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Compound · clinical trials

Ramucirumab clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 17 trials in our USA, China, UK, Ireland and India registers that name Ramucirumab as an intervention. Synced 25 Sep 2026
17Current trials
8Recruiting now
10Lead sponsors
5Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Ramucirumab is named as an intervention in 17 current clinical trials in our USA, China, UK, Ireland and India registers. 8 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is AstraZeneca (4). The most-studied condition is Gastric Adenocarcinoma.

Trials by status

  • Recruiting847%
  • Not yet open16%
  • Active, closed847%

Trials by phase

  • Phase 2635%
  • Phase 3318%
  • Phase 1318%
  • Phase 1/2318%
  • Phase 2/3212%
01

Clinical trials of Ramucirumab

17 trials
StudyPhaseStatusLead sponsorRegisters
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
NCT05999994 · ClinicalTrials.gov ↗ · Neoplasms, Child, Adolescent
Phase 2 Recruiting Eli Lilly and Company UK, USA
A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer
NCT06038578 · ClinicalTrials.gov ↗ · Gastric Adenocarcinoma, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
Phase 2 Recruiting Toray Industries, Inc USA
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
NCT07098338 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Recruiting AstraZeneca USA, China
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas
NCT07546812 · ClinicalTrials.gov ↗ · HER2-negative, Gastroesophageal Junction, Esophageal Adenocarcinoma
Phase 2 Recruiting Gilead Sciences USA
Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
NCT06445972 · ClinicalTrials.gov ↗ · Gastroesophageal Junction, Gastroesophageal Adenocarcinoma, Esophageal Neoplasms
Phase 1/2 Recruiting Merck Sharp & Dohme LLC USA, China
A Platform Study in Non-Small Cell Lung Cancer (NSCLC)
NCT06996782 · ClinicalTrials.gov ↗ · Advanced or Metastatic Non-small Cell Lung Cancer
Phase 1/2 Recruiting AstraZeneca USA, China
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
NCT05365581 · ClinicalTrials.gov ↗ · Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma
Phase 1 Recruiting Astellas Pharma Global Development, Inc. USA, China
A Study of ASP1002 in Adults for Treatment of Solid Tumors
NCT05719558 · Advanced Solid Tumors
Phase 1 Recruiting Astellas Pharma Global Development, Inc. USA
Global, Multicenter Study of AMT-116 Versus Investigator's Choice in Participants With Advanced or Metastatic Non-squamous EGFR-Wildtype Non-Small Cell Lung Cancer (NSCLC) With Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy
NCT07718737 · NSCLC (Advanced Non-small Cell Lung Cancer)
Phase 2/3 Not yet open Multitude Therapeutics Inc. USA
A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY)
NCT02411448 · ClinicalTrials.gov ↗ · Metastatic Non-Small Cell Lung Cancer
Phase 3 Active, closed Eli Lilly and Company UK, USA, China
Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)
NCT04704934 · ClinicalTrials.gov ↗ · Gastric Cancer, Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Phase 3 Active, closed Daiichi Sankyo Ireland, UK, China
AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2
NCT06346392 · ClinicalTrials.gov ↗ · Gastric Cancer, Gastroesophageal Junction Cancer
Phase 3 Active, closed AstraZeneca UK, USA, India, China
A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
NCT05002127 · ClinicalTrials.gov ↗ · Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma
Phase 2/3 Active, closed ALX Oncology Inc. UK, USA, China
A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer
NCT02711553 · ClinicalTrials.gov ↗ · Biliary Tract Cancer, Metastatic Cancer, Advanced Cancer
Phase 2 Active, closed Eli Lilly and Company UK, USA, China
Volrustomig Priming Regimens Exploratory Phase II Platform Study
NCT06448754 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2 Active, closed AstraZeneca USA, China
Safety and Efficacy of HCB101 in Combination With Multiple Agents in Patients With Advanced Solid Tumors
NCT06771622 · ClinicalTrials.gov ↗ · Solid Cancer
Phase 1/2 Active, closed FBD Biologics Limited China
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
NCT03872947 · ClinicalTrials.gov ↗ · Solid Tumor, Colorectal Cancer, Cholangiocarcinoma
Phase 1 Active, closed Toray Industries, Inc USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Ramucirumab

30 conditions
Gastric Adenocarcinoma4Gastroesophageal Junction Adenocarcinoma3Gastric Cancer3Gastroesophageal Junction2Gastric Cancer, Adenocarcinoma1Biliary Tract Cancer1Metastatic Cancer1Advanced Cancer1Metastatic Non-Small Cell Lung Cancer1Neoplasms1Child1Adolescent1
All 30 conditions
Condition (as registered)Trials
Gastric Adenocarcinoma4
Gastroesophageal Junction Adenocarcinoma3
Gastric Cancer3
Gastroesophageal Junction2
Gastric Cancer, Adenocarcinoma1
Biliary Tract Cancer1
Metastatic Cancer1
Advanced Cancer1
Metastatic Non-Small Cell Lung Cancer1
Neoplasms1
Child1
Adolescent1
Gastroesophageal Junction Cancer1
Advanced Solid Tumors1
NSCLC (Advanced Non-small Cell Lung Cancer)1
Gastroesophageal Junction (GEJ) Adenocarcinoma1
Pancreatic Adenocarcinoma1
HER2-negative1
Esophageal Adenocarcinoma1
Gastroesophageal Adenocarcinoma1
Esophageal Neoplasms1
Esophageal Cancer1
Solid Tumor1
Colorectal Cancer1
Cholangiocarcinoma1
Bladder Cancer1
Non-small Cell Lung Cancer1
Non-Small Cell Lung Cancer1
Advanced or Metastatic Non-small Cell Lung Cancer1
Solid Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
AstraZeneca4
Eli Lilly and Company3
Astellas Pharma Global Development, Inc.2
Toray Industries, Inc2
Daiichi Sankyo1
ALX Oncology Inc.1
Multitude Therapeutics Inc.1
Gilead Sciences1
Merck Sharp & Dohme LLC1
FBD Biologics Limited1
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA158
Clinical trials in China114
Clinical trials in UK61
Clinical trials in Ireland10
Clinical trials in India10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Ramucirumab trials

How many clinical trials are testing Ramucirumab?

17 current trials in our USA, China, UK, Ireland and India registers name Ramucirumab as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Ramucirumab trials recruiting patients?

Yes. 8 of the 17 trials are recruiting: 8 with sites in USA, 4 with sites in China and 1 with sites in UK. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Ramucirumab clinical trials?

AstraZeneca (4), Eli Lilly and Company (3), Astellas Pharma Global Development, Inc (2) and Toray Industries, Inc (2), among 10 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Ramucirumab works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Ramucirumab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Ramucirumab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.