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Compound · clinical trials

Evorpacept clinical trials

Also listed in trial records as ALX148
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our USA, UK and China registers that name Evorpacept as an intervention. Synced 25 Sep 2026
5Current trials
2Recruiting now
2Lead sponsors
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Evorpacept is named as an intervention in 5 current clinical trials in our USA, UK and China registers. 2 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is ALX Oncology Inc (4). The most-studied condition is Head and Neck Cancer.

Trials by status

  • Recruiting240%
  • Active, closed360%

Trials by phase

  • Phase 2360%
  • Phase 2/3120%
  • Phase 1/2120%
01

Clinical trials of Evorpacept

5 trials
StudyPhaseStatusLead sponsorRegisters
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
NCT07007559 · ClinicalTrials.gov ↗ · Breast Cancer, Metastatic
Phase 2 Recruiting ALX Oncology Inc. UK, USA
Isatuximab in Combination With Novel Agents in RRMM - Master Protocol
NCT04643002 · ClinicalTrials.gov ↗ · Plasma Cell Myeloma Refractory
Phase 1/2 Recruiting Sanofi USA
A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
NCT05002127 · ClinicalTrials.gov ↗ · Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma
Phase 2/3 Active, closed ALX Oncology Inc. UK, USA, China
Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)
NCT04675294 · ClinicalTrials.gov ↗ · Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Phase 2 Active, closed ALX Oncology Inc. UK, USA
Evorpacept (ALX148) in Combination With Pembrolizumab and Chemotherapy in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)
NCT04675333 · ClinicalTrials.gov ↗ · Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Phase 2 Active, closed ALX Oncology Inc. UK, USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Evorpacept

7 conditions
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
ALX Oncology Inc.4
Sanofi1
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA52
Clinical trials in UK41
Clinical trials in China10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Evorpacept trials

How many clinical trials are testing Evorpacept?

5 current trials in our USA, UK and China registers name Evorpacept (also registered as ALX148) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Evorpacept trials recruiting patients?

Yes. 2 of the 5 trials are recruiting: 2 with sites in USA and 1 with sites in UK. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Evorpacept clinical trials?

ALX Oncology Inc (4) and Sanofi (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Evorpacept works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Evorpacept works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Evorpacept (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.