Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

R-Chop clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 19 trials in our China, Italy, Japan, UK, USA, India, Germany, France, Spain, Belgium, Sweden, Denmark, Poland, Czechia, Turkey, Canada, Brazil, South Korea, Taiwan and Australia registers that name R-Chop as an intervention. Synced 9 Nov 2026
19Current trials
11Recruiting now
13Lead sponsors
20Country registers
At a glance

R-Chop is named as an intervention in 19 current clinical trials in our China, Italy, Japan, UK, USA, India, Germany, France, Spain, Belgium, Sweden, Denmark, Poland, Czechia, Turkey, Canada, Brazil, South Korea, Taiwan and Australia registers. 11 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Sun Yat-sen University (6). The most-studied condition is DLBCL - Diffuse Large B Cell Lymphoma.

Patient leaflets for R-Chop

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting1158%
  • Not yet open526%
  • Active, closed211%
  • By invitation15%

Trials by phase

  • Phase 21158%
  • Phase 1/2526%
  • Phase 3316%
01

Clinical trials of R-Chop

19 trials
StudyPhaseStatusLead sponsorRegisters
A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients
NCT06549595 · Untreated Follicular Lymphoma
Phase 3 Recruiting AstraZeneca UK, USA, India, China, Germany, France, Spain, Italy, Belgium, Sweden, Denmark, Poland, Czechia, Turkey, Canada, Brazil, Japan, South Korea, Taiwan, Australia
A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With Double Expression Diffuse Large B-cell Lymphoma
NCT05933967 · ClinicalTrials.gov ↗ · The First Affiliated Hospital of Nanchang University
Phase 2 Recruiting Shandong Cancer Hospital and Institute China
AZA Combined With RCHOP in P53-mutated DLBCL.
NCT06158399 · ClinicalTrials.gov ↗ · DLBCL - Diffuse Large B Cell Lymphoma, TP53
Phase 2 Recruiting The First Affiliated Hospital of Xiamen University China
Selinexor in Combination With R-CHOP as the First-line Therapy for TP53-mutated DLBCL Patients (Smart Trial)
NCT06517511 · ClinicalTrials.gov ↗ · Diffuse Large B Cell Lymphoma
Phase 2 Recruiting Sun Yat-sen University China
A Study of Trilaciclib Combined With Chemotherapy in the Treatment of Diffuse Large B-Cell Lymphoma Patients
NCT06569485 · ClinicalTrials.gov ↗ · DLBCL
Phase 2 Recruiting Sun Yat-sen University China
Orelabrutinib in Combination with R-CHOP for CD5-positive DLBCL Patients(Rocket Trial)
NCT06647940 · ClinicalTrials.gov ↗ · Diffuse Large B Cell Lymphoma (DLBCL)
Phase 2 Recruiting Sun Yat-sen University China
Chidamide Plus R-CHOP in Newly Diagnosed Double-Expressor Diffuse Large B-Cell Lymphoma With Other Molecular Subtypes
NCT06891157 · ClinicalTrials.gov ↗ · Chidamide, R-CHOP Chemotherapy, DLBCL - Diffuse Large B Cell Lymphoma
Phase 2 Recruiting The First Affiliated Hospital with Nanjing Medical University China
Celecoxib Plus R-CHOP vs R-CHOP in Newly Diagnosed Advanced CD5+ DLBCL
NCT07494565 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma (DLBCL), CD5 Positive
Phase 2 Recruiting Sun Yat-sen University China
Safety and Efficacy of R-CMOP Versus R-CHOP in the Initial Treatment of DLBCL
NCT06760039 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma
Phase 1/2 Recruiting Sun Yat-sen University China
Clinical Trial of TQB2825 Injection Combined Immunochemotherapy in Subjects With Diffuse Large B Cell Lymphoma
NCT06829771 · ClinicalTrials.gov ↗ · Diffuse Large B Cell Lymphoma
Phase 1/2 Recruiting Chia Tai Tianqing Pharmaceutical Group Co., Ltd China
DZD8586 Combination Therapy in Patients With Diffuse Large B-cell Lymphoma (TAI-SHAN12)
NCT07059650 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma
Phase 1/2 Recruiting Dizal Pharmaceuticals China
Molecular Subtype-Guided R-CHOP-MTX±Zanubrutinib Treatment in Newly Diagnosed DLBCL Patients with Central Nervous System Involvement
NCT06594432 · ClinicalTrials.gov ↗ · Diffuse Large B Cell Lymphoma (DLBCL)
Phase 2 Not yet open The First Affiliated Hospital with Nanjing Medical University China
Zanubrutinib, Chidamide, and Rituximab Induction With or Without CHOP Versus R-CHOP in Newly Diagnosed Double-Expressor DLBCL
NCT06890585 · ClinicalTrials.gov ↗ · BTK Inhibitors, Histone Deacetylase Inhibitor, Double Express Diffuse Large B-cell Lymphoma
Phase 2 Not yet open Li Zhiming China
Orelabrutinib Combined With Induction Therapy Followed by Sequential Monotherapy Maintenance in MCD Subtype Diffuse Large B-cell Lymphoma
NCT07677813 · ClinicalTrials.gov ↗ · DLBCL - Diffuse Large B Cell Lymphoma
Phase 2 Not yet open Ou Bai, MD/PHD China
Pirtobrutinib + R-CHOP for Untreated Non-GCB DLBCL
NCT07744737 · ClinicalTrials.gov ↗ · DLBCL - Diffuse Large B Cell Lymphoma, R-CHOP Chemotherapy, Pirtobrutinib
Phase 2 Not yet open Changzhou No.2 People's Hospital China
Lisatoclax Plus R-CHOP or Pola-R-CHP in Untreated DLBCL: A Phase Ib/II Study
NCT07398638 · ClinicalTrials.gov ↗ · Diffuse Large B Cell Lymphoma (DLBCL)
Phase 1/2 Not yet open Sun Yat-sen University China
A Multicenter, Prospective, Randomized, Controlled Study of Decitabine in Combination With R-CHOP for Initial Treatment of EBV+ Diffuse Large B-cell Lymphoma
NCT07348575 · ClinicalTrials.gov ↗ · Lymphoma, Large-Cell, Diffuse
Phase 3 By invitation Second Affiliated Hospital of Nanchang University China
Shortened vs Standard Chemotherapy Combined With Immunotherapy for the Initial Treatment of Patients With High Tumor Burden Follicular Lymphoma
NCT05058404 · ClinicalTrials.gov ↗ · Follicular Lymphoma
Phase 3 Active, closed Fondazione Italiana Linfomi - ETS Italy
To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL)
NCT04661007 · ClinicalTrials.gov ↗ · Non Hodgkins Lymphoma, Diffuse Large B-cell Lymphoma
Phase 1/2 Active, closed Incyte Biosciences Japan GK Japan

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with R-Chop

21 conditions
DLBCL - Diffuse Large B Cell Lymphoma4Diffuse Large B Cell Lymphoma (DLBCL)3R-CHOP Chemotherapy2Diffuse Large B-Cell Lymphoma2Diffuse Large B Cell Lymphoma2Untreated Follicular Lymphoma1TP531Pirtobrutinib1Diffuse Large B-Cell Lymphoma (DLBCL)1CD5 Positive1BTK Inhibitors1Histone Deacetylase Inhibitor1
All 21 conditions
Condition (as registered)Trials
DLBCL - Diffuse Large B Cell Lymphoma4
Diffuse Large B Cell Lymphoma (DLBCL)3
R-CHOP Chemotherapy2
Diffuse Large B-Cell Lymphoma2
Diffuse Large B Cell Lymphoma2
Untreated Follicular Lymphoma1
TP531
Pirtobrutinib1
Diffuse Large B-Cell Lymphoma (DLBCL)1
CD5 Positive1
BTK Inhibitors1
Histone Deacetylase Inhibitor1
Double Express Diffuse Large B-cell Lymphoma1
Lymphoma, Large-Cell, Diffuse1
Chidamide1
Double-expressor Lymphoma (DEL)1
The First Affiliated Hospital of Nanchang University1
DLBCL1
Follicular Lymphoma1
Non Hodgkins Lymphoma1
Diffuse Large B-cell Lymphoma1
05

Related compounds

06

Questions about R-Chop trials

How many clinical trials are testing R-Chop?

19 current trials in our China, Italy, Japan, UK, USA, India, Germany, France, Spain, Belgium, Sweden, Denmark, Poland, Czechia, Turkey, Canada, Brazil, South Korea, Taiwan and Australia registers name R-Chop as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are R-Chop trials recruiting patients?

Yes. 11 of the 19 trials are recruiting: 11 with sites in China, 1 with sites in Italy, 1 with sites in Japan, 1 with sites in UK, 1 with sites in USA, 1 with sites in India, 1 with sites in Germany, 1 with sites in France, 1 with sites in Spain, 1 with sites in Belgium, 1 with sites in Sweden, 1 with sites in Denmark, 1 with sites in Poland, 1 with sites in Czechia, 1 with sites in Turkey, 1 with sites in Canada, 1 with sites in Brazil, 1 with sites in South Korea, 1 with sites in Taiwan and 1 with sites in Australia. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors R-Chop clinical trials?

Sun Yat-sen University (6), The First Affiliated Hospital with Nanjing Medical University (2), AstraZeneca (1) and Ou Bai, MD/PHD (1), among 13 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how R-Chop works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how R-Chop works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists R-Chop (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.