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Compound · clinical trials

Telisotuzumab Adizutecan

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 13 trials in our USA, China and UK registers that name Telisotuzumab Adizutecan as an intervention. Synced 24 Sep 2026
13Trials tracked
10Recruiting now
1Lead sponsor
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Telisotuzumab Adizutecan is named as a drug or biological intervention in 13 clinical trials in our USA, China and UK trial registers, 10 of which are recruiting. The lead sponsor is AbbVie. Registered phases: Phase 2, Phase 2/3, Phase 1, Phase 1/2 and Phase 3. Conditions studied include Colorectal Cancer; Non-Small Cell Lung Cancer; Metastatic Colorectal Cancer.

01

Clinical trials of Telisotuzumab Adizutecan

13 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT07525206 A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer (ClinicalTrials.gov ↗)
Colorectal Cancer
Phase 3 Recruiting AbbVie USA, China
NCT07005102 A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-Squamous Non-Small Cell Lung Cancer
Phase 2/3 Recruiting AbbVie USA, China
NCT07155187 A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-Small Cell Lung Cancer
Phase 2/3 Recruiting AbbVie UK, USA, China
NCT07490301 A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma (ClinicalTrials.gov ↗)
Metastatic Pancreatic Ductal Adenocarcinoma, PDAC
Phase 2/3 Recruiting AbbVie UK, USA, China
NCT06820463 A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer (ClinicalTrials.gov ↗)
Metastatic Colorectal Cancer
Phase 2 Recruiting AbbVie UK, USA
NCT07023289 A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease (ClinicalTrials.gov ↗)
Colorectal Cancer
Phase 2 Recruiting AbbVie USA, China
NCT07196644 A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan (ClinicalTrials.gov ↗)
Solid Tumors Harboring MET Amplification
Phase 2 Recruiting AbbVie USA
NCT07769502 A Study to Assess Adverse Events and Change in Disease Activity With Treatment Combinations With Telisotuzumab Adizutecan in Adults Participants With Pancreatobiliary Cancers (ClinicalTrials.gov ↗)
Pancreatobiliary Cancers, Pancreatic Ductal Adenocarcinoma
Phase 2 Recruiting AbbVie China
NCT06772623 Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations (ClinicalTrials.gov ↗)
Non Small Cell Lung Carcinoma
Phase 1/2 Recruiting AbbVie UK, USA, China
NCT05005403 Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Micro Satellite Stable Colorectal Cancer
Phase 1 Recruiting AbbVie USA
NCT06614192 A Study Assessing Adverse Events and Disease Activity of Intravenously (IV) Infused Telisotuzumab Adizutecan in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer (ClinicalTrials.gov ↗)
Metastatic Colorectal Cancer
Phase 2 Active, closed AbbVie USA, China
NCT06628310 A Study to Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ClinicalTrials.gov ↗)
Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Esophageal Adenocarcinoma
Phase 2 Active, closed AbbVie UK, USA, China
NCT06464692 Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Adizutecan (ABBV-400) Moves Through the Body of Adult Participants With Unresectable Locally Advanced/Metastatic Colorectal Cancer (ClinicalTrials.gov ↗)
Colorectal Cancer
Phase 1 Active, closed AbbVie China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

16 conditions
Condition (as registered)Trials
Colorectal Cancer3
Non-Small Cell Lung Cancer2
Metastatic Colorectal Cancer2
Non Small Cell Lung Carcinoma1
Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma1
Gastroesophageal Junction Adenocarcinoma1
Esophageal Adenocarcinoma1
Metastatic Pancreatic Ductal Adenocarcinoma1
PDAC1
Head and Neck Squamous Cell Carcinoma1
Micro Satellite Stable Colorectal Cancer1
Gastric/Esophageal Cancer1
Solid Tumors Harboring MET Amplification1
Non-Squamous Non-Small Cell Lung Cancer1
Pancreatobiliary Cancers1
Pancreatic Ductal Adenocarcinoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
AbbVie13
04

Trials by country register

RegisterTelisotuzumab Adizutecan trials
Clinical trials in USA11
Clinical trials in China10
Clinical trials in UK5

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Telisotuzumab Adizutecan works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Telisotuzumab Adizutecan (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.