Clinical Trials in the UK / NCT06212999
Active, not recruiting
Phase 3
A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
NCT06212999 · tracked via the Priya Life Science UK tracker
Condition(s) studied
Hidradenitis Suppurativa (HS)
Study summary
The purpose of this study is to evaluate long-term safety and efficacy of povorcitinib in participants with moderate to severe hidradenitis suppurativa who completed the 54 weeks of study treatment within the originating parent Phase 3 studies (INCB 54707-301 \[NCT05620823\] or INCB 54707-302 \[NCT05620836\]).
Eligibility
Inclusion Criteria:
* Completion of the study treatment period of the originating parent study (INCB 54707-301 or INCB 54707-302).
* Agreement to use contraception.
* Willing and able to comply with the study protocol and procedures.
* Further inclusion criteria apply.
Exclusion Criteria:
* Participation in the extension study could expose the participant to an undue safety risk.
* Women who are pregnant (or who are considering pregnancy) or breastfeeding.
* Further exclusion criteria apply.
Primary outcome measure(s)
- Proportion of participants with Treatment-Emergent Adverse Events (TEAEs) — up to approximately 56 weeks
TEAE is defined as any untoward medical occurrence associated with the use of a drug in humans, whether or not it is considered drug-related. An AE can therefore be any unfavorable or unintended sign (including an abnormal laboratory finding), symptom, or disease (new or exacerbated) temporally associated with the use of study drug.
Trial sites (165)
| Facility | City | Region | Status |
|---|---|---|---|
| Investigative Site US303 | Phoenix | Arizona | |
| Investigative Site US240 | Scottsdale | Arizona | |
| Investigative Site US307 | Fort Smith | Arkansas | |
| Investigative Site US214 | Rogers | Arkansas | |
| Investigative Site US315 | Laguna Niguel | California | |
| Investigative Site US223 | Los Angeles | California | |
| Investigative Site US222 | Oakland | California | |
| Investigative Site US226 | San Diego | California | |
| Investigative Site US309 | Clearwater | Florida | |
| Investigative Site US317 | Hialeah | Florida | |
| Investigative Site US306 | Hollywood | Florida | |
| Investigative Site US320 | Hollywood | Florida | |
| Investigative Site US316 | Maitland | Florida | |
| Investigative Site US227 | Margate | Florida | |
| Investigative Site US204 | Miami | Florida | |
| Investigative Site US236 | Miami | Florida | |
| Investigative Site US321 | North Miami Beach | Florida | |
| Investigative Site US200 | Ocala | Florida | |
| Investigative Site US228 | Tampa | Florida | |
| Investigative Site US201 | Tampa | Florida | |
| Investigative Site US311 | Marietta | Georgia | |
| Investigative Site US220 | West Dundee | Illinois | |
| Investigative Site US206 | Indianapolis | Indiana | |
| Investigative Site US337 | Indianapolis | Indiana | |
| Investigative Site US341 | Bowling Green | Kentucky | |
| Investigative Site US209 | Louisville | Kentucky | |
| Investigative Site US305 | Baton Rouge | Louisiana | |
| Investigative Site US207 | Metairie | Louisiana | |
| Investigative Site US229 | New Orleans | Louisiana | |
| Investigative Site US224 | Baltimore | Maryland | |
| Investigative Site US325 | Marriottsville | Maryland | |
| Investigative Site US225 | Boston | Massachusetts | |
| Investigative Site US304 | Boston | Massachusetts | |
| Investigative Site US310 | Brighton | Massachusetts | |
| Investigative Site US221 | Quincy | Massachusetts | |
| Investigative Site US213 | Fort Gratiot | Michigan | |
| Investigative Site US217 | Waterford | Michigan | |
| Investigative Site US212 | Minneapolis | Minnesota | |
| Investigative Site US302 | St Louis | Missouri | |
| Investigative Site US318 | Portsmouth | New Hampshire |
+ 125 more sites — see the full list on the official registry below.
More Incyte Corporation trials in the UK
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
Active, not recruiting
Other trials for the same condition
A Study With CIT-013 in HS Patients
Active, not recruiting
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06212999 on ClinicalTrials.gov ↗ ← All trials in the UK