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Priya Life Science Compound trial record
Compound · clinical trials

Liposomal Irinotecan clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 18 trials in our China, USA, France, Spain, Japan, Germany, South Korea, Taiwan, UK, Poland, Brazil, Israel, Italy, Netherlands and Mexico registers that name Liposomal Irinotecan as an intervention. Synced 9 Nov 2026
18Current trials
7Recruiting now
16Lead sponsors
15Country registers
At a glance

Liposomal Irinotecan is named as an intervention in 18 current clinical trials in our China, USA, France, Spain, Japan, Germany, South Korea, Taiwan, UK, Poland, Brazil, Israel, Italy, Netherlands and Mexico registers. 7 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Hebei Medical University Fourth Hospital (3). The most-studied condition is Pancreatic Cancer.

Patient leaflets for Liposomal Irinotecan

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting739%
  • Not yet open633%
  • Active, closed528%

Trials by phase

  • Phase 2950%
  • Phase 3317%
  • Phase 1211%
  • Phase 1/2211%
  • Not applicable16%
  • Phase 2/316%
01

Clinical trials of Liposomal Irinotecan

18 trials
StudyPhaseStatusLead sponsorRegisters
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
NCT07409272 · Pancreatic Cancer, Metastatic Pancreatic Cancer, Metastatic Pancreatic Adenocarcinoma
Phase 3 Recruiting Astellas Pharma Global Development, Inc UK, USA, China, Germany, France, Spain, Poland, Brazil, Japan, South Korea, Taiwan
Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer
NCT06184698 · ClinicalTrials.gov ↗ · Colorectal Cancer
Phase 2 Recruiting Hebei Medical University Fourth Hospital China
Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement
NCT07104604 · ClinicalTrials.gov ↗ · Rectal Cancer
Phase 2 Recruiting Affiliated Cancer Hospital of Shantou University Medical College China
Intraperitoneal Injection of Liposomal Irinotecan as Monotherapy or in Combination With Recombinant Mutant Human Tumor Necrosis Factor or Bevacizumab for the Treatment of Malignant Ascites Following Failure of Prior Standard Therapy
NCT07397819 · ClinicalTrials.gov ↗ · Malignant Ascites
Phase 1/2 Recruiting Dong sheng Zhang China
Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma
NCT07479732 · ClinicalTrials.gov ↗ · Osteosarcoma, Osteosarcoma Metastatic
Phase 1/2 Recruiting Peking University People's Hospital China
A Study of ASP3082 in Adults With Advanced Solid Tumors
NCT05382559 · Solid Tumor
Phase 1 Recruiting Astellas Pharma Inc USA, China, France, Spain, Japan, South Korea, Israel
SCRT-NALIRIXELOX+Sintilimab as TNT for High-Risk LARC
NCT07474103 · Rectal Cancer, Adenocarcinoma
Not applicable Recruiting Union Hospital, Tongji Medical College, Huazhong University of Science and Technology China
A Study to Compare the Efficacy and Safety of YL201 With Standard Chemotherapy in Patients With Metastatic Pancreatic Cancer After Failure of Gemcitabine-Based Systemic Chemotherapy
NCT07803783 · ClinicalTrials.gov ↗ · Metastatic Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma (PDAC)
Phase 3 Not yet open MediLink Therapeutics (Suzhou) Co., Ltd China
A Clinical Study of Liposomal Irinotecan for Second-Line Therapy in Metastatic Colorectal Cancer
NCT07585279 · ClinicalTrials.gov ↗ · Metastatic Colorectal Cancer (CRC), Liposomal Irinotecan, Second-Line
Phase 2/3 Not yet open Hebei Medical University Fourth Hospital China
A Randomized, Two-cohort, Prospective Phase II Clinical Study of the Second-line Treatment of Advanced Biliary System Tumors With Liposomal Irinotecan (II) Combination Regimen
NCT07099794 · ClinicalTrials.gov ↗ · Biliary Tract Cancer (BTC)
Phase 2 Not yet open Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
Short-Course Radiotherapy, Nal-IRI, Capecitabine, and Camrelizumab for Locally Advanced MSS Rectal Cancer
NCT07521605 · ClinicalTrials.gov ↗ · Rectal Cancer Patients
Phase 2 Not yet open Guangdong Provincial People's Hospital China
SHR-1701 in Combination With Irinotecan Liposome (II) for Second-line Treatment of ESCC After Immunotherapy
NCT07524374 · ClinicalTrials.gov ↗ · ESCC
Phase 2 Not yet open Zhigang Li China
Liposomal Irinotecan Plus Cisplatin in Patients With Advanced or Metastatic Solid Malignancies
NCT07782346 · ClinicalTrials.gov ↗ · Advanced Solid Malignancies
Phase 1 Not yet open National Health Research Institutes, Taiwan China, Taiwan
Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
NCT06625320 · Pancreatic Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma
Phase 3 Active, closed Revolution Medicines, Inc USA, Germany, France, Spain, Italy, Japan
Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer
NCT03764553 · ClinicalTrials.gov ↗ · Esophageal Cancer
Phase 2 Active, closed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Netherlands
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread
NCT04233866 · ClinicalTrials.gov ↗ · Metastatic Pancreatic Adenocarcinoma, Stage IV Pancreatic Cancer AJCC v8
Phase 2 Active, closed ECOG-ACRIN Cancer Research Group Mexico
Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer
NCT06210971 · ClinicalTrials.gov ↗ · Rectal Cancer
Phase 2 Active, closed Hebei Medical University Fourth Hospital China
Gemcitabine and Albumin-Bound Paclitaxel Combined With Liposomal Irenotecan (II) With or Without SHR-1701 as Neoadjuvant Therapy for Resectable or Borderline Resectable Pancreatic Cancer
NCT07806110 · ClinicalTrials.gov ↗ · Pancreas Ductal Adenocarcinoma
Phase 2 Active, closed The First Hospital of Jilin University China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Liposomal Irinotecan

23 conditions
Pancreatic Cancer2Metastatic Pancreatic Cancer2Metastatic Pancreatic Adenocarcinoma2Rectal Cancer2Solid Tumor1PDAC1PDAC - Pancreatic Ductal Adenocarcinoma1Osteosarcoma1Osteosarcoma Metastatic1Rectal Cancer, Adenocarcinoma1Malignant Ascites1Advanced Solid Malignancies1
All 23 conditions
Condition (as registered)Trials
Pancreatic Cancer2
Metastatic Pancreatic Cancer2
Metastatic Pancreatic Adenocarcinoma2
Rectal Cancer2
Solid Tumor1
PDAC1
PDAC - Pancreatic Ductal Adenocarcinoma1
Osteosarcoma1
Osteosarcoma Metastatic1
Rectal Cancer, Adenocarcinoma1
Malignant Ascites1
Advanced Solid Malignancies1
Biliary Tract Cancer (BTC)1
ESCC1
Pancreas Ductal Adenocarcinoma1
Rectal Cancer Patients1
Colorectal Cancer1
Pancreatic Ductal Adenocarcinoma (PDAC)1
Metastatic Colorectal Cancer (CRC)1
Liposomal Irinotecan1
Second-Line1
Esophageal Cancer1
Stage IV Pancreatic Cancer AJCC v81
05

Related compounds

06

Questions about Liposomal Irinotecan trials

How many clinical trials are testing Liposomal Irinotecan?

18 current trials in our China, USA, France, Spain, Japan, Germany, South Korea, Taiwan, UK, Poland, Brazil, Israel, Italy, Netherlands and Mexico registers name Liposomal Irinotecan as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Liposomal Irinotecan trials recruiting patients?

Yes. 7 of the 18 trials are recruiting: 7 with sites in China, 2 with sites in USA, 2 with sites in France, 2 with sites in Spain, 2 with sites in Japan, 1 with sites in Germany, 2 with sites in South Korea, 1 with sites in Taiwan, 1 with sites in UK, 1 with sites in Poland, 1 with sites in Brazil and 1 with sites in Israel. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Liposomal Irinotecan clinical trials?

Hebei Medical University Fourth Hospital (3), Astellas Pharma Global Development, Inc (1), Astellas Pharma Inc (1) and Revolution Medicines, Inc (1), among 16 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Liposomal Irinotecan works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Liposomal Irinotecan works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Liposomal Irinotecan (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.