|
Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral Therapy
|
Phase 3 |
Recruiting |
2026-07 |
USA |
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
NCT05633654 · ClinicalTrials.gov ↗ · Triple Negative Breast Cancer
|
Phase 3 |
Recruiting |
2022-12 |
Ireland, UK, USA |
|
A Study to Evaluate the Safety and Antitumor Activity of GS-1206 in Adults With Solid Tumors
|
Phase 1 |
Recruiting |
2026-07 |
USA |
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas
NCT07546812 · HER2-negative, Gastroesophageal Junction, Esophageal Adenocarcinoma
|
Phase 2 |
Recruiting |
2026-08 |
USA |
|
Study of an Injectable Regimen of GS-3242 With Lenacapavir Compared to Biktarvy in People New to HIV-1 Treatment
|
Phase 2/3 |
Recruiting |
2026-07 |
USA |
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
NCT06051617 · ClinicalTrials.gov ↗ · Primary Biliary Cholangitis
|
Phase 3 |
Recruiting |
2023-09 |
UK, USA, China |
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
NCT06801834 · ClinicalTrials.gov ↗ · Extensive Stage Small Cell Lung Cancer (ES-SCLC)
|
Phase 3 |
Recruiting |
2025-04 |
UK, USA, China |
Study of GS-2426 in Participants With Advanced Solid Tumors
NCT07601243 · ClinicalTrials.gov ↗ · Advanced Solid Tumors
|
Phase 1 |
Recruiting |
2026-06 |
USA |
|
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
|
Observational |
Recruiting |
2026-03 |
USA |
Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment
NCT04617522 · ClinicalTrials.gov ↗ · Advanced or Metastatic Solid Tumor, Liver Failure
|
Phase 1 |
Recruiting |
2021-04 |
USA |
|
A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1
|
Phase 2 |
Recruiting |
2026-06 |
USA |
|
Study of Lenacapavir, Teropavimab, and Zinlirvimab in Virologically Suppressed Adults With HIV-1 on Stable Oral Treatment Regimens
|
Phase 3 |
Recruiting |
2026-07 |
USA |
Study of GS-0201 Alone and in Combination in Participants With Advanced Solid Tumors
NCT06167317 · ClinicalTrials.gov ↗ · Advanced Solid Tumors
|
Phase 1 |
Recruiting |
2024-01 |
USA |
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
NCT07096193 · ClinicalTrials.gov ↗ · Chronic Hepatitis Delta
|
Phase 1/2 |
Recruiting |
2025-07 |
USA |
Study of GS-5319 Given Alone or in Combination in Adults With Solid Tumors
NCT07128303 · ClinicalTrials.gov ↗ · Advanced Solid Tumor
|
Phase 1 |
Recruiting |
2025-08 |
USA |
|
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
|
Phase 1 |
Recruiting |
2024-08 |
USA |
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer
NCT07527858 · ClinicalTrials.gov ↗ · Advanced Microsatellite Stable Colorectal Cancer
|
Phase 2 |
Recruiting |
2026-05 |
USA |
A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer
NCT06926920 · ClinicalTrials.gov ↗ · Triple Negative Breast Cancer
|
Phase 1/2 |
Recruiting |
2025-04 |
USA |
Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors
NCT06532565 · ClinicalTrials.gov ↗ · Advanced Solid Tumors
|
Phase 1 |
Recruiting |
2024-07 |
USA |
|
Evaluation of Long-Acting Lenacapavir for the Treatment of HIV-1 in Treatment-experienced Adolescents and Children
|
Phase 2 |
Recruiting |
2025-03 |
USA |
|
Study of GS-0415 and How It Works in People With HIV
|
Phase 1 |
Recruiting |
2026-07 |
USA |
|
Study of Sacituzumab Govitecan in Participants With Metastatic Solid Tumors
|
Phase 2 |
Active, closed |
2019-10 |
USA |
|
Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread
|
Phase 2 |
Active, closed |
2018-08 |
UK, USA |
|
Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)
|
Phase 3 |
Active, closed |
2025-07 |
USA |
|
Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer
|
Phase 3 |
Active, closed |
2022-10 |
UK, USA, China |
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
NCT05382286 · Triple Negative Breast Cancer, PD-L1 Positive
|
Phase 3 |
Active, closed |
2022-07 |
UK, USA |
|
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy
|
Phase 3 |
Active, closed |
2024-03 |
UK, USA |
Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
NCT05382299 · Triple Negative Breast Cancer, PD-L1 Negative
|
Phase 3 |
Active, closed |
2022-07 |
UK, USA, China |
|
Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01
|
Phase 2 |
Active, closed |
2025-02 |
UK, USA, China |
|
Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1
|
Phase 3 |
Active, closed |
2024-10 |
UK, USA |
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection
NCT02932150 · ClinicalTrials.gov ↗ · Chronic Hepatitis B
|
Phase 2 |
Active, closed |
2016-11 |
USA, India |
Study With Various Immunotherapy Treatments in Participants With Lung Cancer
NCT05676931 · ClinicalTrials.gov ↗ · Advanced Non-Small Cell Lung Cancer
|
Phase 2 |
Active, closed |
2023-02 |
UK, USA |
Study to Evaluate the Antiviral Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate Versus Placebo in Pediatric Participants With Chronic Hepatitis B Infection
NCT01651403 · ClinicalTrials.gov ↗ · Chronic Hepatitis B
|
Phase 3 |
Active, closed |
2012-12 |
USA, India |
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06029972 · ClinicalTrials.gov ↗ · Ulcerative Colitis
|
Phase 2 |
Active, closed |
2023-12 |
UK, USA |
|
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen
|
Phase 2/3 |
Active, closed |
2022-08 |
UK, USA |
Study of Novel Treatment Combinations in Patients With Lung Cancer
NCT05633667 · ClinicalTrials.gov ↗ · Lung Cancer, Advanced or Metastatic Non-Small-Cell Lung Cancer, Resectable Non-Small-Cell Lung Cancer
|
Phase 2 |
Active, closed |
2023-03 |
UK, USA |
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy
NCT05840211 · ClinicalTrials.gov ↗ · Locally Advanced or Unresectable Metastatic Breast Cancer, Stage IV Breast Cancer
|
Phase 3 |
Active, closed |
2023-05 |
UK, USA, China |
|
Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Newborns Exposed to HIV
|
Phase 1 |
Active, closed |
2025-08 |
USA |
|
Study of GS-4528 in Adults With Solid Tumors
|
Phase 1 |
Active, closed |
2023-05 |
UK, USA |
Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV
NCT02016924 · ClinicalTrials.gov ↗ · Acquired Immune Deficiency Syndrome (AIDS), HIV Infections
|
Phase 2/3 |
Active, closed |
2014-01 |
UK, USA |
Study of Sacituzumab Govitecan (SG) Versus Docetaxel in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
NCT05089734 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
|
Phase 3 |
Active, closed |
2021-11 |
UK, USA |
Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)
NCT05186974 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
|
Phase 2 |
Active, closed |
2022-05 |
UK, USA |
|
Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Standard of Care in Virologically Suppressed People With HIV-1
|
Phase 3 |
Active, closed |
2024-10 |
UK, USA |
|
Study of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1
|
Phase 2/3 |
Active, closed |
2024-11 |
USA |
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)
NCT06486441 · ClinicalTrials.gov ↗ · Endometrial Cancer
|
Phase 3 |
Active, closed |
2024-08 |
UK, USA, China |
|
Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide Fixed Dose Combination in Adolescents and Children With Human Immunodeficiency Virus-1
|
Phase 2/3 |
Active, closed |
2016-09 |
USA |
Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)
NCT03301506 · ClinicalTrials.gov ↗ · Primary Biliary Cirrhosis
|
Phase 3 |
Active, closed |
2017-12 |
UK, USA |
Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06290934 · ClinicalTrials.gov ↗ · Ulcerative Colitis
|
Phase 2 |
Active, closed |
2024-03 |
UK, USA, China |
Study of Lenacapavir Taken Twice a Year for HIV Pre-Exposure Prophylaxis (PrEP)
NCT06513312 · ClinicalTrials.gov ↗ · Pre-Exposure Prophylaxis of HIV Infection
|
Phase 2 |
Active, closed |
2024-10 |
UK |
Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors
NCT05007782 · ClinicalTrials.gov ↗ · Advanced Solid Tumor
|
Phase 1 |
Active, closed |
2021-08 |
USA |
Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) for Prevention of HIV in People Who Inject Drugs (HPTN 103)
NCT06101342 · ClinicalTrials.gov ↗ · Pre-Exposure Prophylaxis of HIV Infection
|
Phase 2 |
Active, closed |
2023-12 |
USA |
|
A Study of Teropavimab and Zinlirvimab in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection
|
Phase 2 |
Active, closed |
2023-05 |
USA |
|
Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With an Optimized Background Regimen (OBR) in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance
|
Phase 2/3 |
Active, closed |
2019-11 |
USA |
|
Study Evaluating the Safety and Efficacy of Islatravir in Combination With Lenacapavir in Virologically Suppressed People With HIV
|
Phase 2 |
Active, closed |
2021-10 |
USA |
Study of GS-0151 in Participants With Rheumatoid Arthritis
NCT06902519 · ClinicalTrials.gov ↗ · Rheumatoid Arthritis
|
Phase 1 |
Active, closed |
2025-05 |
USA |
|
Study of Sacituzumab Govitecan in Patients With Solid Tumor
|
Phase 2 |
Active, closed |
2021-10 |
China |
Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)
NCT06101329 · ClinicalTrials.gov ↗ · Pre-Exposure Prophylaxis of HIV Infection
|
Phase 2 |
Active, closed |
2023-11 |
USA |
Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection
NCT04925752 · ClinicalTrials.gov ↗ · Pre-Exposure Prophylaxis of HIV Infection
|
Phase 3 |
Active, closed |
2021-06 |
USA |
|
Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors
|
Phase 1 |
Active, closed |
2023-10 |
USA |
|
Study of Oral Weekly Lepetegravir (Formerly GS-1720) and Lenacapavir Pacfosacil (Formerly GS-4182) Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed
|
Phase 2/3 |
Active, closed |
2024-08 |
USA |
Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC)
NCT04639986 · ClinicalTrials.gov ↗ · Metastatic Breast Cancer
|
Phase 3 |
Active, closed |
2020-11 |
China |
Study of Sacituzumab Govitecan in Chinese Patients With Metastatic Triple-negative Breast Cancer Who Received at Least Two Prior Treatments
NCT04454437 · ClinicalTrials.gov ↗ · Metastatic Triple-negative Breast Cancer
|
Phase 2 |
Active, closed |
2020-10 |
China |