Calcium folinate is named as an intervention in 12 current clinical trials in our China, USA and UK registers. 7 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Akeso (2). The most-studied condition is Gastroesophageal Adenocarcinoma.
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
1 single-substance product containing Calcium folinate on the HPRA medicines list.
No entry for Calcium folinate in the EMA, FDA or German BfArM shortage lists we track.
| Condition (as registered) | Trials |
|---|---|
| Gastroesophageal Adenocarcinoma | 1 |
| Advanced Solid Tumors | 1 |
| Lymphoma | 1 |
| Metastatic Colorectal Cancer | 1 |
| Colorectal Cancer | 1 |
| Resectable Colon Cancer | 1 |
| MSI-H/dMMR Colorectal Cancer | 1 |
| Gastrointestinal Cancer | 1 |
| Pancreatic Cancer Metastatic to Liver | 1 |
| Intrahepatic Cholangiocarcinoma (Icc) | 1 |
| Hereditary Spastic Paraplegia | 1 |
| Liver Metastases From Colorectal Cancer (mCRC) | 1 |
| Pancreatic Cancer | 1 |
| Lead sponsor | Trials |
|---|---|
| Akeso | 2 |
| Fudan University | 2 |
| AstraZeneca | 1 |
| Bristol-Myers Squibb | 1 |
| Juno Therapeutics, Inc., a Bristol-Myers Squibb Company | 1 |
| Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 1 |
| Zhejiang Doer Biologics Co., Ltd. | 1 |
| Jiang Long | 1 |
| Harbin Medical University | 1 |
| Shanghai 6th People's Hospital | 1 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in China | 10 | 6 |
| Clinical trials in USA | 3 | 2 |
| Clinical trials in UK | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
12 current trials in our China, USA and UK registers name Calcium folinate as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.
Yes. 7 of the 12 trials are recruiting: 6 with sites in China, 2 with sites in USA and 1 with sites in UK. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Akeso (2), Fudan University (2), AstraZeneca (1) and Bristol-Myers Squibb (1), among 10 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Yes. The HPRA medicines list includes 1 single-substance product containing Calcium folinate, for example Folinic acid (as calcium folinate) 10 mg/ml solution for injection/infusion (AS Kalceks). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Not in the lists we track: Calcium folinate has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Calcium folinate works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Calcium folinate works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Calcium folinate (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.