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Compound · clinical trials

Efti clinical trials

Also listed in trial records as Eftilagimod alfa, IMP321, LAG-3Ig, LAG-3Ig fusion protein, Pembrolizumab, Eftilagimod alfa
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 3 trials in our Germany, Poland, Ireland, UK, USA, India, Spain, Italy, Belgium, Austria, Portugal, Turkey, Canada, Brazil, Mexico and Australia registers that name Efti as an intervention. Synced 26 Sep 2026
3Current trials
0Recruiting now
3Lead sponsors
16Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Efti is named as an intervention in 3 current clinical trials in our Germany, Poland, Ireland, UK, USA, India, Spain, Italy, Belgium, Austria, Portugal, Turkey, Canada, Brazil, Mexico and Australia registers. None are recruiting at the moment. The most common phase is Phase 3. The sponsor with the most trials is Immutep S.A.S (1). The most-studied condition is Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC).

Trials by status

  • Active, closed3100%

Trials by phase

  • Phase 3133%
  • Phase 1133%
  • Phase 2133%
01

Clinical trials of Efti

3 trials
StudyPhaseStatusLead sponsorRegisters
Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)
NCT06726265 · ClinicalTrials.gov ↗ · Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Phase 3 Active, closed Immutep S.A.S Ireland, UK, USA, India, Germany, Spain, Italy, Belgium, Poland, Austria, Portugal, Turkey, Canada, Brazil, Mexico, Australia
Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial
NCT06128863 · ClinicalTrials.gov ↗ · Neoadjuvant, Immunotherapy, Sarcoma,Soft Tissue
Phase 2 Active, closed Maria Sklodowska-Curie National Research Institute of Oncology Poland
Feasibility and Safety of IMP321 (Eftilagimod Alpha) for Advanced Stage Solid Tumors
NCT03252938 · ClinicalTrials.gov ↗ · Solid Tumors, Peritoneal Carcinomatosis, NSCLC Adenocarcinoma
Phase 1 Active, closed Institut fรผr Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Germany

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Efti

9 conditions
Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)1Solid Tumors1Peritoneal Carcinomatosis1NSCLC Adenocarcinoma1Urothelial Carcinoma1Neoadjuvant1Immunotherapy1Sarcoma,Soft Tissue1Radiation Therapy1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Immutep S.A.S1
Institut fรผr Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest1
Maria Sklodowska-Curie National Research Institute of Oncology1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Germany20
Clinical trials in Poland20
Clinical trials in Ireland10
Clinical trials in UK10
Clinical trials in USA10
Clinical trials in India10
Clinical trials in Spain10
Clinical trials in Italy10
Clinical trials in Belgium10
Clinical trials in Austria10
Clinical trials in Portugal10
Clinical trials in Turkey10
Clinical trials in Canada10
Clinical trials in Brazil10
Clinical trials in Mexico10
Clinical trials in Australia10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Efti trials

How many clinical trials are testing Efti?

3 current trials in our Germany, Poland, Ireland, UK, USA, India, Spain, Italy, Belgium, Austria, Portugal, Turkey, Canada, Brazil, Mexico and Australia registers name Efti (also registered as IMP321) as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Efti trials recruiting patients?

Not at the moment. None of the 3 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.

Who sponsors Efti clinical trials?

Immutep S.A.S (1), Institut fรผr Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest (1) and Maria Sklodowska-Curie National Research Institute of Oncology (1). The number in brackets is how many trials each organisation leads.

Are there Efti clinical trials in Ireland?

Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Efti works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Efti works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Efti (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.