๐Ÿ‡ฎ๐Ÿ‡ชIreland
16ยฐC Partly Cloudy ยท Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Priya Life Science Compound trial record
Trackers Drugs Trial finder
Compound · clinical trials

MFOLFIRINOX

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 12 trials in our USA, China and UK registers that name MFOLFIRINOX as an intervention. Synced 24 Sep 2026
12Trials tracked
8Recruiting now
11Lead sponsors
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

MFOLFIRINOX is named as a drug or biological intervention in 12 clinical trials in our USA, China and UK trial registers, 8 of which are recruiting. Lead sponsors include Incyte Corporation (2), Genentech, Inc. (1) and EMD Serono Research & Development Institute, Inc. (1). Registered phases: Phase 1, Phase 2, Phase 1/2 and Phase 2/3. Conditions studied include PDAC - Pancreatic Ductal Adenocarcinoma; Solid Tumors; CRC (Colorectal Cancer).

01

Clinical trials of MFOLFIRINOX

12 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT06079346 A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Ductal Adenocarcinoma
Phase 2/3 Recruiting Oncotelic Inc. USA
NCT06249321 mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer Refractory to Chemotherapy (ClinicalTrials.gov ↗)
Pancreatic Cancer, Radiotherapy
Phase 2 Recruiting Fudan University China
NCT06445062 Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors (ClinicalTrials.gov ↗)
Colorectal Cancer, CRC, Pancreatic Ductal Adenocarcinoma
Phase 1/2 Recruiting Revolution Medicines, Inc. USA
NCT06922591 Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients (ClinicalTrials.gov ↗)
PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC
Phase 1/2 Recruiting Tango Therapeutics, Inc. USA
NCT06179160 A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Solid Tumors
Phase 1 Recruiting Incyte Corporation USA
NCT06835569 A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations (ClinicalTrials.gov ↗)
Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC (Non-small Cell Lung Cancer)
Phase 1 Recruiting Alterome Therapeutics, Inc. USA
NCT06917079 BBO-11818 in Adult Subjects With KRAS Mutant Cancer (ClinicalTrials.gov ↗)
Non-Small Cell Lung Cancer, NSCLC, PDAC - Pancreatic Ductal Adenocarcinoma
Phase 1 Recruiting TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) USA
NCT07166601 M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors
Advanced Solid Tumor
Phase 1 Recruiting EMD Serono Research & Development Institute, Inc. USA
NCT07469956 Surufatinib Plus mFOLFIRINOX and PD-1 Inhibitor as the Neoadjuvant Therapy for High-risk or Borderline Resectable Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer Resectable
Phase 2 Not yet open Sun Yat-sen University China
NCT05968326 A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC (ClinicalTrials.gov ↗)
Adenocarcinoma, Pancreatic Ductal
Phase 2 Active, closed Genentech, Inc. UK, USA
NCT06396091 A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer (ClinicalTrials.gov ↗)
Metastatic Pancreatic Adenocarcinoma
Phase 1 Active, closed Astellas Pharma Global Development, Inc. USA
NCT06818812 A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation (ClinicalTrials.gov ↗)
Solid Tumors
Phase 1 Active, closed Incyte Corporation USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

18 conditions
Condition (as registered)Trials
PDAC - Pancreatic Ductal Adenocarcinoma3
Solid Tumors2
CRC (Colorectal Cancer)2
PDAC2
NSCLC2
Pancreatic Ductal Adenocarcinoma2
Adenocarcinoma, Pancreatic Ductal1
Advanced Solid Tumor1
Cancer1
NSCLC (Non-small Cell Lung Cancer)1
RAS Mutation1
Colorectal Cancer1
CRC1
Non-Small Cell Lung Cancer1
Metastatic Pancreatic Adenocarcinoma1
Pancreatic Cancer1
Radiotherapy1
Pancreatic Cancer Resectable1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Incyte Corporation2
Genentech, Inc.1
EMD Serono Research & Development Institute, Inc.1
Alterome Therapeutics, Inc.1
Tango Therapeutics, Inc.1
Revolution Medicines, Inc.1
Oncotelic Inc.1
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)1
Astellas Pharma Global Development, Inc.1
Fudan University1
Sun Yat-sen University1
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how MFOLFIRINOX works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists MFOLFIRINOX (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.