| NCT04516681 |
Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer (ClinicalTrials.gov ↗) Colorectal Cancer, Vitamin C, GLUT3 |
Phase 3 |
Recruiting |
Fudan University |
China |
| NCT06618664 |
A Clinical Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab or Atezolizumab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma (ClinicalTrials.gov ↗) Advanced Hepatocellular Carcinoma |
Phase 3 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT07111832 |
A Clinical Trial of SHR-A1811 in the Treatment of Triple-negative Breast Cancer (ClinicalTrials.gov ↗) PD-L1-positive Locally Recurrent Unresectable or Metastatic Triple-negative Breast Cancer |
Phase 3 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT07679360 |
A Study of Trastuzumab Rezetecan in Combination With Adebrelimab Versus Investigator's Choice of Therapy in Subjects With Residual Triple Negative Breast Cancer (ClinicalTrials.gov ↗) Triple Negative Breast Cancer |
Phase 3 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06791460 |
Pegylated Liposomal Doxorubicin Plus Adebrelimab With or Without Mirabegron in Relapsed Ovarian Cancer (ClinicalTrials.gov ↗) Ovarian Cancer Recurrent |
Phase 2/3 |
Recruiting |
Obstetrics & Gynecology Hospital of Fudan University |
China |
| NCT07454720 |
A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer (ClinicalTrials.gov ↗) Locally Advanced Resectable Rectal Cancer |
Phase 2/3 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT05076682 |
Reverse Triple Negative Immune Resistant Breast Cancer (ClinicalTrials.gov ↗) Triple-negative Breast Cancer |
Phase 2 |
Recruiting |
Fudan University |
China |
| NCT06091124 |
Neoadjuvant Adebrelimab Plus Etoposide and Cisplatin in Neuroendocrine Bladder Carcinoma (ClinicalTrials.gov ↗) Neuroendocrine Carcinoma of the Bladder, Bladder Cancer |
Phase 2 |
Recruiting |
RenJi Hospital |
China |
| NCT06149130 |
Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast Cancer (ClinicalTrials.gov ↗) Breast Cancer |
Phase 2 |
Recruiting |
Tongji Hospital |
China |
| NCT06177925 |
A Phase โ
ก Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC (ClinicalTrials.gov ↗) Respiratory Tract Neoplasms, Thoracic Neoplasms, Neoplasms by Site |
Phase 2 |
Recruiting |
Nanfang Hospital, Southern Medical University |
China |
| NCT06208462 |
Neoadjuvant Therapy of HAIC๏ผGEMOX๏ผ Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors (ClinicalTrials.gov ↗) Intrahepatic Cholangiocarcinoma |
Phase 2 |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
| NCT06261125 |
Combination of SBRT, PD-L1 Inhibitor, and Lenvatinib in Hepatocellular Carcinoma (HSBRT2401) (ClinicalTrials.gov ↗) Hepatocellular Carcinoma |
Phase 2 |
Recruiting |
Mian XI |
China |
| NCT06266832 |
The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma (ClinicalTrials.gov ↗) Rectal Adenocarcinoma |
Phase 2 |
Recruiting |
Sir Run Run Shaw Hospital |
China |
| NCT06277791 |
The Combination of Adebrelimab and TP Regimen for Neoadjuvant Therapy in Patients With Stage IVB Oral Squamous Cell Carcinoma (ClinicalTrials.gov ↗) Clinical IVb Stage Oral Squamous Cell Carcinomas Patients |
Phase 2 |
Recruiting |
Hospital of Stomatology, Wuhan University |
China |
| NCT06282445 |
Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer (ClinicalTrials.gov ↗) Colorectal Cancer Metastatic |
Phase 2 |
Recruiting |
The Fourth Affiliated Hospital of Zhejiang University School of Medicine |
China |
| NCT06340230 |
SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in HR Positive/HER2 Low Breast Cancer (ClinicalTrials.gov ↗) HR Positive/HER2 Low Breast Cancer |
Phase 2 |
Recruiting |
Shengjing Hospital |
China |
| NCT06349889 |
Adebrelimab and Chemoradiotherapy in High-risk LANPC (ClinicalTrials.gov ↗) Nasopharyngeal Carcinoma, Nasopharyngeal Cancer |
Phase 2 |
Recruiting |
Sun Yat-sen University |
China |
| NCT06360042 |
Anti-PD-1/PD-L1 Combined With Anti-angiogenic Agents as First-line Treatment for Unresectable HCC (ClinicalTrials.gov ↗) Unresectable Hepatocellular Carcinoma |
Phase 2 |
Recruiting |
Peking University Cancer Hospital & Institute |
China |
| NCT06415669 |
A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma (ClinicalTrials.gov ↗) Gastric/Gastroesophageal Junction Adenocarcinoma |
Phase 2 |
Recruiting |
The First Affiliated Hospital of Xiamen University |
China |
| NCT06424899 |
A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC (ClinicalTrials.gov ↗) Non Small Cell Lung Cancer |
Phase 2 |
Recruiting |
Zeng Jian |
China |
| NCT06455410 |
GP Plus Adebrelimab Versus GP Neoadjuvant Chemotherapy for Nasopharyngeal Carcinoma (ClinicalTrials.gov ↗) Nasopharyngeal Carcinoma |
Phase 2 |
Recruiting |
Sun Yat-sen University |
China |
| NCT06475209 |
Adebrelimab + Apatinib in SCLC Maintenance Therapy (ClinicalTrials.gov ↗) SCLC |
Phase 2 |
Recruiting |
Tang-Du Hospital |
China |
| NCT06482788 |
Perioperative Treatment of Resectable Adenocarcinoma of Esophagogastric Junction by Immunotherapy (Adebrelimab) Combined With Chemotherapy (XELOX): a Prospective, Single-center, Feasibility Study (ClinicalTrials.gov ↗) Esophagogastric Junction Adenocarcinoma |
Phase 2 |
Recruiting |
Ruijin Hospital |
China |
| NCT06483282 |
A Study of Adebrelimab Combined With Apatinib Mesylate and Chemotherapy for Neoadjuvant Therapy and Biomarker Analysis in Limited-stage Small Cell Lung Cancer (ClinicalTrials.gov ↗) Small Cell Lung Cancer Limited Stage |
Phase 2 |
Recruiting |
Jin Ying |
China |
| NCT06485544 |
Neoadjuvant Adebrelimab in Resectable SCLC: A Randomized Trial (ClinicalTrials.gov ↗) Small Cell Lung Cancer (SCLC) |
Phase 2 |
Recruiting |
Tang-Du Hospital |
China |
| NCT06500208 |
Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC (ClinicalTrials.gov ↗) Breast Cancer |
Phase 2 |
Recruiting |
Shanghai Jiao Tong University School of Medicine |
China |
| NCT06506292 |
A Phase II Trial of Perioperative Adebrelimab Combined With XELOX in Resectable Locally Advanced Gastric/Gastroesophageal Junction Cancer (GC/GEJC) (ClinicalTrials.gov ↗) Adebrelimab (SHR-1316), XELOX, GC/GEJC |
Phase 2 |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
| NCT06510660 |
Adebrelimab ยฑInduction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC (ClinicalTrials.gov ↗) Esophageal Squamous Cell Carcinoma, Immunotherapy, Biomarkers |
Phase 2 |
Recruiting |
Fujian Medical University Union Hospital |
China |
| NCT06531278 |
Adebelimab Combined With Irinotecan Liposomal Injection, Oxaliplatin, Fluorouracil and Calcium Folinate Are Used in the First-line Treatment of Pancreatic Cancer Liver Metastasis Efficacy and Safety (ClinicalTrials.gov ↗) Pancreatic Cancer Metastatic to Liver |
Phase 2 |
Recruiting |
Jiang Long |
China |
| NCT06610734 |
Multicenter, Phase II Randomized Controlled Study of Adebrelimab Combined With Chemotherapy and Concurrent Low-Dose Radiotherapy (LDRT) for the Treatment of Extensive-Stage Small Cell Lung Cancer (SCLC) (ClinicalTrials.gov ↗) Small Cell Lung Cancer Extensive Stage |
Phase 2 |
Recruiting |
Sichuan University |
China |
| NCT06663059 |
Adebrelimab Neoadjuvant Treatment for Resectable ESCC: 2 vs 4 Cycles Study (ClinicalTrials.gov ↗) Esophageal Cancer |
Phase 2 |
Recruiting |
Tang-Du Hospital |
China |
| NCT06749730 |
Adebrelimab Combined with Apatinib and Gemcitabine and Cisplatin (GP) First-line Treatment for Unresectable Biliary Tract Carcinoma (ClinicalTrials.gov ↗) Unresectable Biliary Tract Carcinoma |
Phase 2 |
Recruiting |
Henan Cancer Hospital |
China |
| NCT06765616 |
Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer (ClinicalTrials.gov ↗) Rectal Cancer, Advanced Stage Colorectal Cancer, Radiotherapy |
Phase 2 |
Recruiting |
Feng Tian |
China |
| NCT06895928 |
A Trial of SHR-A2102 With Other Antitumor Therapies in Advanced Solid Tumors (ClinicalTrials.gov ↗) Advanced Solid Tumors |
Phase 2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT07007364 |
Neoadjuvant Low-Dose Radiotherapy Combined With Adebrelimab and Single-Agent Albumin-Bound Paclitaxel Chemotherapy for Early-Stage Oral Squamous Cell Carcinoma: A Prospective, Single-Arm Clinical Trial (ClinicalTrials.gov ↗) Early-Stage Oral Squamous Cell Carcinoma |
Phase 2 |
Recruiting |
Jun Jia |
China |
| NCT07055841 |
Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗) Squamous Cell Carcinoma of Head and Neck |
Phase 2 |
Recruiting |
Xiuping Ding |
China |
| NCT07110571 |
A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer (ClinicalTrials.gov ↗) Gastric Cancer, Gastroesophageal-junction Cancer |
Phase 2 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT07131514 |
HRS-4642 in Combination With Gemcitabine and Albumin-bound Paclitaxel and Adebrelimab for Neoadjuvant and Adjuvant Treatment of Pancreatic Cancer (ClinicalTrials.gov ↗) Pancreatic Cancer |
Phase 2 |
Recruiting |
Ruijin Hospital |
China |
| NCT07135544 |
A Single-arm, Multicenter, Exploratory Study of Adebrelimab Combined With Apatinib and Systemic Chemotherapy for Initially Unresectable Biliary Tract Cancer (ClinicalTrials.gov ↗) Biliary Tract Cancer, Biliary Tract Cancer (CCA) |
Phase 2 |
Recruiting |
Yongjun Chen |
China |
| NCT07141264 |
Adebrelimab Combine With Etoposide Capsules in ES-SCLC Maintenance Therapy (ClinicalTrials.gov ↗) SCLC,Extensive Stage |
Phase 2 |
Recruiting |
Tang-Du Hospital |
China |
| NCT07229729 |
A Study of SHR-A2102 in Combination With Other Anti-tumor Therapies for Resectable Non-small Cell Lung Cancer (ClinicalTrials.gov ↗) Non-small Cell Lung Cancer |
Phase 2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT07241767 |
A Phase II Clinical Study of FH-006 for Injection Combined With Other Anticancer Therapies in Subjects With Lung Cancer (ClinicalTrials.gov ↗) Lung Cancer |
Phase 2 |
Recruiting |
Jiangsu HengRui Medicine Co., Ltd. |
China |
| NCT07241793 |
Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) (ClinicalTrials.gov ↗) Urothelial Carcinoma, Advanced Urothelial Carcinoma, Urothelial Carcinoma Recurrent |
Phase 2 |
Recruiting |
Sun Yat-sen University |
China |
| NCT07268040 |
A Trial of SHR-7787 Injection Combined With Other Anti-tumor Drugs in Patients With Malignant Solid Tumors (ClinicalTrials.gov ↗) Malignant Solid Tumors |
Phase 2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT07437898 |
Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical Study (ClinicalTrials.gov ↗) Esophageal Squamous Cell Carcinoma |
Phase 2 |
Recruiting |
The Affiliated Hospital of Putian University |
China |
| NCT07457346 |
A Study Testing Emactinib Sulfate With Chemotherapy and Immunotherapy Before Surgery for Advanced Head and Neck Cancer (ClinicalTrials.gov ↗) Head and Neck Cancer Squamous Cell Carcinoma |
Phase 2 |
Recruiting |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
China |
| NCT07569679 |
Alternating HAIC and Systemic Chemotherapy With or Without Adebrelimab and Apatinib for Unresectable Biliary Tract Cancer (ClinicalTrials.gov ↗) Biliary Tract Cancer |
Phase 2 |
Recruiting |
Air Force Military Medical University, China |
China |
| NCT07638852 |
Study of Radiotherapy Combined With Cisplatin/Carboplatin, Adebrelimab and Bevacizumab in the Treatment of TNBC-BM. (ClinicalTrials.gov ↗) TNBC, Triple Negative Breast Cancer, Brain Metastasases |
Phase 2 |
Recruiting |
Fudan University |
China |
| NCT07668453 |
An Open-label, Single-arm, Multicenter Exploratory Study of Adebrelimab Combined With Gemcitabine and Albumin-bound Paclitaxel as First-line Treatment for Biliary Tract Malignancies (ClinicalTrials.gov ↗) Biliary Tract Neoplasms |
Phase 2 |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
| NCT07670273 |
Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer (ClinicalTrials.gov ↗) Biliary Tract Neoplasms Immunotherapy |
Phase 2 |
Recruiting |
Peking Union Medical College Hospital |
China |
| NCT07704177 |
Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib in Advanced HER2-Positive/Low-Expression Biliary Tract Cancer (ClinicalTrials.gov ↗) Biliary Tract Neoplasms Immunotherapy |
Phase 2 |
Recruiting |
Peking Union Medical College Hospital |
China |
| NCT07718490 |
Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer (ClinicalTrials.gov ↗) Metastatic Colorectal Cancer |
Phase 2 |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
| NCT07731828 |
Neoadjuvant Short-course Hypofractionated Radiotherapy Plus Adebrelimab and Platinum Chemotherapy in Locally Advanced Cervical Cancer: A Single-arm Phase II Trial (ClinicalTrials.gov ↗) Cervical Neoplasms |
Phase 2 |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
| NCT07733830 |
Comparing ICI Followed By CCRT And CCRT Followed By Immunotherapy In Unresectable LA-ESCC (ClinicalTrials.gov ↗) Esophageal Cancer |
Phase 2 |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
| NCT07770113 |
A Random, Non-controlled, Open Clinical Study of Apatinib Mesylate Combined With Albumin-bound Paclitaxel ยฑ Adebrelimab in Treating Advanced Second-line Gastric Cancer (ClinicalTrials.gov ↗) GC/GEJC |
Phase 2 |
Recruiting |
The First Affiliated Hospital of Zhengzhou University |
China |
| NCT06222879 |
Study of HRS-8080 or SHR-A2009 Combined With Anti-tumor Therapy in Patients With Unresectable or Metastatic Breast Cancer (ClinicalTrials.gov ↗) Breast Cancer |
Phase 1/2 |
Recruiting |
Shandong Suncadia Medicine Co., Ltd. |
China |
| NCT06427239 |
Exploratory Clinical Study of HRS-4642 Combined With Adebrelimab in the Treatment of Advanced Pancreatic Ductal Adenocarcinoma (ClinicalTrials.gov ↗) Pancreatic Cancer |
Phase 1/2 |
Recruiting |
Fudan University |
China |
| NCT06474455 |
A Phase IB/II Clinical Study of SHR-9839 for Injection Combined With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors (ClinicalTrials.gov ↗) Advanced Solid Tumors |
Phase 1/2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT06512051 |
A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer (ClinicalTrials.gov ↗) Advanced or Metastatic Non-small Cell Lung Cancer |
Phase 1/2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT06589778 |
A Study of SHR-A2102 in Combination With Adebrelimab and SHR-8068 in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (ClinicalTrials.gov ↗) Non-Small Cell Lung Cancer |
Phase 1/2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT06639347 |
A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma (ClinicalTrials.gov ↗) Advanced Urothelial Carcinoma |
Phase 1/2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT06754930 |
A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With NSCLC (ClinicalTrials.gov ↗) Non-small Cell Lung Cancer (NSCLC) |
Phase 1/2 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06776770 |
A Phase Ib/II Study of Adebrelimab in Combination with Capecitabine and Oxaliplatin in Cancer (ClinicalTrials.gov ↗) Gastric Cancer |
Phase 1/2 |
Recruiting |
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center |
China |
| NCT06840002 |
A Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer (ClinicalTrials.gov ↗) Ovarian Cancer |
Phase 1/2 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06859775 |
SHR-A1811 Combination Regimen for the Treatment of Recurrent or Metastatic Cervical Cancer (ClinicalTrials.gov ↗) Recurrent or Metastatic Cervical Cancer |
Phase 1/2 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT07059221 |
A Trial of SHR-A2102 With Adebrelimab With or Without Other Anti-tumor Therapies in Recurrent/MetastaticHead and Neck Squamous Cell Carcinoma Cancer (ClinicalTrials.gov ↗) Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma |
Phase 1/2 |
Recruiting |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT07105592 |
A Study of Nimotuzumab Plus Adebrelimab With Chemotherapy in Cisplatin-Ineligible Patients With Head And Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗) Head and Neck Squamous Cell Carcinoma |
Phase 1/2 |
Recruiting |
Fudan University |
China |
| NCT07229586 |
A Study of SHR-7367 With Anti-tumor Agents in Patients With Solid Tumors (ClinicalTrials.gov ↗) Solid Tumor |
Phase 1/2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT07296341 |
HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors (ClinicalTrials.gov ↗) Locally Advanced or Metastatic Pancreatic Cancer With |
Phase 1/2 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT07595172 |
NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic Cancer (ClinicalTrials.gov ↗) Pancreatic Ductal Adenocarcinoma (PDAC), Locally Advanced and Metastatic Pancreatic Cancer |
Phase 1/2 |
Recruiting |
West China Hospital |
China |
| NCT06181032 |
A Study of Adebrelimab in Combination With Apatinib Gemcitabine and Cisplatin in Biliary Tract Malignancies (ClinicalTrials.gov ↗) Biliary Tract Malignancies |
Phase 1 |
Recruiting |
First Affiliated Hospital of Fujian Medical University |
China |
| NCT06332170 |
ARTEMIS-101: A Study of HS-20093 Combinations in Patients With Advanced Solid Tumors (ClinicalTrials.gov ↗) Advanced Solid Tumor |
Phase 1 |
Recruiting |
Hansoh BioMedical R&D Company |
China |
| NCT06336707 |
HS-20089 Combination Treatment in Subjects With Advanced Solid Tumors (ClinicalTrials.gov ↗) Advanced Solid Tumors |
Phase 1 |
Recruiting |
Hansoh BioMedical R&D Company |
China |
| NCT06350006 |
SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor (ClinicalTrials.gov ↗) CLDN18.2-positive Advanced Solid Tumor |
Phase 1 |
Recruiting |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT07434518 |
A Real-World Study Evaluating the Efficacy and Safety of Adebrelimab in Patients With Advanced SCLC (ClinicalTrials.gov ↗) Small Cell Lung Cancer (SCLC) |
Observational |
Recruiting |
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine |
China |
| NCT07640048 |
Adjuvant Therapy for High-Risk Intrahepatic Cholangiocarcinoma: A Real-World Study (ClinicalTrials.gov ↗) Intrahepatic Cholangiocarcinoma (Icc) |
Observational |
Recruiting |
Peking Union Medical College Hospital |
China |
| NCT06853678 |
Second-line Immunotherapy for ES-SCLC (ClinicalTrials.gov ↗) Extensive Stage Small Cell Lung Cancer (ES-SCLC) |
Not applicable |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
| NCT06156267 |
Study of Personalized Tumour Vaccines and a PD-L1 Blocker in Patients With Surgically Resected Pancreatic Adenocarcino (ClinicalTrials.gov ↗) Pancreatic Cancer |
Phase EARLY_PHASE1 |
Not yet open |
Fudan University |
China |
| NCT07691762 |
A Study of TACE in Combination With SHR-8068, Adebrelimab, and Bevacizumab Versus TACE in Participants With Incurable Hepatocellular Carcinoma (ClinicalTrials.gov ↗) Hepatocellular Carcinoma |
Phase 3 |
Not yet open |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06177522 |
Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer (ClinicalTrials.gov ↗) Pancreatic Cancer, Neoadjuvant Therapy |
Phase 2 |
Not yet open |
Jinling Hospital, China |
China |
| NCT06236997 |
Adebrelimab and Concurrent Radiochemotherapy as First-line Treatment for Extensive-stage Small-cell Lung Cancer (ClinicalTrials.gov ↗) Small Cell Lung Carcinoma |
Phase 2 |
Not yet open |
Henan Cancer Hospital |
China |
| NCT06592625 |
Neoadjuvant SHR-A1811 Plus Adebrelimab in HR Negative/Low & HER2 Low Breast Cancer Patients (ClinicalTrials.gov ↗) Untreated Early-stage or Locally Advanced Breast Cancer |
Phase 2 |
Not yet open |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06648525 |
Adebrelimab Combined with Irinotecan Liposomes, 5-FU, CF ยฑ Lenvatinib As First-line Treatment for Advanced ICC (ClinicalTrials.gov ↗) Intrahepatic Cholangiocarcinoma (Icc) |
Phase 2 |
Not yet open |
Harbin Medical University |
China |
| NCT06684158 |
Mecapegfilgrastim Combined With Adebrelimab and Chemotherapy as Neoadjuvant Therapy in Resectable GC/GEJC (ClinicalTrials.gov ↗) GC/GEJC |
Phase 2 |
Not yet open |
The First Affiliated Hospital with Nanjing Medical University |
China |
| NCT06786312 |
A Single-arm, Multicenter, Prospective Phase II Clinical Study of Apatinib in Combination With Adebrelimab and EC Regimen in the First-line Treatment of Extensive Small Cell Lung Cancer (ClinicalTrials.gov ↗) Small Cell Lung Cancer Extensive Stage |
Phase 2 |
Not yet open |
Fujian Cancer Hospital |
China |
| NCT07031154 |
A Single-arm, Multicenter, Prospective Clinical Study of Adebrelimab Combined With Apatinib Neoadjuvant Therapy for Resectable Non-small Cell Lung Cancer (ClinicalTrials.gov ↗) Non-Small Cell Lung Cancer, Adebrelimab, Apatinib |
Phase 2 |
Not yet open |
The First Affiliated Hospital of Xiamen University |
China |
| NCT07041437 |
Study of SHR-A2102 Combined Other Antitumor Drugs in Advanced Breast Cancer (ClinicalTrials.gov ↗) Advanced Breast Cancer |
Phase 2 |
Not yet open |
Fudan University |
China |
| NCT07317778 |
Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast Cancer (ClinicalTrials.gov ↗) Breast Cancer Early Stage Breast Cancer (Stage 1-3), HR Positive/HER2 Low Breast Cancer |
Phase 2 |
Not yet open |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
China |
| NCT07357532 |
Exploration of Treatment Strategies After Concurrent Chemoradiotherapy for LS-SCLC Guided by MRD (ClinicalTrials.gov ↗) Small Cell Lung Carcinoma |
Phase 2 |
Not yet open |
Peking University Cancer Hospital & Institute |
China |
| NCT07398560 |
Adebrelimab Combined With Oral Etoposide for Elderly Patients and Patients With Poor Performance Status in Small Cell Lung Cancer: An Exploratory Clinical Study (ClinicalTrials.gov ↗) Small Cell Lung Cancer |
Phase 2 |
Not yet open |
The Third Affiliated Hospital of Harbin Medical University |
China |
| NCT07466927 |
Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases (ClinicalTrials.gov ↗) HER2-negative Breast Cancer |
Phase 2 |
Not yet open |
Fudan University |
China |
| NCT07554768 |
Neoadjuvant Radio-immunotherapy Versus Immunotherapy Alone for Locally Advanced HNSCC (ClinicalTrials.gov ↗) Head and Neck Squamous Cell Carcinoma, Locally Advanced Head and Neck Squamous Cell Carcinoma |
Phase 2 |
Not yet open |
Chen Chunyan |
China |
| NCT07684040 |
A Study of Combination Therapy in Patients With Resectable Liver Cancer (ClinicalTrials.gov ↗) Liver Cancer (Primary and Metastatic) |
Phase 2 |
Not yet open |
Affiliated Hospital of Guangdong Medical University |
China |
| NCT07704645 |
The Clinical Study of Adalimumab Combined With Other Anti-tumor Therapy as a Treatment for Resectable Non-small Cell Lung Cancer (ClinicalTrials.gov ↗) Resectable Non-small Cell Lung Cancer |
Phase 2 |
Not yet open |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT07770672 |
An Exploratory Clinical Study of Accurate Efficacy Assessment of Neoadjuvant Immunotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma Based on 68Ga-FAPI ([68Ga] Fibroblast Activation Protein Inhibitor)/ยนโธF-FDG (2-Deoxy-2-[ยนโธF]Fluoro-D-glucose) Dual Imaging (ClinicalTrials.gov ↗) Esophageal Cancer, ESCC |
Phase 2 |
Not yet open |
Tan Lijie |
China |
| NCT07780721 |
Study of Adebrelimab Combined With Thymalfasin and Chemotherapy for Neoadjuvant Treatment of Esophageal Cancer (ClinicalTrials.gov ↗) Esophageal Cancer |
Phase 2 |
Not yet open |
The Affiliated Hospital of Putian University |
China |
| NCT07798947 |
A Phase II Clinical Study of SHR-7787 Injection Combined With SHR-1316 Injection in Patients With LS-SCLC (ClinicalTrials.gov ↗) Limited-stage Small-cell Lung Cancer |
Phase 2 |
Not yet open |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
China |
| NCT07811375 |
Perioperative Adebrelimab for Locally Advanced Cervical Cancer (ClinicalTrials.gov ↗) Locally Advanced Cervical Cancer |
Phase 2 |
Not yet open |
Anhui Provincial Hospital |
China |
| NCT07736612 |
A Pan-RAS Inhibitor in Combination With Anti-Tumor Therapy in Participants With Advanced Pancreatic Cancer (ClinicalTrials.gov ↗) Pancreatic Cancer, RAS Mutations or Amplifications |
Phase 1/2 |
Not yet open |
Zhejiang University |
China |
| NCT07806058 |
An Open-Label, Multicenter, Phase IB/II Clinical Study of HRS-7172 in Combination With Antitumor Therapy in Participants With Solid Tumors (ClinicalTrials.gov ↗) Pancreatic Cancer |
Phase 1/2 |
Not yet open |
Jiangsu HengRui Medicine Co., Ltd. |
China |
| NCT06963502 |
A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Patients With Advanced Solid Tumors (ClinicalTrials.gov ↗) Advanced Solid Tumors, Colorectal Cancer, Non-Small Cell Lung Cancer |
Phase 1 |
Not yet open |
Jiangsu Hansoh Pharmaceutical Co., Ltd. |
China |
| NCT06773156 |
Adjuvant Adebrelimab Plus Apatinib After Chemoradiation in Limited-Stage Small Cell Lung Cancer (ClinicalTrials.gov ↗) Limited-stage Small Cell Lung Cancer (LS-SCLC) |
Phase 2 |
By invitation |
Second Affiliated Hospital of Nanchang University |
China |
| NCT06247956 |
Study of SHR-8068 Combined With Adebrelimab and Platinum-containing Chemotherapy in the Treatment of Advanced Gastric and Esophageal Cancer (ClinicalTrials.gov ↗) Advanced Gastric Adenocarcinoma and Esophageal Squamous Cell Carcinoma |
Phase 2 |
Active, closed |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06465563 |
SHR-8068 in Combination With Adebrelimab, Bevacizumab, and Platinum-Based Chemotherapy as First-line Treatment in Patients With Advanced Biliary Tract Cancer (ClinicalTrials.gov ↗) Biliary Tract Cancer |
Phase 2 |
Active, closed |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06599216 |
Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR + / HER2- Breast Cancer (ClinicalTrials.gov ↗) Breast Cancer, HR+/HER2- Breast Cancer |
Phase 2 |
Active, closed |
Harbin Medical University |
China |
| NCT06700421 |
Phase II Clinical Study of Adebrelimab Combined with Apatinib in the Treatment of Locally Advanced Non-small Cell Lung Cancer Patients with Radiation Pneumonitis (ClinicalTrials.gov ↗) Unresectable Locally Advanced Non-small Cell Lung Cancer |
Phase 2 |
Active, closed |
Wei Zhou |
China |
| NCT06766019 |
Adebrelimab Combined With Irinotecan Liposomal (II), Oxaliplatin, and 5-FU/LV Conversion Therapy for Locally Advanced Pancreatic Cancer (ClinicalTrials.gov ↗) Pancreatic Cancer |
Phase 2 |
Active, closed |
The First Affiliated Hospital with Nanjing Medical University |
China |
| NCT07071714 |
A Phase II Study of SHR-8068 Injection in Combination With Anti-tumor Therapies in Colorectal Cancer (ClinicalTrials.gov ↗) Colorectal Cancer |
Phase 2 |
Active, closed |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |
| NCT06385678 |
A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation (ClinicalTrials.gov ↗) Advanced KRAS G12D Mutant Solid Tumors |
Phase 1/2 |
Active, closed |
Jiangsu HengRui Medicine Co., Ltd. |
China |
| NCT07009457 |
A Clinical Study of SHR-1316 (SC) Combined With Carboplatin and Etoposide as First-line Treatment for Extensive Stage Small Cell Lung Cancer (ClinicalTrials.gov ↗) Widespread Small Cell Lung Cancer |
Phase 1 |
Active, closed |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
China |