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Trackers› Clinical trials› Germany
Clinical trial register · Germany

Studies with a German investigative site

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5051 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:51 UTC
5051
Studies in scope
all four open statuses
2882
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1584 Hamburg 889 Essen 760 Dresden 707 Heidelberg 627
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Recruitment status
Phase
Lead sponsor
AstraZeneca185 Novartis Pharmaceuticals142 Hoffmann-La Roche101 Charite University, Berlin, Germany99 Merck Sharp & Dohme LLC97
Site location
Berlin1584 Hamburg889 Essen760 Dresden707 Heidelberg627
All 635 locations
Target enrolment
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Trials in this register

5051 of 5051 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Not yet open
Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)
NCT07586150Severe Mental Illness, Depression / Major Depressive Disorder, Bipolar Disorder (BD), Schizophrenia
DrugSemaglutide
Ludwig-Maximilians - University of Munich
Not applicable
140
Mannheim, München
2028-10
Not yet open
Genetic Ablation of CD33 in HSC to Broaden the Therapeutic Index of CD33-directed Immunotherapy in Patients with AML
NCT05662904Relapsed/Refractory Acute Myeloid Leukemia (AML)
DrugGemtuzumab Ozogamicin
German Cancer Research Center
Phase 1
12
Dresden, Heidelberg
2028-01
Not yet open
Simulation-Based Patient Education to Address Radiotherapy-Related Anxiety in Cancer Patients (ARAISE)
NCT07721246Neoplasms, Anxiety
University Medical Center Goettingen
Not applicable
144
Göttingen
2028-01
Not yet open
An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of ALXN2220 in Adults With Transthyretin Amyloid Cardiomyopathy
NCT07789483Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
DrugALXN2220
Alexion Pharmaceuticals, Inc.
Phase 3
1,180
Berlin, Hanover, Münster, Cologne, Homburg, Leipzig, Kiel, Essen
2027-11-23
Not yet open
Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy
NCT02199015Cerebral Palsy, Spasticity
Juan Carlos M. Andreani MD
Not applicable
40
Magdeburg
2027-06-01
Not yet open
Liver Transplantation for Non-Resectable Colorectal Liver Metastases Without Local Treatment Options
NCT07811453Colorectal Neoplasms, Liver Neoplasms, Neoplasm Metastases, Colorectal Liver Metastases
Charite University, Berlin, Germany
Not applicable
260
Berlin
2027-04-01
Not yet open
Study Comparing Two Administration Pathways for Adenosine During Microvascular Function Assessment
NCT06269874Microvascular Coronary Artery Disease
Johannes Gutenberg University Mainz
Not applicable
40
Mainz
2027-03-02
Not yet open
Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) Trial
NCT07683923SCAD, ACS (Acute Coronary Syndrome)
DrugsAcetylsalicylic acid ASA·Clopidogrel
Universitätsklinikum Hamburg-Eppendorf
Phase 4
3,518
Hamburg
2027-03-01
Not yet open
A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis
NCT07335562Systemic Sclerosis
DrugsZola-cel·Nintedanib·Tocilizumab·Fludarabine
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 3
92
Berlin, Cologne, Erlangen, Leipzig, München, Tübingen, Würzburg
2027-02-03
Recruiting
AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure
NCT06650995HFpEF - Heart Failure With Preserved Ejection Fraction, Atrial Fibrillation
Technical University of Munich
Not applicable
40
Munich
2027-02-01
Not yet open
A Comparison of Left Bundle Branch Optimized Cardiac Resynchronization Therapy vs Left Bundle Branch Area Pacing Alone
NCT07842874Heart Failure, Left Bundle Branch Area Pacing, Cardiac Resynchronization Therapy, Conduction System Pacing
PD Dr. Guram Imnadze
Not applicable
124
Neuruppin
2027-02
Not yet open
Asciminib Frontline Risk Adapted
NCT07804901Chronic Myeloid Leukemia (CML)
DrugDasatinib
Prof. Dr. med. Andreas Hochhaus
Phase 2
200
Jena
2027-01-01
Not yet open
A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With Schizophrenia
NCT07084831Schizophrenia; Psychosis, Cognitive Impairment
European Group for Research In Schizophrenia
Phase 3
171
Augsburg, Cologne, Mannheim, München
2027-01-01
Not yet open
Evaluating Practices That Foster Care Partnerships and Wellbeing Among Informal Carers and Long-term Care Workers
NCT07708649Mental Wellbeing
VU University of Amsterdam
Not applicable
450
Zittau
2027-01-01
Not yet open
A Study to Learn About How Safe Nitroglycerin is and How it Affects the Body When Taken Along With Nurandociguat in People With Coronary Artery Disease
NCT07431294Stable Coronary Artery Disease
DrugNitroglycerin
Bayer
Phase 1
36
Heidelberg, Bonn, Erfurt, Berlin
2027-01-01
Not yet open
Minimally-invasive ICG-guided Retroperitoneal Sentinel Lymph Node Dissection in the Primary Staging of Testicular Cancer Versus Standard of Care
NCT07699640Testicular Cancer, Testicular Germ Cell Tumor
Heinrich-Heine University, Duesseldorf
Not applicable
171
Ulm, Würzburg, Hamburg, Marburg, Cologne, Düsseldorf, Wuppertal, Dresden
2027-01
Not yet open
Weekly Online CT or MR Adaptive Definitive SBRT for Regionally Metastatic Prostate Cancer
NCT07591051Prostate Cancer
University of Zurich
Not applicable
54
Heidelberg
2027-01
Not yet open
An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health
NCT05477953Chagas Disease
Bayer
Observational
50
Multiple Locations
2026-12-31
Not yet open
Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in Participants With Pulmonary Fibrosis
NCT07441408Pulmonary Fibrosis
DrugAdmilparant
Bristol-Myers Squibb
Phase 3
2,380
Stralsund, Coswig
2026-12-16
Not yet open
CD19-B Cell Depletion in PAIS-ME/CFS Patients
NCT07724834Post-acute Infectious Syndrome (PAIS), Post-COVID 19 Condition (PCC or Long COVID), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
DrugInebilizumab
Charite University, Berlin, Germany
Phase 2
38
Berlin
2026-12-01
Not yet open
Etenta-Isa-VRd in Newly Diagnosed High-Risk Multiple Myeloma
NCT07600151Myeloma Multiple, Myeloma
DrugsEtentamig·Isatuximab·Bortezomib·Lenalidomide
Universitätsklinikum Hamburg-Eppendorf
Phase 1/2
220
Hamburg
2026-12-01
Not yet open
Dalbavancin Therapy for Infective Endocarditis
NCT07699211Endocarditis Infective, Endocarditis, Bacterial
DrugDalbavancin administration
Stefan Hagel
Phase 3
184
Freiburg im Breisgau, Regensburg, Hamburg, Cologne, Leipzig, Berlin, Erfurt, Jena
2026-12
Not yet open
DEXA Bone Density Analysis of the CoreHip® Prosthesis System
NCT06632301Primary Osteoarthritis, Cartilage Degeneration, Osteoarthritis, Hip, Inflammatory Arthritis
Aesculap AG
Not applicable
40
Hanover
2026-12
Not yet open
A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma
NCT07728188Relapsed or Refractory Multiple Myeloma
DrugsEtentamig·Teclistamab·Carfilzomib·Pomalidomide
AbbVie
Phase 3
520
Freiburg im Breisgau, Karlsruhe, Tübingen, Ulm, Würzburg, Hanover, Bonn, Cologne
2026-11-30
Not yet open
Study of PM54 in Combination With Cytotoxic and Targeted Agents in Adult Participants With Advanced Malignancies
NCT07839819Advanced Solid Tumor
DrugsPM54·Doxorubicin·Irinotecan
PharmaMar
Phase 1/2
231
Buckow, Mainz
2026-11-12
Not yet open
A Study to Understand How Nerandomilast Works in People With Active Idiopathic Inflammatory Myopathies
NCT07789015Idiopathic Inflammatory Myopathies
DrugNerandomilast
Boehringer Ingelheim
Phase 3
270
Bad Bramstedt, Berlin, Cologne, Erlangen, Freiburg im Breisgau, Halle, Jena, Kirchheim unter Teck
2026-11-09
Not yet open
Intraoperative Application of Cold Atmospheric Plasma to Prevent Postoperative Wound Complications in the Inguinal Region of High-risk Patients With Peripheral Arterial Occlusive Disease
NCT07571408Peripheral Occlusive Disease, Wound Healing, Wound Healing Complication, Cold Atmospheric Plasma
Ursula Werra
Not applicable
214
Cologne
2026-11-01
Not yet open
Analysis of Continuous Kidney Replacement Therapy (CKRT) Treatments With multiFlux Hemofilters Using Regional Citrate Anticoagulation (RCA) or Systemic Heparin Anticoagulation
NCT07679568Acute Kidney Injury, Renal Failure
Fresenius Medical Care Deutschland GmbH
Observational
62
Munich
2026-11
Not yet open
Phase II Study of Upfront SRT Plus Ivonescimab/Chemotherapy vs Ivonescimab/Chemotherapy in NSCLC Brain Mets
NCT07234877Non Small Cell Lung Cancer
DrugsPaclitaxel-albumin·Ivonescimab·Pemetrexed·Paclitaxel
European Organisation for Research and Treatment of Cancer - EORTC
Phase 2
158
Frankfurt am Main, Jena, Rostock
2026-11
Not yet open
Safety and Efficacy of Ruxolitinib in Patients With HNSCC and High NLR Treated With Pembrolizumab - The Phase 2 InflammaSTOP Trial
NCT07840456Carcinoma, Squamous Cell of Head and Neck HNSCC
DrugsRuxolitinib·Pembrolizumab
University Hospital, Basel, Switzerland
Phase 2
66
Würzburg, Greifswald, Cologne, Hagen, Hamburg
2026-11
Not yet open
Addition of Platinum-based Chemotherapy to Tislelizumab in PD-L1high Metastatic Non-small Cell Lung Cancer With a High Tumor Burden
NCT07715396Non-small Cell Lung Cancer Metastatic
DrugsTislelizumab·Pembrolizumab
AIO-Studien-gGmbH
Phase 3
230
Frankfurt
2026-10-30
Not yet open
Balloon- Versus Self-Expanding Intraannular TAVI in Small Aortic Annuli
NCT07794306Aortic Valve Stenosis
Universitätsklinikum Hamburg-Eppendorf
Not applicable
510
Hamburg
2026-10-26
Not yet open
Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor
NCT07557147Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Bayer
Observational
60
Heidelberg
2026-10-15
Not yet open
A Long-Term Extension (LTE) Study Of Enpatoran In Cutaneous Manifestations Of Lupus With Or Without Systemic Disease [Elowen-LTE]
NCT07840287Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE)
DrugEnpatoran
EMD Serono Research & Development Institute, Inc.
Phase 3
404
Darmstadt
2026-10-15
Not yet open
Evaluation of the Safety and Effectiveness of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in Adults Living With Type 1 Diabetes
NCT07401901Type 1 Diabetes (T1D)
Medtronic MiniMed, Inc.
Not applicable
230
Bad Oeynhausen, Hamburg, Rostock
2026-10-15
Not yet open
A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A
NCT07830732Haemophilia A
Novo Nordisk A/S
Phase 3
84
Berlin, Bonn, Hanover, Leipzig, Regensburg
2026-10-09
Not yet open
Post-acute Infectious Syndrome - Aripiprazole Symptom Evaluation (PAIS-AriSE)
NCT07714213Post-acute Infectious Syndrome (PAIS), Post-COVID-19 Condition (PCC or Long COVID)
DrugAripiprazole
Christiana Franke
Phase 2
138
Berlin
2026-10-01
By invitation
International Multicenter Outcomes of Transcatheter Pulmonary Flow Restrictors in Congenital and Acquired Heart Disease
NCT07791069Congenital Heart Disease
Fondation Hôpital Saint-Joseph
Observational
150
Hamburg
2026-10-01
Not yet open
OM336 in Sensitized Transplant Candidates
NCT07789431Highly Sensitized Patients Awaiting Kidney Transplant
Medical University of Vienna
Phase 2
12
Berlin
2026-10-01
Not yet open
Surgical Treatment of Adjacent Segment Stenosis
NCT07661199Adjacent Segment Disease, Lumbar Spinal Stenosis
Charite University, Berlin, Germany
Not applicable
338
Berlin
2026-10-01
Not yet open
Impact of Iron Supplementation During Pregnancy
NCT07814378Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
DrugIron
Johann Wolfgang Goethe University Hospital
Observational
800
Frankfurt, Würzburg
2026-10-01
Recruiting
Reduction of SystemiC Inflammation After Ischemic Stroke by Intravenous DNase Administration (ReSCInD)
NCT05880524Ischemic Stroke, Inflammatory Response
DrugDornase Alfa
Ludwig-Maximilians - University of Munich
Phase 2
36
Munich, Berlin, Hamburg, Hanover
2026-10-01
Not yet open
Continuous or Intermittent Cetuximab Plus FOLFIRI as First-line Treatment in RAS/BRAF Wild-type mCRC Patients
NCT07004413Colorectal Cancer Metastatic
DrugsFolfiri·Cetuximab
Charite University, Berlin, Germany
Phase 3
267
Berlin
2026-10-01
Not yet open
Routine Microaxial Heart Pump Support and Protocolized Pulmonary Artery Catheter Monitoring Versus Standard Care in Heart Attack-Related Cardiogenic Shock
NCT07762560Cardiogenic Shock, Acute Myocardial Infarction (AMI), Heart Failure, Acute
Leipzig Heart Science gGmbH
Not applicable
780
Leipzig
2026-10-01
Not yet open
AngioVac Aspiration Therapy Registry
NCT07769320Intracardiac Thrombus, Intracardiac Mass, Intravascular Thrombosis, Vegetation; Heart
Charite University, Berlin, Germany
Observational
1,000
Berlin
2026-10-01
Not yet open
Microbiology Operations & Time Optimization in Sepsis
NCT07817043Sepsis, Bloodstream Infection, Bacterial Infections, Septic Shock
University Medicine Greifswald
Observational
1,000
Greifswald
2026-10-01
Not yet open
Remote Monitoring and Optimization of Heart Failure Therapy
NCT07622472Heart Failure
Zoll Medical Corporation
Not applicable
800
Giessen
2026-10-01
Recruiting
Cevostamab in Combination With Pomalidomide and Dexamethasone After BCMA- Targeting CAR T-Cell Therapy in Participants With Previously Treated Multiple Myeloma
NCT07825064Multiple Myeloma
DrugsCevostamab·Pomalidomide·Tocilizumab·Dexamethasone
Hoffmann-La Roche
Phase 2
45
Jena
2026-10-01
Not yet open
ESR1Real World Assessment Prevalence Study
NCT07817212HR+/HER2- aBC Undergoing 1L Treatment With CDK4/6i (Palbociclib, Abemaciclib or Ribociclib) and AI (Anastrozole or Letrozole)
Institut fuer Frauengesundheit
Not applicable
1,550
Ansbach, Bremen, Celle, Dresden, Düsseldorf, Erlangen, Homburg, Ilsede
2026-10-01
Not yet open
Study to Evaluate the Effect of a Single Oral Dose of Zoliflodacin 3 g on Testicular Function in Healthy Adult Men
NCT07640477Testicular Abnominalies
Global Antibiotics Research and Development Partnership
Phase 4
200
Berlin
2026-10
Not yet open
A Study to Assess the Safety, Pharmacokinetics, and Efficacy of ABI-6250 in Participants With Chronic Hepatitis D Virus Infection
NCT07762027Chronic Hepatitis D Infection
Assembly Biosciences
Phase 2
80
Hamburg, Hanover
2026-10
Not yet open
PULSTA TPV Observational Study
NCT07747207Heart Disease
Taewoong Medical Co., Ltd.
Observational
200
Munich
2026-10
Not yet open
IMPLEMENTING PATIENTS' COMPETENCE IN ORAL EBC THERAPY PERSISTENCE
NCT07521202HR+/HER2- Early Breast Cancer
Institut fuer Frauengesundheit
Not applicable
257
Erlangen
2026-10
Not yet open
A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events
NCT07474649Coronary Atherosclerosis, Mixed Dyslipidemia, Hypercholesterolemia
DrugsBempedoic acid·Ezetimibe·Rosuvastatin·Atorvastatin
Daiichi Sankyo
Phase 3
103
Berlin, Hamburg, Mainz, Mannheim
2026-09-30
Not yet open
Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02)
NCT07680790Non-Small Cell Lung Cancer
DrugsIza-bren·Osimertinib·Pemetrexed·Cisplatin
Bristol-Myers Squibb
Phase 3
850
Gerlingen, Ulm, Wangen, Munich, Regensburg, Frankfurt am Main, Oldenburg, Cologne
2026-09-30
Not yet open
External Beam Radiotherapy Combined With Endorectal High-dose-rate Brachytherapy in Elderly and Frail Patients With Rectal Cancer
NCT06729645Rectal Cancer
University Hospital of Cologne
Not applicable
80
Kempten, Frankfurt am Main, Cologne, Leipzig
2026-09-30
Not yet open
DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers
NCT07707895Small Cell Lung Cancer, Large Cell Neuroendocrine Lung Carcinoma, Extrapulmonary Neuroendocrine Carcinoma of Small Cell Histology, Extrapulmonary Neuroendocrine Carcinoma of Large Cell Histology
DrugsZL-1310·Obrixtamig·Atezolizumab
Boehringer Ingelheim
Phase 1/2
60
Mainz, Stuttgart
2026-09-29
Not yet open
Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian Cancer
NCT07816666Platinum-sensitive Relapsed Epithelial Ovarian Cancer, Platinum-sensitive Relapsed Fallopian Tube Cancer, Platinum-sensitive Relapsed Primary Peritoneal Cancer
DrugsTorvutatug samrotecan·Bevacizumab
AstraZeneca
Phase 3
600
Bad Homburg, Bonn, Brandenburg, Gütersloh, Homburg, Kassel, Mainz, Mannheim
2026-09-29
Not yet open
Pix-Risk: Early Detection of Rheumatoid Arthritis Via the DETECTRA Platform
NCT07825233Rheumatoid Arthritis (RA
Centre Hospitalier Universitaire Vaudois
Not applicable
142
Berlin, Bochum
2026-09-28
Not yet open
A Study to Assess the Effects of Probenecid on the Pharmacokinetics of Mirdametinib and Its Metabolites in Healthy Participants
NCT07840612Healthy
DrugsProbenecid·Mirdametinib
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Phase 1
17
Darmstadt
2026-09-25
Not yet open
Evaluation of Solanidine as an Exogenous Biomarker to Phenotype CYP2D6 Activity in Humans
NCT07817030Pharmacokinetic Study in Healthy Volunteers
University Medicine Greifswald
Not applicable
30
Greifswald
2026-09-21
Recruiting
A Study to Test How Well Different Doses of BI 3822971 Are Tolerated by People With Advanced Cancer (Solid Tumours)
NCT07744152Solid Tumours
Boehringer Ingelheim
Phase 1
137
Dresden, München
2026-09-21
Recruiting
A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis
NCT07412704Arthritis, Rheumatoid
Bristol-Myers Squibb
Phase 1/2
84
München, Berlin, Cologne, Herne, Sendenhorst
2026-09-15
Recruiting
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
NCT07648264Secondary Immune Deficiency
DrugHizentra
CSL Behring
Phase 3
63
Giessen, Mainz
2026-09-15
Not yet open
Health Behaviour and Readiness to Change After Myocardial Infarction: A Cross-sectional Survey
NCT07785921Cardiovascular (CV) Risk, Heart Attack Patients
Kliniken Essen-Mitte
Observational
143
Essen
2026-09-15
Recruiting
Efficacy and Safety of SP16 in Preventing Acute Kidney Injury in At-risk Subjects With Chronic Kidney Disease Undergoing Elective Cardiac Surgery Using the Heart-lung-machine
NCT07661940AKI - Acute Kidney Injury
University of Erlangen-Nürnberg Medical School
Phase 2
120
Erlangen
2026-09-14
Recruiting
FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression
NCT07540988Interstitial Lung Diseases
DrugNerandomilast
Boehringer Ingelheim
Phase 3
466
Berlin, Bonn, Essen, Hanover, Heidelberg, Immenhausen, München, Stuttgart
2026-09-14
Not yet open
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
NCT07285798Irritability Associated With Autism Spectrum Disorder
DrugsKarX-EC·KarXT
Bristol-Myers Squibb
Phase 3
176
Gdansk
2026-09-11
Recruiting
A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum
NCT07811193Colorectal Adenocarcinoma
DrugsVVD-133214·Pembrolizumab
Vividion Therapeutics, Inc.
Phase 2
140
Ulm, Schweinfurt, Hamburg, Frankfurt am Main, Oldenburg, Essen, Berlin
2026-09-11
Recruiting
A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Verducatib in the Blood
NCT07781631Healthy
DrugsVerducatib·Carbamazepine
Boehringer Ingelheim
Phase 1
20
Berlin
2026-09-10
Recruiting
A Phase I/II Trial of JR-446 in Mucopolysaccharidosis Type IIIB (MPS IIIB)
NCT07640984Mucopolysaccharidosis IIIB
DrugJR-446
JCR Pharmaceuticals Co., Ltd.
Phase 1/2
12
Hamburg
2026-09-09
Recruiting
A Study in Healthy People to Test How Zongertinib is Taken up in the Body When Given as Tablets Made by Two Different Manufacturers With or Without Food
NCT07789028Healthy
DrugZongertinib
Boehringer Ingelheim
Phase 1
56
Biberach
2026-09-09
Recruiting
A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia
NCT07623200Essential Thrombocythemia
DrugINCA033989
Incyte Corporation
Phase 3
426
Aachen, Berlin, Dresden, Freiburg im Breisgau, Halle, Hamburg, Hanover, Homburg
2026-09-08
Not yet open
A Research Study Looking at the Effect of Timing of Meal After Dosing and Water Volume at Dosing on How the Medicine Zenagamtide is Taken up by the Body of Participants With Overweight or Obesity
NCT07815067Overweight, Obesity
DrugZenagamtide
Novo Nordisk A/S
Phase 1
320
Berlin
2026-09-07
Recruiting
Resistance Training to Prevent Muscle Loss During Treatment With Tirzepatide
NCT07777575Obesity (BMI>30)
Technical University of Munich
Phase 4
150
München
2026-09-07
Not yet open
A Research Study Looking Into How a Single Dose of the Medicine NNC0537-1482 Moves Through the Body of Participants With Normal or Reduced Kidney Function
NCT07808788Chronic Kidney Disease
DrugNNC0537-1482
Novo Nordisk A/S
Phase 1
54
Berlin
2026-09-04
Not yet open
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
NCT07772180Psychiatric Disorder
Max-Planck-Institute of Psychiatry
Not applicable
30
Munich
2026-09-03
By invitation
Online Socio-emotional Dyad Training for Healthcare Professionals' Well-being and Social Skills, Phase II.
NCT07637422Intervention Condition, Control Condition
Max Planck Social Neuroscience Lab
Not applicable
666
Berlin
2026-09-02
Recruiting
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
NCT07623161Myelofibrosis, Anemia
DrugElritercept
Takeda
Phase 3
324
Freiburg im Breisgau, Heidelberg, Mutlangen, Minden, Koblenz, Chemnitz, Halle, Jena
2026-09-02
Recruiting
A Study to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body When Given by Injection in Healthy Men and Women With and Without Overweight or Obesity
NCT07768813Healthy, Obesity
DrugSurvodutide
Boehringer Ingelheim
Phase 1
44
Mannheim
2026-09-02
Recruiting
Hyperspectral Imaging in Robot-Assisted Partial Nephrectomy
NCT07803315Kidney Neoplasm, Renal Mass up to 7cm
University of Leipzig
Observational
60
Leipzig
2026-09-01
Not yet open
REtrieval of Transurethrally Resected Intact En-bloc Vesical Tumors Using a Retrieval Device for Bladder Tumors
NCT07762820Bladder Cancer, Bladder Cancer TNM Staging Primary Tumor (T) T1
Ludwig-Maximilians - University of Munich
Not applicable
75
Augsburg, Erlangen, Munich, Nuremberg
2026-09-01
Not yet open
DKK3 as a Biomarker of Peritoneal Fibrosis in Peritoneal Dialysis Patients
NCT07806708Peritoneal Dialysis (PD), End Stage Renal Disease (ESRD), Peritoneal Fibrosis, Ultrafiltration Failure
Universität des Saarlandes
Observational
30
Homburg
2026-09-01
Recruiting
Creating Encounters Between Generations - Together Instead of Alone (GemsE)
NCT07581171Loneliness, Mental Well-being, Health-related Quality of Life
Universitätsklinikum Hamburg-Eppendorf
Not applicable
80
Hamburg
2026-09-01
Not yet open
A Study of Mezagitamab in Adults With Late Antibody-Mediated Rejection (AMR) After a Kidney Transplant
NCT07613359Antibody-Mediated Rejection (AMR)
DrugMezagitamab
Takeda
Phase 2
36
Bochum, Essen, München, Münster
2026-09-01
Recruiting
A Study to Test How Well Different and Multiple Doses of BI 3034701 Are Tolerated in People Living With Overweight or Obesity
NCT07754474Overweight, Obesity
DrugBI 3034701
Boehringer Ingelheim
Phase 1
70
Mannheim
2026-09-01
Recruiting
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
NCT07624305Renal Insufficiency, Chronic
DrugsBalcinrenone/dapagliflozin·Dapagliflozin
AstraZeneca
Phase 3
2,800
Aachen, Bad Nenndorf, Berlin, Bonn, Brandenburg an der Havel, Braunschweig, Cloppenburg, Essen
2026-09-01
Not yet open
Paclitaxel, Ramucirumab and Tislelizumab Switch Maintenance in Advanced HER2-negative and PD-L1 TAP Score of 5 or More Advanced Gastroesophageal Adenocarcinoma
NCT07763171Gastroesophageal Adenocarcinoma
DrugsRamucirumab·Folfox·Tislelizumab·Paclitaxel
Gruppo Oncologico del Nord-Ovest
Phase 3
244
Frankfurt, Hamburg, München, Ulm
2026-09-01
Recruiting
A Study in Healthy Men to Find Out How Blocking Certain Transport Proteins Affects the Amount of BI 3000202 in the Blood
NCT07774325Healthy
DrugsBI 3000202·Ciclosporin·Itraconazole
Boehringer Ingelheim
Phase 1
16
Biberach
2026-09-01
Recruiting
Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD
NCT07010302NMOSD
DrugsSoliris·Satralizumab·Eculizumab·Inebilizumab
Massachusetts General Hospital
Phase 4
540
Berlin
2026-09-01
Not yet open
Mobile Geriatric Unit (MGU) to Reduce Hospitalisations in Nursing Home Residents
NCT07634757Nursing Home Care, Hospitalisation Prevention
Universität des Saarlandes
Observational
4,907
Homburg
2026-09-01
Not yet open
Combining Fasting and Fibre Interventions to Optimise Their Gut Microbiome-mediated Health Benefits
NCT07691736Fasting, Dietary Fibre, Gut Microbiome, Metabolism Changes
Buchinger Wilhelmi Development & Holding GmbH
Not applicable
75
Überlingen
2026-09-01
Recruiting
Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations
NCT07654855Transthyretin Amyloidosis, Transthyretin Amyloidosis With Cardiomyopathy, Transthyretin Amyloidosis With Polyneuropathy
AstraZeneca
Observational
320
Hanover
2026-09-01
Not yet open
Single-Shot Versus Focal Dual-Energy Pulsed Field-Based Ablation for Atrial Fibrillation
NCT07783919Atrial Fibrillation (AF)
Marien Hospital Herne
Not applicable
268
Herne
2026-09-01
Not yet open
Perioperative Role Of Vascular Endothelial Growth Factor In Cardiac Surgery-associated Acute Kidney Injury
NCT07803328Acute Kidney Injury, Cardiac Surgery Associated - Acute Kidney Injury
Universität Münster
Observational
220
Münster
2026-09-01
Not yet open
A Precision Medicine Trial for Patients With Relapsed or Refractory T Cell ALL
NCT07522801LAL
DrugsTofacitinib·Azacitidine·Venetoclax
Philippe ROUSSELOT
Phase 2
93
Frankfurt
2026-09-01
Not yet open
Flow-Controlled Ventilation to Improve Postoperative Pulmonary Outcome After Thoracic Surgery
NCT07623395Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs)
Cantonal Hospital of St. Gallen
Not applicable
140
Bochum
2026-09-01
Not yet open
Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair
NCT07486167Congenital Heart Disease, Cardiopulmonary Bypass, Mechanical Ventilation, Peep Titration in Lung Protective Ventilation
Charite University, Berlin, Germany
Phase 1/2
80
Berlin
2026-09-01
Not yet open
Catheter Ablation for AF in Patients With Severe Mitral Regurgitation After Successful Transcatheter Mitral-Valve Repair
NCT07380932Atrial Fibrillation (AF), Mitral Valve (MV) Regurgitation
Atrial Fibrillation Network
Not applicable
956
Cologne, Frankfurt, Hamburg, Münster
2026-09-01
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 Skipping
NCT07587242Muscular Dystrophies, Muscular Dystrophies (Duchenne, Becker, Myotonic Dystrophy), Muscular Disorders, Atrophic, Muscular Disease
DrugAOC 1044
Avidity Biosciences, Inc.
Phase 3
70
Essen, Heidelberg, München
2026-09-01
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site. Derived from ClinicalTrials.gov. Retrieved 26 September 2026. https://priyalifescience.com/clinical-trials-germany

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,051 studies in total at the last sync on 26 Sep 2026, 19:51 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Germany?

2,882 of the 5,051 studies in this register are recruiting new participants as of the 26 Sep 2026, 19:51 UTC sync. A further 252 have not yet opened recruitment, 1,774 are active but closed to new participants, and 143 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase, 5,051 studies
PhaseStudiesRecruitingShare
Observational1,4451,00828.6%
Phase 31,34458326.6%
Not applicable97759519.3%
Phase 263631012.6%
Phase 1/22391504.7%
Phase 12081084.1%
Phase 2/3108622.1%
Phase 488601.7%
Phase EARLY_PHASE1660.1%

Most active sponsors

Lead sponsors with the most studies
Lead sponsorStudiesRecruiting
AstraZeneca18592
Novartis Pharmaceuticals14258
Hoffmann-La Roche10136
Charite University, Berlin, Germany9974
Eli Lilly and Company9753
Merck Sharp & Dohme LLC9754
Janssen Research & Development, LLC8934
University Hospital Tuebingen8365
AbbVie7926
Universitätsklinikum Hamburg-Eppendorf7653

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Browse trials by condition

Breast Cancer (83) Heart Failure (70) Multiple Myeloma (68) Obesity (50) Coronary Artery Disease (43) Atrial Fibrillation (42) Prostate Cancer (42) Carcinoma, Non-Small-Cell Lung (36) Non-Small Cell Lung Cancer (36) Non-small Cell Lung Cancer (35) Ulcerative Colitis (32) Cancer (31) Multiple Sclerosis (30) Healthy (28) Atopic Dermatitis (28)
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Browse trials by site location

Berlin (1584) Hamburg (889) Essen (760) Dresden (707) Heidelberg (627) Cologne (612) Leipzig (511) München (508) Hanover (482) Tübingen (447) Düsseldorf (419) Bonn (413) Munich (405) Freiburg im Breisgau (384) Frankfurt (369)
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.