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Compound · clinical trials

Mepolizumab

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our USA, China and UK registers that name Mepolizumab as an intervention. Synced 24 Sep 2026
5Trials tracked
1Recruiting now
4Lead sponsors
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Mepolizumab is named as a drug or biological intervention in 5 clinical trials in our USA, China and UK trial registers, 1 of which is recruiting. Lead sponsors include GlaxoSmithKline (2), AstraZeneca (1) and Eye & ENT Hospital of Fudan University (1). Registered phases: Phase 3, Phase 4 and Phase 2/3. Conditions studied include Eosinophilic Granulomatosis With Polyangiitis; Eosinophilic Granulomatous Vasculitis; Asthma.

Mepolizumab also has an approved-drug profile on this site (FDA label data): Nucala (Mepolizumab) →
01

Clinical trials of Mepolizumab

5 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT05979051 A Study to Evaluate the Efficacy and Safety of SHR-1703 in Subjects With Eosinophilic Granulomatosis With Polyangiitis ๏ผˆEGPA๏ผ‰ (ClinicalTrials.gov ↗)
Eosinophilic Granulomatosis With Polyangiitis
Phase 2/3 Recruiting Guangdong Hengrui Pharmaceutical Co., Ltd China
NCT07200336 Anti-IL-5 Therapy With Simple Polypectomy Versus Extended Endoscopic Sinus Surgery for CRSwNP (ClinicalTrials.gov ↗)
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Phase 4 Not yet open Eye & ENT Hospital of Fudan University China
NCT06041386 REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study (ClinicalTrials.gov ↗)
Asthma
Phase 4 Active, closed GlaxoSmithKline USA
NCT04157348 Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab. (ClinicalTrials.gov ↗)
Eosinophilic Granulomatous Vasculitis
Phase 3 Active, closed AstraZeneca UK, USA
NCT05263934 Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA) (ClinicalTrials.gov ↗)
Eosinophilic Granulomatosis With Polyangiitis
Phase 3 Active, closed GlaxoSmithKline UK, USA, China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

4 conditions
Condition (as registered)Trials
Eosinophilic Granulomatosis With Polyangiitis2
Eosinophilic Granulomatous Vasculitis1
Asthma1
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
GlaxoSmithKline2
AstraZeneca1
Eye & ENT Hospital of Fudan University1
Guangdong Hengrui Pharmaceutical Co., Ltd1
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Mepolizumab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Mepolizumab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.