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Compound · clinical trials

Palacaparib clinical trials

Also listed in trial records as AZD9574
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our UK, USA and China registers that name Palacaparib as an intervention. Synced 25 Sep 2026
5Current trials
5Recruiting now
1Lead sponsor
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Palacaparib is named as an intervention in 5 current clinical trials in our UK, USA and China registers. 5 are recruiting patients now. All registered phases are Phase 1/2. The lead sponsor is AstraZeneca. The most-studied condition is Metastatic Prostate Cancer.

Trials by status

  • Recruiting5100%

Trials by phase

  • Phase 1/25100%
01

Clinical trials of Palacaparib

5 trials
StudyPhaseStatusLead sponsorRegisters
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
NCT05123482 · Breast Cancer, Biliary Tract Carcinoma, Ovarian Cancer
Phase 1/2 Recruiting AstraZeneca UK, USA, China
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
NCT05417594 · ClinicalTrials.gov ↗ · Advanced Solid Malignancies
Phase 1/2 Recruiting AstraZeneca UK, USA
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
NCT05797168 · ClinicalTrials.gov ↗ · Ovarian Cancer, Lung Adenocarcinoma, Endometrial Cancer
Phase 1/2 Recruiting AstraZeneca UK, USA, China
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
NCT07181161 · Metastatic Prostate Cancer
Phase 1/2 Recruiting AstraZeneca UK, USA, China
Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer
NCT07590934 · ClinicalTrials.gov ↗ · Metastatic Prostate Cancer
Phase 1/2 Recruiting AstraZeneca UK, USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Palacaparib

8 conditions
Metastatic Prostate Cancer2Ovarian Cancer2Endometrial Cancer2Breast Cancer1Biliary Tract Carcinoma1Advanced Solid Malignancies1Lung Adenocarcinoma1Lung Squamous Cell Carcinoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
AstraZeneca5
04

By country register

RegisterTrialsRecruiting
Clinical trials in UK55
Clinical trials in USA55
Clinical trials in China33

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Palacaparib trials

How many clinical trials are testing Palacaparib?

5 current trials in our UK, USA and China registers name Palacaparib (also registered as AZD9574) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Palacaparib trials recruiting patients?

Yes. 5 of the 5 trials are recruiting: 5 with sites in UK, 5 with sites in USA and 3 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Palacaparib clinical trials?

The lead sponsor is AstraZeneca. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Palacaparib works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Palacaparib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Palacaparib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.