ChemoRT With and Without Dental Stent for Taste Protection in NPC Patients
NCT06733948 · ClinicalTrials.gov ↗ · Nasopharyngeal Carcinoma
|
Phase 2 |
Recruiting |
2024-09 |
Singapore |
Liquid Biopsy-Based Pre-Screening to Streamline LDCT Lung Cancer Screening in High-Risk Individuals
NCT07358715 · ClinicalTrials.gov ↗ · Lung Cancer, Lung Neoplasms, Early Lung Cancer Detection
|
Not applicable |
Recruiting |
2024-11 |
Singapore |
CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial
NCT06983769 · ClinicalTrials.gov ↗ · Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment
|
Not applicable |
Recruiting |
2026-01 |
Singapore |
Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease: The RESET Cohort Study
NCT06211868 · ClinicalTrials.gov ↗ · Cardiovascular Diseases, Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
|
Observational |
Recruiting |
2024-03 |
Singapore |
A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy - Expansion Study
NCT05606068 · ClinicalTrials.gov ↗ · Chemotherapy-induced Peripheral Neuropathy
|
Not applicable |
Recruiting |
2022-11 |
Singapore |
|
Alpha Ketoglutarate Enhances Geroprotection In Surgery (AEGIS)
|
Phase 4 |
Recruiting |
2024-06 |
Singapore |
Discharge Recommendations for Older Adults Using Physical Outcome Measure
NCT06903832 · ClinicalTrials.gov ↗ · Discharge Planning, Older Adults (65 Years and Older), Acute Hospitalization
|
Observational |
Recruiting |
2025-04 |
Singapore |
Implementation of Decade of Healthy Ageing Action Plan to Screen and Prevent Decline in Intrinsic Capacity in Elders (SPICE) Through Multisectoral Collaboration in Singapore
NCT07525583 · ClinicalTrials.gov ↗ · Frailty, Intrinsic Capacity, Lifestyle
|
Observational |
Recruiting |
2025-04 |
Singapore |
|
Cervical Cancer Brachytherapy With Interstitial Needles in 3 Fractions
|
Not applicable |
Recruiting |
2023-06 |
Singapore |
Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness
NCT07536035 · ClinicalTrials.gov ↗ · Falls Injury, Falls, Hospitalization in Acute Care
|
Observational |
Recruiting |
2024-09 |
Singapore |
Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies
NCT03772561 · ClinicalTrials.gov ↗ · Solid Tumor, Adult
|
Phase 1 |
Recruiting |
2018-12 |
Singapore |
Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis
NCT05473520 · Tuberculosis, Acute Coronary Syndrome, Pulmonary Hypertension (Diagnosis)
|
Phase 3 |
Recruiting |
2023-05 |
Singapore |
The MUSE Study for Menopausal Arthralgia
NCT06530459 · ClinicalTrials.gov ↗ · Arthralgia, Menopause, Perimenopausal Disorder
|
Phase 2/3 |
Recruiting |
2024-08 |
Singapore |
Adjunctive Doxycycline for Central Nervous System Tuberculosis
NCT06446245 · ClinicalTrials.gov ↗ · Tuberculosis, Meningeal, Tuberculosis; Meningitis (Etiology), Tuberculosis, Central Nervous System
|
Phase 2 |
Recruiting |
2025-08 |
Singapore |
Dupilumab Therapy in Nephrotic Syndrome in Children
NCT07091175 · ClinicalTrials.gov ↗ · Nephrotic Syndrome in Children, Nephrotic Syndrome Steroid-Dependent
|
Phase 2 |
Recruiting |
2025-11 |
Singapore |
ETC-159 In Combination With Pembrolizumab In Advanced MSS/pMMR Ovarian Cancers
NCT06513624 · ClinicalTrials.gov ↗ · With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer
|
Phase 1 |
Recruiting |
2024-12 |
Singapore |
Use of a Digital Psychotherapeutic App to Reduce Symptom Burden in Dermatology Patients
NCT06702293 · ClinicalTrials.gov ↗ · Eczema, Psoriasis, Urticaria
|
Not applicable |
Recruiting |
2026-02 |
Singapore |
Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC)
NCT06923826 · ClinicalTrials.gov ↗ · Salivary Gland Cancer, Thyroid Cancer
|
Phase 2 |
Recruiting |
2025-04 |
Singapore |
Singapore Perioperative Ageing Study (Sing-PAS)
NCT04792554 · ClinicalTrials.gov ↗ · Postoperative Delirium, Aging, Myocardial Injury
|
Observational |
Recruiting |
2021-04 |
Singapore |
|
Mepitel Film Breast
|
Observational |
Recruiting |
2025-11 |
Singapore |
A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
NCT06422403 · ClinicalTrials.gov ↗ · Carcinoma, Hepatocellular, Gastric Adenocarcinoma, GastroEsophageal Cancer
|
Phase 2 |
Recruiting |
2024-11 |
Singapore |
Evaluation of ex Vivo Drug Combination Optimization Platform in Recurrent High Grade Astrocytic Glioma
NCT05532397 · ClinicalTrials.gov ↗ · Glioma, Astrocytic
|
Not applicable |
Recruiting |
2023-02 |
Singapore |
Antigen Targeted T Cell Therapy for Relapsed/Refractory B Cell Lymphomas
NCT07319676 · ClinicalTrials.gov ↗ · B-cell Lymphoma Refractory
|
Phase 1/2 |
Recruiting |
2026-03 |
Singapore |
Reducing Delirium After CABG Surgery With Early Activation and Sleep-Promoting Routines
NCT06107517 · ClinicalTrials.gov ↗ · Delirium, Postoperative
|
Not applicable |
Recruiting |
2024-01 |
Singapore |
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
NCT07241221 · ClinicalTrials.gov ↗ · Perinatal and Neonatal Outcomes in Pregnancies With Type 2 Diabetes Mellitus (T2DM)
|
Not applicable |
Recruiting |
2025-12 |
Singapore |
StrataXRT vs Standard Clinical Practice for the Prevention of Acute Dermatitis in Head and Neck Cancers Patients
NCT03394417 · ClinicalTrials.gov ↗ · Head and Neck Cancers, Acute Radiation Dermatitis
|
Not applicable |
Recruiting |
2018-11 |
Singapore |
Selinexor & Talazoparib in Advanced Refractory Solid Tumors; Advanced/Metastatic Triple Negative Breast Cancer (START)
NCT05035745 · ClinicalTrials.gov ↗ · Advanced Refractory Solid Tumors, Advanced Triple Negative Breast Cancers, Metastatic Triple Negative Breast Cancers
|
Phase 1/2 |
Recruiting |
2021-03 |
Singapore |
|
NEUROprotection Via optimizINg Cerebral Blood Flow afTer cArdiaC arresT (NEURO-INTACT) Study
|
Not applicable |
Recruiting |
2023-08 |
Singapore |
Pulsed Electromagnetic Fields in Preventing Physical Deconditioning in Patients Undergoing Prolonged Hospitalization
NCT06744764 · ClinicalTrials.gov ↗ · Haematological Cancer, Healthy
|
Not applicable |
Recruiting |
2023-04 |
Singapore |
Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries
NCT07242742 · ClinicalTrials.gov ↗ · Extremely Deep Caries, Pulpitis
|
Not applicable |
Recruiting |
2025-07 |
Singapore |
|
Evaluating Different Protocols of Non-invasive Brain Stimulation (NIBS) in Stroke Rehabilitation
|
Not applicable |
Recruiting |
2024-08 |
Singapore |
Single Centre Prospective Evaluation of 68Gallium-FAPI PET/MRI in Hepatocellular Carcinoma
NCT05687747 · ClinicalTrials.gov ↗ · Hepatocellular Carcinoma
|
Phase 1 |
Recruiting |
2023-08 |
Singapore |
|
Lenvatinib+Letrozole Versus Fulvestrant in Metastatic ER+/HER2- Breast Cancer, Post Progression on Al + CDK4/6 Inhibitor
|
Phase 2 |
Recruiting |
2021-12 |
Singapore |
Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI
NCT05381038 · ClinicalTrials.gov ↗ · Solid Tumor, Gastrointestinal Cancer, Breast Cancer
|
Phase 1/2 |
Recruiting |
2023-02 |
Singapore |
Developing and Testing the Effectiveness of a Skin Cancer Self-Detection Educational Program
NCT07247123 · ClinicalTrials.gov ↗ · Skin Cancer, Skin Cancer Prevention, Benign Skin Growth
|
Not applicable |
Recruiting |
2026-06 |
Singapore |
Neural Network-based Treatment Decision Support Tool in Patients With Refractory Solid Organ Malignancies
NCT05719428 · ClinicalTrials.gov ↗ · Solid Organ Malignancies
|
Phase 2 |
Recruiting |
2023-08 |
Singapore |
tSCS + UL Robotics Training in SCI Patients
NCT07432321 · ClinicalTrials.gov ↗ · Spinal Cord Injuries
|
Not applicable |
Recruiting |
2025-09 |
Singapore |
Multimodal Prehabilitation in Gastric Cancer Patients
NCT07839702 · ClinicalTrials.gov ↗ · Gastric Cancer (GC), Prehabilitation, Postoperative Inflammation
|
Not applicable |
Recruiting |
2026-07 |
Singapore |
Randomised Trial of Induction Gemcitabine and Cisplatin Versus Gemcitabine, Cisplatin, Pembrolizumab and Bevacizumab (GPPB) in Nasopharyngeal Cancer
NCT05305131 · ClinicalTrials.gov ↗ · Nasopharyngeal Cancer
|
Phase 2 |
Recruiting |
2022-03 |
Singapore |
Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer
NCT06846268 · ClinicalTrials.gov ↗ · Locally Advanced Colorectal Cancer
|
Phase 2 |
Recruiting |
2025-04 |
Singapore |
PREcision MApping and NEuromodulation After Spontaneous Intracerebral Hemorrhage: The PREMANE Trial
NCT07908264 · ClinicalTrials.gov ↗ · Spontaneous Intracerebral Hemorrhage
|
Not applicable |
Recruiting |
2026-08 |
Singapore |
Osimertinib for Advanced EGFR-positive NSCLC Patients
NCT05037331 · ClinicalTrials.gov ↗ · EGFR Positive Non-small Cell Lung Cancer, Non Small Cell Lung Cancer
|
Observational |
Recruiting |
2021-07 |
Singapore |
Pembrolizumab and ADG106 in Advanced Solid Cancers and Triple Negative Breast Cancer
NCT05491083 · ClinicalTrials.gov ↗ · Advanced Solid Tumor, Triple Negative Breast Cancer
|
Phase 1/2 |
Recruiting |
2023-06 |
Singapore |
Screening for Early Diagnosis of Nose Cancer
NCT07019870 · ClinicalTrials.gov ↗ · Nasopharyngeal Carcinoma
|
Not applicable |
Recruiting |
2022-11 |
Singapore |
|
Study on the Effect of Atorvastatin Co-administered With Omeprazole on Statin Lactone
|
Phase 4 |
Recruiting |
2025-06 |
Singapore |
Compliance With Standard Care vs Ready to Eat Meals Prior to Bariatric Surgery
NCT06461247 · ClinicalTrials.gov ↗ · Bariatric Surgery Candidate
|
Not applicable |
Recruiting |
2024-07 |
Singapore |
|
Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR Mutations
|
Phase 2 |
Recruiting |
2024-03 |
Singapore |
Ma-Spore ALL 2020 Study
NCT06336395 · ClinicalTrials.gov ↗ · B Lymphoblastic Leukemia
|
Phase 2 |
Recruiting |
2020-03 |
Singapore |
|
Transcutaneous Spinal Cord Stimulation With Robotic Gait Training in Chronic SCI
|
Not applicable |
Recruiting |
2024-11 |
Singapore |
Evaluating the Optimal Timing of Acupuncture for Managing Chemoradiation-induced Xerostomia in Patients With Head and Neck Cancers
NCT07674706 · ClinicalTrials.gov ↗ · Xerostomia, Head Cancer, Neck Cancer
|
Not applicable |
Not yet open |
2026-06 |
Singapore |
Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study
NCT06983795 · ClinicalTrials.gov ↗ · Ischemic Stroke, Patent Foramen Ovale
|
Observational |
Not yet open |
2025-07 |
Singapore |
Tislelizumab in Combination With Bevacizumab and Capecitabine in Advanced Solid Tumors With Evaluation in Immunotherapy-Resistant and Central Nervous System Disease
NCT07681297 · Advanced Solid Tumor Cancer, Triple-Negative Breast Cancer (TNBC), CNS Disease
|
Phase 1/2 |
Not yet open |
2026-08 |
Singapore |
|
Combined rTMS and tSCS for Upper Limb Recovery in Cervical SCI
|
Not applicable |
Not yet open |
2027-03 |
Singapore |
Combined TMS-tSCS for Lower Limb Rehabilitation in Chronic Incomplete SCI
NCT07595497 · ClinicalTrials.gov ↗ · Spinal Cord Injuries (SCI)
|
Not applicable |
Not yet open |
2027-01 |
Singapore |
|
Use of Pyrvinium to Reverse Stomach Precancerous Conditions
|
Phase 2 |
Not yet open |
2026-11 |
Singapore |
Evaluating Ivonescimab in PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma
NCT07565389 · ClinicalTrials.gov ↗ · Nasopharyngeal Carcinoma (NPC)
|
Phase 2 |
Not yet open |
2026-05 |
Singapore |
TTNS in SCI Patients With Neurogenic Detrusor Overactivity
NCT07785258 · ClinicalTrials.gov ↗ · Spinal Cord Injuries, Neurogenic Detrusor Overactivity
|
Not applicable |
Not yet open |
2026-09 |
Singapore |
Early Screening for Gestational Diabetes Mellitus in a Low Risk Population
NCT06704035 · ClinicalTrials.gov ↗ · Gestational Diabetes Mellitus (GDM), Glucose Intolerance During Pregnancy
|
Not applicable |
Not yet open |
2024-12 |
Singapore |
Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure
NCT07460505 · Heart Failure, OSA - Obstructive Sleep Apnea
|
Not applicable |
Not yet open |
2026-05 |
Singapore |
AI-Powered CURAᵀᴹ Application for Identifying At-Risk Pregnancies in Obstetric Management
NCT06974188 · ClinicalTrials.gov ↗ · High-risk Pregnancy, Pregnancy, Antenatal Health
|
Not applicable |
Not yet open |
2025-08 |
Singapore |
Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease
NCT06943482 · ClinicalTrials.gov ↗ · Idiopathic Granulomatous Mastitis
|
Phase 4 |
Not yet open |
2025-07 |
Singapore |
|
Implementation Study on Hospital-to-home Advanced Rehabilitation Technologies (ART)
|
Not applicable |
Not yet open |
2026-11 |
Singapore |
|
Mapping the Neural Circuits of Depression and Anxiety Using Personalized, Accelerated TMS and Deep Phenotyping
|
Not applicable |
Not yet open |
2026-09 |
Singapore |
Study of MC001 in Patients With Advanced Solid Tumours
NCT07929961 · ClinicalTrials.gov ↗ · Pancreatic Ductal Adenocarcinoma (PDAC), Nasopharyngeal Carcinoma, Advanced Solid Tumours
|
Phase 1 |
Not yet open |
2026-11 |
Singapore |
Maintenance Individualized Neuromodulation and Depression-detection Via Sensors for Early Treatment
NCT07779330 · ClinicalTrials.gov ↗ · Depression Disorder
|
Not applicable |
Not yet open |
2026-09 |
Singapore |
Personalized and Accelerated Transcranial Magnetic Stimulation for Treatment-resistant Anxiety Related Disorders
NCT07801391 · ClinicalTrials.gov ↗ · Anxiety and Fear-Related Disorders
|
Not applicable |
Not yet open |
2026-09 |
Singapore |
|
tACS and Upper Limb Rehabilitation in Chronic Stroke
|
Not applicable |
Not yet open |
2026-12 |
Singapore |
|
Lifescapes System in Post-stroke Hand Recovery
|
Not applicable |
Not yet open |
2026-10 |
Singapore |
Community Study to Increase Mammogram Screening Among Overdue Women
NCT07832396 · ClinicalTrials.gov ↗ · This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real World
|
Not applicable |
By invitation |
2026-11 |
Singapore |
Trial to Evaluate the Impact of Various Pragmatic Interventions to Increase Mammography Uptake Among Defaulted Repeat Screeners in Singapore
NCT07651345 · ClinicalTrials.gov ↗ · Mammogram Uptake, Breast Cancer, Breast Neoplasm
|
Not applicable |
By invitation |
2026-03 |
Singapore |
Trial to Evaluate the Impact of Various Behavioural Interventions to Increase Mammography Uptake Among Singaporean Women
NCT07283107 · ClinicalTrials.gov ↗ · This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women
|
Not applicable |
By invitation |
2025-11 |
Singapore |
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
NCT05964933 · ClinicalTrials.gov ↗ · Pulpitis - Irreversible
|
Not applicable |
By invitation |
2023-07 |
Singapore |
Pragmatic Mobile Health Trial to Promote Cancer Screening and Healthy Behaviors
NCT07725328 · ClinicalTrials.gov ↗ · Cancer Screening, Chronic Diseases in Older Adults, Early Cancer Detection
|
Not applicable |
By invitation |
2027-01 |
Singapore |
|
A First-in-Human Study of PRL3-ZUMAB
|
Phase 1 |
Active, closed |
2017-02 |
Singapore |
|
Neoadjuvant Lenvatinib Combined With Letrozole in Hormone Receptor Positive Breast Cancer
|
Phase 1/2 |
Active, closed |
2015-10 |
Singapore |
Bevacizumab and Pembrolizumab Combination in Platinum-resistant Recurrent/Metastatic NPC
NCT03813394 · Locally Recurrent Cancer, Metastatic Nasopharyngeal Cancer
|
Phase 1/2 |
Active, closed |
2019-05 |
Singapore |
|
Validation of a Molecular Test for Risk-stratification of Patients With High-risk Intestinal Metaplasia (GCEP2 Study)
|
Observational |
Active, closed |
2019-08 |
Japan, South Korea, Taiwan, Singapore |
|
To Create an Artificial Intelligence-enabled Device for Airway Assessment (AINFAS) to Identify Patients With Difficult Airway Pre-operatively.
|
Observational |
Active, closed |
2022-05 |
Singapore |
|
Establishing a Prognostic Model for Stroke Recovery
|
Not applicable |
Active, closed |
2020-09 |
Singapore |
Root Canal Treatment With TotalFill® Bioceramic Sealer and AH Plus® Sealer
NCT03732170 · ClinicalTrials.gov ↗ · Root Canal Obturation
|
Not applicable |
Active, closed |
2018-08 |
Singapore |
Conversion Surgery for Gastric Cancer With Peritoneal Metastases (CONVERGENCE)
NCT07241715 · ClinicalTrials.gov ↗ · Gastric Cancer Stage IV, Peritoneal Metastasis
|
Phase 2/3 |
Active, closed |
2026-02 |
Singapore |
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia
NCT07329582 · ClinicalTrials.gov ↗ · Knee Replacement, Total, Knee Replacement Surgery
|
Phase 4 |
Active, closed |
2024-05 |
Singapore |
|
Phase II Study of FTD/TPI (Lonsurf) in Metastatic Breast Cancers With or Without Prior Exposure to Fluoropyrimidines (LONBRECA)
|
Phase 1/2 |
Active, closed |
2019-08 |
Singapore |
A Pilot Study of Ciprofloxacin Plus Gemcitabine and Nab-Paclitaxel Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
NCT04523987 · ClinicalTrials.gov ↗ · Metastatic Pancreatic Ductal Adenocarcinoma
|
Phase 1 |
Active, closed |
2019-02 |
Singapore |
A Phase Ib Safety lead-in, Followed by Phase II Trial of ADG106 in Combination With Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer
NCT05275777 · ClinicalTrials.gov ↗ · HER2-negative Breast Cancer, Advanced Solid Tumor
|
Phase 1/2 |
Active, closed |
2022-05 |
Singapore |
|
Comparison of Pacing Lead Design on Left Bundle Branch Pacing Outcomes: The LEAD_LBBP Randomized Clinical Trial
|
Not applicable |
Active, closed |
2023-01 |
Singapore |
Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study
NCT07210528 · ClinicalTrials.gov ↗ · Mild Cognitive Impairment (MCI), Alzheimer Dementia (AD)
|
Phase 1 |
Active, closed |
2025-06 |
Singapore |
|
A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)
|
Phase 1/2 |
Active, closed |
2020-07 |
Singapore |
Phase I Study of RNA Oligonucleotide, MTL-CEBPA, Atezolizumab and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma.
NCT05097911 · ClinicalTrials.gov ↗ · Advanced Hepatocellular Carcinoma
|
Phase 1 |
Active, closed |
2021-08 |
Singapore |
Growing Up in Singapore Towards Healthy Outcomes
NCT01174875 · ClinicalTrials.gov ↗ · Metabolic Diseases, Neurological and Mental Health Conditions, Genetic Predisposition
|
Observational |
Active, closed |
2009-06 |
Singapore |