| NCT05020236 |
A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Recruiting |
Pfizer |
UK, USA, China |
| NCT05519085 |
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (ClinicalTrials.gov ↗) Relapsed or Refractory Multiple Myeloma |
Phase 3 |
Recruiting |
Celgene |
Ireland, UK, USA, India, China |
| NCT05730036 |
A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Relapsed Refractory Multiple Myeloma (RRMM) |
Phase 3 |
Recruiting |
Regeneron Pharmaceuticals |
UK, USA |
| NCT06152575 |
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide) Multiple Myeloma |
Phase 3 |
Recruiting |
Pfizer |
UK, USA, China |
| NCT06464991 |
A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Recruiting |
Nanjing IASO Biotechnology Co., Ltd. |
China |
| NCT06615479 |
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2) Relapsed or Refractory Multiple Myeloma (RRMM) |
Phase 3 |
Recruiting |
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
UK, USA, China |
| NCT07138209 |
A Study Comparing QLS32015 Monotherapy Versus Pomalidomide, Dexamethasone (Pd) or Selinexor, Dexamethasone (Sd) in Participants With Relapsed or Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Relapsed or Refractory Multiple Myeloma |
Phase 3 |
Recruiting |
Qilu Pharmaceutical Co., Ltd. |
China |
| NCT07222761 |
A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM) (ClinicalTrials.gov ↗) Relapsed and/or Refractory Multiple Myeloma (RRMM) |
Phase 3 |
Recruiting |
Regeneron Pharmaceuticals |
UK, USA |
| NCT07391657 |
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4) (ClinicalTrials.gov ↗) Relapsed Refractory Multiple Myeloma |
Phase 3 |
Recruiting |
AstraZeneca |
UK, USA, China |
| NCT07452198 |
A Study of GR1803 Injection Versus Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Participants With Relapsed or Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Recruiting |
Genrix (Shanghai) Biopharmaceutical Co., Ltd. |
China |
| NCT07555938 |
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Recruiting |
Hoffmann-La Roche |
USA, China |
| NCT07579234 |
A Multicenter, Randomized, Open-label, Parallel-group, Controlled, Superiority Phase III Clinical Study Comparing the Efficacy and Safety of F182112 Versus Standard of Care in Patients With Relapsed or Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Relapsed or Refractory Multiple Myeloma (RRMM) |
Phase 3 |
Recruiting |
Shandong New Time Pharmaceutical Co., LTD |
China |
| NCT07623798 |
A Study in Participants With Relapsed or Refractory Multiple Myeloma for IBI3003 (ClinicalTrials.gov ↗) Relapsed or Refractory Multiple Myeloma |
Phase 3 |
Recruiting |
Innovent Biologics (Suzhou) Co. Ltd. |
China |
| NCT05348213 |
Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell Lymphoma (ClinicalTrials.gov ↗) Diffuse Large B Cell Lymphoma |
Phase 2 |
Recruiting |
Ruijin Hospital |
China |
| NCT06342466 |
Bortezomib, Pomalidomide, Dexamethasone for Systemic AL Amyloidosis (ClinicalTrials.gov ↗) Systemic Amyloidosis |
Phase 2 |
Recruiting |
Jin Lu, MD |
China |
| NCT07018050 |
Phase II Study of QLS32015 Combination Therapy in the Treatment of Multiple Myeloma (ClinicalTrials.gov ↗) Relapsed or Refractory Multiple Myeloma |
Phase 2 |
Recruiting |
Qilu Pharmaceutical Co., Ltd. |
China |
| NCT07096778 |
Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Multiple Myeloma Refractory, Multiple Myeloma in Relapse |
Phase 2 |
Recruiting |
CellCentric Ltd. |
UK, USA |
| NCT07227311 |
A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM) (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 2 |
Recruiting |
GlaxoSmithKline |
USA |
| NCT02343042 |
Selinexor and Backbone Treatments of Multiple Myeloma Patients (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 1/2 |
Recruiting |
Karyopharm Therapeutics Inc |
USA |
| NCT04068597 |
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies Haematological Malignancy, Acute Myeloid Leukemia, Non Hodgkin Lymphoma |
Phase 1/2 |
Recruiting |
CellCentric Ltd. |
UK, USA |
| NCT04643002 |
Isatuximab in Combination With Novel Agents in RRMM - Master Protocol (ClinicalTrials.gov ↗) Plasma Cell Myeloma Refractory |
Phase 1/2 |
Recruiting |
Sanofi |
USA |
| NCT04973605 |
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma (ClinicalTrials.gov ↗) Relapsed/Refractory Multiple Myeloma |
Phase 1/2 |
Recruiting |
BeOne Medicines |
UK, USA, China |
| NCT05714839 |
A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 1/2 |
Recruiting |
GlaxoSmithKline |
UK, USA, China |
| NCT06106945 |
AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma Multiple Myeloma |
Phase 1/2 |
Recruiting |
AstraZeneca |
USA, China |
| NCT06953960 |
A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM) (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 1/2 |
Recruiting |
AbbVie |
UK, USA |
| NCT04910568 |
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 1 |
Recruiting |
Genentech, Inc. |
UK, USA |
| NCT05137054 |
A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 1 |
Recruiting |
Regeneron Pharmaceuticals |
USA |
| NCT05651932 |
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma, Myeloma, Myeloma Multiple |
Phase 1 |
Recruiting |
K36 Therapeutics, Inc. |
USA |
| NCT06768489 |
A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma, Smoldering Multiple Myeloma, Immunoglobulin Light-chain Amyloidosis |
Phase 1 |
Recruiting |
Janssen Research & Development, LLC |
USA |
| NCT07257510 |
Pomalidomide Plus Orelabrutinib and Zuberitamab in Untreated Mantle Cell Lymphoma (ClinicalTrials.gov ↗) Mantle Cell Lymphoma (MCL), POZ |
Not applicable |
Recruiting |
Peking University Third Hospital |
China |
| NCT07569757 |
Clinical Study of TQB2934 Injection in Relapsed/Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Not yet open |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
China |
| NCT07728188 |
A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma Relapsed or Refractory Multiple Myeloma |
Phase 3 |
Not yet open |
AbbVie |
UK, USA |
| NCT05669989 |
International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab Plasma Cell Myeloma |
Phase 2 |
By invitation |
Sanofi |
USA, China |
| NCT03539744 |
A Study Designed to Evaluate the Safety and Efficacy of Venetoclax Plus Dexamethasone (VenDex) Compared With Pomalidomide Plus Dexamethasone (PomDex) in Participants With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma. (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Active, closed |
AbbVie |
UK, USA, China |
| NCT04181827 |
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA |
| NCT04484623 |
Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Active, closed |
GlaxoSmithKline |
UK, USA, China |
| NCT05083169 |
A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA, China |
| NCT05405166 |
SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM Plasma Cell Myeloma Recurrent |
Phase 3 |
Active, closed |
Sanofi |
UK, USA, China |
| NCT05438043 |
A Study of Daratumumab (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA, China |
| NCT05455320 |
A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA, China |
| NCT05572515 |
A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Relapsed or Refractory Multiple Myeloma |
Phase 3 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA, India, China |
| NCT06158841 |
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 3 |
Active, closed |
AbbVie |
UK, USA, China |
| NCT06208150 |
A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide Multiple Myeloma |
Phase 3 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA, India, China |
| NCT06413498 |
A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma Multiple Myeloma |
Phase 3 |
Active, closed |
Kite, A Gilead Company |
UK, USA |
| NCT04126200 |
Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM) (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 1/2 |
Active, closed |
GlaxoSmithKline |
USA |
| NCT04108195 |
A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma Multiple Myeloma |
Phase 1 |
Active, closed |
Janssen Research & Development, LLC |
USA |
| NCT04667663 |
CPD-DARA in Patients With Relapsed/Refractory Multiple Myeloma. Multiple Myeloma |
Phase 1 |
Active, closed |
Cancer Trials Ireland |
Ireland |
| NCT04722146 |
A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma (ClinicalTrials.gov ↗) Multiple Myeloma |
Phase 1 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA |
| NCT05050097 |
A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma Multiple Myeloma |
Phase 1 |
Active, closed |
Janssen Research & Development, LLC |
UK, USA |
| NCT05259839 |
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused Etentamig (ABBV-383) in Combination With Anti-Cancer Regimens for the Treatment of Adult Participants With Relapsed/Refractory Multiple Myeloma (ClinicalTrials.gov ↗) Relapsed/Refractory Multiple Myeloma |
Phase 1 |
Active, closed |
AbbVie |
USA |