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Clinical Trials in Portugal / NCT07597291
Recruiting Observational

Cardiovascular Outcomes Registry in Cardiogenic SHOCK (COR-SHOCK)

NCT07597291 · tracked via the Priya Life Science Portugal tracker
Sponsor
Hospital de Santa Cruz, Portugal
Phase
Observational
Started
2026-06-10
Last updated
2026-06-11

Condition(s) studied

Cardiogenic Shock AcuteCardiogenic ShockCardiogenic Shock Post Myocardial Infarction

Study summary

The goal of this observational study is to evaluate the clinical outcomes and management approaches of cardiogenic shock throughout the years in adult patients admitted to a Cardiology Department. The main questions it aims to answer are:

* How have management strategies and clinical outcomes for cardiogenic shock evolved over time?
* How do clinical, laboratory, and advanced hemodynamic monitoring parameters relate to patient survival and overall prognosis in this population?

Researchers will evaluate clinical data collected from 2017 onwards to see if therapeutic advancements and changes in clinical management over the years have led to improved patient survival and quality of care.

Participants will:

* Receive standard, routine medical care for cardiogenic shock as determined by their clinical team (no experimental interventions will be introduced).
* Have their clinical, laboratory, and imaging data collected from hospital electronic records during their stay.
* Be followed for up to 1 year after hospital admission to evaluate long-term survival and clinical outcomes.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: -Cardiogenic shock according to the following criteria: Cardiac disorder resulting in hypotension, defined as at least one of the following: * Systolic blood pressure (SBP) \<90 mmHg for ≥30 minutes, or * Requirement for vasopressors, inotropes, or mechanical circulatory support to maintain SBP ≥90 mmHg AND Evidence of tissue hypoperfusion, defined by the presence of at least one of the following: * Serum lactate \>2 mmol/L * Acute kidney injury and/or oliguria * Acute hepatic injury * Cool or mottled extremities * Altered mental status AND Clinical presentation judged to be primarily attributable to a cardiac etiology. Exclusion Criteria: * Age \< 18 years. * Other primary etiologies of shock at presentation (e.g., hypovolemic, hemorrhagic, septic, obstructive shock due to acute pulmonary embolism, or anaphylactic shock). * Refusal to participate in the study (applicable only to the prospective cohort).

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Unidade Local de Saúde de Lisboa Ocidental Carnaxide Lisbon District Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07597291 on ClinicalTrials.gov ↗ ← All trials in Portugal