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Trackers› Clinical trials› Rectal Cancer
Clinical trial register · China

Rectal Cancer Trials in China, 2026

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 19052 matching records held by the registry are in this view. Synced 22 Sep 2026, 11:10 UTC
19052
Studies in scope
all four open statuses
11786
Recruiting now
open to new participants
2009
Lead sponsors
across recruiting studies
Top sites
Guangzhou 22 Shanghai 21 Beijing 14 Wuhan 9 Hangzhou 7
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Sun Yat-sen University9 Fudan University8 Sixth Affiliated Hospital, Sun Yat-sen University6 Ruijin Hospital4 West China Hospital3
Site location
Guangzhou22 Shanghai21 Beijing14 Wuhan9 Hangzhou7
All 31 locations
Target enrolment
to

Rectal Cancer trials in China

95 of 19052 studies
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Status
Study
Lead sponsor
Phase
Enrol
Chinese sites
Start
Not yet open
Radiotherapy Combined With Capeox Chemotherapy, Sintilimab and Suvemcitug in Locally Advanced pMMR Rectal Cancer:a Prospective Clinical Trial
NCT07774754Rectal Cancer
Sun Yat-sen University
Phase 2
18
Guangzhou
2026-09-01
Not yet open
Total Neoadjuvant mFOLFOX6 Plus Suvemcitug and Enlonstobart With Selective Omission of Pelvic Radiotherapy for High-Risk Mid-Rectal Locally Advanced Rectal Cancer
NCT07810114Rectal Cancer
DrugsEnlonstobart·MFOLFOX6
Fudan University
Phase 2
52
Shanghai
2026-08-28
Not yet open
Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)
NCT07306390Colon Cancer, Rectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Observational
1,200
Beijing
2026-07-01
Not yet open
Concordance Between Large Language Model and Multidisciplinary Team Recommendations in Rectal Cancer
NCT07595107Rectal Cancer
Shandong Cancer Hospital and Institute
Observational
180
Jinan
2026-06-01
Not yet open
Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial
NCT07527520Rectal Cancer, Moderately Hypofractionated Radiotherapy, Serplulimab, pMMR/MSS
DrugSerplulimab
Fudan University
Phase 2
165
Shanghai
2026-06
Recruiting
Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC
NCT07646639Rectal Cancer, Radiotherapy
DrugsIL-2·Capox·Tislelizumab
The First Affiliated Hospital with Nanjing Medical University
Phase 2
122
Nanjing
2026-05-20
Recruiting
A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer
NCT07113275Rectal Cancer, Total Neoadjuvant Therapy, Radiotherapy, Immunotherapy
DrugsSerplulimab·Oxaliplatin·Capecitabine
Tao Zhang
Phase 3
444
Wuhan
2026-05-15
Recruiting
Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial
NCT07594925Rectal Cancer
DrugTislelizumab
Tianjin Medical University Cancer Institute and Hospital
Phase 2
130
Tianjin
2026-05-01
Recruiting
Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer
NCT07528209Rectal Cancer, pMMR (Microsatellite Stable Rectal Cancer)
DrugCapox
Sun Yat-sen University
Phase 3
556
Guangzhou
2026-04-20
Recruiting
Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a Single-Center, Prospective Randomized Controlled Trial.
NCT07537998Low Anterior Resection Syndrome, Rectal Cancer
Pei-Rong Ding
Phase 2/3
160
Guangzhou
2026-04-10
Recruiting
The Impact of Two-Stage Turnbull-Cutait Pull-Through Coloanal Anastomosis on Stoma-free Survival in Low Rectal Anal-preserving Surgery
NCT07369531Rectal Cancer, Surgical Anastomosis, Survival , Tumor, Anal Function
The First Hospital of Jilin University
Not applicable
520
Changchun
2026-03-18
Recruiting
Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Without Concurrent Surufatinib in Neoadjuvant Therapy for Mid-to-low Localized Rectal Cancer of High-risk Criteria
NCT07505472Rectal Cancer
The First Hospital of Jilin University
Phase 2/3
212
Changchun
2026-02-23
Not yet open
Effect of Individualized Catheter Management on Early Removal After Rectal Cancer Surgery
NCT07346586Urinary Catheters, Rectal Cancer, Urinary Retention
The First Hospital of Jilin University
Not applicable
1,545
Changchun
2026-02-20
Recruiting
A Study on the Accurate Evaluation of Pseudoprogression of Rectal Cancer Immunotherapy Based on Multitemporal and Multiparameter MRI
NCT07381322Rectal Cancer
Peiyi Xie
Observational
300
Guangzhou, Maoming
2026-02-01
Recruiting
A Pilot Study Evaluating ฮฒ-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer
NCT07239466Rectal Cancer, Radiotherapy, Immunotherapy, Chemotherapy
DrugsOxaliplatin·Capecitabine
Tao Zhang
Phase 2
25
Wuhan
2026-01-01
Not yet open
SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer
NCT07297030Rectal Cancer
DrugCapox
Sun Yat-sen University
Phase 2
37
Guangzhou
2025-12-20
Recruiting
Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection
NCT07605611Rectal Cancer, Anastomotic Leakage
DrugSomatostatin
Tongji Hospital
Not applicable
72
Ezhou, Wuhan
2025-11-17
Recruiting
SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer
NCT07162714Rectal Cancer, Radiation, AK112
DrugBevacizumab
Zhejiang Cancer Hospital
Phase 2
30
Hangzhou
2025-10-27
Recruiting
SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak
NCT07209787Rectal Cancer
Beijing Chao Yang Hospital
Phase 4
966
Beijing
2025-10-21
Recruiting
Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement
NCT07104604Rectal Cancer
DrugsLiposomal Irinotecan·Capecitabine·Tislelizumab
Affiliated Cancer Hospital of Shantou University Medical College
Phase 2
51
Shantou
2025-10-20
Recruiting
The Impact of Probiotic Intervention on the Gut Microbiota and Bowel Function
NCT07369830Rectal Cancer
DrugClostridium butyricum , Live
Huashan Hospital
Not applicable
156
Shanghai
2025-10-15
Recruiting
Node-Sparing Short-Course Radiation Combined With Capecitabine and PD-1/CTLA-4 for MSS Early Rectal Cancer
NCT07068763Rectal Cancer
DrugCapecitabine
Sir Run Run Shaw Hospital
Phase 2
52
Hangzhou
2025-10-09
Recruiting
Response-adapted Total Neoadjuvant Therapy Guided by Induction Chemotherapy in Early- and Intermediate-risk Low Rectal Cancer for Implementation of a Watch-and-wait Strategy
NCT07260526Rectal Cancer
West China Hospital
Observational
60
Chengdu
2025-10-01
Not yet open
Neoadjuvant Chemoradiotherapy Combined With Immunotherapy and Anti-angiogenesis in Treating Locally Advanced Rectal Cancer
NCT07134218Rectal Cancer
Changhai Hospital
Phase 2/3
180
Shanghai
2025-10
Recruiting
SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC
NCT07284992Rectal Cancer, Advanced Stage Colorectal Cancer, Radiotherapy
Shandong Provincial Hospital
Phase 2
208
Jinan
2025-09-12
Recruiting
CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors
NCT07179692Lung Cancer, Gastric Cancer, Colon Cancer, Rectal Cancer
Chongqing Precision Biotech Co., Ltd
Phase 1
108
Hefei
2025-09-12
Recruiting
SCRT Followed by CAPOX + Bev ยฑ PD-1 Inhibitor for TNT in LARC
NCT07198165Rectal Cancer, Rectal Adenocarcinoma, Rectal Cancer, Radiotherapy, Rectal Cancer Patients
Ruijin Hospital
Phase 2
104
Shanghai
2025-09-05
Not yet open
Low Powered Colorectal Anastomosis After Rectal Excision (OASIS)
NCT07146334Rectal Cancer, Surgery Indication
Bordeaux Colorectal Institute
Observational
400
Shanghai
2025-09
Recruiting
Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 Study
NCT07132463Rectal Cancer
DrugsCapox·Tislelizumab
Fudan University
Phase 3
196
Shanghai
2025-08-12
Recruiting
Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial
NCT06850090Rectal Cancer, Rectal Cancer Patients
Shandong Cancer Hospital and Institute
Phase 3
210
Jinan
2025-07-30
Recruiting
Efficacy and Safety of Trastuzumab Biosimilars and Pertuzumab Biosimilars Combined With Chemotherapy for Neoadjuvant Treatment of Patients With Locally Advanced HER2-positive Rectal Cancer
NCT07108127Rectal Cancer, HER2-positive
DrugXelox
Peking Union Medical College Hospital
Phase 2
24
Beijing
2025-06-20
Recruiting
Leucine Plus Radiochemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer
NCT07359989Rectal Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine
Not applicable
33
Hangzhou
2025-06-11
Not yet open
Preservation Vs. Dissection of No. 253 Lymph Nodes of Robotic Resection for Mid/Low Rectal Cancer
NCT06956976Rectal Cancer
Fudan University
Not applicable
1,596
Shanghai
2025-06-01
Recruiting
Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)
NCT06958432Rectal Cancer, Neoadjuvant Therapies, Immune Checkpoint Therapy, Radiotherapy
Sixth Affiliated Hospital, Sun Yat-sen University
Phase 2/3
430
Guangzhou
2025-05-01
Not yet open
Safety and Efficacy Study of Single-port Robotic Versus Multi-port Robotic Radical Rectal Cancer Surgery
NCT06943690Rectal Cancer, Surgery
Ruijin Hospital
Not applicable
212
Luoyang, Jinan, Shanghai, Wenzhou
2025-05
Recruiting
Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)
NCT06923345Rectal Cancer, Neoadjuvant Therapies, Immune Checkpoint Therapy, Radiotherapy
Sixth Affiliated Hospital, Sun Yat-sen University
Phase 2
80
Guangzhou
2025-03-31
Active, closed
Autologous Fecal Microbiota Transplantation for Anal Function Recovery After Ileostomy Reversal in Rectal Cancer
NCT07711509Rectal Cancer, Low Anterior Resection Syndrome, Fecal Incontinence, Diversion Colitis
Peking University People's Hospital
Not applicable
35
Beijing
2025-03-25
Recruiting
Neoadjuvant Short-Course Radiotherapy With or Without Chemotherapy and AK112 in Locally Advanced Rectal Cancer
NCT06718543Rectal Cancer
DrugCapeox
fan li
Phase 2
100
Chongqing
2025-02-10
Recruiting
Rectal Cancer Neoadjuvant Therapy-Real World Study
NCT07566559Rectal Cancer
Beijing Friendship Hospital
Observational
869
Beijing
2025-01-01
Active, closed
the Effect of Environmental Factors on Colorectal Cancer Based on Macrogenomes
NCT06852495Colon Cancer, Rectal Cancer
Dong Peng
Observational
200
Chongqing
2024-11-01
Recruiting
Planed Organ Preservation for Low Rectal Cancer After Neoadjuvant Chemotherapy (OPLAR)
NCT07070622Rectal Cancer
West China Hospital
Phase 3
186
Chengdu
2024-11-01
Recruiting
Application of Amide Proton Transfer-Weighted Imaging in Predicting Pathological Complete Response After Neoadjuvant Therapy of Rectal Cancer
NCT06719414Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University
Observational
320
Guangzhou, Maoming
2024-10-22
Recruiting
Virtual Ileostomy Versus Diverting Ileostomy in Patients Undergoing Total Mesorectal Excision
NCT06633133Rectal Cancer
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Not applicable
620
Chongqing
2024-10-10
Active, closed
Neoadjuvant Short-Course Radiotherapy Followed by CAPOX Plus PD-1 Antibody and IL-2 in Locally Advanced Rectal Cancer (PRIDE01)
NCT06577194Rectal Cancer, Advanced Solid Tumor
DrugsIL-2·Capox·Tislelizumab
The First Affiliated Hospital with Nanjing Medical University
Phase 2
35
Nanjing
2024-10-09
Not yet open
Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC
NCT06599827Rectal Cancer
Shanghai Zhongshan Hospital
Phase 2
54
Shanghai
2024-09-20
Recruiting
Pucotenlimab Plus Radiotherapy and Chemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cance(PUCRT)
NCT06770270Rectal Cancer
DrugPucotenlimab
Second Affiliated Hospital, Zhejiang University, School of Medicine
Phase 2
68
Hangzhou
2024-08-01
Active, closed
Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer
NCT06507371Rectal Cancer
DrugsOxaliplatin·Capecitabine·Tislelizumab
Sir Run Run Shaw Hospital
Phase 3
170
Hanzhou
2024-07-29
Recruiting
Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC
NCT06542588Rectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Phase 2
29
Wuhan, Hubei
2024-07-19
Not yet open
Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer
NCT06443671Rectal Cancer
DrugCapeox
Peking University Cancer Hospital & Institute
Phase 2/3
132
Beijing
2024-06-01
Recruiting
Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)
NCT06455124Rectal Cancer
DrugsOxaliplatin·Capecitabine·Tislelizumab
Fudan University
Phase 2
60
Shanghai
2024-05-08
Active, closed
A Clinical Trial Comparing Staged Turnbull-Cutait Pull-through Anastomosis With Direct Anastomosis Plus Prophylactic Ileostomy in the Treatment of Low Rectal Cancer After Internal Sphincter Resection
NCT06662643Rectal Cancer, Rectal Carcinoma
Zhongnan Hospital
Not applicable
110
Wuhan
2024-05-08
Not yet open
Study of Fruquintinib Combined With Tegafur Gimeracil Oteracil in Patients With Metastatic Colorectal Cancer
NCT06255379Metastasis Colorectal Cancer, Colon Cancer, Rectal Cancer
DrugsFuquinitinib·Tegafur Gimeracil Oteracil
Guangzhou University of Traditional Chinese Medicine
Phase 2
52
Guangzhou
2024-05-06
Recruiting
The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer
NCT06254521Rectal Cancer, Rectal Cancer Stage II, Rectal Cancer Stage III
DrugTislelizumab
First Affiliated Hospital of Guangxi Medical University
Phase 2
60
Nanning
2024-02-22
Active, closed
Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer
NCT06210971Rectal Cancer
DrugsLiposomal Irinotecan·Capecitabine
Hebei Medical University Fourth Hospital
Phase 2
60
Shijiazhuang
2024-02-01
Recruiting
Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer
NCT06209099Rectal Cancer
Peking University Cancer Hospital & Institute
Not applicable
96
Beijing
2024-01-17
Recruiting
Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy
NCT05965531Rectal Cancer
DrugTrifluridine/Tipiracil
Sun Yat-sen University
Phase 2
65
Guangzhou
2024-01-01
Recruiting
Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy
NCT07561060Rectal Cancer
DrugsOxaliplatin·Capecitabine·Tislelizumab
Fudan University
Phase 1/2
50
Shanghai
2024-01-01
Recruiting
Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer
NCT06765616Rectal Cancer, Advanced Stage Colorectal Cancer, Radiotherapy
DrugAdebrelimab
Feng Tian
Phase 2
31
Jinan
2024-01-01
Recruiting
Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H)
NCT06146946Rectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Not applicable
1,384
Beijing, Shanghai, Chengdu
2023-12-01
Active, closed
Adaptive Boost Radiotherapy to Primary Lesions and Positive Nodes in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer
NCT06246344Rectal Cancer
DrugsCapeox·Capecitabine
Shandong Cancer Hospital and Institute
Phase 3
128
Jinan
2023-12-01
Recruiting
Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes๏ผˆCAR-T๏ผ‰ for CEA Positive Advanced Malignant Solid Tumors
NCT06126406Gastric Cancer, Colon Cancer, Rectal Cancer, Breast Cancer
Chongqing Precision Biotech Co., Ltd
Phase 1
60
Wuhu
2023-11-06
Recruiting
Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients
NCT06043999Chemotherapy Effect, Rectal Cancer
Sun Yat-sen University
Not applicable
392
Guangzhou
2023-09-01
Not yet open
Organ Preservation Following Enverolimab-based Total Neoadjuvant Therapy for Locally Advanced Very Low Rectal Cancer
NCT05969847Rectal Cancer
DrugsCapecitabine, Oxaliplatin·Envafolimab·Capox
ๆฑ ็•”
Phase 2
72
Fuzhou
2023-08-15
Recruiting
Reasons for Non-reversal of Temporary Stomas After Surgeries of Mid-low Rectal Cancer ๏ผˆNORESTO Study๏ผ‰
NCT06194708Rectal Cancer
Peking Union Medical College Hospital
Observational
235
Beijing
2023-05-15
Not yet open
Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion
NCT05807984Rectal Cancer, Recurrent
Xin Cai
Phase 2
31
Shanghai
2023-05-01
Recruiting
Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma
NCT05752136Rectal Cancer
DrugEnvafolimab
Sir Run Run Shaw Hospital
Phase 3
108
Hangzhou
2023-04-01
Recruiting
Total Neoadjuvant Treatment ยฑImmunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)
NCT06229041Rectal Cancer
Peking University Cancer Hospital & Institute
Phase 3
472
Beijing
2023-03-29
Recruiting
SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer
NCT05576480Rectal Cancer, Locally Advanced
DrugsCapeox·Penpulimab
Ruijin Hospital
Phase 2
55
Shanghai
2023-02-06
Recruiting
Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma
NCT05563922Rectal Cancer
Shanghai Zhongshan Hospital
Phase 2
56
Shanghai
2022-09-01
Recruiting
Chinese Colorectal Cancer Database
NCT05434026Colonic Cancer, Rectal Cancer, Prospective Studies
Beijing Friendship Hospital
Observational
200,000
Beijing
2022-08-03
Recruiting
Short-course Radiotherapy (5ร—6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer
NCT03466424Radiation Oncology, Rectal Cancer
Fujian Medical University Union Hospital
Observational
9
Fuzhou
2022-08-01
Recruiting
The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer
NCT05984485Rectal Cancer
Sun Yat-sen University
Phase 3
766
Chongqing, Guangzhou, Hengyang, Shenyang, Xi'an, Nanchong
2022-07-05
Recruiting
Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI
NCT05523245Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University
Observational
1,700
Guangzhou, Zhuhai
2022-06-24
Active, closed
Clinical Study on the Safety and Relationship of Sintilimab Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma
NCT07127497Pathological Complete Response, Rectal Cancer, Neoadjuvant Chemoimmunotherapy
DrugsXelox·Tislelizumab
The First Affiliated Hospital of Anhui Medical University
Phase 2
50
Hefei
2022-06-01
Active, closed
A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer
NCT05009069Rectal Neoplasms, Rectal Cancer
DrugsTiragolumab·Atezolizumab·Capecitabine·Bevacizumab
Hoffmann-La Roche
Phase 2
58
Beijing, Guangzhou, Hangzhou, Shanghai, Shenyang
2022-03-18
Recruiting
Neoadjuvant Chemoradiotherapy Plus Sintilimab for Intermediate/High Immunoscore Locally Advanced Rectal Cancer
NCT05450029Rectal Cancer
DrugTislelizumab
Yanhong Deng
Phase 2
51
Guangzhou
2022-01-01
By invitation
Chemotherapy Combined With High-dose Radiotherapy for Low Rectal Cancer Using MR Guided Linear Accelerator
NCT05338866Rectal Cancer
Sun Yat-sen University
Observational
58
Guangzhou
2022-01-01
Recruiting
Multicenter Study on Postoperative Urinary and Sexual Function During Laparoscopic Functional Total Mesorectum Excision
NCT05049317Rectal Cancer
Renmin Hospital of Wuhan University
Not applicable
88
Wuhan
2021-11-24
Recruiting
Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy
NCT05316103Rectal Cancer
Nanfang Hospital, Southern Medical University
Not applicable
68
Guangzhou
2021-11-04
Recruiting
Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer
NCT04098471Rectal Cancer
The First Affiliated Hospital with Nanjing Medical University
Not applicable
168
Nanjing
2021-10-01
Recruiting
Artificial Intelligence Assists Surgeons' Decision Making
NCT04999007Rectal Cancer
Jichao Qin
Not applicable
616
Wuhan
2021-09-02
Recruiting
Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer
NCT05424692Colon Cancer, Rectal Cancer, Chemotherapy Effect, PTC
DrugBevacizumab
Peking Union Medical College Hospital
Not applicable
200
Beijing
2021-09-01
Recruiting
Neoadjuvant FOLFOXIRI Versus CapeOX Chemotherapy for Local Advanced Rectal Cancer
NCT05201430Rectal Cancer
Fudan University
Phase 3
300
Shanghai
2021-08-27
Active, closed
Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer
NCT04922853Rectal Cancer, Neoadjuvant Chemotherapy
West China Hospital
Phase 3
554
Wuxi, Chengdu, Kunming
2021-08-26
Active, closed
Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION)
NCT04928807Rectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Phase 3
231
Wuhan
2021-07-20
Recruiting
Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer
NCT04527861Colorectal Cancer, Colon Cancer, Rectal Cancer
Ruijin Hospital
Not applicable
710
Lanzhou, Shenyang, Jinan, Chengdu, Hangzhou, Shanghai
2021-04-08
Active, closed
Robotic Versus Laparoscopic Surgery for Middle and Low Rectal Cancer: a Target Trial Emulation
NCT06814093Rectal Cancer
Xu jianmin
Observational
2,702
Shanghai
2021-01-01
Recruiting
Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer
NCT04643041Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University
Not applicable
47
Guangzhou
2021-01-01
Recruiting
Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer
NCT04743102Rectal Cancer, Neoadjuvant Therapy, Complete Remission, Metastasis
Beijing Chao Yang Hospital
Not applicable
260
Beijing
2021-01-01
Not yet open
An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal Cancer
NCT04443543Rectal Cancer
Drugs5Fluorouracil·Irinotecan·Oxaliplatin·Tislelizumab
Fudan University
Phase 2
222
Shanghai
2020-06-22
Recruiting
Neoadjuvant mFOLFOXIRI Plus Bevacizumab in Patients With High-Risk Locally Advanced Rectal Cancer
NCT04215731Rectal Cancer
DrugsLeucovorin·Irinotecan·Oxaliplatin·Bevacizumab
Yanhong Deng
Phase 3
582
Guangzhou
2020-03-27
Active, closed
TNT to Increase the Clinical Complete Response Rate for Distal LARC
NCT03840239Rectal Cancer, Rectal Cancer Stage II, Rectal Cancer Stage III, Chemoradiation
DrugCapecitabine, Oxaliplatin
Sun Yat-sen University
Phase 2
98
Guangzhou
2018-12-25
Recruiting
Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation
NCT03671252Rectal Cancer
DrugsFolfoxiri·Xelox
Sun Yat-sen University
Phase 3
776
Guangzhou
2018-11-16
Recruiting
Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer
NCT03573791Rectal Cancer, Cancer of Rectum, Cancer of the Rectum, Neoplasms, Rectal
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Observational
152
Wuhan
2018-05-21
Recruiting
Proximally Extended Resection for Rectal Cancer After Neoadjuvant Chemoradiotherapy
NCT02649647Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University
Not applicable
240
Guangzhou
2016-02
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 25 September 2026. https://priyalifescience.com/clinical-trials-china/condition/rectal-cancer

Query this register directly
GET /api/trials?country=cn&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,052 studies in total at the last sync on 22 Sep 2026, 11:10 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 95 of those studies listing the condition Rectal Cancer.

How many Rectal Cancer trials are recruiting in China?

64 of the 95 studies on this page are recruiting new participants as of the 22 Sep 2026, 11:10 UTC sync. A further 17 have not yet opened recruitment, 13 are active but closed to new participants, and 1 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Rectal Cancer), 95 studies
PhaseStudiesRecruitingShare
Phase 2342035.8%
Not applicable221723.2%
Observational15915.8%
Phase 3151115.8%
Phase 2/3535.3%
Phase 1222.1%
Phase 1/2111.1%
Phase 4111.1%

Most active sponsors

Lead sponsors with the most studies (Rectal Cancer)
Lead sponsorStudiesRecruiting
Sun Yat-sen University95
Fudan University84
Sixth Affiliated Hospital, Sun Yat-sen University66
Ruijin Hospital43
Peking Union Medical College Hospital33
Peking University Cancer Hospital & Institute32
Shandong Cancer Hospital and Institute31
Sir Run Run Shaw Hospital32
The First Affiliated Hospital with Nanjing Medical University32
The First Hospital of Jilin University32
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.