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Compound · clinical trials

Xaluritamig

Also listed in trial records as AMG 509
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 8 trials in our USA, UK and China registers that name Xaluritamig as an intervention. Synced 24 Sep 2026
8Trials tracked
6Recruiting now
1Lead sponsor
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Xaluritamig is named as a drug or biological intervention in 8 clinical trials in our USA, UK and China trial registers, 6 of which are recruiting. The lead sponsor is Amgen. Registered phases: Phase 1 and Phase 3. Conditions studied include Prostate Cancer; Metastatic Castration-resistant Prostate Cancer; Metastatic Hormone-sensitive Prostate Cancer (mHSPC).

01

Clinical trials of Xaluritamig

8 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT07213674 A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naรฏve Metastatic Castration-resistant Prostate Cancer
Metastatic Castration-resistant Prostate Cancer
Phase 3 Recruiting Amgen UK, USA
NCT04221542 Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer (ClinicalTrials.gov ↗)
Prostate Cancer
Phase 1 Recruiting Amgen USA, China
NCT06613100 Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer
Prostate Cancer
Phase 1 Recruiting Amgen USA
NCT07140900 Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer (ClinicalTrials.gov ↗)
Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Phase 1 Recruiting Amgen USA
NCT07297979 Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS) (ClinicalTrials.gov ↗)
Ewing Sarcoma
Phase 1 Recruiting Amgen USA
NCT07493512 Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer (ClinicalTrials.gov ↗)
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Phase 1 Recruiting Amgen USA
NCT06691984 Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute) (ClinicalTrials.gov ↗)
Metastatic Castration-resistant Prostate Cancer
Phase 3 Active, closed Amgen UK, USA
NCT06555796 Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Cancer (ClinicalTrials.gov ↗)
Prostate Cancer, High-risk Biochemical Recurrence, High Risk Biochemical Recurrence of Non-metastatic Castration-sensitive Prostate Cancer
Phase 1 Active, closed Amgen USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

8 conditions
Condition (as registered)Trials
Prostate Cancer3
Metastatic Castration-resistant Prostate Cancer2
Metastatic Hormone-sensitive Prostate Cancer (mHSPC)1
Metastatic Castration-resistant Prostate Cancer (mCRPC)1
High-risk Biochemical Recurrence1
High Risk Biochemical Recurrence of Non-metastatic Castration-sensitive Prostate Cancer1
Non-metastatic Castration-sensitive Prostate Cancer1
Ewing Sarcoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Amgen8
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Xaluritamig works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Xaluritamig (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.