|
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
|
Observational |
Recruiting |
2024-09 |
UK |
|
A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs
|
Phase 1/2 |
Recruiting |
2026-01 |
UK, USA, China |
|
OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
|
Observational |
Recruiting |
2023-08 |
UK, USA, China |
iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases
NCT03549754 · Type 2 Diabetes, Hypertension, Chronic Kidney Disease
|
Observational |
Recruiting |
2018-02 |
India |
|
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
|
Phase 3 |
Recruiting |
2025-12 |
UK, USA, India, China |
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
NCT07444567 · Asthma, Eosinophilic Granulomatosis With Polyangiitis (EGPA), Hypereosinophilic Syndrome (HES)
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, India |
A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies
NCT06564038 · Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma, Mantle-cell Lymphoma
|
Phase 1/2 |
Recruiting |
2025-01 |
UK, USA, China |
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC
NCT07720284 · High-risk Muscle Invasive Urothelial Carcinoma
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, India, China |
Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
NCT05624450 · Viral Lung Infection and Acute Respiratory Failure
|
Phase 3 |
Recruiting |
2022-12 |
UK, USA, India, China |
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
NCT06283966 · COPD (Chronic Obstructive Pulmonary Disease)
|
Phase 3 |
Recruiting |
2024-02 |
UK, USA, India, China |
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
NCT07044336 · Endometrial Cancer, Malignant Solid Tumour
|
Phase 3 |
Recruiting |
2025-08 |
UK, USA, China |
|
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
|
Phase 3 |
Recruiting |
2024-04 |
UK, USA, India, China |
|
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
|
Phase 1 |
Recruiting |
2026-03 |
UK, USA |
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
NCT07611110 · Metastatic Castration-resistant Prostate Cancer
|
Phase 3 |
Recruiting |
2026-05 |
UK, USA, India, China |
|
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
|
Phase 3 |
Recruiting |
2024-11 |
UK, USA, India, China |
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
NCT07431281 · Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Esophageal Cancer
|
Phase 3 |
Recruiting |
2026-02 |
UK, USA, India, China |
Drug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
NCT07402915 · Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal
|
Phase 1 |
Recruiting |
2026-01 |
Ireland |
A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT06417814 · ClinicalTrials.gov ↗ · Metastatic Non-small Cell Lung Cancer
|
Phase 3 |
Recruiting |
2024-10 |
UK, USA, India, China |
A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients
NCT06549595 · ClinicalTrials.gov ↗ · Untreated Follicular Lymphoma
|
Phase 3 |
Recruiting |
2024-08 |
UK, USA, India, China |
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
NCT07662135 · ClinicalTrials.gov ↗ · Type 2 Diabetes Mellitus, Type 2 Diabetes With Chronic Kidney Disease
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, India, China |
Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab
NCT07024706 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
|
Phase 2 |
Recruiting |
2026-06 |
Ireland, USA |
A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT06879041 · Metastatic Castration-Resistant Prostate Cancer
|
Phase 1 |
Recruiting |
2025-03 |
USA |
The Prevalence of COPD in Patients With Cardiovascular Disease and the Benefit of Cardiopulmonary Co-management
NCT06909773 · ClinicalTrials.gov ↗ · Cardiovascular Diseases
|
Not applicable |
Recruiting |
2025-11 |
China |
|
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
|
Phase 2 |
Recruiting |
2026-02 |
UK, USA |
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
NCT06350097 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
|
Phase 3 |
Recruiting |
2024-04 |
USA, India, China |
AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer
NCT07218809 · ClinicalTrials.gov ↗ · Epithelial Ovarian Cancer
|
Phase 3 |
Recruiting |
2025-12 |
Ireland, UK, USA, India, China |
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
NCT06868277 · ClinicalTrials.gov ↗ · Carcinoma, Non-Small Cell Lung
|
Phase 3 |
Recruiting |
2025-04 |
Ireland, UK, USA, China |
|
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
|
Phase 2 |
Recruiting |
2025-03 |
USA, India, China |
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
NCT07624305 · ClinicalTrials.gov ↗ · Renal Insufficiency, Chronic
|
Phase 3 |
Recruiting |
2026-09 |
UK, USA, India |
|
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
|
Phase 3 |
Recruiting |
2023-11 |
UK, USA, India, China |
AZD5305 hADME in Patients With Advanced Solid Malignancies
NCT06713369 · Locally Advanced or Metastatic Solid Tumor
|
Phase 1 |
Recruiting |
2025-04 |
UK |
|
A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.
|
Phase 1/2 |
Recruiting |
2024-09 |
USA, China |
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
NCT06750289 · ClinicalTrials.gov ↗ · Eosinophilic Asthma
|
Phase 3 |
Recruiting |
2025-03 |
Ireland, UK, USA, China |
|
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
|
Phase 1/2 |
Recruiting |
2022-06 |
UK, USA |
|
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
|
Phase 1/2 |
Recruiting |
2025-10 |
UK, USA, China |
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
NCT07761117 · ClinicalTrials.gov ↗ · Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
|
Phase 3 |
Recruiting |
2026-08 |
UK, USA, India, China |
A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization
NCT07088926 · Bronchiectasis With Pseudomonas Aeruginosa Colonization
|
Phase 2 |
Recruiting |
2025-11 |
UK, USA |
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
NCT05797168 · Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer
|
Phase 1/2 |
Recruiting |
2023-06 |
UK, USA, China |
A Study of AZD0120 in Autoimmune Diseases
NCT07295847 · Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Rheumatoid Arthritis
|
Phase 1 |
Recruiting |
2026-01 |
UK, USA |
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin
NCT07664553 · ClinicalTrials.gov ↗ · Type 2 Diabetes Mellitus
|
Phase 3 |
Recruiting |
2026-07 |
USA, India, China |
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 · ClinicalTrials.gov ↗ · Chronic Kidney Disease and Hypertension
|
Phase 3 |
Recruiting |
2025-03 |
UK, USA, India, China |
|
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
|
Phase 3 |
Recruiting |
2026-06 |
UK, USA, India, China |
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
NCT07000357 · ClinicalTrials.gov ↗ · Cardiovascular Disease
|
Phase 3 |
Recruiting |
2025-06 |
UK, USA, India, China |
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
NCT06764875 · ClinicalTrials.gov ↗ · HER2-positive Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
|
Phase 3 |
Recruiting |
2025-03 |
UK, USA, India, China |
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
NCT05061550 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
|
Phase 2 |
Recruiting |
2022-04 |
Ireland, USA |
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
NCT06921785 · ClinicalTrials.gov ↗ · Hepatocellular Carcinoma
|
Phase 3 |
Recruiting |
2025-05 |
UK, USA, India, China |
|
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
|
Phase 1/2 |
Recruiting |
2024-12 |
USA |
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
NCT07082738 · ClinicalTrials.gov ↗ · Chronic Obstructive Pulmonary Disease (COPD)
|
Phase 2 |
Recruiting |
2025-06 |
UK, USA, India, China |
|
Investigating the Effect of Itraconazole on the Pharmacokinetics of AZD4144 in Healthy Participants
|
Phase 1 |
Recruiting |
2026-07 |
UK |
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
NCT07753993 · ClinicalTrials.gov ↗ · Chronic Kidney Disease
|
Phase 3 |
Recruiting |
2026-08 |
UK, USA, India, China |
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
NCT06137118 · ClinicalTrials.gov ↗ · B-cell Acute Lymphoblastic Leukemia (B-ALL)
|
Phase 1/2 |
Recruiting |
2023-12 |
UK, USA, China |
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
NCT06467357 · ClinicalTrials.gov ↗ · Biliary Tract Cancer
|
Phase 3 |
Recruiting |
2024-08 |
UK, USA, India, China |
CHOICE:Decision Factor of EGFR-TKI in Chinese IV NSCLC
NCT07413757 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
|
Observational |
Recruiting |
2026-03 |
China |
|
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
|
Phase 3 |
Recruiting |
2025-03 |
UK, USA, India, China |
|
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
|
Phase 1/2 |
Recruiting |
2026-03 |
UK, USA |
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
NCT07784270 · ClinicalTrials.gov ↗ · Obesity or Overweight, Diabetes Mellitus, Type 2
|
Phase 3 |
Recruiting |
2026-08 |
UK, USA, India, China |
|
An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia
|
Phase 3 |
Recruiting |
2019-04 |
UK, USA, India, China |
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
NCT07276581 · ClinicalTrials.gov ↗ · Rheumatoid Arthritis
|
Phase 2 |
Recruiting |
2025-12 |
UK, USA, China |
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
NCT07291037 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer (NSCLC)
|
Phase 3 |
Recruiting |
2025-10 |
UK, USA, India, China |
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
NCT07784725 · ClinicalTrials.gov ↗ · Obesity or Overweight
|
Phase 3 |
Recruiting |
2026-08 |
USA, India, China |
An Open-label Study of AZD0120 in Adults With Multiple Sclerosis
NCT07224373 · ClinicalTrials.gov ↗ · Multiple Sclerosis
|
Phase 1 |
Recruiting |
2025-12 |
UK, USA |
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
NCT05774951 · ClinicalTrials.gov ↗ · Breast Cancer, Early Breast Cancer
|
Phase 3 |
Recruiting |
2023-03 |
UK, USA, India, China |
|
An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.
|
Phase 4 |
Recruiting |
2026-06 |
USA |
|
A Modular, Phase I/II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma
|
Phase 1/2 |
Recruiting |
2026-07 |
USA |
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
NCT06380751 · ClinicalTrials.gov ↗ · Advanced Breast Cancer
|
Phase 3 |
Recruiting |
2024-08 |
UK, USA, India, China |
|
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
|
Phase 3 |
Recruiting |
2026-07 |
USA, China |
|
AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma
|
Phase 1/2 |
Recruiting |
2023-12 |
USA, China |
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
NCT06129864 · ClinicalTrials.gov ↗ · Locally Advanced Head and Neck Squamous Cell Carcinoma
|
Phase 3 |
Recruiting |
2023-12 |
UK, USA, India, China |
|
A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer
|
Phase 3 |
Recruiting |
2025-10 |
USA, China |
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
NCT06883305 · ClinicalTrials.gov ↗ · Chronic Obstructive Pulmonary Disease (COPD)
|
Phase 3 |
Recruiting |
2025-03 |
UK, USA, India, China |
A Phase I/II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
NCT07123454 · ClinicalTrials.gov ↗ · B-cell Non-Hodgkin Lymphoma
|
Phase 1/2 |
Recruiting |
2025-09 |
UK, USA, China |
A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism
NCT07007793 · ClinicalTrials.gov ↗ · Primary Hyperaldosteronism
|
Phase 3 |
Recruiting |
2025-08 |
UK, USA, India, China |
|
Study of Safety and PK of AZD0543 in Healthy Adults
|
Phase 1 |
Recruiting |
2026-08 |
USA |
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652 · ClinicalTrials.gov ↗ · Heart Failure and Impaired Kidney Function
|
Phase 3 |
Recruiting |
2024-04 |
UK, USA, India, China |
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
NCT07662109 · ClinicalTrials.gov ↗ · Type 2 Diabetes Mellitus
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, India, China |
Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
NCT04686305 · Locally Advanced or Metastatic Non-Small Cell Lung Cancer
|
Phase 1 |
Recruiting |
2021-03 |
USA, China |
|
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
|
Phase 3 |
Recruiting |
2025-08 |
UK, USA, India, China |
A Trial to Investigate Benralizumab in Children With Eosinophilic Diseases
NCT06512883 · ClinicalTrials.gov ↗ · Eosinophilic Granulomatosis With Polyangiitis (EGPA), Hypereosinophilia Syndrome (HES)
|
Phase 3 |
Recruiting |
2025-04 |
USA, India |
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
NCT06651970 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukaemia, Moderate to Severe Cardiac Impairment
|
Phase 4 |
Recruiting |
2025-02 |
UK, USA |
Post-marketing Phase 4 Safety & Tolerability Study of Breztri aerosphereTM in Indian Patients With Chronic Obstructive Pulmonary Disease
NCT06531798 · ClinicalTrials.gov ↗ · Moderate to Severe COPD
|
Phase 4 |
Recruiting |
2026-01 |
India |
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
NCT06692738 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
|
Phase 3 |
Recruiting |
2024-11 |
UK, USA, India, China |
Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)
NCT06079671 · ClinicalTrials.gov ↗ · Locally Advanced Cervical Cancer
|
Phase 3 |
Recruiting |
2023-09 |
USA, India, China |
Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer
NCT07427394 · ClinicalTrials.gov ↗ · Advanced Breast Cancer
|
Phase 2 |
Recruiting |
2026-05 |
UK, USA |
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)
NCT06455449 · ClinicalTrials.gov ↗ · Polymyositis, Dermatomyositis
|
Phase 3 |
Recruiting |
2024-06 |
UK, USA, India, China |
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
NCT07662213 · ClinicalTrials.gov ↗ · Type 2 Diabetes Mellitus
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, China |
|
A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies
|
Observational |
Recruiting |
2026-05 |
USA, India |
AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL
NCT07215585 · ClinicalTrials.gov ↗ · Large B-cell Lymphoma
|
Phase 3 |
Recruiting |
2025-11 |
UK, China |
A Study of MET Concordance and Gene Profiling in 1L NSCLC (Genomet)
NCT07613424 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
|
Not applicable |
Recruiting |
2026-06 |
China |
A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
NCT06188520 · ClinicalTrials.gov ↗ · ER+ HER2- Advanced Breast Cancer, High-grade Serous Ovarian Cancer (HGSOC)
|
Phase 1/2 |
Recruiting |
2023-12 |
UK, USA |
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
NCT06916806 · ClinicalTrials.gov ↗ · Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies, Rheumatoid Arthritis
|
Phase 1 |
Recruiting |
2025-05 |
UK, USA, China |
A Study of AZD2962, an IRAK4 Inhibitor (IRAK4 [a Body Protein] Blocker), in Participants With Haematologic Neoplasms (Blood Cancers)
NCT07064122 · ClinicalTrials.gov ↗ · Haematologic Neoplasms
|
Phase 1 |
Recruiting |
2025-11 |
UK, USA |
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
NCT06465810 · ClinicalTrials.gov ↗ · Transthyretin Amyloidosis, ATTR-CM, ATTRv-PN
|
Observational |
Recruiting |
2024-06 |
UK, USA, China |
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
NCT07201558 · ClinicalTrials.gov ↗ · Rheumatoid Arthritis, Systemic Lupus Erythematosus
|
Phase 1 |
Recruiting |
2025-12 |
UK, USA, China |
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
NCT05489211 · ClinicalTrials.gov ↗ · Endometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer
|
Phase 2 |
Recruiting |
2022-09 |
UK, USA, China |
Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)
NCT07509151 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated IGHV
|
Phase 3 |
Recruiting |
2026-05 |
UK, USA |
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
NCT06897930 · ClinicalTrials.gov ↗ · Lupus Erythematosus, Systemic
|
Phase 1/2 |
Recruiting |
2025-04 |
UK, USA |
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
NCT06989112 · ClinicalTrials.gov ↗ · Endometrial Cancer
|
Phase 3 |
Recruiting |
2025-03 |
UK, USA, China |
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
NCT05123482 · ClinicalTrials.gov ↗ · Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer
|
Phase 1/2 |
Recruiting |
2021-10 |
UK, USA, China |
Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom
NCT05557695 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia, CLL
|
Observational |
Recruiting |
2022-10 |
UK |
|
A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma
|
Phase 3 |
Recruiting |
2024-06 |
China |