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Compound · clinical trials

Dupilumab

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 26 trials in our USA, China, UK, Ireland and India registers that name Dupilumab as an intervention. Synced 24 Sep 2026
26Trials tracked
9Recruiting now
8Lead sponsors
5Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Dupilumab is named as a drug or biological intervention in 26 clinical trials in our USA, China, UK, Ireland and India trial registers, 9 of which are recruiting. Lead sponsors include Sanofi (10), Regeneron Pharmaceuticals (6) and Innovent Biologics (Suzhou) Co. Ltd. (4). Registered phases: Phase 3, Observational, Phase 4, Phase 1 and Phase 2. Conditions studied include Atopic Dermatitis; Asthma; Prurigo Nodularis.

Dupilumab also has an approved-drug profile on this site (FDA label data): Dupixent (Dupilumab) →
01

Clinical trials of Dupilumab

26 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT07053423 A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged โ‰ฅ40 to โ‰ค85 Years With Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease
Phase 4 Recruiting Sanofi UK, USA, China
NCT06293053 A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants โ‰ฅ6 Months to <18 Years of Age With Prurigo Nodularis (ClinicalTrials.gov ↗)
Prurigo Nodularis
Phase 3 Recruiting Sanofi USA
NCT06389136 A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab (ClinicalTrials.gov ↗)
Atopic Dermatitis
Phase 3 Recruiting AbbVie USA
NCT06461897 A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
Atopic Dermatitis
Phase 3 Recruiting AbbVie UK, USA, China
NCT06868212 A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines (ClinicalTrials.gov ↗)
Chronic Spontaneous Urticaria (CSU)
Phase 3 Recruiting Novartis Pharmaceuticals USA
NCT07330934 A Study to Evaluate Efficacy and Safety of IBI356 in Participants With Moderate to Severe Atopic Dermatitis (ClinicalTrials.gov ↗)
Atopic Dermatitis
Phase 2 Recruiting Innovent Biologics (Suzhou) Co. Ltd. China
NCT07399067 A Proof-of-Concept Study of IBI3002 in Patients With Moderate to Severe Atopic Dermatitis (ClinicalTrials.gov ↗)
Atopic Dermatitis
Phase 2 Recruiting Innovent Biologics (Suzhou) Co. Ltd. China
NCT03936335 An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis (AD) (ClinicalTrials.gov ↗)
Adverse Pregnancy Outcomes, Atopic Dermatitis
Observational Recruiting Regeneron Pharmaceuticals USA
NCT07612878 The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry
COPD (Chronic Obstructive Pulmonary Disease)
Observational Recruiting Sanofi USA
NCT07754786 A Study to Evaluate the Equivalence of IBI3027 and Dupilumab Injection in Participants With Moderate to Severe Atopic Dermatitis (ClinicalTrials.gov ↗)
Atopic Dermatitis
Phase 3 Not yet open Innovent Biologics (Suzhou) Co. Ltd. China
NCT07783425 A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema (ClinicalTrials.gov ↗)
Atopic Dermatitis
Phase 3 Not yet open Pfizer USA
NCT07334496 A Study to Evaluate the Biosimilarity of GLR1044 Injection and Dupilumab Injection (Dupixentยฎ) in Healthy Adult Male Subjects (ClinicalTrials.gov ↗)
Biosimilarity
Phase 1 Not yet open Gan & Lee Pharmaceuticals. China
NCT06191315 Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS) (ClinicalTrials.gov ↗)
Wheezing, Asthma
Phase 3 By invitation Sanofi UK, USA
NCT06851403 The Effectiveness and Safety of Dupilumab in Children with Asthma in China: a Real-world Study (ClinicalTrials.gov ↗)
Asthma in Children
Observational By invitation Guangzhou Institute of Respiratory Disease China
NCT05097287 Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma
Asthma
Phase 4 Active, closed Sanofi Ireland, UK, USA, India, China
NCT05983068 A Study of Long-term Effect of Dupilumab on Skin Barrier Function in Pediatric Participants With Atopic Dermatitis
Dermatitis Atopic
Phase 4 Active, closed Sanofi UK, USA
NCT06101095 A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial) (ClinicalTrials.gov ↗)
Eosinophilic Oesophagitis
Phase 4 Active, closed Sanofi USA
NCT06572228 Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma (ClinicalTrials.gov ↗)
Asthma
Phase 4 Active, closed Regeneron Pharmaceuticals USA
NCT02612454 Study to Assess the Long-term Safety of Dupilumab Administered in Participants โ‰ฅ6 Months to <18 Years of Age With Atopic Dermatitis (AD) (ClinicalTrials.gov ↗)
Atopic Dermatitis
Phase 3 Active, closed Regeneron Pharmaceuticals UK, USA
NCT05731128 A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged โ‰ฅ18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab)) (ClinicalTrials.gov ↗)
Colitis Ulcerative
Phase 2 Active, closed Sanofi USA
NCT06369467 Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy
Food Allergy
Phase 1 Active, closed Regeneron Pharmaceuticals USA
NCT07502534 A Clinical Study Comparing the Bioequivalence of IBI3027 and DUPIXENTยฎ(Dupilumab) in Healthy Chinese Volunteers (ClinicalTrials.gov ↗)
Healthy Volunteers
Phase 1 Active, closed Innovent Biologics (Suzhou) Co. Ltd. China
NCT07646548 Pharmacokinetics and Tolerability of Subcutaneous Dupilumab Coformulated With Berahyaluronidase Alfa and Dupilumab Without Berahyaluronidase Alfa in Healthy Participants (ClinicalTrials.gov ↗)
Healthy Volunteers
Phase 1 Active, closed Sanofi USA
NCT03428646 Study of Patients Receiving DUPIXENTยฎ for Atopic Dermatitis (AD) (ClinicalTrials.gov ↗)
Dermatitis, Atopic
Observational Active, closed Regeneron Pharmaceuticals USA
NCT04959448 Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENTยฎ) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) (ClinicalTrials.gov ↗)
Chronic Rhinosinusitis With Nasal Polyposis
Observational Active, closed Regeneron Pharmaceuticals USA
NCT05991323 Real-World Effectiveness of Dupilumab in Patients With Prurigo Nodularis: An Observational Study (ClinicalTrials.gov ↗)
Prurigo Nodularis
Observational Active, closed Sanofi USA, China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

17 conditions
Condition (as registered)Trials
Atopic Dermatitis8
Asthma3
Prurigo Nodularis2
Healthy Volunteers2
Dermatitis Atopic1
Chronic Obstructive Pulmonary Disease1
Wheezing1
COPD (Chronic Obstructive Pulmonary Disease)1
Food Allergy1
Chronic Rhinosinusitis With Nasal Polyposis1
Eosinophilic Oesophagitis1
Chronic Spontaneous Urticaria (CSU)1
Colitis Ulcerative1
Adverse Pregnancy Outcomes1
Dermatitis, Atopic1
Asthma in Children1
Biosimilarity1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Sanofi10
Regeneron Pharmaceuticals6
Innovent Biologics (Suzhou) Co. Ltd.4
AbbVie2
Novartis Pharmaceuticals1
Pfizer1
Guangzhou Institute of Respiratory Disease1
Gan & Lee Pharmaceuticals.1
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Dupilumab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Dupilumab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.