portugal

Every study on the ClinicalTrials.gov registry that lists a site in Portugal and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 1102 matching records held by the registry are in this view. Synced 11 Nov 2026, 03:18 UTC
1102
Studies in scope
all four open statuses
529
Recruiting now
open to new participants
282
Lead sponsors
across recruiting studies
Top sites
Lisbon 691 Porto 539 Coimbra 254 Braga 184 Vila Nova de Gaia 109
Narrow the register
Recruitment status
Phase
Lead sponsor
Janssen Research & Development, LLC39 Novartis Pharmaceuticals36 Universidade do Porto35 Hoffmann-La Roche33 AbbVie33 AstraZeneca33 Merck Sharp & Dohme LLC30 Boehringer Ingelheim19 Amgen19 University of Coimbra19 Novo Nordisk A/S19 Sanofi18 Bristol-Myers Squibb17 Egas Moniz - Cooperativa de Ensino Superior, CRL16 Bayer14 Eli Lilly and Company13 Daiichi Sankyo13 Aveiro University12 argenx10 GlaxoSmithKline9 University of Minho9 Universidade Nova de Lisboa8 European Organisation for Research and Treatment of Cancer - EORTC8 Association for Innovation and Biomedical Research on Light and Image7 Alnylam Pharmaceuticals7 Fundacao Champalimaud7 Takeda7 Medtronic7 University of Lisbon7 Genmab6 Escola Superior de Tecnologia da Saúde do Porto5 Celgene5 Mirati Therapeutics Inc.5 University of Beira Interior5 University Institute of Maia5 Abbott Medical Devices5 Bioceramed5 Polytechnic Institute of Porto5 Instituto Politécnico de Leiria5 Ionis Pharmaceuticals, Inc.5 Centro Hospitalar de Lisboa Central4 Instituto Valenciano de Infertilidade de Lisboa4 Alexion Pharmaceuticals, Inc.4 Unidade Local de Saúde de Coimbra, EPE4 Clinical Academic Center (2CA-Braga)4 Gilead Sciences4 ViiV Healthcare4 University of Maia4 Faculdade de Motricidade Humana4 Biogen4 University College, London4 ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida4 Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa4 Pfizer4 Lusofona University4 Ipsen4 MicroPort CRM4 Biotronik SE & Co. KG4 Ultragenyx Pharmaceutical Inc4 Implantology Institute3 Gulbenkian Institute for Molecular Medicine3 Insel Gruppe AG, University Hospital Bern3 Inmunotek S.L.3 Xenon Pharmaceuticals Inc.3 European Myeloma Network B.V.3 Vertex Pharmaceuticals Incorporated3 International Extranodal Lymphoma Study Group (IELSG)3 Grupo Lusófona3 Viatris Innovation GmbH3 Fundación EPIC3 Genzyme, a Sanofi Company3 GLSMED Learning Health S.A.3 QED Therapeutics, a BridgeBio company3 Azafaros B.V.3 University of Évora3 University of Trás-os-Montes and Alto Douro3 H. Lundbeck A/S3 Unidade Local de Saúde do Alto Ave, EPE3 Seagen, a wholly owned subsidiary of Pfizer3 Longboard Pharmaceuticals3 Boston Scientific Corporation3 University Hospital, Basel, Switzerland3 Universidade da Coruña2 EyeBiotech Ltd.2 Karuna Therapeutics, Inc., a Bristol Myers Squibb company2 Chugai Pharmaceutical2 Leiden University Medical Center2 MedSIR2 Cytokinetics2 Glycomine, Inc.2 Leica Microsystems (Schweiz) AG2 The Lymphoma Academic Research Organisation2 Stemline Therapeutics, Inc.2 Astellas Pharma Global Development, Inc.2 Unidade Local de Saúde São João, Oporto2 Instituto de Saude Publica da Universidade do Porto2 mAbxience Research S.L.2 UMC Utrecht2 Biohaven Therapeutics Ltd.2 Eidos Therapeutics, a BridgeBio company2 Portuguese Association of Interventional Cardiology2 MoonLake Immunotherapeutics AG2 Region Skane2 Centro Hospitalar De São João, E.P.E.2 University of Milano Bicocca2 Juno Therapeutics, Inc., a Bristol-Myers Squibb Company2 Olema Pharmaceuticals, Inc.2 Exelixis2 Actelion2 IRCCS San Raffaele2 Incyte Corporation2 Hospital Central do Funchal2 Cooperativa de Ensino Superior, Politécnico e Universitário2 Kartos Therapeutics, Inc.2 BeOne Medicines2 Portuguese Oncology Institute, Coimbra2 Euresist Network GEIE2 Loxo Oncology, Inc.2 Eikon Therapeutics2 PharmaMar2 Alliance Foundation Trials, LLC.2 Xeltis2 Weill Medical College of Cornell University2 Harokopio University2 Travere Therapeutics, Inc.2 Hospital do Divino Espírito Santo de Ponta Delgada2 Charite University, Berlin, Germany2 Universitaire Ziekenhuizen KU Leuven2 Celldex Therapeutics2 Instituto Politécnico de Setúbal2 Maria Paço2 Atlantica - Instituto Universitario2 Otsuka Pharmaceutical Development & Commercialization, Inc.2 Jazz Pharmaceuticals2 ADVANCED MARKER DISCOVERY S.L.2 Janssen Pharmaceutica N.V., Belgium2 Medtronic Cardiovascular2 Henrique Sousa1 Intellia Therapeutics1 Repertoire Immune Medicines1 ProbiSearch SL1 Dimerix Bioscience Pty Ltd1 Interlinked AB1 Corcym S.r.l1 Tampere University1 Immunocore Ltd1 National Institute of Oncology, Hungary1 Escola Superior de Saúde Norte da Cruz Vermelha Portuguesa1 Biosense Webster, Inc.1 OHB Neonatology Ltd.1 Ascendis Pharma Growth Disorders A/S1 Marta Sofia Ramos Torres1 Centro Hospitalar Universitario do Algarve1 Nobel Biocare1 Associazione Italiana Ematologia Oncologia Pediatrica1 PedNet Haemophilia Research Foundation1 Blueprint Medicines Corporation1 Indiana University1 Fábio Cota Medeiros1 Eduarda Oliosi, MS1 Universidade Católica Portuguesa1 Celcuity Inc1 Javier P. Gisbert1 Amsterdam UMC, location VUmc1 Vifor Pharma, Inc.1 K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc1 AIRNA Corporation1 Alumis Inc1 Shanghai MicroPort CardioFlow Medtech Co., Ltd.1 Noucor Health S.A.1 Xoft, Inc.1 Industrial Farmacéutica Cantabria, S.A.1 Kedrion S.p.A.1 Liquidia Technologies, Inc.1 Teknimed1 Clinical Hospital Colentina1 Fundación Española de Hematología y Hemoterapía1 Umbria Bioengineering Technologies1 Norgine1 Cyprus Institute of Neurology and Genetics1 Philipp Dutkowski1 Ceric Sàrl1 Tecsam - Tecnologia e Servicos Medicos1 Cough Monitoring Medical Solutions1 Vascutek Ltd.1 Advanced Accelerator Applications1 CSL Behring1 Corbus Pharmaceuticals Inc.1 Hydrumedical1 Universidade do Algarve1 Instituto Politécnico de Bragança1 Contineum Therapeutics1 4D Molecular Therapeutics1 Pedro Morgado1 X4 Pharmaceuticals1 Firalis SA1 Kura Oncology, Inc.1 Santen SAS1 TransThera Sciences (Nanjing), Inc.1 Institut de Recherches Internationales Servier1 Stichting International Registry for Alzheimer's Disease and other Dementias Foundation1 BioGaia AB1 Associação Centro de Apoio Tecnológico Agro Alimentar1 SK Life Science, Inc.1 Kyowa Kirin Pharmaceutical Development Ltd1 Zymeworks BC Inc.1 Geron Corporation1 University Rovira i Virgili1 Corxel Pharmaceuticals1 Gossamer Bio USA, Inc.1 Hospital de Sao Sebastiao1 German Heart Institute1 Montreal Heart Institute1 Insmed Incorporated1 Abivax S.A.1 Portucalense University1 Akcea Therapeutics1 LEO Pharma1 Medtronic Neurovascular Clinical Affairs1 University Hospital Muenster1 ONL Therapeutics1 Acerta Pharma BV1 Inventiva Pharma1 Jules Bordet Institute1 Deciphera Pharmaceuticals, LLC1 University of Birmingham1 P+F Products + Features GmbH1 Z Optics, Inc.1 Immunovant Sciences GmbH1 Local Health Unit Barcelos/Esposende, Public Health Unit1 University Hospital, Toulouse1 CHDI Foundation, Inc.1 Erasmus Medical Center1 Summit Therapeutics1 Meril Life Sciences Pvt. Ltd.1 Hugo César Vicente1 Medtronic Cardiac Ablation Solutions1 Pierre Fabre Medicament1 EP Solutions SA1 SOLTI Breast Cancer Research Group1 Janssen Scientific Affairs, LLC1 Philips Clinical & Medical Affairs Global1 Amicus Therapeutics1 Calico Life Sciences LLC1 Rita Alexandra Afonso da Costa1 University of Leeds1 Policlinic Hospital "G. Rodolico"1 Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea1 Unidade Local De Saúde Do Norte Alentejano1 GT Metabolic Solutions, Inc.1 Sonia Batista1 NeuroDerm Ltd.1 Inari Medical1 Instituto de Investigación Biomédica de Salamanca1 Unidade Local de Saude Sao Jose1 Julius Clinical1 Artur Salgado SA1 CUTISS AG1 Physio-Assist1 Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III1 Albino Maia1 Tectonic Therapeutic1 Vividion Therapeutics, Inc.1 Cláudio da Silva Ferreira1 Institut für Pharmakologie und Präventive Medizin1 University Fernando Pessoa1 Indizen Optical Technologies, S.L.U.1 Instituto Portugues de Oncologia, Francisco Gentil, Porto1 Omniartro Lda1 Hospital de Santa Cruz, Portugal1 Terremoto Biosciences Inc.1 IRCCS Azienda Ospedaliero-Universitaria di Bologna1 VarmX B.V.1 Occlutech International AB1 European Foundation for Study of Chronic Liver Failure1 Genentech, Inc.1 Neurocrine Biosciences1 Faculty of Sports- Research Center in Physical Activity, Health and Leisure1 Alimentiv Inc.1 José Gabriel da Silva Figueiredo1 Pharming Technologies B.V.1 Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.1 General Practitioners Research Institute1 Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD1 Ferrer Internacional S.A.1 European Society of Cardiology1 Xencor, Inc.1 Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany1 Unidade Local de Saude do Nordeste1 Polytechnic University of Santarém1 BioNTech SE1 Princess Maxima Center for Pediatric Oncology1 ULS Viseu Dão Lafões1 L'Oreal1 Ottimo Pharma Limited1 Memorial Sloan Kettering Cancer Center1 Instituto de Ciências Biomédicas Abel Salazar1 MapLight Therapeutics1 Medicenna Therapeutics, Inc.1 Imbria Pharmaceuticals, Inc.1 McMaster University1 European Association of Urology Research Foundation1 Nuvalent Inc.1 ETOP IBCSG Partners Foundation1 Actuate Therapeutics Inc.1 Immutep S.A.S.1 Janssen-Cilag Farmaceutica Ltda.1 Merit Medical Systems, Inc.1 University of Salamanca1 Penumbra Inc.1 United Therapeutics1 Lacer S.A.1 Colorado Prevention Center1 Sunnybrook Health Sciences Centre1 Relay Therapeutics, Inc.1 Ascendis Pharma A/S1 Savara Inc.1 Linkoeping University1 AOP Orphan Pharmaceuticals AG1 Zogenix, Inc.1 Fundació d'investigació Sanitària de les Illes Balears1 Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company1 Biocodex1 Syndax Pharmaceuticals1 Oncorena AB1 Manuel Coelho da Rocha1 Newcastle University1 PedAL BCU, LLC1 Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS1 Vir Biotechnology, Inc.1 University of Mons1 Escola Superior Saúde Fernando Pessoa1 Grifols Therapeutics LLC1 Vedanta Biosciences, Inc.1 Agios Pharmaceuticals, Inc.1 Sword Health, SA1 Puma Biotechnology, Inc.1 Kite, A Gilead Company1 Essilor International1 Medical University of Graz1 Inhibikase Therapeutics1 AB Science1 José Manuel Afonso Moreira1 Sir Mortimer B. Davis - Jewish General Hospital1 University of L'Aquila1 Manuel Monreal1 Zenas BioPharma (USA), LLC1 Calcilytix Therapeutics, Inc., a BridgeBio company1 Centro Medico Teknon1 Cintia Silva Fassarella1 Hospital Garcia de Orta1 Protagonist Therapeutics, Inc.1 Generate Biomedicines1 Limacorporate S.p.a1 UCB Biopharma SRL1 Valvular Heart Disease in Women Registry1 Johnson & Johnson Enterprise Innovation Inc.1 SymBio Pharmaceuticals1 Frank G. Holz1 LifeSprout, Inc.1 Sociedade Portuguesa de Reumatologia1 Fondazione IRCCS Istituto Nazionale dei Tumori, Milano1 National and Kapodistrian University of Athens1 Unidade Local de Saúde Santa Maria1 Fondazione Don Carlo Gnocchi ETS1 Universitätsklinikum Hamburg-Eppendorf1 Prilenia1 Theravance Biopharma1 SECRETO Study Consortium1 Ivan Patrício1 Instituto Portugues Oncologia de Lisboa Francisco Gentil1 Bicara Therapeutics1 Astria Therapeutics, Inc.1 BioProtect1 Joan Sabater-Riera1 University of Ulm1 Anthogyr1 Greenwich LifeSciences, Inc.1 Artiva Biotherapeutics, Inc.1 University of Oxford1 Women's Cancer Study Group GmbH1 Malo Clinic1 PETHEMA Foundation1 AO Innovation Translation Center1 Catharina Ziekenhuis Eindhoven1 Taiho Oncology, Inc.1 Mats Heyman1 Technical University of Lisbon1 Nimbus Wadjet, Inc.1 MedImmune LLC1 Alfasigma S.p.A.1 Medical University of South Carolina1 RHEACELL GmbH & Co. KG1 Medtronic Spinal and Biologics1 Miltenyi Biomedicine GmbH1 Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico1 Janssen-Cilag Ltd.1 Mirum Pharmaceuticals, Inc.1 OSE Immunotherapeutics1 eleva GmbH1 Masaryk University1 University of Extremadura1 Centro Hospitalar Universitário de Santo António1 Eske Kvanner Aasvang1 PROCEPT BioRobotics1 Hospital Universitari Vall d'Hebron Research Institute1 University Medical Center Groningen1 Denali Therapeutics Inc.1 Escola Superior de Saúde - Universidade do Algarve1 DMG Dental Material Gesellschaft mbH1 Wissenschaftliches Institut Bethanien e.V1 Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv1 Assistance Publique - Hôpitaux de Paris1 OptymEdge, LLC1 Academisch Ziekenhuis Maastricht1 Copenhagen University Hospital, Rigshospitalet1 ADARx Pharmaceuticals, Inc.1 University Hospital, Gasthuisberg1 University of Michigan1 CytoSorbents, Inc1 Lexicon Pharmaceuticals1 Enrique Rodilla1 EMD Serono Research & Development Institute, Inc.1 Hospital de Braga1
Site location
Lisbon691 Porto539 Coimbra254 Braga184 Vila Nova de Gaia109 Guimarães89 Almada85 Loures68 Matosinhos Municipality51 Aveiro40 Carnaxide36 Santa Maria da Feira34 Amadora27 Faro24 Setúbal23 Vila Real23 Leiria21 Ponte de Lima16 Funchal16 Torres Vedras15 Senhora da Hora15 Viana do Castelo14 Portimão14 Viseu13 Evora10 Covilha10 Maia9 Creixomil9 Alcabideche8 Santarém8 Guarda8 Vila Nova de Famalicão6 Senhora Da Hora, Matosinhos5 Ponta Delgada5 Caparica5 Figueira da Foz Municipality5 Vila Franca de Xira4 Torres Novas3 Beja3 Santa Maria DA Feira3 Madeirã3 Portalegre3 Barcelos3 Lordelo2 Riachos, Torres Novas2 Multiple Locations2 Sintra2 Gaia2 Castelo Branco2 Bragança2 Caldas da Rainha2 Many Locations2 Vila do Conde2 Tomar2 Pragal2 Portugal2 Penafiel2 Barcarena2 Oliveira de Azeméis1 Cascais1 Senhora Da Hor1 Abrantes1 Coimbrã1 Fão1 Cruz Quebrada1 Mirandela1 Alfena1 Canelas-V.N.Gaia1 Carregado1 Oeiras1 Lisboa1 Guilhufe1 Sacavém1 Monte de Caparica1 Seco Portimao Faro1 Tondela1 Guilhufe - Penafiel1 Touguinho1 Rio Maior1 Seixal1 Barreiro1 Costa da Caparica1 Paço de Arcos1 Gandra1 Rua Conceição Fernandes1 Amadora-Lisbon1 Alcabideche, Lisboa1 Amadora, Lisboa1 Fundão1 Capuchos1 Lispon1 Baixa Da Banheira1 Angra do Heroísmo1 Amarante1 Chaves1 Creixomil E Mariz1 VILA NOVA de GAIA Porto1 Porto Covo1
All 98 locations
Target enrolment
to

Trials in this register

1102 of 1102 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in Portugal
Start
Not yet open
Chronic COUGH Management in Interstitial Lung DisEase
NCT06782893Interstitial Lung Disease, Chronic Cough
Aveiro University
Not applicable
60
Aveiro
2027-12-20
Not yet open
Escola Superior de Saúde Norte da Cruz Vermelha Portuguesa
Not applicable
50
Oliveira de Azeméis
2027-02-01
Not yet open
Boehringer Ingelheim
Phase 3
1,500
Aveiro, Braga, Coimbra, Guimarães, Leiria, Lisbon, Porto
2027-01-11
Not yet open
University of Lisbon
Not applicable
237
Lisbon
2027-01-04
Not yet open
Hugo César Vicente
Not applicable
7
Loures
2027-01
Not yet open
Universidade do Porto
Phase 3
70
Porto, Santa Maria da Feira
2027-01
Not yet open
24-hour Clear Liquid Diet vs. Standard Fasting for Upper Gastrointestinal Endoscopy in Patients Taking Agonists of the GLP-1 Receptor
NCT07929233Retained Gastric Content, Delayed Gastric Emptying, Obesity, Type 2 Diabetes Mellitus (DM)
Portuguese Oncology Institute, Coimbra
Not applicable
250
Coimbra
2027-01
Not yet open
Bristol-Myers Squibb
Phase 3
2,380
Vila Nova de Gaia, Lisbon, Loures, Porto
2026-12-16
Not yet open
Boehringer Ingelheim
Phase 3
270
Aveiro, Coimbra, Lisbon
2026-12-14
Not yet open
BioGaia AB
Not applicable
40
Lisbon
2026-12-01
Not yet open
Data-Driven Phenotyping in Heart Failure With Preserved Ejection Fraction
NCT07429396Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction (HFPEF)
Instituto Politécnico de Leiria
Observational
200
Leiria
2026-12-01
Not yet open
Marta Sofia Ramos Torres
Not applicable
68
Vila Nova de Gaia
2026-12
Not yet open
Systematic Intraoperative Cell Salvage in On-Pump Cardiac Surgery Within a Mature Patient Blood Management Programme
NCT07922486Cardiac Surgical Procedures, Blood Transfusion, Anemia, Postoperative Hemorrhage
Aveiro University
Observational
657
Vila Nova de Gaia
2026-12
Not yet open
MAFF-CRT: Reducing Sedentary Behaviour in Children
NCT07523945Sedentary Behaviors, Physical Inactivity, Child Health, Lifestyle (Sedentary Behavior and Physical Activity)
Instituto Politécnico de Setúbal
Not applicable
200
Setúbal
2026-11-30
Not yet open
AbbVie
Phase 3
520
Lisbon, Vila Nova de Gaia, Braga, Porto
2026-11-30
Not yet open
PharmaMar
Phase 1/2
231
Lisbon, Porto
2026-11-12
Not yet open
Instituto Politécnico de Bragança
Not applicable
40
Bragança
2026-11-02
Not yet open
TBLC vs NIVATS in Interstitial Lung Disease
NCT07910448Interstitial Lung Diseases (ILD)
Rita Alexandra Afonso da Costa
Not applicable
74
Porto
2026-11-02
Not yet open
University of Coimbra
Not applicable
200
Coimbra
2026-11-01
Not yet open
Instructor Interpersonal Behaviours in Classical Pilates as a Pathway to Improve Blood Pressure Control and Well-being in Hypertensive Adults
NCT07860437High Blood Pressure (& [Essential Hypertension]), Motivation for Physical Activity, Pilates Method, Interpersonal Communication Competence
Instituto Politécnico de Leiria
Not applicable
96
Tomar
2026-11
Not yet open
Universidade do Porto
Not applicable
24
Porto
2026-10-12
Recruiting
Hoffmann-La Roche
Phase 3
400
Lisbon, Loures
2026-10-06
Not yet open
Acute Autonomic Responses During and After BFR Training
NCT07722403Blood Flow Restriction Exercise, Aging
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
48
Almada
2026-10-05
Not yet open
Integrated Early-CARE for Head & Neck Cancer.
NCT07671573Head & Neck Cancer, Locally Advanced Head and Neck Cancer, Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
Portuguese Oncology Institute, Coimbra
Not applicable
64
Coimbra
2026-10-01
Recruiting
Primary Palliative Care - a Feasibility Cluster Trial
NCT07737899Palliative Care, Primary Palliative Care, Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD)
University of Coimbra
Not applicable
30
Coimbra
2026-10-01
Not yet open
Osteoporosis & Renal Disease: Research in Primary Health Care Services
NCT07848490Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder
Universidade do Porto
Observational
622
Barcelos
2026-10-01
Not yet open
Community Physical Exercise Program in Chronic Disease
NCT06771024Osteoarthritis Pain, Myocardial Infarction (MI), Hypertension, Dyslipidemia
Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv
Not applicable
150
Faro
2026-10
Recruiting
Corbus Pharmaceuticals Inc.
Phase 3
260
Lisbon, Porto
2026-09-29
Recruiting
Eli Lilly and Company
Phase 3
150
Lisbon, Porto
2026-09-25
Not yet open
Inspiratory Muscle Training During Hemodialysis
NCT07811947Chronic Kidney Disease (Stages 4 and 5), Hemodialysis, Inspiratory Muscle Training
Tecsam - Tecnologia e Servicos Medicos
Not applicable
53
Mirandela
2026-09-20
Recruiting
Vividion Therapeutics, Inc.
Phase 2
140
Coimbra, Lisbon, Porto
2026-09-11
Recruiting
Janssen Research & Development, LLC
Phase 3
1,000
Braga, Lisbon, Porto, Vila Real
2026-09-09
Active, closed
University of Coimbra
Not applicable
150
Coimbra
2026-09-01
Not yet open
Sonia Batista
Not applicable
130
Coimbra
2026-09-01
Recruiting
Charite University, Berlin, Germany
Phase 3
750
Lisbon
2026-09-01
Not yet open
Aveiro University
Not applicable
46
Aveiro
2026-09-01
Not yet open
CanCOG®: Pilot Trial of Cognitive Rehabilitation for Cancer Survivors
NCT07755839Cancer-related Cognitive Impairment, Cancer-related Cognitive Dysfunction, Cancer-related Cognitive Difficulties, Depression and Anxiety Symptoms
Aveiro University
Not applicable
60
Aveiro
2026-09
Not yet open
Escola Superior de Tecnologia da Saúde do Porto
Not applicable
43
Porto
2026-09
Not yet open
Family-centred Pulmonary Rehabilitation to Empower Carers
NCT07791147Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial, Asthma, Lung Neoplasms
Aveiro University
Not applicable
120
Aveiro, Santa Maria da Feira, Figueira da Foz Municipality, Lisbon, Matosinhos Municipality, Vila Nova de Gaia
2026-09
Not yet open
University of Coimbra
Not applicable
60
Coimbra
2026-09
Not yet open
Combined and Aquatic Exercise in Chronic Low Back Pain
NCT07732595Chronic Low-back Pain (cLBP)
University of Beira Interior
Not applicable
90
Covilha
2026-09
Not yet open
Fundacao Champalimaud
Not applicable
30
Lisbon
2026-09
Not yet open
ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Not applicable
60
Lisbon
2026-09
Not yet open
XR2ESILIENCE - XR-Based Resilience Training for Stress and Mental Health in Healthcare Workers
NCT07544498Occupational Stress, Work-Related Stress, Mental Health, Burnout
Medical University of Graz
Not applicable
232
Beja
2026-09
Not yet open
Sociedade Portuguesa de Reumatologia
Not applicable
72
Aveiro, Lisbon, Porto
2026-09
Not yet open
TIVA Mobile Health Intervention for Family Caregivers
NCT07616284Positive Mental Health, Family Caregivers, Mental Health Promotion, Caregiver Burden
Universidade do Porto
Not applicable
80
Porto
2026-09
Recruiting
AstraZeneca
Phase 2
24
Lisbon, Porto
2026-08-31
Recruiting
AstraZeneca
Phase 3
1,072
Braga, Lisbon, Porto
2026-08-31
Active, closed
Physiological and Performance Characteristics of HYROX Athletes
NCT07873840Physical Fitness, Athletic Performance, Body Composition
Atlantica - Instituto Universitario
Observational
66
Barcarena
2026-08-26
Recruiting
Janssen-Cilag Farmaceutica Ltda.
Observational
250
Lisbon
2026-08-25
Active, closed
Resting Metabolic Rate in Bodybuilders Using Performance-Enhancing Drugs
NCT07878052Athlete Assessment, Body Composition
Atlantica - Instituto Universitario
Observational
62
Barcarena
2026-08-25
Not yet open
Universidade do Porto
Not applicable
60
Porto
2026-08-18
Recruiting
VarmX B.V.
Phase 3
800
Porto
2026-08-18
Recruiting
Instituto Portugues Oncologia de Lisboa Francisco Gentil
Not applicable
2,130
Lisbon
2026-08-06
Recruiting
Novo Nordisk A/S
Phase 3
285
Caldas da Rainha, Figueira da Foz Municipality, Leiria, Lisbon, Vila Nova de Gaia
2026-08-04
Recruiting
Innovative Ovarian Cancer Biomarker Assays
NCT07693894Ovarian Cancer
National and Kapodistrian University of Athens
Observational
2,080
Lisbon
2026-08-03
Not yet open
Hospital do Divino Espírito Santo de Ponta Delgada
Phase 3
252
Funchal, Ponta Delgada, Coimbra, Setúbal
2026-08-01
Not yet open
University of Coimbra
Not applicable
53
Coimbra
2026-08
Recruiting
Aveiro University
Not applicable
20
Braga
2026-07-30
Recruiting
Boehringer Ingelheim
Phase 3
448
Almada, Coimbra, Lisbon, Ponte de Lima, Porto
2026-07-27
Recruiting
Boehringer Ingelheim
Phase 3
35
Lisbon
2026-07-21
Recruiting
Novartis Pharmaceuticals
Phase 3
570
Braga
2026-07-16
Recruiting
Boehringer Ingelheim
Phase 3
390
Lisbon, Porto
2026-07-10
Recruiting
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
NCT07690436Transthyretin Amyloid Cardiomyopathy
AstraZeneca
Observational
500
Guimarães, Lisbon
2026-07-08
Recruiting
Universidade do Porto
Not applicable
106
Porto
2026-07-01
Not yet open
Immediate Restoration of a New Implant With High Primary Stability
NCT07498556Dental Implants, Immediate Dental Implant Loading
Universidade do Porto
Not applicable
50
Porto
2026-07-01
Recruiting
Prilenia
Phase 3
400
Coimbra, Lisbon, Porto, Torres Vedras
2026-07-01
Not yet open
Psoas Major Muscle Intervention on Chronic Lumbar Pain in Cleaning Professionals.
NCT07672197Lumbar Pain, Non-specific Low Back Pain (NSLBP)
Escola Superior de Tecnologia da Saúde do Porto
Not applicable
30
Porto
2026-07
Not yet open
Plasma Exchange Half-dose and Extracorporeal Detoxification for ACLF
NCT07593638Acute on Chronic Liver Failure (ACLF)
Unidade Local de Saude do Nordeste
Not applicable
240
Bragança
2026-07
Not yet open
Lacer S.A.
Not applicable
60
Lisbon
2026-07
Not yet open
Evaluation of Calcified Coronary Lesion Preparation With the Naviscore Scoring Balloon
NCT07650578Coronary Arterial Disease (CAD), Calcific Coronary Arteriosclerosis
University of Mons
Not applicable
200
Vila Nova de Gaia
2026-07
Not yet open
Exogenous Progesterone as Ovulation Trigger
NCT07466199Ovulation, Ovarian Function, Assisted Reproductive Treatments, Oocyte Maturation
DrugsVaginal Micronized Progesterone·Cyclogest
Instituto Valenciano de Infertilidade de Lisboa
Phase 4
10
Lisbon
2026-07
Not yet open
Hospital Garcia de Orta
Observational
15
Almada
2026-07
Recruiting
Janssen Research & Development, LLC
Phase 2
230
Braga, Lisbon, Porto, Vila Nova de Gaia
2026-06-30
Recruiting
Safety and Performances of the LINEA Cardiac Pacing Lead Optimized for the Implantation in Interventricular Septum
NCT07342608Bradycardia, Left Bundle Branch Area Pacing, Left Bundle Branch Pacing
MicroPort CRM
Not applicable
450
Coimbra, Lisbon
2026-06-23
Recruiting
PETHEMA Foundation
Phase 2
50
Aveiro, Funchal, Lisbon, Porto
2026-06-12
Recruiting
Cardiovascular Outcomes Registry in Cardiogenic SHOCK (COR-SHOCK)
NCT07597291Cardiogenic Shock Acute, Cardiogenic Shock, Cardiogenic Shock Post Myocardial Infarction
Hospital de Santa Cruz, Portugal
Observational
800
Carnaxide
2026-06-10
Recruiting
Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD
Phase 3
320
Guimarães
2026-06-05
Not yet open
Universidade Nova de Lisboa
Observational
140
Lisbon
2026-06-01
Not yet open
University Fernando Pessoa
Not applicable
120
Porto
2026-06-01
Recruiting
Bayer
Phase 3
117
Coimbra, Carnaxide, Lisbon, Porto
2026-06-01
Not yet open
Escola Superior de Saúde - Universidade do Algarve
Not applicable
352
Faro
2026-06-01
Not yet open
Escola Superior de Tecnologia da Saúde do Porto
Not applicable
30
Porto
2026-06
Not yet open
Escola Superior de Tecnologia da Saúde do Porto
Not applicable
32
Porto
2026-06
Recruiting
BIO|STREAM.CSP CLS
NCT07608822Sinus Node Disease, Atrioventricular Block
Biotronik SE & Co. KG
Observational
150
Coimbra
2026-05-29
Recruiting
BIO|STREAM.CSP Study
NCT07393009Cardiac Pacing, Cardiac Pacemaker, Implantable Cardioverter Defibrillator, Cardiac Resynchronization Therapy Devices
Biotronik SE & Co. KG
Observational
1,000
Coimbra, Lisbon
2026-05-25
Recruiting
Janssen Research & Development, LLC
Phase 3
644
Braga, Lisbon, Portimão, Setúbal
2026-05-23
Recruiting
Janssen Research & Development, LLC
Phase 3
460
Braga, Lisbon, Portimão, Setúbal, Viana do Castelo
2026-05-22
Recruiting
AbbVie
Phase 3
990
Guimarães, Loures, Almada, Lisbon, Porto
2026-05-22
Recruiting
Hoffmann-La Roche
Phase 2/3
650
Amadora-Lisbon, Lisbon, Loures, Matosinhos Municipality, Porto, Vila Nova de Gaia
2026-05-21
Recruiting
Novo Nordisk A/S
Phase 3
2,500
Riachos, Torres Novas, Almada, Caldas da Rainha, Figueira da Foz Municipality, Lisbon, Senhora Da Hora, Matosinhos, Vila do Conde, Vila Nova de Gaia
2026-05-21
Active, closed
Novo Nordisk A/S
Phase 3
985
Almada, Braga, Cascais, Lisbon, Porto, Senhora Da Hora, Matosinhos, Vila Nova de Gaia
2026-05-20
Not yet open
Universidade Nova de Lisboa
Not applicable
20
Lisbon
2026-05-20
Recruiting
Sleep and Arterial Function in Hypertensive Patients With Poor Sleep Quality
NCT07789535Hypertension, Poor Sleep Quality, Insomnia, Arterial Stiffness
Unidade Local de Saúde do Alto Ave, EPE
Not applicable
234
Guimarães
2026-05-18
Not yet open
University Institute of Maia
Not applicable
60
Maia
2026-05-14
Recruiting
Ipsen
Phase 3
350
Lisbon, Porto, Coimbra
2026-05-14
Active, closed
Novartis Pharmaceuticals
Phase 3
5,700
Coimbra, Guimarães, Setúbal
2026-05-11
Recruiting
TOUCHminds: Help-seeking in Adolescents With Anxiety
NCT07366580Anxiety Symptoms, Anxiety Disorders
Aveiro University
Not applicable
96
Aveiro
2026-05-08
Recruiting
Mirati Therapeutics Inc.
Phase 2
170
Lisbon
2026-05-06
Recruiting
Grifols Therapeutics LLC
Phase 3
40
Guimarães, Loures
2026-05-05
Active, closed
University Rovira i Virgili
Not applicable
108
Porto
2026-05-03
Recruiting
ClusterVAP: Multicentre Proteomic Endotyping of Ventilator-associated Pneumonia
NCT07245888Ventilator Acquired Pneumonia, Mechanical Ventilation Complication
Region Skane
Observational
400
Lisbon
2026-05-01
Recruiting
Polytechnic Institute of Porto
Not applicable
60
Coimbra, Porto
2026-05-01
Recruiting
Aveiro University
Not applicable
12
Amarante
2026-05-01
Not yet open
Study of Hyaluronic Acid Used With Gum Surgery to Treat Gum Recession in Adults
NCT07529340Gingival Recession, Mucogingival Surgery
Universidade do Porto
Not applicable
34
Porto
2026-05
Not yet open
Home Monitoring in eAMD Treatment
NCT07340372Exudative Age-Related Macular Degeneration
DrugAflibercept
Association for Innovation and Biomedical Research on Light and Image
Observational
80
Coimbra, Leiria, Lisbon, Loures, Porto
2026-05
Recruiting
AbbVie
Phase 2/3
900
Lisbon
2026-04-30
Recruiting
Leica Microsystems Sponsored PMCF Study to Collect and Confirm Clinical Data on the Performance of the GLOW400 Device When Used in Accordance With Its Intended Use
NCT07366892Suspected Grade III and IV Gliomas Requiring Surgical Intervention, Neurosurgical Procedure, Glioma, Glioblastoma (GBM)
Leica Microsystems (Schweiz) AG
Observational
37
Porto
2026-04-28
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
NCT07285655Pulmonary Hypertension Due to Lung Disease (Disorder)
Liquidia Technologies, Inc.
Phase 3
344
Almada, Coimbra, Porto
2026-04-23
By invitation
QED Therapeutics, a BridgeBio company
Phase 2
135
Coimbra
2026-04-23
Recruiting
Inhibikase Therapeutics
Phase 3
486
Porto
2026-04-23
Recruiting
Hospital de Sao Sebastiao
Not applicable
72
Santa Maria da Feira
2026-04-20
Recruiting
University of Coimbra
Not applicable
90
Coimbra
2026-04-20
Recruiting
Transcultural Digital Solutions in Phase III Cardiac Rehabilitation
NCT07252856Heart Failure, Myocardial Infarction
Fondazione Don Carlo Gnocchi ETS
Not applicable
306
Lisbon
2026-04-20
Recruiting
Multicenter Cardiac Decision Impact Study in People With Breast Cancer
NCT07703033Breast Cancer, Cardiovascular (CV) Risk, Coronary Artery Calcifications
UMC Utrecht
Not applicable
1,000
Lisbon
2026-04-20
Recruiting
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 3
420
Coimbrã, Lisbon, Porto
2026-04-17
Recruiting
Novo Nordisk A/S
Phase 2
270
Coimbra, Ponte de Lima, Vila do Conde, Vila Nova de Gaia
2026-04-17
Recruiting
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
NCT07496567Macular Degeneration, Age-Related Macular Degeneration, Choroidal Neovascularization, Wet Macular Degeneration
DrugsTiespectus·Eylea·Aflibercept
EyeBiotech Ltd.
Phase 2/3
960
Coimbra
2026-04-15
Recruiting
Inmunotek S.L.
Phase 3
250
Covilha, Portimão, Ponta Delgada, Amadora, Braga, Santarém
2026-04-15
Recruiting
Boehringer Ingelheim
Phase 3
670
Braga, Coimbra, Lisbon, Porto
2026-04-13
Recruiting
PSYCHOPATHY.COMP Program Among Male Prison Inmates With Psychopathy
NCT07481253Antisocial Personality Disorder (ASPD)
University of Coimbra
Not applicable
200
Lisbon
2026-04-06
Recruiting
Faculdade de Motricidade Humana
Observational
40
Cruz Quebrada
2026-04-01
Recruiting
GLSMED Learning Health S.A.
Observational
10,000
Lisbon
2026-04-01
Not yet open
University Hospital, Toulouse
Observational
209
Lisbon
2026-04-01
By invitation
Porcine Derma for Soft Tissue Augmentation Around Implants
NCT07436091Soft Tissue Augmentation Around Dental Implants
Universidade do Porto
Not applicable
15
Porto
2026-04-01
Not yet open
Indizen Optical Technologies, S.L.U.
Observational
180
Braga
2026-04
Not yet open
Combined Exercise Effects in Breast Cancer-related Lymphedema
NCT07365618Breast Cancer-Related Lymphedema
Faculdade de Motricidade Humana
Not applicable
58
Lisbon
2026-04
Recruiting
InRAD Observational Study
NCT07213700Alzheimer's Disease(AD), Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD), Non-Alzheimer Degenerative Dementia
Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
Observational
50,000
Porto
2026-03-30
Recruiting
Unidade Local de Saúde São João, Oporto
Not applicable
32
Porto
2026-03-26
Recruiting
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
NCT07415044Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe
DrugZotemtegrast
Eli Lilly and Company
Phase 2
1,431
Braga, Lisbon, Santa Maria da Feira
2026-03-26
Recruiting
Novartis Pharmaceuticals
Phase 3
770
Lisbon, Porto
2026-03-24
Not yet open
Cláudio da Silva Ferreira
Not applicable
40
Aveiro
2026-03-23
Recruiting
Universidade do Porto
Not applicable
160
Amadora, Lisbon, Porto
2026-03-23
Recruiting
Boehringer Ingelheim
Phase 2
132
Almada, Braga, Lisbon, Loures
2026-03-23
Not yet open
Hospital de Braga
Observational
150
Braga
2026-03-20
Recruiting
Santen SAS
Observational
112
Lisbon
2026-03-19
Recruiting
Evaluation Of The Success Rate of NOVAMag® SHIELD
NCT07533110Alveolar Buccal Bone Dehiscences, Socket Type 3 Subclass B, Socket Type 3 Subclass C
Egas Moniz - Cooperativa de Ensino Superior, CRL
Phase 4
40
Almada
2026-03-19
Recruiting
AIRNA Corporation
Phase 1
54
Matosinhos Municipality
2026-03-17
Recruiting
SymBio Pharmaceuticals
Phase 3
180
Lisbon, Porto
2026-03-17
Not yet open
Wireless Assessment of Respiratory and Circulatory Distress - Europe
NCT07451249Patient Deterioration, Patient Monitoring, Clinical Deterioration
Eske Kvanner Aasvang
Not applicable
1,240
Lisbon
2026-03-16
Recruiting
Polytechnic Institute of Porto
Not applicable
44
Porto
2026-03-15
Active, closed
Sanofi
Phase 3
59
Guimarães, Porto
2026-03-12
Recruiting
Bristol-Myers Squibb
Phase 3
750
Braga, Lisbon
2026-03-12
Recruiting
Hoffmann-La Roche
Phase 2
360
Braga, Coimbra, Lisbon, Santa Maria da Feira
2026-03-10
Active, closed
Aveiro University
Not applicable
4
Aveiro
2026-03-10
Active, closed
Expert Validation of an Autonomous Personalized Physical Activity Algorithm
NCT07475221Experts in Physical Activity Prescription and Risk Health Screening
Polytechnic Institute of Porto
Observational
9
Porto
2026-03-10
Recruiting
Janssen Research & Development, LLC
Phase 3
600
Almada, Lisbon, Ponte de Lima, Porto, Vila Nova de Gaia
2026-03-05
By invitation
Lusofona University
Not applicable
80
Maia
2026-03-04
Recruiting
CARE-CRC: Microbiome Insights and Correlations for Risk and Outcomes in Colorectal Cancer
NCT06734156Colorectal Cancer (CRC), Microbiome, Early Onset Colorectal Cancer
Gulbenkian Institute for Molecular Medicine
Observational
400
Lisbon
2026-03-02
Recruiting
University of Évora
Not applicable
14
Loures
2026-03-02
Recruiting
Unidade Local de Saúde São João, Oporto
Not applicable
20
Lisbon, Porto
2026-03-01
Not yet open
ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Not applicable
246
Lisbon
2026-03-01
Not yet open
Suprascapular Nerve Block to Improve Tolerance and Outcomes of Shoulder Hydrodistension in Adhesive Capsulitis
NCT07380087Adhesive Capsulitis, Adhesive Capsulitis of Unspecified Shoulder, Adhesive Capsulitis, Shoulder, Frozen Shoulder
Universidade do Porto
Not applicable
50
Porto
2026-03-01
Active, closed
Universidade do Porto
Not applicable
60
Porto
2026-03-01
Recruiting
Instituto Politécnico de Leiria
Not applicable
52
Leiria
2026-03-01
Not yet open
Reactive Strength and Dynamic Rebound: A Drop Jump Index Comparison
NCT07475078Physical Performance Parameters
University Institute of Maia
Not applicable
50
Maia
2026-03
Recruiting
Inmunotek S.L.
Phase 3
250
Coimbra, Lisbon, Porto
2026-02-24
By invitation
University of Évora
Not applicable
200
Evora
2026-02-23
Recruiting
Universidade do Porto
Not applicable
60
Porto
2026-02-18
Recruiting
Boehringer Ingelheim
Phase 3
286
Almada, Amadora, Braga, Coimbra, Lisbon, Loures, Porto, Setúbal
2026-02-16
Recruiting
ViiV Healthcare
Phase 2
186
Porto, Vila Nova de Gaia
2026-02-11
Recruiting
Instituto de Investigación Biomédica de Salamanca
Observational
400
2026-02-09
Recruiting
Eli Lilly and Company
Phase 3
300
Braga, Porto, Viana do Castelo, Vila Nova de Gaia
2026-02-05
Recruiting
Alnylam Pharmaceuticals
Phase 3
125
Lisbon, Porto
2026-02-03
Recruiting
UL Smile: A Mobile Health Application to Promote Oral Health in Portuguese Adolescents
NCT07276191Oral Health Care, Oral Health Behavior Change, Oral Health Self-efficacy
University of Lisbon
Not applicable
150
Lisbon
2026-02-02
Active, closed
HRVB for Stress and Anxiety During Dentistry Students' Clinical Transition
NCT07415915Stress (Psychology), Anxiety, Psychological Distress
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
50
Almada
2026-02-01
Not yet open
Evaluating the Impact of In-Situ Simulation on Interprofessional Healthcare Team Training
NCT07346937in Situ Simulation, Simulation in Training Center
Universidade do Porto
Not applicable
108
Matosinhos Municipality, Porto
2026-02
By invitation
University Institute of Maia
Not applicable
30
Maia
2026-02
Recruiting
Bayer
Observational
1,600
Many Locations
2026-01-29
Recruiting
AstraZeneca
Phase 1
32
Lisbon
2026-01-26
Recruiting
AbbVie
Phase 2
165
Loures, Senhora da Hora, Faro
2026-01-23
Recruiting
University of Minho
Not applicable
60
Guimarães
2026-01-22
Recruiting
Eikon Therapeutics
Phase 1/2
160
Lisbon, Loures, Porto
2026-01-20
Recruiting
Boehringer Ingelheim
Phase 3
400
Lisbon, Porto
2026-01-16
Recruiting
German Heart Institute
Not applicable
45
Lisbon
2026-01-15
Recruiting
PERFECT - Portuguese Evolut Registry Studying the Outcomes of Medtronic Evolut™ FX+ TAVI System by Evaluating an Optimal Care Pathway for TAVI
NCT07343674Severe Symptomatic Aortic Stenosis (Defined as New York Heart Association (NYHA) Class ≥ II)
Portuguese Association of Interventional Cardiology
Observational
500
Coimbra, Lisbon, Funchal, Porto, Vila Nova de Gaia, Evora
2026-01-14
Recruiting
Eli Lilly and Company
Phase 3
150
Braga, Matosinhos Municipality, Porto, Viana do Castelo, Vila Nova de Gaia
2026-01-12
Recruiting
Hospital Central do Funchal
Not applicable
110
Funchal
2026-01-12
Recruiting
OptymEdge, LLC
Observational
90
Coimbra, Porto
2026-01-12
Recruiting
Leica Microsystems Sponsored Study to Collect and Confirm Clinical Data on the Performance of the GLOW800 Device When Used in Accordance With Its Intended Use.
NCT07164040Reconstructive Surgical Procedures, Plastic Surgery, Vascular Surgical Procedure, Cerebrovascular Disorder
Leica Microsystems (Schweiz) AG
Observational
31
Porto
2026-01-08
Recruiting
Contineum Therapeutics
Phase 2
324
Lisbon
2026-01-08
Recruiting
Novo Nordisk A/S
Phase 3
460
Porto, Vila Nova de Gaia
2026-01-08
Recruiting
Insmed Incorporated
Phase 3
344
Almada, Lisbon
2026-01-07
Recruiting
Unidade Local de Saúde do Alto Ave, EPE
Phase 2
30
Guimarães
2026-01-05
Active, closed
Effects of Exercise Snacking on Physical Fitness, Cognition, and Pain in Institutionalized Older Adults
NCT07335068Chronic Pain, Cognition Disorders in Old Age, Physical Fitness in Older Adults
Ivan Patrício
Not applicable
75
Lisbon
2026-01-05
Active, closed
Technical University of Lisbon
Not applicable
12
Alcabideche
2026-01-05
Recruiting
Portucalense University
Not applicable
96
Porto
2026-01-02
Active, closed
Unidade Local De Saúde Do Norte Alentejano
Observational
250
Portalegre
2026-01-02
Recruiting
The Exercogs® Study
NCT07530315Dementia
Eduarda Oliosi, MS
Not applicable
150
Sintra
2026-01-01
Not yet open
Effectiveness of the DMHI and OPS Platform in Improving Participant QOL: a Randomised Controlled Trial.
NCT07276451Anxiety, Depression and Quality of Life, Quality of Life
Universidade Nova de Lisboa
Not applicable
82
Lisbon
2026-01-01
Recruiting
THE MYOFASCIAL SYSTEM AND MINIMIZING THE RISK OS INJURY IN SPORT
NCT06895720Sports Injuries, Flexibility, Balance, Jumping Performance
Aveiro University
Not applicable
65
Fão
2026-01-01
Recruiting
ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Not applicable
120
Lisbon
2026-01-01
Recruiting
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
21
Caparica, Almada
2026-01-01
Recruiting
University of Trás-os-Montes and Alto Douro
Not applicable
44
Vila Real
2026-01-01
Recruiting
Comparing XEN®-63 Gel Stent and PRESERFLO® MicroShunt
NCT07359547GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Universitaire Ziekenhuizen KU Leuven
Not applicable
166
Lisbon
2026-01-01
Not yet open
Internet Delivered Therapy for Social Anxiety in Adults
NCT06767878Control Group, Intervention
Grupo Lusófona
Not applicable
62
Lisbon
2026-01
Not yet open
University Institute of Maia
Not applicable
22
Porto
2026-01
Recruiting
mAbxience Research S.L.
Phase 3
632
Funchal, Lisbon
2025-12-29
Recruiting
Norgine
Phase 3
212
Braga, Coimbra, Lisbon, Porto
2025-12-29
Recruiting
European Myeloma Network B.V.
Phase 3
1,000
Coimbra, Lisbon
2025-12-23
Recruiting
Ottimo Pharma Limited
Phase 1/2
170
Lisbon
2025-12-17
Recruiting
An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors
NCT07293754Advanced Malignant Solid Tumor
Repertoire Immune Medicines
Phase 1/2
150
Lisbon
2025-12-12
Recruiting
Fundación EPIC
Observational
960
Amadora, Carnaxide, Coimbra, Faro, Penafiel
2025-12-11
Active, closed
BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF
NCT07181590Paroxysmal AF, Atrial Arrhythmia, Atrial Fibrillation, Persistent Atrial Fibrillation
Abbott Medical Devices
Not applicable
300
Lisbon
2025-12-11
Recruiting
AbbVie
Phase 2/3
490
Guimarães, Loures, Senhora da Hora, Braga, Porto
2025-12-10
Active, closed
Boehringer Ingelheim
Phase 3
135
Coimbra, Lisbon, Porto
2025-12-09
Not yet open
Universidade da Coruña
Not applicable
20
Porto
2025-12-08
Recruiting
Virtual Reality for Recovery After Intensive Care (PICS)
NCT07585500Post-Intensive Care Syndrome (PICS), Critical Illness Recovery, Rehabilitation After Critical Illness, Rehabilitation Exercise of ICU Patients
University of Minho
Not applicable
51
Porto
2025-12-06
Recruiting
Generate Biomedicines
Phase 3
786
Figueira da Foz Municipality, Porto
2025-12-03
Recruiting
Janssen Research & Development, LLC
Phase 3
600
Lisbon, Portimão, Porto, Vila Nova de Gaia
2025-12-03
Recruiting
Bristol-Myers Squibb
Phase 3
650
Coimbra, Guimarães, Lisbon, Senhora da Hora, Torres Vedras
2025-12-02
Recruiting
Tuning in to Kids® for Parents of Preschool-aged Children in Portugal
NCT07350083Parental Emotion Socialization, Parents' Beliefs About and Reactions to Children's Emotions, Parental Emotion Regulation
Lusofona University
Not applicable
152
Lisbon
2025-12-02
Active, closed
University of Beira Interior
Not applicable
56
Covilha
2025-12-02
Recruiting
Egas Moniz - Cooperativa de Ensino Superior, CRL
Early Phase 1
30
Caparica
2025-12-01
Recruiting
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
NCT07638319Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
Egas Moniz - Cooperativa de Ensino Superior, CRL
Early Phase 1
30
Caparica
2025-12-01
Recruiting
Amgen
Phase 3
750
Lisbon, Porto, Vila Nova de Gaia
2025-11-28
Recruiting
Women's Cancer Study Group GmbH
Phase 3
250
Lisbon
2025-11-27
Recruiting
Regional Versus General Anesthesia for Hip Fracture and Postoperative Oxygenation
NCT07309575Hip-fracture, General Anaesthesia, Regional Anaesthesia
University of Lisbon
Observational
102
Lisbon
2025-11-27
Recruiting
AbbVie
Phase 1
285
Lisbon, Porto
2025-11-27
By invitation
Celldex Therapeutics
Phase 3
1,370
Aveiro, Coimbra, Lisbon, Setúbal
2025-11-25
Recruiting
Longitudinal Observational Study of Diabetic Retinopathy Progression in Type 2 Diabetes Patients
NCT07458516Diabetic Retinopathy, Diabetes Mellitus, Type 2, Diabetic Complication, Retinal Disease
Association for Innovation and Biomedical Research on Light and Image
Observational
100
Coimbra
2025-11-24
Recruiting
Hoffmann-La Roche
Phase 3
900
Braga, Coimbra, Funchal, Guimarães, Lisbon, Matosinhos Municipality, Torres Vedras
2025-11-24
Active, closed
Bayer
Phase 2
60
Vila Nova de Gaia, Torres Novas, Lisbon, Porto
2025-11-19
Recruiting
Bayer
Phase 3
111
Coimbra, Lisbon, Carnaxide, Porto
2025-11-19
By invitation
Centro Hospitalar de Lisboa Central
Observational
290
Lisbon
2025-11-19
Recruiting
⁶⁸Ga-FAPI PET/CT for Cardiac Fibrosis in Heart Failure
NCT07296081Myocardial Fibrosis, Heart Failure
University of Coimbra
Observational
30
Coimbra
2025-11-17
Active, closed
Musical Intervention for Dental Anxiety
NCT07240233Dental Anxiety
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
60
Almada
2025-11-17
Recruiting
Incyte Corporation
Phase 3
250
Coimbra, Lisbon, Porto
2025-11-13
Recruiting
Novartis Pharmaceuticals
Phase 3
1,275
Braga, Lisbon, Porto
2025-11-11
Recruiting
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
NCT06990269Geographic Atrophy Secondary to Age-related Macular Degeneration
ADARx Pharmaceuticals, Inc.
Phase 2
240
Coimbra, Porto
2025-11-10
Recruiting
AbbVie
Phase 3
561
Coimbra, Lisbon, Porto
2025-11-05
Recruiting
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
NCT07085767Breast Cancer, Locally Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer
DrugsPalazestrant·Ribociclib·Letrozole
Olema Pharmaceuticals, Inc.
Phase 3
1,000
Coimbra, Lisbon, Porto
2025-11-03
Recruiting
Association for Innovation and Biomedical Research on Light and Image
Observational
1,000
Portugal
2025-11-03
Recruiting
Changes in Oral Health-related Quality of Life (OHRQoL) During Full Arch Implant Treatment
NCT07568249Edentulous Mouth, Quality of Life, Tooth Loss, Oral Health Quality of Life (OHQoL) Was Assessed
Implantology Institute
Observational
100
Lisbon
2025-11-01
By invitation
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
50
Almada
2025-11-01
Recruiting
Bayer
Observational
2,000
Multiple Locations
2025-10-29
Recruiting
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
NCT06659445Geographic Atrophy (GA), Age - Related Macular Degeneration (AMD)
DrugAvacincaptad Pegol
ONL Therapeutics
Phase 2
324
Coimbra, Gaia, Porto
2025-10-28
By invitation
NMES, Exercise, and Glycemic Control in Older Adults With Type 2 Diabetes
NCT06856720Type 2 Diabetes Mellitus, Hyperglycemia Due to Type 2 Diabetes Mellitus, Aging
University of Salamanca
Not applicable
75
Viseu
2025-10-27
Recruiting
Hoffmann-La Roche
Phase 3
600
Braga, Loures, Porto, Vila Nova de Gaia
2025-10-24
Recruiting
Daiichi Sankyo
Phase 3
686
Lisbon, Porto
2025-10-24
Recruiting
Novo Nordisk A/S
Phase 1
30
Porto
2025-10-23
Recruiting
Saccharomyces Boulardii CNCM I-745 in Irritable Bowel Syndrome
NCT07168434IBS (Irritable Bowel Syndrome), IBS-D (Diarrhea-predominant), IBS, Mixed Symptoms
DrugSaccharomyces boulardii
Biocodex
Phase 3
406
Braga, Lisbon
2025-10-22
Recruiting
A Study of ZW251 in Participants With Advanced Solid Tumors
NCT07164313Hepatocellular Carcinoma, Squamous Cell Non-Small Cell Lung Cancer, Germ Cell Tumor
Zymeworks BC Inc.
Phase 1
140
Lisbon, Vila Nova de Gaia
2025-10-21
Active, closed
Mixed Reality vs. Traditional Arthroscopic Simulation
NCT07648056Surgical Education, Clinical Competence
Universidade da Coruña
Not applicable
25
Porto
2025-10-20
Recruiting
A Non-interventional Study of Participants With BPDCN Treated With Chemotherapy
NCT07785180Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Stemline Therapeutics, Inc.
Observational
140
Lisbon
2025-10-17
Recruiting
Eli Lilly and Company
Phase 3
4,500
Lisbon
2025-10-15
Not yet open
Testing a Smart Medication Dispenser (Mobili®) to Help People With Chronic Conditions Take Their Medicine
NCT07175545Dose Administration Aids, Medication Adherence, Polypharmacy, Technology in Health
Lusofona University
Not applicable
96
Lisbon
2025-10-15
Recruiting
Bioceramed
Observational
66
Lisbon
2025-10-06
Not yet open
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
52
Almada
2025-10-06
Recruiting
Imbria Pharmaceuticals, Inc.
Phase 2
165
Guimarães, Lisbon
2025-10-06
Recruiting
Hoffmann-La Roche
Phase 2
12
Braga, Coimbra
2025-10-06
Recruiting
Bioceramed
Observational
66
Lisbon
2025-10-06
Recruiting
Fractal vs Isochronous Cueing in Athletes After ACL Reconstruction
NCT07243535Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Athlete
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
36
Almada
2025-10-03
Recruiting
Janssen Research & Development, LLC
Phase 2/3
1,092
Braga, Guimarães, Lisbon, Loures, Porto
2025-10-03
Not yet open
Better4All Personalized Intervention
NCT06997510Obesity Prevention
Harokopio University
Not applicable
1,022
Lisbon
2025-10-01
Recruiting
Impact of a Tailored Digital Intervention on Sedentary Behaviour and Physical Health in Long-term Cardiac Rehabilitation Patients
NCT07910812Cardiovascular Diseases (CVD), Coronary Disease, Heart Failure, Cardiac Rehabilitation
University of Lisbon
Not applicable
64
Lisbon
2025-10-01
Recruiting
BioNortHealth Project
NCT07833787College Students
Polytechnic Institute of Porto
Observational
1,500
Porto
2025-10-01
Active, closed
Janssen Research & Development, LLC
Phase 3
896
Braga, Guimarães, Lisbon, Loures, Porto, Viana do Castelo
2025-10-01
Recruiting
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Phase 2
50
Lisbon
2025-09-30
Recruiting
Daiichi Sankyo
Phase 3
710
Lisbon
2025-09-30
Recruiting
Alfasigma S.p.A.
Phase 3
80
Braga, Coimbra, Viana do Castelo
2025-09-29
Recruiting
Kura Oncology, Inc.
Phase 3
1,300
Lisbon, Braga
2025-09-26
Recruiting
Mirum Pharmaceuticals, Inc.
Phase 4
230
Coimbra
2025-09-25
Recruiting
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
NCT07109726Breast Cancer, Endometrial Cancer, Ovarian Cancer, Lung Squamous Cell Carcinoma
DrugFulvestrant
Terremoto Biosciences Inc.
Phase 1/2
248
Braga, Lisbon
2025-09-23
Recruiting
Universidade do Porto
Not applicable
42
Porto
2025-09-23
Recruiting
Sanofi
Phase 3
942
Almada, Braga, Guimarães, Matosinhos Municipality, Porto
2025-09-16
Recruiting
Bristol-Myers Squibb
Phase 2/3
600
Lisbon, Coimbra, Porto
2025-09-11
Recruiting
Hydrumedical
Not applicable
134
Aveiro, Guimarães, Lisbon, Viana do Castelo
2025-09-09
Recruiting
Alnylam Pharmaceuticals
Phase 3
11,000
Almada, Baixa Da Banheira, Carnaxide, Coimbra, Creixomil, Leiria, Lisbon, Loures
2025-09-06
Recruiting
Evaluation of the Safety and Performance of the Neocement® Inject P
NCT06973239Bone Defects, Orthopaedic Surgery (30 Minutes or Longer)
Bioceramed
Observational
80
Barcelos
2025-09-05
Recruiting
Evaluation of the Safety and Performance of the Neocement®
NCT06973226Bone Defects, Orthopaedic Surgery (30 Minutes or Longer)
Bioceramed
Observational
80
Barcelos
2025-09-05
Active, closed
Grupo Lusófona
Not applicable
117
Lisbon
2025-09-03
Active, closed
The Most Demanding Match Periods: Should GPS Data be Normalized
NCT07321496Most Demanding Periods, Sport
University of Maia
Observational
50
Maia
2025-09-01
Not yet open
Telerehabilitation of Balance Clinical and Economic Decision Support System
NCT06534164Stroke, Mild Cognitive Impairment, Vestibular Diseases, Long Covid19
University College, London
Not applicable
460
Madeirã
2025-09-01
Recruiting
Cardiac Remodelling Following Endovascular Repair of the Aorta
NCT07415447Cardiac Failure, Aortic Disease
Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Observational
40
Lisbon
2025-09-01
Not yet open
Faculdade de Motricidade Humana
Not applicable
48
Lisbon
2025-09-01
Recruiting
More Health Less Diabetes
NCT07079722Pre-diabetes
Faculdade de Motricidade Humana
Not applicable
90
Lisbon
2025-09-01
Not yet open
Learn to Act - Promoting Mental Health Literacy in Chronic Pain
NCT07040852Chronic Pain, Mental Health, Health Literacy
University of Coimbra
Not applicable
40
Coimbra
2025-09
Not yet open
Tailored Vs. Empirical Helicobacter Pylori Infection Treatment
NCT06200779Helicobacter Pylori Infection
Manuel Coelho da Rocha
Phase 4
160
Porto
2025-09
Recruiting
Relay Therapeutics, Inc.
Phase 3
540
Lisbon, Loures, Matosinhos Municipality
2025-08-26
Recruiting
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
NCT06920004Chronic Inflammatory Demyelinating Polyneuropathy, CIDP, CIDP - Chronic Inflammatory Demyelinating Polyneuropathy
DrugsEmpasiprubart·IVIG
argenx
Phase 3
218
Porto
2025-08-22
Active, closed
Amgen
Phase 3
350
Lisbon, Matosinhos Municipality
2025-08-18
Recruiting
MapLight Therapeutics
Phase 2
300
Torres Vedras
2025-08-15
Recruiting
GlaxoSmithKline
Phase 3
420
Almada, Coimbra, Guimarães, Lisbon
2025-08-11
Recruiting
Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic
NCT05955846Intraocular Lens, Cataract, Presbyopia
Z Optics, Inc.
Not applicable
60
Coimbra, Lisbon
2025-08-07
Recruiting
Association for Innovation and Biomedical Research on Light and Image
Phase 4
120
Coimbra, Leiria, Lisbon, Loures, Porto
2025-08-06
Recruiting
AbbVie
Phase 2/3
854
Braga, Porto
2025-08-03
Recruiting
HOPE Against Cancer Recurrence in HCC
NCT06717919Liver Transplantation, HCC, Oncological Outcomes
Philipp Dutkowski
Phase 4
220
Lisbon
2025-08-01
Recruiting
Unidade Local de Saúde do Alto Ave, EPE
Not applicable
100
Guimarães
2025-07-30
Active, closed
Boehringer Ingelheim
Phase 1
16
Lisbon, Porto
2025-07-29
Active, closed
Amgen
Phase 3
12,800
Braga, Carnaxide, Coimbra, Guimarães, Lisbon, Matosinhos Municipality, Ponte de Lima, Riachos, Torres Novas
2025-07-25
Not yet open
Telerehabilitation Decision Support System: Pilot Testing Protocol
NCT07079787Stroke, Mild Cognitive Impairment (MCI), Vestibular Disease, Long Covid-19
University College, London
Not applicable
30
Madeirã
2025-07-25
Recruiting
Celcuity Inc
Phase 3
1,180
Coimbra, Lisbon, Porto
2025-07-24
Recruiting
AbbVie
Phase 1/2
325
Lisbon, Braga, Porto
2025-07-23
Recruiting
4D Molecular Therapeutics
Phase 3
480
Coimbra
2025-07-22
By invitation
Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord Injury
NCT07732868Spinal Cord Injury, Able Bodied, Traumatic Spinal Cord Injuries, Paraplegia, Spinal
José Gabriel da Silva Figueiredo
Not applicable
20
Aveiro, Vila Nova de Gaia
2025-07-22
Recruiting
Boehringer Ingelheim
Phase 3
11,800
Almada, Amadora, Aveiro, Braga, Coimbra, Guimarães, Leiria, Lisbon
2025-07-22
Recruiting
Bristol-Myers Squibb
Phase 3
586
Torres Vedras, Matosinhos Municipality, Braga, Coimbra, Guimarães, Porto
2025-07-21
Recruiting
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
NCT06765109Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
DrugsNeladalkib·Alectinib
Nuvalent Inc.
Phase 3
450
Alcabideche, Lisbon, Porto
2025-07-17
Recruiting
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
NCT06570798Systemic Lupus Erythematosus, Active Refractory Rheumatoid Arthritis
DrugsUplizna·Inebilizumab·Blinatumomab
Amgen
Phase 2
220
Carnaxide, Vila Franca de Xira, Vila Nova de Gaia
2025-07-16
Active, closed
DanceOn50+: Effects of a Dance Program on Physical and Psycho-emotional Health
NCT07158866Physical Activity, Physical Fitness, Well Being
Universidade do Porto
Not applicable
110
Porto
2025-07-15
Active, closed
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 2
89
Lisbon
2025-07-14
Recruiting
Bristol-Myers Squibb
Phase 3
426
Coimbra, Guimarães, Lisbon, Senhora da Hora, Torres Vedras
2025-07-10
Active, closed
Glycomine, Inc.
Phase 2/3
50
Porto
2025-07-09
Recruiting
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
NCT06991114Refractory Rheumatoid Arthritis (RA), Idiopathic Inflammatory Myopathies (IIMs), Systemic Sclerosis (SSc), Rheumatoid Arthritis (RA
Artiva Biotherapeutics, Inc.
Phase 2
90
Vila Nova de Gaia
2025-07-09
Recruiting
Alnylam Pharmaceuticals
Phase 3
1,750
Carnaxide, Creixomil, Leiria, Lisbon, Vila Real, Viseu
2025-07-02
Recruiting
National Institute of Oncology, Hungary
Not applicable
250
Porto
2025-07-01
Not yet open
Empowering Healthy Lifestyle Personalised Intervention to Prevent and Control Obesity: The HealthyW8 Project
NCT07011368Obesity Prevention, Obesity and Overweight, Obesity and Obesity-related Medical Conditions, Digital Health
Fundació d'investigació Sanitària de les Illes Balears
Not applicable
2,720
Coimbra, Evora
2025-07-01
Recruiting
Psilocybin Therapy for Psychological Distress in Palliative Patients
NCT06782724COPD (Chronic Obstructive Pulmonary Disease), ALS (Amyotrophic Lateral Sclerosis), MS (Multiple Sclerosis), Major Depressive Disorder (MDD)
University Medical Center Groningen
Phase 2
108
Lisbon
2025-07-01
Recruiting
MedSIR
Phase 2
200
Lordelo, Alcabideche, Amadora, Aveiro, Braga, Lisbon, Loures, Porto
2025-06-30
Recruiting
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
NCT06966700Breast Neoplasms, Triple Negative Breast Neoplasms, HR Low-Positive/HER2-Negative Breast Neoplasms
DrugsEpirubicin·Adriamycin·Xeloda·Paraplatin
Merck Sharp & Dohme LLC
Phase 3
2,400
Lisbon, Porto
2025-06-30
Active, closed
University of Coimbra
Not applicable
78
Aveiro, Coimbra, Lisbon, Porto
2025-06-30
Recruiting
Azafaros B.V.
Phase 3
72
Porto
2025-06-30
Recruiting
Azafaros B.V.
Phase 3
147
Porto, Lisbon
2025-06-30
Active, closed
Azafaros B.V.
Phase 3
75
Porto, Lisbon
2025-06-30
By invitation
MoonLake Immunotherapeutics AG
Phase 3
835
Lisbon, Porto
2025-06-27
Recruiting
eleva GmbH
Phase 1
39
Lisbon
2025-06-26
Recruiting
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
NCT07037459Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction, Obesity
DrugMaridebart cafraglutide
Amgen
Phase 3
5,056
Almada, Coimbra, Guimarães, Lisbon, Matosinhos Municipality, Porto, Vila Nova de Gaia
2025-06-25
Recruiting
Novartis Pharmaceuticals
Phase 3
400
Braga, Coimbra, Lisbon
2025-06-23
Recruiting
Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease
NCT06410521Peripheral Arterial Disease, Intermittent Claudication
University of Trás-os-Montes and Alto Douro
Not applicable
40
Vila Real
2025-06-20
Recruiting
GlaxoSmithKline
Phase 3
981
Loures, Senhora da Hora, Almada, Guarda, Lisbon, Setúbal, Vila Nova de Gaia
2025-06-20
Recruiting
AI-Driven Model Impact on Patient Engagement in Medically Assisted Reproduction
NCT07087171Infertility (IVF Patients), Artificial Intelligence (AI)
Instituto Valenciano de Infertilidade de Lisboa
Observational
774
Lisbon
2025-06-11
Recruiting
Calico Life Sciences LLC
Phase 2
240
Braga, Faro, Lisbon, Almada, Funchal
2025-06-09
Recruiting
Boehringer Ingelheim
Phase 3
1,755
Aveiro, Braga, Coimbra, Guimarães, Leiria, Lisbon, Porto
2025-06-09
Recruiting
Janssen Research & Development, LLC
Phase 3
600
Lisbon, Porto
2025-06-04
Recruiting
Unidade Local de Saúde de Coimbra, EPE
Not applicable
1,300
Coimbra, Lisbon, Porto
2025-06-04
Active, closed
Incyte Corporation
Phase 3
9
Lisbon, Porto
2025-06-04
Active, closed
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
180
Almada, Seixal, Alcabideche, Amadora, Barreiro, Caparica, Costa da Caparica, Lisbon
2025-06-03
Recruiting
Overweight and Obesity in Adolescents - Sleep Behavioral Intervention
NCT07255274Obesity and Overweight, Sleep Disorder
University of Beira Interior
Not applicable
126
Covilha, Porto
2025-06-03
Recruiting
AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing
NCT07614542Menopause, Gut Microbiome, Hormonal Changes, Chronic Low-Grade Inflammation
Gulbenkian Institute for Molecular Medicine
Observational
300
Lisbon
2025-06-02
Recruiting
Better4All Personalized Intervention Pilot Study
NCT07120802Obesity Prevention
Harokopio University
Not applicable
490
Lisbon
2025-06-01
Active, closed
TrackFrailty Project
NCT06812286Frailty Syndrome
University of Beira Interior
Not applicable
45
Covilha, Fundão
2025-06-01
Recruiting
LDL Cholesterol Reduction Following Ezetimibe Initiation
NCT07839741Atherosclerotic Cardiovascular Disease (ASCVD), Cardiovascular Risk, LDL Cholesterol
DrugEzetimibe
Universidade do Porto
Phase 4
100
Porto
2025-06-01
Recruiting
Mediterranean Diet Intervention for Maternal Postpartum
NCT07038681Postpartum, Cardiometabolic Factors, Cardiac Reverse Remodeling
Universidade do Porto
Not applicable
52
Porto
2025-05-31
Recruiting
Study on Safety and Performance of AdvanCore Bone Void Filler
NCT06736457Bone Fractures, Bone Defects, Bone Loss, Bone Graft
Artur Salgado SA
Not applicable
190
Guimarães, Porto, Tomar, Lordelo
2025-05-29
Active, closed
Merck Sharp & Dohme LLC
Phase 2
160
Lisbon, Porto
2025-05-29
Recruiting
GLSMED Learning Health S.A.
Not applicable
30
Lisbon
2025-05-26
Recruiting
Algorithm-assisted Subjective Refraction Program Dedicated to Children
NCT07046065Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
Essilor International
Not applicable
166
Vila Nova de Famalicão
2025-05-23
Recruiting
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
NCT06901531Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
DrugsZolbetuximab·Adrucil·Capecitabine·Oxaliplatin
Astellas Pharma Global Development, Inc.
Phase 3
500
Almada, Braga, Guimarães, Lisbon, Porto
2025-05-22
Recruiting
Eikon Therapeutics
Phase 2/3
740
Lisbon
2025-05-22
Recruiting
ADVANCED MARKER DISCOVERY S.L.
Not applicable
1,000
Lisbon
2025-05-19
Recruiting
Alexion Pharmaceuticals, Inc.
Phase 3
450
Lisbon, Porto
2025-05-19
By invitation
Universidade do Porto
Observational
850
Porto
2025-05-15
Recruiting
Surgical vs Transcatheter Aortic Valve Replacement in YOUNG Patients
NCT06861361Symptomatic Severe Aortic Stenosis
Ceric Sàrl
Not applicable
1,180
Carnaxide
2025-05-15
Recruiting
Corxel Pharmaceuticals
Phase 2/3
740
Almada, Braga, Faro, Loures, Matosinhos Municipality
2025-05-15
Recruiting
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
40
Almada
2025-05-14
Recruiting
Portuguese Registry With Meril Myval THV Series - MyPORTuVal Registry
NCT06818435Aortic Valve Stenosis, TAVI(Transcatheter Aortic Valve Implantation)
Portuguese Association of Interventional Cardiology
Observational
150
Carnaxide, Coimbra, Evora, Lisbon, Porto
2025-05-13
Recruiting
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
NCT06563895Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies
DrugAcoramidis
Eidos Therapeutics, a BridgeBio company
Phase 3
587
Lisbon, Porto
2025-05-12
Recruiting
Hoffmann-La Roche
Phase 3
425
Braga, Lisbon, Porto, Santa Maria da Feira, Viseu
2025-05-12
Recruiting
Targeting Neurovascular Coupling in Cognitive Decline Via Nitrate-Based Supplementation
NCT07329647Small Vessel Cerebrovascular Disease, Diabete Mellitus
University of Coimbra
Not applicable
25
Coimbra
2025-05-09
Recruiting
Biogen
Phase 3
454
Carnaxide, Vila Nova de Gaia, Aveiro, Braga, Coimbra, Leiria, Setúbal
2025-05-08
Recruiting
VitaFlow LIBERTY Europe
NCT06535659Aortic Valve Stenosis
Shanghai MicroPort CardioFlow Medtech Co., Ltd.
Observational
222
Carnaxide
2025-05-06
Not yet open
Analysis of Muscle Oxygen Saturation and Functional Variables During Physical Capacity Assessments in Patients With COPD
NCT06968273Chronic Obstructive Pulmonary Disease (COPD), Muscle Oxygenation, Exercise, Respiratory Physiotherapy
University of Extremadura
Not applicable
15
Portalegre
2025-05-02
Recruiting
The REMINDER4Care Program for Older Adults Supported by Residential and Daycare Facilities
NCT06922071Dementia Risk Factors, Prevention, Cognitive Health
University of Coimbra
Not applicable
100
Coimbra
2025-05-01
Recruiting
Metabolomics in Subarachnoid Hemorrhage
NCT07865182Subarachnoid Haemorrhage (SAH), Delayed Cerebral Ischemia
Unidade Local de Saude Sao Jose
Observational
100
Lisbon
2025-05-01
Recruiting
Polytechnic Institute of Porto
Not applicable
80
Coimbra, Porto
2025-05-01
By invitation
ESCAPE10: Epidemiology, Risk Factors, and Outcomes of Severe Community-acquired Pneumonia in Elderly Patients Acquired Pneumonia in Elderly Patients
NCT07070284Severe Community-Acquired Pneumonia (sCAP), Elderly Infection, Community-Acquired Infections, Health Care Quality, Access, and Evaluation
Joan Sabater-Riera
Observational
500
Porto
2025-05-01
Not yet open
Sword Health, SA
Not applicable
100
Porto
2025-05
Not yet open
Universidade do Porto
Observational
80
Porto
2025-05
Recruiting
Mirati Therapeutics Inc.
Phase 3
630
Lisbon, Coimbra, Porto
2025-04-24
Recruiting
Polytechnic University of Santarém
Not applicable
250
Braga, Rio Maior, Santarém
2025-04-24
By invitation
QED Therapeutics, a BridgeBio company
Phase 2/3
24
Coimbra
2025-04-22
Active, closed
ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Not applicable
80
Lisbon
2025-04-22
By invitation
INSIDE: Intervention in Nutritional Supplementation to Improve Cognitive Decline in Elderly.
NCT07000500Cognitive Dysfunction, Cognitive Disorder, Dietary Supplements
Maria Paço
Not applicable
50
Vila Nova de Famalicão
2025-04-20
Active, closed
Janssen Research & Development, LLC
Phase 3
752
Guimarães, Leiria, Lisbon, Porto
2025-04-15
Recruiting
AstraZeneca
Phase 3
830
Alcabideche, Braga, Coimbra, Lisbon, Loures, Matosinhos Municipality, Porto
2025-04-10
By invitation
Instituto de Saude Publica da Universidade do Porto
Not applicable
5,700
Vila Nova de Gaia
2025-04-10
Recruiting
Merck Sharp & Dohme LLC
Phase 3
770
Lisbon, Porto
2025-04-09
Recruiting
Bristol-Myers Squibb
Phase 3
194
Braga, Coimbra, Lisbon, Porto
2025-04-08
Recruiting
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
20
Almada
2025-04-08
Recruiting
Vifor Pharma, Inc.
Phase 2
36
Porto
2025-04-06
Active, closed
Escola Superior Saúde Fernando Pessoa
Not applicable
20
Porto
2025-04-04
Recruiting
Inmunotek S.L.
Phase 3
736
Porto, Santarém
2025-04-02
Recruiting
Local Health Unit Barcelos/Esposende, Public Health Unit
Not applicable
1,038
Porto
2025-04-01
Recruiting
University of Coimbra
Not applicable
20
Coimbra
2025-04-01
By invitation
Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP
NCT06859099Polyneuropathy, Inflammatory Demyelinating, Chronic
DrugRiliprubart
Sanofi
Phase 3
300
Lisbon
2025-04-01
Not yet open
Universidade do Porto
Not applicable
50
Porto
2025-04-01
Not yet open
University of Maia
Not applicable
70
Maia
2025-04-01
Not yet open
Universidade do Porto
Phase 1
104
Porto
2025-04
Recruiting
Nimbus Wadjet, Inc.
Phase 1/2
134
Lisbon
2025-03-31
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
683
Lisbon
2025-03-31
Recruiting
AbbVie
Observational
700
Coimbra, Vila Real
2025-03-28
Recruiting
Eli Lilly and Company
Phase 3
700
Coimbra, Lisbon, Porto
2025-03-27
Recruiting
Wissenschaftliches Institut Bethanien e.V
Observational
1,800
Vila Nova de Gaia, Loures
2025-03-24
Active, closed
Immutep S.A.S.
Phase 3
756
Almada, Lisbon, Loures, Porto
2025-03-21
Recruiting
Revised Targets for Knee Radiofrequency Ablation
NCT06934421Osteoarthritis Knee Pain
Centro Hospitalar Universitario do Algarve
Observational
60
Faro, Lisbon
2025-03-20
Active, closed
Astria Therapeutics, Inc.
Phase 3
157
Coimbra, Lisbon
2025-03-20
Active, closed
One-day Mind Programme for Women With Breast Cancer
NCT06852833Breast Cancer Females
University of Coimbra
Not applicable
40
Coimbra
2025-03-19
Recruiting
Immunovant Sciences GmbH
Phase 2
162
Almada, Matosinhos Municipality, Vila Nova de Gaia
2025-03-18
Recruiting
Hoffmann-La Roche
Phase 3
600
Braga, Lisbon, Porto, Santa Maria da Feira, Viseu
2025-03-17
Recruiting
Insel Gruppe AG, University Hospital Bern
Phase 4
906
Amadora, Coimbra, Funchal, Lisbon, Matosinhos Municipality, Porto
2025-03-14
Recruiting
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 3
440
Porto
2025-03-12
Recruiting
Algae Effects in Markers of Cardiovascular Risk and Gut Microbiome
NCT07173062Stroke, Coronary Arterial Disease (CAD), Myocardial Infarction (MI), Diabetes Mellitus
Universidade do Porto
Not applicable
150
Porto
2025-03-11
Recruiting
Inari VISION Registry
NCT06600542Pulmonary Embolism
Inari Medical
Observational
1,000
Lisbon
2025-03-07
Active, closed
Grupo Lusófona
Not applicable
30
Lisbon
2025-03-07
Active, closed
An Ophthalmic Safety Study in Patients With Breast Cancer
NCT06767462Ophthalmic Safety in Patients With Breast Cancer
AstraZeneca
Observational
160
Amadora, Braga
2025-03-05
Active, closed
Bioceramed
Observational
80
Caparica
2025-03-05
Recruiting
Takeda
Phase 3
1,088
Coimbra, Ponte de Lima, Vila Nova de Gaia, Almada, Lisbon
2025-03-03
By invitation
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
NCT06823115Acute Kidney Injury, Fluid Overload, Prematurity Complications, Risk Factors
Indiana University
Observational
8,000
Coimbra, Lisbon, Porto
2025-03-01
Not yet open
Fábio Cota Medeiros
Observational
300
Lisbon
2025-03-01
Not yet open
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
100
Almada
2025-03-01
Recruiting
BCI Training for Social Cognition and Error Monitoring in ASD
NCT06829303Autism Spectrum Disorder (ASD)
University of Coimbra
Not applicable
28
Coimbra
2025-03-01
Not yet open
Universidade do Porto
Not applicable
200
Porto
2025-03-01
By invitation
Heart Pillow - Chemoteraphy
NCT06986213Rehabilitation Program, Breast Cancer Patients
José Manuel Afonso Moreira
Not applicable
60
Evora
2025-03-01
Recruiting
Summit Therapeutics
Phase 3
780
Braga, Lisbon, Porto, Coimbra, Faro
2025-02-27
Recruiting
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Phase 3
339
Lisbon
2025-02-27
Recruiting
Daiichi Sankyo
Phase 3
726
Braga, Guimarães, Lisbon, Porto
2025-02-27
Recruiting
Amgen
Phase 3
844
Lisbon, Ponte de Lima, Vila Nova de Gaia
2025-02-25
Recruiting
AbbVie
Phase 3
420
Lisbon, Almada, Coimbra, Porto
2025-02-13
Active, closed
Sanofi
Phase 3
231
Guimarães, Matosinhos Municipality, Porto, Santa Maria da Feira
2025-02-12
By invitation
Longboard Pharmaceuticals
Phase 3
324
Coimbra, Lisbon, Porto
2025-02-12
Recruiting
Advancing Knowledge in Ischemic Stroke Patients on Oral Anticoagulants
NCT06823466Ischemic Stroke, Oral Anticoagulation, Atrial Fibrillation (AF), Outcome Assessment
University of L'Aquila
Observational
200
Lisbon
2025-02-12
Active, closed
Universidade do Porto
Not applicable
200
Porto
2025-02-10
Active, closed
AbbVie
Phase 3
468
Guimarães, Lisbon, Loures, Senhora da Hora, Almada, Aveiro, Braga, Porto
2025-02-10
Active, closed
Novo Nordisk A/S
Phase 3
400
Senhora Da Hora, Matosinhos, Lisbon, Porto, Vila Nova de Gaia
2025-02-10
Recruiting
LEO Pharma
Phase 3
90
Coimbra, Lisbon, Porto
2025-02-05
Active, closed
A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)
NCT06680817Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
DrugsVabysmo·Faricimab
Hoffmann-La Roche
Observational
875
Coimbra, Lisbon, Porto
2025-02-05
Recruiting
Physio-Assist
Not applicable
468
Braga, Creixomil, Porto
2025-02-03
Not yet open
Universidade Nova de Lisboa
Not applicable
15
Lisbon
2025-02-03
Active, closed
WATER IV Prostate Cancer
NCT06651632Localized Prostate Cancer
PROCEPT BioRobotics
Not applicable
280
Lisbon
2025-02-03
Recruiting
Sir Mortimer B. Davis - Jewish General Hospital
Observational
4,700
Lisbon
2025-02-01
Not yet open
Enrique Rodilla
Not applicable
1,246
Coimbra
2025-02-01
Not yet open
Cooperativa de Ensino Superior, Politécnico e Universitário
Not applicable
60
Vila Nova de Famalicão
2025-02
Not yet open
Cooperativa de Ensino Superior, Politécnico e Universitário
Not applicable
50
Vila Nova de Famalicão
2025-02
Active, closed
Novartis Pharmaceuticals
Phase 3
588
Almada, Braga, Coimbra, Lisbon, Porto
2025-01-31
Not yet open
Universidade do Porto
Not applicable
210
Porto
2025-01-30
Recruiting
Henrique Sousa
Not applicable
60
Maia
2025-01-29
Recruiting
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
NCT06788990Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
DrugsFicerafusp alfa·Keytruda·Pembrolizumab
Bicara Therapeutics
Phase 2/3
650
Braga, Coimbra, Lisbon, Portimão, Porto, Senhora da Hora, Vila Nova de Gaia
2025-01-28
Recruiting
Nutrition-based Interventions to Prevent Cognitive Decline
NCT06853405Cognitive Dysfunction, Cognition Disorder, Memory Disorders, Cognitive Impairment
Instituto de Saude Publica da Universidade do Porto
Not applicable
120
Porto
2025-01-27
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,046
Braga, Lisbon, Porto
2025-01-27
Recruiting
Takeda
Phase 3
70
Coimbra, Lisbon, Porto
2025-01-22
Recruiting
Unidade Local de Saúde de Coimbra, EPE
Not applicable
128
Coimbra
2025-01-16
Active, closed
argenx
Phase 3
631
Coimbra, Lisbon, Ponte de Lima, Vila Nova de Gaia
2025-01-15
Recruiting
Evaluation of PreveCol's Efficiency As a Second Line Method for the Early Colorectal Cancer Detection
NCT06703632Screening for Colon Cancer, Blood Samples, Survey and Questionnaire, Colorectal Carcinoma
ADVANCED MARKER DISCOVERY S.L.
Not applicable
4,538
Lisbon
2025-01-14
Recruiting
UP STUDY - Decipher Persistent Critical Illness Through in Deep Clinical Phenotyping.
NCT07510776Critical Illness, Recovery Outcomes, Critical Care, Intensive Care, Critical Care
Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Observational
7,000
Lisbon, Vila Nova de Gaia
2025-01-13
By invitation
Centro Hospitalar de Lisboa Central
Observational
81
Lisbon
2025-01-08
Active, closed
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
NCT06846541Plaque Psoriasis, Psoriasis (PsO), Psoriasis, Moderate Psoriasis
Alumis Inc
Phase 3
1,680
Guimarães, Lisbon, Porto
2025-01-08
Recruiting
Takeda
Phase 3
396
Coimbra, Lisbon
2025-01-02
By invitation
University of Minho
Not applicable
478
Braga
2025-01-01
By invitation
Unidade Local de Saúde Santa Maria
Observational
180
Lisbon
2025-01-01
Not yet open
Universidade do Porto
Phase 4
50
Porto
2025-01-01
Active, closed
mAbxience Research S.L.
Phase 3
726
Lisbon, Matosinhos Municipality, Porto
2024-12-30
Active, closed
Amgen
Phase 2
61
Braga, Lisbon, Porto
2024-12-26
Recruiting
Clinical Academic Center (2CA-Braga)
Phase 2
70
Braga
2024-12-20
Recruiting
Sanofi
Phase 2
84
Carnaxide, Lisbon, Porto
2024-12-19
Active, closed
argenx
Phase 3
154
Porto
2024-12-18
Recruiting
Janssen Research & Development, LLC
Phase 2
480
Braga, Guimarães, Lisbon, Loures, Porto, Vila Nova de Gaia
2024-12-16
Recruiting
Xeltis
Not applicable
20
Lisbon
2024-12-16
Recruiting
CUTISS AG
Phase 3
70
Coimbra
2024-12-13
Active, closed
Hoffmann-La Roche
Phase 3
350
Braga, Lisbon, Portimão, Porto, Santa Maria da Feira, Viseu
2024-12-11
Recruiting
Novartis Pharmaceuticals
Phase 3
60
Coimbra, Lisbon, Porto
2024-12-09
By invitation
Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)
NCT06723106Antiphospholipid Syndrome (APS), Bullous Pemphigoid (BP), Behçet's Syndrome (BS), Dermatomyositis (DM)
DrugRAY121
Chugai Pharmaceutical
Phase 1
144
Braga, Vila Nova de Gaia
2024-12-09
Recruiting
Centro Hospitalar De São João, E.P.E.
Not applicable
80
Porto
2024-12-05
Active, closed
Janssen Research & Development, LLC
Phase 3
655
Lisbon, Vila Nova de Gaia
2024-12-04
By invitation
A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
NCT06679946Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
DrugVutrisiran
Alnylam Pharmaceuticals
Phase 3
700
Creixomil, Lisbon, Porto, Viseu
2024-12-03
Recruiting
OSE Immunotherapeutics
Phase 3
363
Coimbra, Lisbon, Porto, Vila Nova de Gaia
2024-12-03
Recruiting
Instituto Politécnico de Leiria
Not applicable
57
Leiria
2024-12-02
Active, closed
ViiV Healthcare
Phase 3
326
Porto
2024-12-02
Active, closed
AbbVie
Observational
1,314
Guimarães, Lisbon, Loures, Sintra, Torres Vedras, Coimbra, Porto
2024-11-26
Active, closed
Genmab
Phase 3
191
Coimbra, Matosinhos Municipality, Porto, Setúbal
2024-11-25
Active, closed
Daiichi Sankyo
Phase 3
700
Lisbon, Porto
2024-11-19
Recruiting
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
NCT06369285Hormone Receptor Positive HER-2 Negative Breast Cancer, Metastatic Breast Cancer, Recurrent Breast Cancer
DrugAlisertib
Puma Biotechnology, Inc.
Phase 2
225
Lisbon, Porto
2024-11-19
Recruiting
Eli Lilly and Company
Phase 3
125
Lisbon, Porto
2024-11-18
Active, closed
Longboard Pharmaceuticals
Phase 3
367
Coimbra, Lisbon, Porto
2024-11-11
Active, closed
argenx
Phase 2
87
Lisbon, Vila Nova de Gaia
2024-11-11
Recruiting
Comparison of Two Vaginal Progesterone Forms in Frozen Embryo Transfer
NCT07461909Frozen Embryo Transfer (FET), Infertility, Artificial Cycle, Natural Cycle
Instituto Valenciano de Infertilidade de Lisboa
Observational
400
Lisbon
2024-11-08
Active, closed
University of Trás-os-Montes and Alto Douro
Not applicable
38
Guimarães
2024-11-07
Active, closed
Fundacao Champalimaud
Not applicable
32
Lisbon
2024-11-07
By invitation
Digital Health and Exercise for Autonomous Longevity Program
NCT06722976Mild Cognitive Impairment (MCI), Older People
University of Beira Interior
Not applicable
120
Covilha
2024-11-05
By invitation
Maria Paço
Not applicable
48
Gandra
2024-11
Recruiting
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
NCT06663332Crohns Disease, Colitis, Ulcerative, Arthritis, Psoriatic, Arthritis, Juvenile
DrugGuselkumab
Janssen Research & Development, LLC
Phase 3
196
Braga, Porto
2024-10-29
Recruiting
Novartis Pharmaceuticals
Phase 1/2
232
Almada, Lisbon
2024-10-24
Recruiting
argenx
Phase 3
69
Braga, Vila Nova de Gaia
2024-10-18
Active, closed
Industrial Farmacéutica Cantabria, S.A.
Phase 3
520
Lisbon, Madeirã
2024-10-17
Active, closed
MoonLake Immunotherapeutics AG
Phase 3
960
Braga, Lisbon, Ponte de Lima
2024-10-15
Recruiting
Associação Centro de Apoio Tecnológico Agro Alimentar
Not applicable
33
Castelo Branco, Covilha
2024-10-11
Recruiting
Xencor, Inc.
Phase 1/2
270
Loures
2024-10-10
Active, closed
Novartis Pharmaceuticals
Phase 2
203
Vila Nova de Gaia
2024-10-09
By invitation
Academisch Ziekenhuis Maastricht
Not applicable
30
Portugal
2024-10-09
Recruiting
University of Lisbon
Not applicable
82
Lisbon
2024-10-08
Recruiting
Bristol-Myers Squibb
Phase 3
1,000
Lisbon, Coimbra, Porto
2024-10-07
Recruiting
Image-Based Prediction of Ventricular Tachycardia Events in Non-ischemic Cardiomyopathy
NCT06730464Dilated Cardiomyopathy, Arrhythmogenic Cardiomyopathy, Ventricular Arrhythmia, Hypertrophic Cardiomyopathies
Centro Medico Teknon
Observational
500
Lispon
2024-10-07
Active, closed
An At-distance and Online Intervention to Promote Parental Involvement and Self-regulation
NCT07400978Parental Involvement, Self-regulation in Children
University of Minho
Not applicable
150
Braga
2024-10-07
Recruiting
Exercise in Hereditary ATTR (ATTRv) Amyloidosis
NCT07033715Amyloidosis, Hereditary, Transthyretin-Related
University of Maia
Not applicable
42
Maia
2024-10-01
By invitation
Open-Label Extension Study to Assess GLM101 in PMM2-CDG Patients
NCT06657859Pmm2-CDG, Phosphomannomutase 2 Deficiency
Glycomine, Inc.
Phase 2
90
Porto
2024-09-30
Active, closed
Stemline Therapeutics, Inc.
Phase 3
4,556
Loures, Vila Franca de Xira, Porto, Vila Nova de Gaia, Coimbra, Faro, Lisbon, Setúbal
2024-09-27
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
406
Guimarães, Lisbon, Torres Vedras, Matosinhos Municipality
2024-09-26
Active, closed
Boehringer Ingelheim
Phase 3
1,666
Braga, Coimbra, Lisbon, Matosinhos Municipality, Vila Nova de Gaia
2024-09-26
Active, closed
Longboard Pharmaceuticals
Phase 3
108
Coimbra, Lisbon, Porto
2024-09-25
Active, closed
Genmab
Phase 3
699
Coimbra, Lisbon, Portimão, Porto, Vila Real
2024-09-25
Active, closed
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
NCT06481891Obstructive Cardiomyopathy, Hypertrophic, Non-obstructive Hypertrophic Cardiomyopathy
DrugSotagliflozin
Lexicon Pharmaceuticals
Phase 3
500
Braga, Faro, Lisbon, Porto
2024-09-24
Active, closed
Hoffmann-La Roche
Phase 3
338
Braga, Coimbra, Lisbon, Porto
2024-09-23
Recruiting
Janssen Research & Development, LLC
Phase 2/3
274
Coimbra, Porto
2024-09-19
Active, closed
argenx
Phase 3
141
Lisbon, Porto
2024-09-18
Active, closed
Zenas BioPharma (USA), LLC
Phase 2
190
Lisbon, Setúbal
2024-09-17
Active, closed
Hoffmann-La Roche
Phase 3
400
Braga, Lisbon, Portimão, Porto, Santa Maria da Feira, Viseu
2024-09-17
Recruiting
Egas Moniz - Cooperativa de Ensino Superior, CRL
Not applicable
60
Almada
2024-09-15
Active, closed
NEUROPSYCHOLOGICAL REHABILITATION FOR ALCOHOL USE DISORDERS
NCT06933186Alcohol Use Disorder Cognitive Decline
University of Lisbon
Not applicable
48
Lisbon
2024-09-15
Active, closed
Exercise Impact in Elderly With Multimorbidity: HbA1c and Blood Pressure
NCT06879639Hypertension, Diabetes, Osteoarthritis, Depression Disorders
Universidade do Porto
Not applicable
63
Vila Nova de Famalicão
2024-09-09
Recruiting
AbbVie
Phase 2
590
Guimarães, Lisbon, Braga, Coimbra, Viana do Castelo
2024-09-04
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Portuguese investigative site. Derived from ClinicalTrials.gov. Retrieved 12 November 2026. https://priyalifescience.com/clinical-trials-portugal

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Portugal and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 1,102 studies in total at the last sync on 11 Nov 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Portugal?

529 of the 1,102 studies in this register are recruiting new participants as of the 11 Nov 2026, 03:18 UTC sync. A further 99 have not yet opened recruitment, 425 are active but closed to new participants, and 49 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase, 1,102 studies
PhaseStudiesRecruitingShare
Phase 344818240.7%
Not applicable25611123.2%
Observational21212919.2%
Phase 287477.9%
Phase 2/333173%
Phase 1/224172.2%
Phase 421131.9%
Phase 119111.7%
Early Phase 1220.2%

Most active sponsors

Lead sponsors with the most studies
Lead sponsorStudiesRecruiting
Janssen Research & Development, LLC3915
Novartis Pharmaceuticals3613
Universidade do Porto359
AbbVie3313
AstraZeneca3311
Hoffmann-La Roche338
Merck Sharp & Dohme LLC3015
Amgen199
Boehringer Ingelheim1911
Novo Nordisk A/S195

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Browse trials by condition

Breast Cancer (26) Obesity (18) Heart Failure (17) Multiple Myeloma (14) Crohn's Disease (12) Non-small Cell Lung Cancer (10) Multiple Sclerosis (10) Systemic Lupus Erythematosus (10) Ovarian Cancer (9) Cancer (8) Ulcerative Colitis (8) Non-Small Cell Lung Cancer (7) Stroke (7) Carcinoma, Non-Small-Cell Lung (7) Relapsing Multiple Sclerosis (7)
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Browse trials by site location

Lisbon (691) Porto (539) Coimbra (254) Braga (184) Vila Nova de Gaia (109) Guimarães (89) Almada (85) Loures (68) Matosinhos Municipality (51) Aveiro (40) Carnaxide (36) Santa Maria da Feira (34) Amadora (27) Faro (24) Setúbal (23)
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.