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Compound · clinical trials

Adebrelimab

Also listed in trial records as SHR-1316, Adebelimab, HTI-1088, SHR-A1316
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 110 trials in our China register that name Adebrelimab as an intervention. Synced 25 Sep 2026
110Trials tracked
77Recruiting now
55Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Adebrelimab is named as a drug or biological intervention in 110 clinical trials in our China trial register, 77 of which are recruiting. Lead sponsors include Suzhou Suncadia Biopharmaceuticals Co., Ltd. (16), Shanghai Hengrui Pharmaceutical Co., Ltd. (11) and Fudan University (8). Registered phases: Phase 2, Phase 1/2, Phase 1, Phase 3, Observational, Phase 2/3, Not applicable and Phase EARLY_PHASE1. Conditions studied include Pancreatic Cancer; Esophageal Cancer; Breast Cancer.

01

Clinical trials of Adebrelimab

110 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT04516681 Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer (ClinicalTrials.gov ↗)
Colorectal Cancer, Vitamin C, GLUT3
Phase 3 Recruiting Fudan University China
NCT06618664 A Clinical Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab or Atezolizumab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma (ClinicalTrials.gov ↗)
Advanced Hepatocellular Carcinoma
Phase 3 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT07111832 A Clinical Trial of SHR-A1811 in the Treatment of Triple-negative Breast Cancer (ClinicalTrials.gov ↗)
PD-L1-positive Locally Recurrent Unresectable or Metastatic Triple-negative Breast Cancer
Phase 3 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT07679360 A Study of Trastuzumab Rezetecan in Combination With Adebrelimab Versus Investigator's Choice of Therapy in Subjects With Residual Triple Negative Breast Cancer (ClinicalTrials.gov ↗)
Triple Negative Breast Cancer
Phase 3 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06791460 Pegylated Liposomal Doxorubicin Plus Adebrelimab With or Without Mirabegron in Relapsed Ovarian Cancer (ClinicalTrials.gov ↗)
Ovarian Cancer Recurrent
Phase 2/3 Recruiting Obstetrics & Gynecology Hospital of Fudan University China
NCT07454720 A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer (ClinicalTrials.gov ↗)
Locally Advanced Resectable Rectal Cancer
Phase 2/3 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT05076682 Reverse Triple Negative Immune Resistant Breast Cancer (ClinicalTrials.gov ↗)
Triple-negative Breast Cancer
Phase 2 Recruiting Fudan University China
NCT06091124 Neoadjuvant Adebrelimab Plus Etoposide and Cisplatin in Neuroendocrine Bladder Carcinoma (ClinicalTrials.gov ↗)
Neuroendocrine Carcinoma of the Bladder, Bladder Cancer
Phase 2 Recruiting RenJi Hospital China
NCT06149130 Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast Cancer (ClinicalTrials.gov ↗)
Breast Cancer
Phase 2 Recruiting Tongji Hospital China
NCT06177925 A Phase โ…ก Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC (ClinicalTrials.gov ↗)
Respiratory Tract Neoplasms, Thoracic Neoplasms, Neoplasms by Site
Phase 2 Recruiting Nanfang Hospital, Southern Medical University China
NCT06208462 Neoadjuvant Therapy of HAIC๏ผˆGEMOX๏ผ‰ Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors (ClinicalTrials.gov ↗)
Intrahepatic Cholangiocarcinoma
Phase 2 Recruiting The First Affiliated Hospital with Nanjing Medical University China
NCT06261125 Combination of SBRT, PD-L1 Inhibitor, and Lenvatinib in Hepatocellular Carcinoma (HSBRT2401) (ClinicalTrials.gov ↗)
Hepatocellular Carcinoma
Phase 2 Recruiting Mian XI China
NCT06266832 The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma (ClinicalTrials.gov ↗)
Rectal Adenocarcinoma
Phase 2 Recruiting Sir Run Run Shaw Hospital China
NCT06277791 The Combination of Adebrelimab and TP Regimen for Neoadjuvant Therapy in Patients With Stage IVB Oral Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Clinical IVb Stage Oral Squamous Cell Carcinomas Patients
Phase 2 Recruiting Hospital of Stomatology, Wuhan University China
NCT06282445 Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer (ClinicalTrials.gov ↗)
Colorectal Cancer Metastatic
Phase 2 Recruiting The Fourth Affiliated Hospital of Zhejiang University School of Medicine China
NCT06340230 SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in HR Positive/HER2 Low Breast Cancer (ClinicalTrials.gov ↗)
HR Positive/HER2 Low Breast Cancer
Phase 2 Recruiting Shengjing Hospital China
NCT06349889 Adebrelimab and Chemoradiotherapy in High-risk LANPC (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma, Nasopharyngeal Cancer
Phase 2 Recruiting Sun Yat-sen University China
NCT06360042 Anti-PD-1/PD-L1 Combined With Anti-angiogenic Agents as First-line Treatment for Unresectable HCC (ClinicalTrials.gov ↗)
Unresectable Hepatocellular Carcinoma
Phase 2 Recruiting Peking University Cancer Hospital & Institute China
NCT06415669 A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma (ClinicalTrials.gov ↗)
Gastric/Gastroesophageal Junction Adenocarcinoma
Phase 2 Recruiting The First Affiliated Hospital of Xiamen University China
NCT06424899 A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC (ClinicalTrials.gov ↗)
Non Small Cell Lung Cancer
Phase 2 Recruiting Zeng Jian China
NCT06455410 GP Plus Adebrelimab Versus GP Neoadjuvant Chemotherapy for Nasopharyngeal Carcinoma (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma
Phase 2 Recruiting Sun Yat-sen University China
NCT06475209 Adebrelimab + Apatinib in SCLC Maintenance Therapy (ClinicalTrials.gov ↗)
SCLC
Phase 2 Recruiting Tang-Du Hospital China
NCT06482788 Perioperative Treatment of Resectable Adenocarcinoma of Esophagogastric Junction by Immunotherapy (Adebrelimab) Combined With Chemotherapy (XELOX): a Prospective, Single-center, Feasibility Study (ClinicalTrials.gov ↗)
Esophagogastric Junction Adenocarcinoma
Phase 2 Recruiting Ruijin Hospital China
NCT06483282 A Study of Adebrelimab Combined With Apatinib Mesylate and Chemotherapy for Neoadjuvant Therapy and Biomarker Analysis in Limited-stage Small Cell Lung Cancer (ClinicalTrials.gov ↗)
Small Cell Lung Cancer Limited Stage
Phase 2 Recruiting Jin Ying China
NCT06485544 Neoadjuvant Adebrelimab in Resectable SCLC: A Randomized Trial (ClinicalTrials.gov ↗)
Small Cell Lung Cancer (SCLC)
Phase 2 Recruiting Tang-Du Hospital China
NCT06500208 Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC (ClinicalTrials.gov ↗)
Breast Cancer
Phase 2 Recruiting Shanghai Jiao Tong University School of Medicine China
NCT06506292 A Phase II Trial of Perioperative Adebrelimab Combined With XELOX in Resectable Locally Advanced Gastric/Gastroesophageal Junction Cancer (GC/GEJC) (ClinicalTrials.gov ↗)
Adebrelimab (SHR-1316), XELOX, GC/GEJC
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
NCT06510660 Adebrelimab ยฑInduction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC (ClinicalTrials.gov ↗)
Esophageal Squamous Cell Carcinoma, Immunotherapy, Biomarkers
Phase 2 Recruiting Fujian Medical University Union Hospital China
NCT06531278 Adebelimab Combined With Irinotecan Liposomal Injection, Oxaliplatin, Fluorouracil and Calcium Folinate Are Used in the First-line Treatment of Pancreatic Cancer Liver Metastasis Efficacy and Safety (ClinicalTrials.gov ↗)
Pancreatic Cancer Metastatic to Liver
Phase 2 Recruiting Jiang Long China
NCT06610734 Multicenter, Phase II Randomized Controlled Study of Adebrelimab Combined With Chemotherapy and Concurrent Low-Dose Radiotherapy (LDRT) for the Treatment of Extensive-Stage Small Cell Lung Cancer (SCLC) (ClinicalTrials.gov ↗)
Small Cell Lung Cancer Extensive Stage
Phase 2 Recruiting Sichuan University China
NCT06663059 Adebrelimab Neoadjuvant Treatment for Resectable ESCC: 2 vs 4 Cycles Study (ClinicalTrials.gov ↗)
Esophageal Cancer
Phase 2 Recruiting Tang-Du Hospital China
NCT06749730 Adebrelimab Combined with Apatinib and Gemcitabine and Cisplatin (GP) First-line Treatment for Unresectable Biliary Tract Carcinoma (ClinicalTrials.gov ↗)
Unresectable Biliary Tract Carcinoma
Phase 2 Recruiting Henan Cancer Hospital China
NCT06765616 Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer (ClinicalTrials.gov ↗)
Rectal Cancer, Advanced Stage Colorectal Cancer, Radiotherapy
Phase 2 Recruiting Feng Tian China
NCT06895928 A Trial of SHR-A2102 With Other Antitumor Therapies in Advanced Solid Tumors (ClinicalTrials.gov ↗)
Advanced Solid Tumors
Phase 2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT07007364 Neoadjuvant Low-Dose Radiotherapy Combined With Adebrelimab and Single-Agent Albumin-Bound Paclitaxel Chemotherapy for Early-Stage Oral Squamous Cell Carcinoma: A Prospective, Single-Arm Clinical Trial (ClinicalTrials.gov ↗)
Early-Stage Oral Squamous Cell Carcinoma
Phase 2 Recruiting Jun Jia China
NCT07055841 Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Squamous Cell Carcinoma of Head and Neck
Phase 2 Recruiting Xiuping Ding China
NCT07110571 A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer (ClinicalTrials.gov ↗)
Gastric Cancer, Gastroesophageal-junction Cancer
Phase 2 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT07131514 HRS-4642 in Combination With Gemcitabine and Albumin-bound Paclitaxel and Adebrelimab for Neoadjuvant and Adjuvant Treatment of Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer
Phase 2 Recruiting Ruijin Hospital China
NCT07135544 A Single-arm, Multicenter, Exploratory Study of Adebrelimab Combined With Apatinib and Systemic Chemotherapy for Initially Unresectable Biliary Tract Cancer (ClinicalTrials.gov ↗)
Biliary Tract Cancer, Biliary Tract Cancer (CCA)
Phase 2 Recruiting Yongjun Chen China
NCT07141264 Adebrelimab Combine With Etoposide Capsules in ES-SCLC Maintenance Therapy (ClinicalTrials.gov ↗)
SCLC,Extensive Stage
Phase 2 Recruiting Tang-Du Hospital China
NCT07229729 A Study of SHR-A2102 in Combination With Other Anti-tumor Therapies for Resectable Non-small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-small Cell Lung Cancer
Phase 2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT07241767 A Phase II Clinical Study of FH-006 for Injection Combined With Other Anticancer Therapies in Subjects With Lung Cancer (ClinicalTrials.gov ↗)
Lung Cancer
Phase 2 Recruiting Jiangsu HengRui Medicine Co., Ltd. China
NCT07241793 Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) (ClinicalTrials.gov ↗)
Urothelial Carcinoma, Advanced Urothelial Carcinoma, Urothelial Carcinoma Recurrent
Phase 2 Recruiting Sun Yat-sen University China
NCT07268040 A Trial of SHR-7787 Injection Combined With Other Anti-tumor Drugs in Patients With Malignant Solid Tumors (ClinicalTrials.gov ↗)
Malignant Solid Tumors
Phase 2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT07437898 Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical Study (ClinicalTrials.gov ↗)
Esophageal Squamous Cell Carcinoma
Phase 2 Recruiting The Affiliated Hospital of Putian University China
NCT07457346 A Study Testing Emactinib Sulfate With Chemotherapy and Immunotherapy Before Surgery for Advanced Head and Neck Cancer (ClinicalTrials.gov ↗)
Head and Neck Cancer Squamous Cell Carcinoma
Phase 2 Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine China
NCT07569679 Alternating HAIC and Systemic Chemotherapy With or Without Adebrelimab and Apatinib for Unresectable Biliary Tract Cancer (ClinicalTrials.gov ↗)
Biliary Tract Cancer
Phase 2 Recruiting Air Force Military Medical University, China China
NCT07638852 Study of Radiotherapy Combined With Cisplatin/Carboplatin, Adebrelimab and Bevacizumab in the Treatment of TNBC-BM. (ClinicalTrials.gov ↗)
TNBC, Triple Negative Breast Cancer, Brain Metastasases
Phase 2 Recruiting Fudan University China
NCT07668453 An Open-label, Single-arm, Multicenter Exploratory Study of Adebrelimab Combined With Gemcitabine and Albumin-bound Paclitaxel as First-line Treatment for Biliary Tract Malignancies (ClinicalTrials.gov ↗)
Biliary Tract Neoplasms
Phase 2 Recruiting The First Affiliated Hospital with Nanjing Medical University China
NCT07670273 Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer (ClinicalTrials.gov ↗)
Biliary Tract Neoplasms Immunotherapy
Phase 2 Recruiting Peking Union Medical College Hospital China
NCT07704177 Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib in Advanced HER2-Positive/Low-Expression Biliary Tract Cancer (ClinicalTrials.gov ↗)
Biliary Tract Neoplasms Immunotherapy
Phase 2 Recruiting Peking Union Medical College Hospital China
NCT07718490 Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer (ClinicalTrials.gov ↗)
Metastatic Colorectal Cancer
Phase 2 Recruiting The First Affiliated Hospital with Nanjing Medical University China
NCT07731828 Neoadjuvant Short-course Hypofractionated Radiotherapy Plus Adebrelimab and Platinum Chemotherapy in Locally Advanced Cervical Cancer: A Single-arm Phase II Trial (ClinicalTrials.gov ↗)
Cervical Neoplasms
Phase 2 Recruiting The First Affiliated Hospital with Nanjing Medical University China
NCT07733830 Comparing ICI Followed By CCRT And CCRT Followed By Immunotherapy In Unresectable LA-ESCC (ClinicalTrials.gov ↗)
Esophageal Cancer
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
NCT07770113 A Random, Non-controlled, Open Clinical Study of Apatinib Mesylate Combined With Albumin-bound Paclitaxel ยฑ Adebrelimab in Treating Advanced Second-line Gastric Cancer (ClinicalTrials.gov ↗)
GC/GEJC
Phase 2 Recruiting The First Affiliated Hospital of Zhengzhou University China
NCT06222879 Study of HRS-8080 or SHR-A2009 Combined With Anti-tumor Therapy in Patients With Unresectable or Metastatic Breast Cancer (ClinicalTrials.gov ↗)
Breast Cancer
Phase 1/2 Recruiting Shandong Suncadia Medicine Co., Ltd. China
NCT06427239 Exploratory Clinical Study of HRS-4642 Combined With Adebrelimab in the Treatment of Advanced Pancreatic Ductal Adenocarcinoma (ClinicalTrials.gov ↗)
Pancreatic Cancer
Phase 1/2 Recruiting Fudan University China
NCT06474455 A Phase IB/II Clinical Study of SHR-9839 for Injection Combined With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors (ClinicalTrials.gov ↗)
Advanced Solid Tumors
Phase 1/2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT06512051 A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer (ClinicalTrials.gov ↗)
Advanced or Metastatic Non-small Cell Lung Cancer
Phase 1/2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT06589778 A Study of SHR-A2102 in Combination With Adebrelimab and SHR-8068 in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-Small Cell Lung Cancer
Phase 1/2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT06639347 A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial Carcinoma (ClinicalTrials.gov ↗)
Advanced Urothelial Carcinoma
Phase 1/2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT06754930 A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With NSCLC (ClinicalTrials.gov ↗)
Non-small Cell Lung Cancer (NSCLC)
Phase 1/2 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06776770 A Phase Ib/II Study of Adebrelimab in Combination with Capecitabine and Oxaliplatin in Cancer (ClinicalTrials.gov ↗)
Gastric Cancer
Phase 1/2 Recruiting Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center China
NCT06840002 A Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer (ClinicalTrials.gov ↗)
Ovarian Cancer
Phase 1/2 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06859775 SHR-A1811 Combination Regimen for the Treatment of Recurrent or Metastatic Cervical Cancer (ClinicalTrials.gov ↗)
Recurrent or Metastatic Cervical Cancer
Phase 1/2 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT07059221 A Trial of SHR-A2102 With Adebrelimab With or Without Other Anti-tumor Therapies in Recurrent/MetastaticHead and Neck Squamous Cell Carcinoma Cancer (ClinicalTrials.gov ↗)
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Phase 1/2 Recruiting Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT07105592 A Study of Nimotuzumab Plus Adebrelimab With Chemotherapy in Cisplatin-Ineligible Patients With Head And Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Head and Neck Squamous Cell Carcinoma
Phase 1/2 Recruiting Fudan University China
NCT07229586 A Study of SHR-7367 With Anti-tumor Agents in Patients With Solid Tumors (ClinicalTrials.gov ↗)
Solid Tumor
Phase 1/2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT07296341 HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors (ClinicalTrials.gov ↗)
Locally Advanced or Metastatic Pancreatic Cancer With
Phase 1/2 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT07595172 NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Ductal Adenocarcinoma (PDAC), Locally Advanced and Metastatic Pancreatic Cancer
Phase 1/2 Recruiting West China Hospital China
NCT06181032 A Study of Adebrelimab in Combination With Apatinib Gemcitabine and Cisplatin in Biliary Tract Malignancies (ClinicalTrials.gov ↗)
Biliary Tract Malignancies
Phase 1 Recruiting First Affiliated Hospital of Fujian Medical University China
NCT06332170 ARTEMIS-101: A Study of HS-20093 Combinations in Patients With Advanced Solid Tumors (ClinicalTrials.gov ↗)
Advanced Solid Tumor
Phase 1 Recruiting Hansoh BioMedical R&D Company China
NCT06336707 HS-20089 Combination Treatment in Subjects With Advanced Solid Tumors (ClinicalTrials.gov ↗)
Advanced Solid Tumors
Phase 1 Recruiting Hansoh BioMedical R&D Company China
NCT06350006 SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor (ClinicalTrials.gov ↗)
CLDN18.2-positive Advanced Solid Tumor
Phase 1 Recruiting Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT07434518 A Real-World Study Evaluating the Efficacy and Safety of Adebrelimab in Patients With Advanced SCLC (ClinicalTrials.gov ↗)
Small Cell Lung Cancer (SCLC)
Observational Recruiting Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine China
NCT07640048 Adjuvant Therapy for High-Risk Intrahepatic Cholangiocarcinoma: A Real-World Study (ClinicalTrials.gov ↗)
Intrahepatic Cholangiocarcinoma (Icc)
Observational Recruiting Peking Union Medical College Hospital China
NCT06853678 Second-line Immunotherapy for ES-SCLC (ClinicalTrials.gov ↗)
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Not applicable Recruiting Tianjin Medical University Cancer Institute and Hospital China
NCT06156267 Study of Personalized Tumour Vaccines and a PD-L1 Blocker in Patients With Surgically Resected Pancreatic Adenocarcino (ClinicalTrials.gov ↗)
Pancreatic Cancer
Phase EARLY_PHASE1 Not yet open Fudan University China
NCT07691762 A Study of TACE in Combination With SHR-8068, Adebrelimab, and Bevacizumab Versus TACE in Participants With Incurable Hepatocellular Carcinoma (ClinicalTrials.gov ↗)
Hepatocellular Carcinoma
Phase 3 Not yet open Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06177522 Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer, Neoadjuvant Therapy
Phase 2 Not yet open Jinling Hospital, China China
NCT06236997 Adebrelimab and Concurrent Radiochemotherapy as First-line Treatment for Extensive-stage Small-cell Lung Cancer (ClinicalTrials.gov ↗)
Small Cell Lung Carcinoma
Phase 2 Not yet open Henan Cancer Hospital China
NCT06592625 Neoadjuvant SHR-A1811 Plus Adebrelimab in HR Negative/Low & HER2 Low Breast Cancer Patients (ClinicalTrials.gov ↗)
Untreated Early-stage or Locally Advanced Breast Cancer
Phase 2 Not yet open Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06648525 Adebrelimab Combined with Irinotecan Liposomes, 5-FU, CF ยฑ Lenvatinib As First-line Treatment for Advanced ICC (ClinicalTrials.gov ↗)
Intrahepatic Cholangiocarcinoma (Icc)
Phase 2 Not yet open Harbin Medical University China
NCT06684158 Mecapegfilgrastim Combined With Adebrelimab and Chemotherapy as Neoadjuvant Therapy in Resectable GC/GEJC (ClinicalTrials.gov ↗)
GC/GEJC
Phase 2 Not yet open The First Affiliated Hospital with Nanjing Medical University China
NCT06786312 A Single-arm, Multicenter, Prospective Phase II Clinical Study of Apatinib in Combination With Adebrelimab and EC Regimen in the First-line Treatment of Extensive Small Cell Lung Cancer (ClinicalTrials.gov ↗)
Small Cell Lung Cancer Extensive Stage
Phase 2 Not yet open Fujian Cancer Hospital China
NCT07031154 A Single-arm, Multicenter, Prospective Clinical Study of Adebrelimab Combined With Apatinib Neoadjuvant Therapy for Resectable Non-small Cell Lung Cancer (ClinicalTrials.gov ↗)
Non-Small Cell Lung Cancer, Adebrelimab, Apatinib
Phase 2 Not yet open The First Affiliated Hospital of Xiamen University China
NCT07041437 Study of SHR-A2102 Combined Other Antitumor Drugs in Advanced Breast Cancer (ClinicalTrials.gov ↗)
Advanced Breast Cancer
Phase 2 Not yet open Fudan University China
NCT07317778 Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast Cancer (ClinicalTrials.gov ↗)
Breast Cancer Early Stage Breast Cancer (Stage 1-3), HR Positive/HER2 Low Breast Cancer
Phase 2 Not yet open Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
NCT07357532 Exploration of Treatment Strategies After Concurrent Chemoradiotherapy for LS-SCLC Guided by MRD (ClinicalTrials.gov ↗)
Small Cell Lung Carcinoma
Phase 2 Not yet open Peking University Cancer Hospital & Institute China
NCT07398560 Adebrelimab Combined With Oral Etoposide for Elderly Patients and Patients With Poor Performance Status in Small Cell Lung Cancer: An Exploratory Clinical Study (ClinicalTrials.gov ↗)
Small Cell Lung Cancer
Phase 2 Not yet open The Third Affiliated Hospital of Harbin Medical University China
NCT07466927 Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases (ClinicalTrials.gov ↗)
HER2-negative Breast Cancer
Phase 2 Not yet open Fudan University China
NCT07554768 Neoadjuvant Radio-immunotherapy Versus Immunotherapy Alone for Locally Advanced HNSCC (ClinicalTrials.gov ↗)
Head and Neck Squamous Cell Carcinoma, Locally Advanced Head and Neck Squamous Cell Carcinoma
Phase 2 Not yet open Chen Chunyan China
NCT07684040 A Study of Combination Therapy in Patients With Resectable Liver Cancer (ClinicalTrials.gov ↗)
Liver Cancer (Primary and Metastatic)
Phase 2 Not yet open Affiliated Hospital of Guangdong Medical University China
NCT07704645 The Clinical Study of Adalimumab Combined With Other Anti-tumor Therapy as a Treatment for Resectable Non-small Cell Lung Cancer (ClinicalTrials.gov ↗)
Resectable Non-small Cell Lung Cancer
Phase 2 Not yet open Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT07770672 An Exploratory Clinical Study of Accurate Efficacy Assessment of Neoadjuvant Immunotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma Based on 68Ga-FAPI ([68Ga] Fibroblast Activation Protein Inhibitor)/ยนโธF-FDG (2-Deoxy-2-[ยนโธF]Fluoro-D-glucose) Dual Imaging (ClinicalTrials.gov ↗)
Esophageal Cancer, ESCC
Phase 2 Not yet open Tan Lijie China
NCT07780721 Study of Adebrelimab Combined With Thymalfasin and Chemotherapy for Neoadjuvant Treatment of Esophageal Cancer (ClinicalTrials.gov ↗)
Esophageal Cancer
Phase 2 Not yet open The Affiliated Hospital of Putian University China
NCT07798947 A Phase II Clinical Study of SHR-7787 Injection Combined With SHR-1316 Injection in Patients With LS-SCLC (ClinicalTrials.gov ↗)
Limited-stage Small-cell Lung Cancer
Phase 2 Not yet open Shanghai Hengrui Pharmaceutical Co., Ltd. China
NCT07811375 Perioperative Adebrelimab for Locally Advanced Cervical Cancer (ClinicalTrials.gov ↗)
Locally Advanced Cervical Cancer
Phase 2 Not yet open Anhui Provincial Hospital China
NCT07736612 A Pan-RAS Inhibitor in Combination With Anti-Tumor Therapy in Participants With Advanced Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer, RAS Mutations or Amplifications
Phase 1/2 Not yet open Zhejiang University China
NCT07806058 An Open-Label, Multicenter, Phase IB/II Clinical Study of HRS-7172 in Combination With Antitumor Therapy in Participants With Solid Tumors (ClinicalTrials.gov ↗)
Pancreatic Cancer
Phase 1/2 Not yet open Jiangsu HengRui Medicine Co., Ltd. China
NCT06963502 A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Patients With Advanced Solid Tumors (ClinicalTrials.gov ↗)
Advanced Solid Tumors, Colorectal Cancer, Non-Small Cell Lung Cancer
Phase 1 Not yet open Jiangsu Hansoh Pharmaceutical Co., Ltd. China
NCT06773156 Adjuvant Adebrelimab Plus Apatinib After Chemoradiation in Limited-Stage Small Cell Lung Cancer (ClinicalTrials.gov ↗)
Limited-stage Small Cell Lung Cancer (LS-SCLC)
Phase 2 By invitation Second Affiliated Hospital of Nanchang University China
NCT06247956 Study of SHR-8068 Combined With Adebrelimab and Platinum-containing Chemotherapy in the Treatment of Advanced Gastric and Esophageal Cancer (ClinicalTrials.gov ↗)
Advanced Gastric Adenocarcinoma and Esophageal Squamous Cell Carcinoma
Phase 2 Active, closed Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06465563 SHR-8068 in Combination With Adebrelimab, Bevacizumab, and Platinum-Based Chemotherapy as First-line Treatment in Patients With Advanced Biliary Tract Cancer (ClinicalTrials.gov ↗)
Biliary Tract Cancer
Phase 2 Active, closed Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06599216 Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR + / HER2- Breast Cancer (ClinicalTrials.gov ↗)
Breast Cancer, HR+/HER2- Breast Cancer
Phase 2 Active, closed Harbin Medical University China
NCT06700421 Phase II Clinical Study of Adebrelimab Combined with Apatinib in the Treatment of Locally Advanced Non-small Cell Lung Cancer Patients with Radiation Pneumonitis (ClinicalTrials.gov ↗)
Unresectable Locally Advanced Non-small Cell Lung Cancer
Phase 2 Active, closed Wei Zhou China
NCT06766019 Adebrelimab Combined With Irinotecan Liposomal (II), Oxaliplatin, and 5-FU/LV Conversion Therapy for Locally Advanced Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer
Phase 2 Active, closed The First Affiliated Hospital with Nanjing Medical University China
NCT07071714 A Phase II Study of SHR-8068 Injection in Combination With Anti-tumor Therapies in Colorectal Cancer (ClinicalTrials.gov ↗)
Colorectal Cancer
Phase 2 Active, closed Suzhou Suncadia Biopharmaceuticals Co., Ltd. China
NCT06385678 A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation (ClinicalTrials.gov ↗)
Advanced KRAS G12D Mutant Solid Tumors
Phase 1/2 Active, closed Jiangsu HengRui Medicine Co., Ltd. China
NCT07009457 A Clinical Study of SHR-1316 (SC) Combined With Carboplatin and Etoposide as First-line Treatment for Extensive Stage Small Cell Lung Cancer (ClinicalTrials.gov ↗)
Widespread Small Cell Lung Cancer
Phase 1 Active, closed Suzhou Suncadia Biopharmaceuticals Co., Ltd. China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

104 conditions
Condition (as registered)Trials
Pancreatic Cancer7
Esophageal Cancer4
Breast Cancer4
Advanced Solid Tumors4
Non-Small Cell Lung Cancer3
Colorectal Cancer3
GC/GEJC3
Biliary Tract Cancer3
Small Cell Lung Cancer (SCLC)2
Esophageal Squamous Cell Carcinoma2
Nasopharyngeal Carcinoma2
Biliary Tract Neoplasms Immunotherapy2
Hepatocellular Carcinoma2
Head and Neck Squamous Cell Carcinoma2
Advanced Urothelial Carcinoma2
Gastric Cancer2
HR Positive/HER2 Low Breast Cancer2
Small Cell Lung Carcinoma2
Intrahepatic Cholangiocarcinoma (Icc)2
Small Cell Lung Cancer Extensive Stage2
Resectable Non-small Cell Lung Cancer1
Advanced Breast Cancer1
Immunotherapy1
Biomarkers1
Squamous Cell Carcinoma of Head and Neck1
Pancreatic Ductal Adenocarcinoma (PDAC)1
Locally Advanced and Metastatic Pancreatic Cancer1
Nasopharyngeal Cancer1
Advanced Hepatocellular Carcinoma1
Cervical Neoplasms1
Advanced Gastric Adenocarcinoma and Esophageal Squamous Cell Carcinoma1
Non Small Cell Lung Cancer1
Triple Negative Breast Cancer1
ESCC1
Adebrelimab1
Apatinib1
SCLC,Extensive Stage1
Vitamin C1
GLUT31
Liver Cancer (Primary and Metastatic)1

+ 64 more conditions in the trial records above.

03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Suzhou Suncadia Biopharmaceuticals Co., Ltd.16
Shanghai Hengrui Pharmaceutical Co., Ltd.11
Fudan University8
The First Affiliated Hospital with Nanjing Medical University6
Tang-Du Hospital4
Sun Yat-sen University3
Peking Union Medical College Hospital3
Tianjin Medical University Cancer Institute and Hospital3
Jiangsu HengRui Medicine Co., Ltd.3
The Affiliated Hospital of Putian University2
The First Affiliated Hospital of Xiamen University2
Hansoh BioMedical R&D Company2
Harbin Medical University2
Peking University Cancer Hospital & Institute2
Ruijin Hospital2
Henan Cancer Hospital2
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine1
Fujian Medical University Union Hospital1
Xiuping Ding1
West China Hospital1
Zeng Jian1
Mian XI1
Tan Lijie1
Affiliated Hospital of Guangdong Medical University1
Second Affiliated Hospital, Zhejiang University, School of Medicine1
Zhejiang University1
Shanghai Jiao Tong University School of Medicine1
The First Affiliated Hospital of Zhengzhou University1
Nanfang Hospital, Southern Medical University1
RenJi Hospital1
Jinling Hospital, China1
Chen Chunyan1
Air Force Military Medical University, China1
Jiangsu Hansoh Pharmaceutical Co., Ltd.1
Tongji Hospital1
Jun Jia1
The Fourth Affiliated Hospital of Zhejiang University School of Medicine1
Jiang Long1
Yongjun Chen1
Sir Run Run Shaw Hospital1
Anhui Provincial Hospital1
Jin Ying1
Cancer Institute and Hospital, Chinese Academy of Medical Sciences1
Sichuan University1
Hospital of Stomatology, Wuhan University1
The Third Affiliated Hospital of Harbin Medical University1
Obstetrics & Gynecology Hospital of Fudan University1
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center1
Second Affiliated Hospital of Nanchang University1
First Affiliated Hospital of Fujian Medical University1
Fujian Cancer Hospital1
Feng Tian1
Shengjing Hospital1
Wei Zhou1
Shandong Suncadia Medicine Co., Ltd.1
04

Trials by country register

RegisterAdebrelimab trials
Clinical trials in China110

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Adebrelimab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Adebrelimab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.