|
A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia
|
Phase 3 |
Recruiting |
2026-09 |
UK, USA |
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
NCT06585774 · ClinicalTrials.gov ↗ · Chronic Graft-versus-host-disease
|
Phase 3 |
Recruiting |
2025-01 |
Ireland, UK, USA |
|
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
|
Phase 2 |
Recruiting |
2026-05 |
UK, USA |
A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
NCT05836324 · Solid Tumors, Advanced Solid Tumors, Metastatic Solid Tumors
|
Phase 1 |
Recruiting |
2023-07 |
UK, USA, China |
|
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
|
Phase 3 |
Recruiting |
2025-12 |
Ireland, UK, USA |
|
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
|
Phase 2 |
Recruiting |
2026-02 |
USA |
A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Children (6 to < 12 Years Old) With Nonsegmental Vitiligo
NCT06804811 · ClinicalTrials.gov ↗ · NonSegmental Vitiligo
|
Phase 3 |
Recruiting |
2025-11 |
UK |
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
NCT07104565 · ClinicalTrials.gov ↗ · Immune Thrombocytopenia
|
Phase 2 |
Recruiting |
2025-12 |
UK, USA |
|
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
|
Phase 3 |
Recruiting |
2026-04 |
UK, USA |
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
NCT06855498 · ClinicalTrials.gov ↗ · Hidradenitis Suppurativa (HS)
|
Phase 3 |
Recruiting |
2025-02 |
UK, USA |
|
Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease
|
Observational |
Recruiting |
2023-08 |
USA |
|
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
|
Phase 2 |
Recruiting |
2025-11 |
UK, USA |
To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva
NCT05090891 · ClinicalTrials.gov ↗ · Fibrodysplasia Ossificans Progressiva (FOP)
|
Phase 2 |
Recruiting |
2022-05 |
UK, USA, China |
Study of INCA036978 in Participants With Myeloproliferative Neoplasms
NCT07441694 · ClinicalTrials.gov ↗ · Myeloproliferative Neoplasms
|
Phase 1 |
Recruiting |
2026-05 |
UK, USA |
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
NCT07284849 · ClinicalTrials.gov ↗ · CRC (Colorectal Cancer)
|
Phase 3 |
Recruiting |
2026-03 |
UK, USA, China |
A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
NCT06034002 · ClinicalTrials.gov ↗ · Myeloproliferative Neoplasms
|
Phase 1 |
Recruiting |
2023-12 |
USA |
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis
NCT06627335 · ClinicalTrials.gov ↗ · Pregnancy Related, Atopic Dermatitis
|
Observational |
Recruiting |
2023-03 |
USA |
|
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal Disease
|
Phase 1 |
Recruiting |
2026-05 |
USA |
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)
NCT06615050 · ClinicalTrials.gov ↗ · Graft-versus-host Disease (GVHD)
|
Phase 3 |
Recruiting |
2025-04 |
USA |
A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
NCT07195916 · ClinicalTrials.gov ↗ · Solid Tumors, Hematologic Malignancies
|
Phase 1 |
Recruiting |
2026-01 |
USA |
A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo
NCT06548360 · ClinicalTrials.gov ↗ · NonSegmental Vitiligo
|
Phase 3 |
Recruiting |
2025-01 |
USA |
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment
NCT07559474 · ClinicalTrials.gov ↗ · Hepatic Insufficiency, Liver Diseases
|
Phase 1 |
Recruiting |
2026-05 |
USA |
A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants
NCT07588139 · ClinicalTrials.gov ↗ · Healthy Participants
|
Phase 1 |
Recruiting |
2026-05 |
USA |
|
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
|
Phase 1 |
Recruiting |
2024-01 |
USA |
Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population
NCT06259669 · ClinicalTrials.gov ↗ · Pregnancy Related, Atopic Dermatitis
|
Observational |
Recruiting |
2023-09 |
USA |
A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms
NCT07008118 · ClinicalTrials.gov ↗ · Myeloproliferative Neoplasms
|
Phase 1 |
Recruiting |
2025-10 |
USA |
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of INCA033989 Following Subcutaneous or Intravenous Administration in Healthy Adult Participants
NCT07448155 · ClinicalTrials.gov ↗ · Healthy Participants
|
Phase 1 |
Recruiting |
2026-03 |
USA |
Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa
NCT07049575 · ClinicalTrials.gov ↗ · Hidradenitis Suppurativa
|
Phase 1 |
Recruiting |
2025-11 |
USA |
|
Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)
|
Phase 3 |
Active, closed |
2025-06 |
USA |
A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.
NCT04680052 · Follicular Lymphoma, Marginal Zone Lymphoma
|
Phase 3 |
Active, closed |
2021-04 |
Ireland, UK, USA, China |
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients
NCT04824092 · ClinicalTrials.gov ↗ · Diffuse Large B-cell Lymphoma
|
Phase 3 |
Active, closed |
2021-05 |
Ireland, UK, USA |
|
A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
|
Phase 3 |
Active, closed |
2024-01 |
UK, USA |
Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (firmMIND)
NCT05429268 · ClinicalTrials.gov ↗ · Large B-Cell Lymphoma, Diffuse Large B-Cell Lymphoma
|
Phase 3 |
Active, closed |
2022-12 |
Ireland, UK |
A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy
NCT06821542 · ClinicalTrials.gov ↗ · Chronic Graft-versus-host-disease
|
Phase 3 |
Active, closed |
2025-06 |
Ireland, UK |
|
A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms
|
Phase 1 |
Active, closed |
2024-08 |
UK, USA |
A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
NCT05936359 · ClinicalTrials.gov ↗ · Myeloproliferative Neoplasms
|
Phase 1 |
Active, closed |
2023-09 |
UK |
INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders
NCT04455841 · ClinicalTrials.gov ↗ · Anemia, Post-essential Thrombocythemia Myelofibrosis, Post-polycythemia Vera Myelofibrosis
|
Phase 1/2 |
Active, closed |
2021-03 |
UK, USA |
|
A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)
|
Phase 3 |
Active, closed |
2023-11 |
USA |
A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease
NCT06388564 · ClinicalTrials.gov ↗ · Chronic Graft-versus-host-disease
|
Phase 2 |
Active, closed |
2024-10 |
UK, USA |
A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V2)
NCT06113471 · ClinicalTrials.gov ↗ · NonSegmental Vitiligo
|
Phase 3 |
Active, closed |
2023-11 |
UK, USA |
Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465)
NCT04509700 · ClinicalTrials.gov ↗ · B-Cell Malignancies
|
Phase 2 |
Active, closed |
2020-08 |
UK, USA |
|
Study of INCB123667 in Subjects With Advanced Solid Tumors
|
Phase 1 |
Active, closed |
2022-07 |
UK, USA |
Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
NCT04279847 · ClinicalTrials.gov ↗ · Myelofibrosis, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome
|
Phase 1 |
Active, closed |
2021-02 |
UK, USA, China |
|
A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
|
Phase 1 |
Active, closed |
2025-03 |
USA |
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma
NCT05851443 · ClinicalTrials.gov ↗ · Moderate to Severe Asthma
|
Phase 2 |
Active, closed |
2023-07 |
USA |
|
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)
|
Phase 3 |
Active, closed |
2024-10 |
UK, USA |
|
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
|
Phase 3 |
Active, closed |
2025-06 |
UK, USA |
Safety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL Patients
NCT05222555 · ClinicalTrials.gov ↗ · Diffuse Large B Cell Lymphoma
|
Phase 1/2 |
Active, closed |
2022-07 |
USA |
A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive
NCT05879822 · ClinicalTrials.gov ↗ · Advanced Solid Tumor
|
Phase 2 |
Active, closed |
2023-10 |
China |
|
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)
|
Phase 3 |
Active, closed |
2024-10 |
USA |
An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
NCT02955940 · ClinicalTrials.gov ↗ · Pancreatic Cancer, Colorectal Cancer (CRC), Breast Cancer
|
Phase 2 |
Active, closed |
2016-11 |
USA |
Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)
NCT06959225 · ClinicalTrials.gov ↗ · Hidradenitis Suppurativa
|
Phase 3 |
Active, closed |
2025-06 |
USA |
A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD
NCT06843408 · ClinicalTrials.gov ↗ · Chronic Graft-versus-host-disease
|
Phase 1/2 |
Active, closed |
2025-06 |
China |