Ireland
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Active, not recruiting Observational

the Effect of Environmental Factors on Colorectal Cancer Based on Macrogenomes

NCT06852495 · tracked via the Priya Life Science China tracker
Sponsor
Phase
Observational
Started
2024-11-01
Last updated
2025-02-28

Condition(s) studied

Colon CancerRectal Cancer

Study summary

The aim of this study is to investigate the effects of environmental factors, such as air pollution, on the occurrence, development and prognosis of colorectal cancer; to identify metabolic markers specific to colorectal cancer patients, which will provide a basis for early diagnosis, early intervention and individualized treatment; and to comprehensively understand the mechanism of the occurrence and development of colorectal cancer by integrating the data of environmental factors and the macro-genome, and to develop new predictive and therapeutic strategies.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Age ≥18 years old; * Patients diagnosed with colorectal cancer by pathologic biopsy before surgery; * Patients did not undergo chemotherapy, radiotherapy, targeted and immunotherapy, etc. before enrollment; * Willing to participate in the study and sign an informed consent form. Complete clinical data. Exclusion Criteria: * Concurrent primary malignant tumor other than colorectal cancer; * Patients with severe cardiopulmonary insufficiency or other systemic diseases that affect the choice of treatment plan; * Inappropriate for enrollment as assessed by the investigator; * Incomplete clinical data.

Primary outcome measure(s)

  • prognosis — From date of diagnosis until the date of death from any cause or or loss to follow-up, whichever came first, assessed up to 60 months
    Overall survival (OS), from date of diagnosis until the date of death from any cause or or loss to follow-up, whichever came first.

Trial sites (1)

FacilityCityRegionStatus
The First Affiliated Hospital of Chongqing Medical University Chongqing Chongqing Municipality
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06852495 on ClinicalTrials.gov ↗ ← All trials in China