Polatuzumab Vedotin is named as an intervention in 18 current clinical trials in our China, USA, UK and Ireland registers. 4 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Hoffmann-La Roche (5). The most-studied condition is Non-Hodgkin Lymphoma.
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Non-Hodgkin Lymphoma | 2 |
| Large B-Cell Lymphoma (LBCL) | 2 |
| DLBCL - Diffuse Large B Cell Lymphoma | 2 |
| Diffuse Large B-Cell Lymphoma | 2 |
| Lymphoma, Large B-Cell, Diffuse | 1 |
| Large B-Cell Lymphoma | 1 |
| Non-Hodgkins Lymphoma | 1 |
| B-cell Non-Hodgkin Lymphoma | 1 |
| B-Cell Non-Hodgkin Lymphoma | 1 |
| Relapsed B-Cell Non-Hodgkin Lymphoma | 1 |
| Refractory B-Cell Non-Hodgkin Lymphoma | 1 |
| Lymphoma, B-Cell | 1 |
| Relapsed and Refractory DLBCL | 1 |
| Chemo-free Therapy | 1 |
| Bispecific Antibody | 1 |
| Large B-cell Lymphoma | 1 |
| Diffuse Large B-Cell Lymphoma (DLBCL) | 1 |
| Effects of Chemotherapy | 1 |
| Safety Issues | 1 |
| Lead sponsor | Trials |
|---|---|
| Hoffmann-La Roche | 5 |
| Ruijin Hospital | 5 |
| Merck Sharp & Dohme LLC | 1 |
| ADC Therapeutics S.A. | 1 |
| Genmab | 1 |
| Celgene | 1 |
| Li Zhiming | 1 |
| Tianjin Medical University Cancer Institute and Hospital | 1 |
| Institute of Hematology & Blood Diseases Hospital, China | 1 |
| The First Affiliated Hospital of Soochow University | 1 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in China | 13 | 3 |
| Clinical trials in USA | 7 | 1 |
| Clinical trials in UK | 5 | 1 |
| Clinical trials in Ireland | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
18 current trials in our China, USA, UK and Ireland registers name Polatuzumab Vedotin as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.
Yes. 4 of the 18 trials are recruiting: 3 with sites in China, 1 with sites in USA, 1 with sites in UK and 1 with sites in Ireland. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Hoffmann-La Roche (5), Ruijin Hospital (5), Merck Sharp & Dohme LLC (1) and ADC Therapeutics S.A (1), among 10 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Polatuzumab Vedotin works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Polatuzumab Vedotin works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Polatuzumab Vedotin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.