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Compound · clinical trials

AZD0120 clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 9 trials in our USA, UK and China registers that name AZD0120 as an intervention. Synced 25 Sep 2026
9Current trials
8Recruiting now
3Lead sponsors
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

AZD0120 is named as an intervention in 9 current clinical trials in our USA, UK and China registers. 8 are recruiting patients now. The most common phase is Phase 1/2. The sponsor with the most trials is AstraZeneca (7). The most-studied condition is Lupus Erythematosus, Systemic.

Trials by status

  • Recruiting889%
  • Not yet open111%

Trials by phase

  • Phase 1/2333%
  • Phase 3333%
  • Phase 1222%
  • Phase EARLY_PHASE1111%
01

Clinical trials of AZD0120

9 trials
StudyPhaseStatusLead sponsorRegisters
CAR-T Therapy Targeting CD19 and BCMA in Highly Sensitized Kidney Transplant Participants
NCT07350837 · ClinicalTrials.gov ↗ · Highly Sensitized Patients Awaiting Kidney Transplant
Phase EARLY_PHASE1 Recruiting Tongji Hospital China
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)
NCT07391657 · ClinicalTrials.gov ↗ · Relapsed Refractory Multiple Myeloma
Phase 3 Recruiting AstraZeneca UK, USA, China
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
NCT07764978 · ClinicalTrials.gov ↗ · Newly Diagnosed Multiple Myeloma
Phase 3 Recruiting AstraZeneca UK, USA
AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)
NCT05850234 · ClinicalTrials.gov ↗ · Relapsed/Refractory Multiple Myeloma
Phase 1/2 Recruiting AstraZeneca USA
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
NCT06897930 · ClinicalTrials.gov ↗ · Lupus Erythematosus, Systemic
Phase 1/2 Recruiting AstraZeneca UK, USA
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
NCT07081646 · ClinicalTrials.gov ↗ · Relapsed AL Amyloidosis, Refractory AL Amyloidosis, Light Chain Amyloidosis
Phase 1/2 Recruiting Alexion Pharmaceuticals, Inc. UK, USA
A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)
NCT07073547 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 1 Recruiting AstraZeneca USA
A Study of AZD0120 in Autoimmune Diseases
NCT07295847 · ClinicalTrials.gov ↗ · Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Rheumatoid Arthritis
Phase 1 Recruiting AstraZeneca UK, USA
A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).
NCT07735637 · ClinicalTrials.gov ↗ · Newly Diagnosed Multiple Myeloma (NDMM)
Phase 3 Not yet open AstraZeneca UK, USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with AZD0120

14 conditions
Lupus Erythematosus, Systemic1Newly Diagnosed Multiple Myeloma (NDMM)1Systemic Sclerosis1Idiopathic Inflammatory Myopathies1Rheumatoid Arthritis1Newly Diagnosed Multiple Myeloma1Relapsed Refractory Multiple Myeloma1Relapsed AL Amyloidosis1Refractory AL Amyloidosis1Light Chain Amyloidosis1Amyloidosis1Multiple Myeloma1
All 14 conditions
Condition (as registered)Trials
Lupus Erythematosus, Systemic1
Newly Diagnosed Multiple Myeloma (NDMM)1
Systemic Sclerosis1
Idiopathic Inflammatory Myopathies1
Rheumatoid Arthritis1
Newly Diagnosed Multiple Myeloma1
Relapsed Refractory Multiple Myeloma1
Relapsed AL Amyloidosis1
Refractory AL Amyloidosis1
Light Chain Amyloidosis1
Amyloidosis1
Multiple Myeloma1
Relapsed/Refractory Multiple Myeloma1
Highly Sensitized Patients Awaiting Kidney Transplant1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
AstraZeneca7
Alexion Pharmaceuticals, Inc.1
Tongji Hospital1
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA87
Clinical trials in UK65
Clinical trials in China22

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about AZD0120 trials

How many clinical trials are testing AZD0120?

9 current trials in our USA, UK and China registers name AZD0120 as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are AZD0120 trials recruiting patients?

Yes. 8 of the 9 trials are recruiting: 7 with sites in USA, 5 with sites in UK and 2 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors AZD0120 clinical trials?

AstraZeneca (7), Alexion Pharmaceuticals, Inc (1) and Tongji Hospital (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how AZD0120 works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how AZD0120 works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists AZD0120 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.