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How the data is built

Methodology

Where every figure on our data registers comes from, how often it is refreshed, how records are matched to companies and medicines, and what the data cannot tell you.

01

The rules every register follows

Copied from the source, never estimated

Every record comes from an official register or a company's own regulatory filing. Figures are copied as published. Where we calculate something, such as a 12-month total, a share or a year-on-year change, the page says so. No figure is estimated, extrapolated or generated by AI.

Dated and sourced

Each register shows when it last synced with its source and lists its sources with their licences at the foot of the page. Most registers refresh nightly (from about 03:15 UTC); slower-moving data such as trade statistics and company filings refresh weekly.

A failed update keeps the last good data

If a source is unreachable or returns an error, the previous data stays up with its original sync date rather than an empty or partial register. The regulatory and company-financial updates also refuse a refresh that would suddenly shrink the data, treating it as a possible error until it is checked.

Scope stated on the page

Registers say what they include and leave out, for example which trial statuses or which approval route. Counts describe the register as stated, not a whole market.

02

Data families

sources, method and limits

Clinical trials

SourcesClinicalTrials.gov API v2 (US National Library of Medicine) for the country registers and the Irish dashboard; the EU Clinical Trials Information System (CTIS) for the EU register.
MethodA country register lists studies with at least one site in that country, selected on the registry's location-country field, not on free text. Each register states on the page which statuses and sponsors it includes. EU trials are shown with the CTIS status they carry; trials that were not authorised are left out.
LimitsRegistry records are entered by sponsors and can be late or incomplete. The same study can appear on ClinicalTrials.gov and CTIS under different identifiers, so the two are never added together.

Approvals, safety and patents

SourcesopenFDA (Drugs@FDA, device 510(k) clearances, enforcement reports), FDA Orange Book and Purple Book downloads, European Medicines Agency data files (medicines, orphan designations, safety communications), Health Canada Notice of Compliance data (Open Government Licence, Canada).
MethodRecords are copied field by field from the regulator's file. "First approved" dates are found by matching the active substance across regulators with a normalised substance name; biosimilars and generics are excluded from first-approval dates.
LimitsUS approvals from Drugs@FDA exclude most biologics regulated by CBER (vaccines, gene therapies). EU approvals cover the centralised procedure only, not national authorisations. Patent and exclusivity dates are the regulator's listed dates, not legal advice on when a product can be copied.

Medicine supply

SourcesThe FDA drug shortage database, EMA medicine shortage communications, the German BfArM supply-shortage register, and the HPRA list of medicines authorised in Ireland.
MethodEach shortage keeps the status and dates the regulator gives it. A company is linked to a shortage only when it is named on the regulator's record.
LimitsShortage lists change daily and are only as current as the last refresh shown on each page. A shortage can involve several manufacturers.

Irish economy and companies

SourcesCSO Ireland PxStat tables TSM09, TSM10 and MIM05 (CC BY 4.0); SEC EDGAR XBRL financial data from 10-K and 20-F annual reports; GLEIF legal entity data (CC0); CRO Open Data (CC BY 4.0).
MethodTrade values are the CSO's published figures; 12-month totals, shares and changes are calculated from them and labelled. Company financials are the values each group tagged in its annual report, in the currency it reports in, and each year comes from the latest report that includes it. Irish companies are linked to a group through GLEIF parent records or by name and registered address, checked by hand.
LimitsThe CSO revises recent months and suppresses some series for confidentiality. Groups that do not file with the SEC have no financial figures here. Register records are linked to company pages by the organisation names they carry, which can miss or mismatch a name; each company page lists the names it matched.
03

Corrections and questions

When we get it wrong

Errors are fixed and recorded in the public corrections log, with what was wrong and what changed. Our wider policy is in the editorial standards.

Report an error or reuse the data

Email info@priyalifescience.com or use the contact form, naming the page and the figure. Most registers can be downloaded as CSV from their own page; please credit the original source and Priya Life Science.