| NCT06831370 |
A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in India (ClinicalTrials.gov ↗) Hodgkin Lymphoma |
Phase 4 |
Recruiting |
Takeda |
India |
| NCT01704716 |
High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN) (ClinicalTrials.gov ↗) Neuroblastoma |
Phase 3 |
Recruiting |
St. Anna Kinderkrebsforschung |
Ireland |
| NCT04043494 |
International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma (ClinicalTrials.gov ↗) Lymphoblastic Lymphoma, Childhood |
Phase 3 |
Recruiting |
University Hospital Muenster |
Ireland, China |
| NCT04638790 |
First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1) Hodgkin Lymphoma, Adult |
Phase 3 |
Recruiting |
State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia |
India |
| NCT04685616 |
Brentuximab Vedotin in Early Stage Hodgkin Lymphoma (ClinicalTrials.gov ↗) Hodgkin Lymphoma |
Phase 3 |
Recruiting |
University College, London |
Ireland |
| NCT06091254 |
A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma Follicular Lymphoma (FL) |
Phase 3 |
Recruiting |
Regeneron Pharmaceuticals |
UK, USA |
| NCT06091865 |
A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma (ClinicalTrials.gov ↗) Diffuse Large B-cell Lymphoma (DLBCL) |
Phase 3 |
Recruiting |
Regeneron Pharmaceuticals |
Ireland, UK, USA |
| NCT06340568 |
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer Endometrial Cancer |
Phase 3 |
Recruiting |
BioNTech SE |
UK, USA, China |
| NCT06394492 |
SHR-A1921 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer (ClinicalTrials.gov ↗) Ovarian Cancer |
Phase 3 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06584032 |
Study of Fruquintinib Plus Sintilimab for Treatment of Advanced Endometrial Cancer (ClinicalTrials.gov ↗) Advanced Endometrial Cancer |
Phase 3 |
Recruiting |
Hutchmed |
China |
| NCT06717347 |
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010) (ClinicalTrials.gov ↗) Diffuse Large B-Cell Lymphoma |
Phase 3 |
Recruiting |
Merck Sharp & Dohme LLC |
USA, China |
| NCT06855069 |
HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer (ClinicalTrials.gov ↗) Ovarian Cancer |
Phase 3 |
Recruiting |
Hansoh BioMedical R&D Company |
China |
| NCT06911502 |
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4) (ClinicalTrials.gov ↗) Follicular Lymphoma |
Phase 3 |
Recruiting |
Celgene |
UK, USA, India, China |
| NCT06966700 |
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032) (ClinicalTrials.gov ↗) Breast Neoplasms, Triple Negative Breast Neoplasms, HR Low-Positive/HER2-Negative Breast Neoplasms |
Phase 3 |
Recruiting |
Merck Sharp & Dohme LLC |
UK, USA, India, China |
| NCT07044336 |
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01) (ClinicalTrials.gov ↗) Endometrial Cancer, Malignant Solid Tumour |
Phase 3 |
Recruiting |
AstraZeneca |
UK, USA, China |
| NCT07441460 |
A Phase III Study of KN026 in Combination With HB1801 as Adjuvant Therapy for Resectable HER2-Positive Breast Cancer (ClinicalTrials.gov ↗) Resectable HER2-positive Breast Cancer |
Phase 3 |
Recruiting |
Shanghai JMT-Bio Inc. |
China |
| NCT06563245 |
Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment (ClinicalTrials.gov ↗) Classical Hodgkin Lymphoma, Child, Adolescent |
Phase 2/3 |
Recruiting |
Children's Cancer Group, China |
China |
| NCT06277154 |
MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma (ClinicalTrials.gov ↗) Leiomyosarcoma, Liposarcoma, Synovial Sarcoma |
Phase 2 |
Recruiting |
HRYZ Biotech Co. |
China |
| NCT06704555 |
Radiotherapy Followed by Tiselizumab Combined With RCHOP in Previously Untreated Bulky Follicular Lymphoma (ClinicalTrials.gov ↗) Follicular Lymphoma |
Phase 2 |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
| NCT06803693 |
Efficacy and Safety of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL (ClinicalTrials.gov ↗) Diffuse Large B-Cell Lymphoma |
Phase 2 |
Recruiting |
Ruijin Hospital |
China |
| NCT06890884 |
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011) (ClinicalTrials.gov ↗) Lymphoma, Large B-Cell, Diffuse |
Phase 2 |
Recruiting |
Merck Sharp & Dohme LLC |
Ireland, UK, USA |
| NCT04432714 |
Lenalidomide in Combination With R-DA-EPOCH in Patients With Untreated DLBCL With MYC Rearrangement (ClinicalTrials.gov ↗) DLBCL, Untreated, MYC Gene Rearrangement |
Phase 1/2 |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
| NCT04625907 |
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma (ClinicalTrials.gov ↗) Rhabdomyosarcoma |
Phase 1/2 |
Recruiting |
University of Birmingham |
Ireland |
| NCT05824975 |
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) (ClinicalTrials.gov ↗) Advanced Solid Tumor, Metastatic Solid Tumor, Soft Tissue Sarcoma (STS) |
Phase 1/2 |
Recruiting |
GI Innovation, Inc. |
USA |
| NCT05981014 |
Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer (ClinicalTrials.gov ↗) Breast Neoplasms |
Phase 1/2 |
Recruiting |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
China |
| NCT06564038 |
A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma, Mantle-cell Lymphoma |
Phase 1/2 |
Recruiting |
AstraZeneca |
UK, USA, China |
| NCT07124936 |
A Study of HDM2005 in Combination With Standard of Care in Patients With Diffuse Large B-Cell Lymphoma (ClinicalTrials.gov ↗) Diffuse Large B Cell Lymphoma (DLBCL) |
Phase 1/2 |
Recruiting |
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. |
China |
| NCT05785754 |
DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors (ClinicalTrials.gov ↗) Advanced or Metastatic Solid Tumors |
Phase 1 |
Recruiting |
DynamiCure Biotechnology |
USA |
| NCT06121570 |
Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer (ClinicalTrials.gov ↗) Breast Neoplasms |
Phase 1 |
Recruiting |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
China |
| NCT07719855 |
A Multicenter, Prospective, Open-Label, Randomized Controlled Clinical Study of Orelabrutinib Combined With Obinutuzumab and Lenalidomide Versus Obinutuzumab Plus Chemotherapy for Treatment-Naive Follicular Lymphoma (ClinicalTrials.gov ↗) Follicular Lymphoma ( FL) |
Phase 3 |
Not yet open |
Ruijin Hospital |
China |
| NCT07712588 |
Birelentinib Plus R-CHOP in Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma (TAI-SHAN19) (ClinicalTrials.gov ↗) Diffuse Large B-Cell Lymphoma (DLBCL) |
Phase 2/3 |
Not yet open |
Dizal Pharmaceuticals |
China |
| NCT06713057 |
Efficacy of Organoid-Based Chemotherapy Drug Precision Screening to Guide Treatment for Thyroid Cancer (ClinicalTrials.gov ↗) Locally Advanced Thyroid Gland Carcinoma, Thyroid Cancer |
Phase 2 |
Not yet open |
West China Hospital |
China |
| NCT07231250 |
Glofitamab Plus Polatuzumab Vedotin and Zuberitamab in Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma (ClinicalTrials.gov ↗) DLBCL - Diffuse Large B Cell Lymphoma, Chemo-free Therapy, Bispecific Antibody |
Phase 2 |
Not yet open |
Li Zhiming |
China |
| NCT07594899 |
AI-Driven Treatment Strategy vs Pola-R-CHP in Untreated LBCL (ClinicalTrials.gov ↗) Large B-Cell Lymphoma (LBCL) |
Phase 2 |
Not yet open |
Ruijin Hospital |
China |
| NCT07638787 |
Pola-R-CHP Plus Sonrotoclax in Untreated BCL2-High/Double-Hit LBCL (ClinicalTrials.gov ↗) Large B-cell Lymphoma |
Phase 1/2 |
Not yet open |
Ruijin Hospital |
China |
| NCT05287308 |
Adjuvant Albumin-bound Paclitaxel Versus Taxanes in Breast Cancer: a Real-world Study (ClinicalTrials.gov ↗) Breast Cancer |
Not applicable |
Not yet open |
Chinese Academy of Medical Sciences |
China |
| NCT06468943 |
Polatuzumab Vedotin and Zanubrutinib Plus R-CHP for Patients With Newly Diagnosed Untreated Non-GCB DLBCL (ClinicalTrials.gov ↗) Effects of Chemotherapy, Safety Issues |
Phase 2 |
By invitation |
The First Affiliated Hospital of Soochow University |
China |
| NCT03017326 |
Paediatric Hepatic International Tumour Trial (ClinicalTrials.gov ↗) Hepatoblastoma, Carcinoma, Hepatocellular |
Phase 3 |
Active, closed |
University of Birmingham |
Ireland |
| NCT03725059 |
Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756) Breast Cancer |
Phase 3 |
Active, closed |
Merck Sharp & Dohme LLC |
Ireland, UK, USA, China |
| NCT04529772 |
A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312) (ClinicalTrials.gov ↗) Diffuse Large B-Cell Lymphoma |
Phase 3 |
Active, closed |
Acerta Pharma BV |
USA, India, China |
| NCT04824092 |
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients (ClinicalTrials.gov ↗) Diffuse Large B-cell Lymphoma |
Phase 3 |
Active, closed |
Incyte Corporation |
Ireland, UK, USA |
| NCT05113251 |
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer (ClinicalTrials.gov ↗) Breast Neoplasms, Breast Cancer, HER2-positive Early Breast Cancer |
Phase 3 |
Active, closed |
AstraZeneca |
USA, India, China |
| NCT05578976 |
A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) (ClinicalTrials.gov ↗) Diffuse Large B-Cell Lymphoma |
Phase 3 |
Active, closed |
Genmab |
UK, USA, China |
| NCT05605899 |
Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma (ClinicalTrials.gov ↗) High-risk Large B-cell Lymphoma (LBCL) |
Phase 3 |
Active, closed |
Kite, A Gilead Company |
UK, USA |
| NCT06047080 |
An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma (ClinicalTrials.gov ↗) Large B-Cell Lymphoma |
Phase 3 |
Active, closed |
Hoffmann-La Roche |
UK, USA, China |
| NCT06088290 |
Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo) (ClinicalTrials.gov ↗) Leiomyosarcoma |
Phase 3 |
Active, closed |
PharmaMar |
UK, USA |
| NCT06097364 |
A Trial to Learn if Odronextamab Combined With Chemotherapy is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Chemotherapy for Adult Participants With Follicular Lymphoma (ClinicalTrials.gov ↗) Follicular Lymphoma (FL) |
Phase 3 |
Active, closed |
Regeneron Pharmaceuticals |
UK, USA |
| NCT06112379 |
A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer (ClinicalTrials.gov ↗) Breast Cancer |
Phase 3 |
Active, closed |
AstraZeneca |
UK, USA, India, China |
| NCT06132958 |
Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005) (ClinicalTrials.gov ↗) Endometrial Cancer |
Phase 3 |
Active, closed |
Merck Sharp & Dohme LLC |
Ireland, UK, USA, China |
| NCT06191744 |
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma (ClinicalTrials.gov ↗) Follicular Lymphoma (FL) |
Phase 3 |
Active, closed |
Genmab |
UK, USA, China |
| NCT06356129 |
Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma (ClinicalTrials.gov ↗) Large B-cell Lymphoma |
Phase 3 |
Active, closed |
Celgene |
USA, India, China |
| NCT06486441 |
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26) (ClinicalTrials.gov ↗) Endometrial Cancer |
Phase 3 |
Active, closed |
Gilead Sciences |
UK, USA, China |
| NCT02641847 |
TA(E)C-GP Versus A(E)C-T for the High Risk TNBC Patients and Validation of the mRNA-lncRNA Signature (ClinicalTrials.gov ↗) Triple Negative Breast Cancer, Breast Cancer |
Phase 2/3 |
Active, closed |
Fudan University |
China |
| NCT03407144 |
Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667) (ClinicalTrials.gov ↗) Hodgkin Lymphoma |
Phase 2 |
Active, closed |
Merck Sharp & Dohme LLC |
UK, USA |
| NCT03678883 |
9-ING-41 in Patients With Advanced Cancers (ClinicalTrials.gov ↗) Cancer, Pancreatic Cancer, Sarcoma |
Phase 2 |
Active, closed |
Actuate Therapeutics Inc. |
USA |
| NCT04980222 |
A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma (ClinicalTrials.gov ↗) Lymphoma |
Phase 2 |
Active, closed |
Hoffmann-La Roche |
USA |
| NCT05673785 |
A Study of Brentuximab Vedotin in Combination With Cyclophosphamide, Doxorubicin (Hydroxydaunorubicin), Prednisone (CHP) in Chinese Participants With CD30-Positive (CD30+) Peripheral T-Cell Lymphomas (PTCL) (ClinicalTrials.gov ↗) Lymphoma |
Phase 2 |
Active, closed |
Takeda |
China |
| NCT06425302 |
A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma (ClinicalTrials.gov ↗) Lymphoma, Follicular |
Phase 2 |
Active, closed |
Celgene |
UK, USA |
| NCT02979522 |
A Study of Brentuximab Vedotin + Adriamycin, Vinblastine, and Dacarbazine in Pediatric Participants With Advanced Stage Newly Diagnosed Hodgkin Lymphoma (ClinicalTrials.gov ↗) Hodgkin Disease |
Phase 1/2 |
Active, closed |
Takeda |
USA |
| NCT04008797 |
A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor (ClinicalTrials.gov ↗) Endometrial Neoplasms, Neoplasms, Carcinoma, Hepatocellular |
Phase 1/2 |
Active, closed |
Eisai Inc. |
USA, China |
| NCT05201248 |
A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin Lymphoma (ClinicalTrials.gov ↗) B-Cell Non-Hodgkin Lymphoma |
Phase 1/2 |
Active, closed |
Genmab |
China |
| NCT05630209 |
Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG) Brain Tumor |
Phase 1/2 |
Active, closed |
InSightec |
USA |
| NCT04884035 |
Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma (ClinicalTrials.gov ↗) Lymphoma, B-Cell |
Phase 1 |
Active, closed |
Celgene |
USA |