Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

Etentamig clinical trials

Also listed in trial records as ABBV-383, TNB-383B
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 13 trials in our USA, Japan, Germany, France, Australia, Israel, UK, Italy, Spain, Canada, Poland, Portugal, Norway, Belgium, Sweden, Denmark, Taiwan, Netherlands, China, Austria, Czechia, Turkey and South Korea registers that name Etentamig as an intervention. Synced 10 Nov 2026
13Current trials
6Recruiting now
2Lead sponsors
23Country registers
At a glance

Etentamig is named as an intervention in 13 current clinical trials in our USA, Japan, Germany, France, Australia, Israel, UK, Italy, Spain, Canada, Poland, Portugal, Norway, Belgium, Sweden, Denmark, Taiwan, Netherlands, China, Austria, Czechia, Turkey and South Korea registers. 6 are recruiting patients now. The most common phase is Phase 1/2. The sponsor with the most trials is AbbVie (12). The most-studied condition is Multiple Myeloma. The EU clinical trials register (CTIS) separately lists 1 authorised or ongoing trial.

How Etentamig works

All drug targets →
Diseases it has been tested for in clinical trials, by furthest phase
  • Plasma cell myelomaPhase 3
  • Waldenstrom macroglobulinemiaPhase 1/2
  • AmyloidosisPhase 1/2

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL5314973, CC BY-SA 3.0. The Guide to Pharmacology has no record of this medicine, so its targets rest on ChEMBL alone. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Etentamig

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting646%
  • Not yet open215%
  • Active, closed538%

Trials by phase

  • Phase 1/2538%
  • Phase 1538%
  • Phase 3215%
  • Phase 2/318%
01

Clinical trials of Etentamig

13 trials
StudyPhaseStatusLead sponsorRegisters
A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
NCT07095452 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 2/3 Recruiting AbbVie USA, France, Spain, Japan
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion
NCT06158854 · Immunoglobulin Light Chain (AL) Amyloidosis
Phase 1/2 Recruiting AbbVie USA, France, Italy, Japan, Australia
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
NCT06892522 · Multiple Myeloma
Phase 1/2 Recruiting AbbVie UK, USA, Norway, Japan, Australia, Israel
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
NCT06953960 · Multiple Myeloma
Phase 1/2 Recruiting AbbVie UK, USA, Germany, France, Italy, Belgium, Sweden, Poland, Portugal, Japan, Australia, Israel
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT05650632 · Multiple Myeloma
Phase 1 Recruiting AbbVie UK, USA, France, Spain, Denmark, Canada, Israel
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT06896916 · Multiple Myeloma
Phase 1 Recruiting AbbVie USA, France, Netherlands, Norway, Canada, Japan, Australia
A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma
NCT07728188 · Relapsed or Refractory Multiple Myeloma
Phase 3 Not yet open AbbVie UK, USA, Germany, France, Spain, Italy, Netherlands, Norway, Portugal, Canada, Taiwan, Australia, Israel
Etenta-Isa-VRd in Newly Diagnosed High-Risk Multiple Myeloma
NCT07600151 · ClinicalTrials.gov ↗ · Myeloma Multiple, Myeloma
Phase 1/2 Not yet open Universitätsklinikum Hamburg-Eppendorf Germany
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT06158841 · Multiple Myeloma
Phase 3 Active, closed AbbVie UK, USA, China, Germany, France, Spain, Italy, Belgium, Sweden, Denmark, Poland, Austria, Czechia, Portugal, Turkey, Canada, Japan, South Korea, Taiwan, Australia, Israel
A Study of TNB-383B in Participants With Relapsed or Refractory Multiple Myeloma
NCT03933735 · Multiple Myeloma
Phase 1/2 Active, closed AbbVie USA, Germany
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused Etentamig (ABBV-383) in Combination With Anti-Cancer Regimens for the Treatment of Adult Participants With Relapsed/Refractory Multiple Myeloma
NCT05259839 · Relapsed/Refractory Multiple Myeloma
Phase 1 Active, closed AbbVie USA, Germany, Spain, Italy, Poland, Japan, Australia
A Study to Assess Adverse Events and Change in Disease State of Intravenously (IV) Infused Etentamig (ABBV-383) of Adult Participants With Relapsed or Refractory Multiple Myeloma in Japan
NCT05286229 · ClinicalTrials.gov ↗ · Relapsed/Refractory Multiple Myeloma
Phase 1 Active, closed AbbVie Japan
Study of ABBV-383 Assessing Adverse Events and Clinical Activity With Subcutaneous (SC) Injection in Adult Participants With Relapsed or Refractory Multiple Myeloma
NCT06223516 · Multiple Myeloma
Phase 1 Active, closed AbbVie USA, Germany, Japan, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Etentamig in the EU trials register (CTIS)

1 trial

Authorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Etentamig. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.

StudyPhaseStatusSponsorCountries
A Phase 1/2, Open-Label, Platform Study to Evaluate Safety and Efficacy of the BCL-2 Inhibitor Surzetoclax (ABBV-453) given as Monotherapy or in Combination with Antimyeloma Regimens in Subjects with Multiple Myeloma
2025-525105-20-00 · Neoplasms
Phase 1 Ongoing AbbVie Deutschland GmbH & Co. KG Germany, Poland, Czechia + 6 more
03

Conditions studied with Etentamig

6 conditions
Multiple Myeloma8Relapsed/Refractory Multiple Myeloma2Relapsed or Refractory Multiple Myeloma1Immunoglobulin Light Chain (AL) Amyloidosis1Myeloma Multiple1Myeloma1
06

Related compounds

07

Questions about Etentamig trials

How many clinical trials are testing Etentamig?

13 current trials in our USA, Japan, Germany, France, Australia, Israel, UK, Italy, Spain, Canada, Poland, Portugal, Norway, Belgium, Sweden, Denmark, Taiwan, Netherlands, China, Austria, Czechia, Turkey and South Korea registers name Etentamig (also registered as ABBV-383) as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.

Are Etentamig trials recruiting patients?

Yes. 6 of the 13 trials are recruiting: 6 with sites in USA, 5 with sites in Japan, 1 with sites in Germany, 5 with sites in France, 4 with sites in Australia, 3 with sites in Israel, 3 with sites in UK, 2 with sites in Italy, 2 with sites in Spain, 2 with sites in Canada, 1 with sites in Poland, 1 with sites in Portugal, 2 with sites in Norway, 1 with sites in Belgium, 1 with sites in Sweden, 1 with sites in Denmark and 1 with sites in Netherlands. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Etentamig clinical trials?

AbbVie (12) and Universitätsklinikum Hamburg-Eppendorf (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Etentamig works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Etentamig works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Etentamig (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.