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Compound · clinical trials

Anastrozole clinical trials

Also listed in trial records as Anastrozol
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 27 trials in our USA, China, UK, India and Ireland registers that name Anastrozole as an intervention. Synced 25 Sep 2026
27Current trials
11Recruiting now
13Lead sponsors
5Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Anastrozole is named as an intervention in 27 current clinical trials in our USA, China, UK, India and Ireland registers. 11 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Eli Lilly and Company (7). The most-studied condition is Breast Cancer.

Trials by status

  • Recruiting1141%
  • Active, closed1556%
  • By invitation14%

Trials by phase

  • Phase 32074%
  • Phase 1311%
  • Phase 1/214%
  • Phase 414%
  • Phase 214%
  • Not applicable14%
01

Clinical trials of Anastrozole

27 trials
StudyPhaseStatusLead sponsorRegisters
Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)
NCT05512364 · ClinicalTrials.gov ↗ · ER-positive Breast Cancer, HER2-negative Breast Cancer, Stage IIB Breast Cancer
Phase 3 Recruiting European Organisation for Research and Treatment of Cancer - EORTC Ireland
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
NCT05774951 · ClinicalTrials.gov ↗ · Breast Cancer, Early Breast Cancer
Phase 3 Recruiting AstraZeneca UK, USA, India, China
Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01)
NCT05891093 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Recruiting Fudan University China
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
NCT06072781 · ClinicalTrials.gov ↗ · Low Grade Serous Ovarian Cancer
Phase 3 Recruiting Verastem, Inc. Ireland, UK, USA
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
NCT06380751 · ClinicalTrials.gov ↗ · Advanced Breast Cancer
Phase 3 Recruiting AstraZeneca UK, USA, India, China
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT06492616 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Recruiting Stemline Therapeutics, Inc. UK, USA, China
A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer
NCT07024173 · ClinicalTrials.gov ↗ · Locally Advanced Breast Cancer, Metastatic Breast Cancer
Phase 3 Recruiting Shandong Suncadia Medicine Co., Ltd. China
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
NCT07174336 · Breast Neoplasms, Neoplasm Metastasis
Phase 3 Recruiting Eli Lilly and Company Ireland, UK, USA, China
A Phase III Trial Comparing HRS-8080 With Standard Endocrine Therapy in Patients With Intermediate or High Risk Early Breast Cancer
NCT07349069 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Recruiting Shandong Suncadia Medicine Co., Ltd. China
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
NCT05768139 · ClinicalTrials.gov ↗ · Breast Cancer, Solid Tumors, Adult
Phase 1/2 Recruiting Eli Lilly and Company Ireland, USA
A Study of Chidamide Plus Endocrine in Maintenance Treatment of HR+/HER2- Breast Cancer After First-line Chemotherapy
NCT05890287 · ClinicalTrials.gov ↗ · HR Positive HER2 Negative Advanced Breast Cancer
Not applicable Recruiting Tianjin Medical University Cancer Institute and Hospital China
Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Study
NCT05645536 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 By invitation Tolmar Inc. USA, India
Roll-over Study to Allow Continued Access to Ribociclib
NCT05161195 · Metastatic Breast Cancer
Phase 4 Active, closed Novartis Pharmaceuticals USA, India, China
Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
NCT00310180 · ClinicalTrials.gov ↗ · Breast Adenocarcinoma, Hormone Receptor Positive, Stage IA Breast Cancer AJCC v7
Phase 3 Active, closed National Cancer Institute (NCI) Ireland
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
NCT01272037 · Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma, Multicentric Breast Carcinoma
Phase 3 Active, closed National Cancer Institute (NCI) Ireland
A Study of Nonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast Cancer
NCT02246621 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Active, closed Eli Lilly and Company UK, USA
A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer
NCT02763566 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Active, closed Eli Lilly and Company India, China
A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease
NCT04711252 · ClinicalTrials.gov ↗ · ER-Positive HER2-Negative Breast Cancer
Phase 3 Active, closed AstraZeneca UK, USA, India, China
Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer
NCT04906395 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Active, closed Tolmar Inc. USA, India
Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)
NCT04964934 · ClinicalTrials.gov ↗ · ER-Positive HER2-Negative Breast Cancer
Phase 3 Active, closed AstraZeneca UK, USA
A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
NCT05514054 · Breast Neoplasms
Phase 3 Active, closed Eli Lilly and Company Ireland, UK, USA, India, China
An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
NCT05952557 · Breast Cancer, Early Breast Cancer
Phase 3 Active, closed AstraZeneca Ireland, UK, USA, India, China
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
NCT06016738 · ClinicalTrials.gov ↗ · Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer
Phase 3 Active, closed Olema Pharmaceuticals, Inc. UK, USA
Sirolimus for Injection (Albumin-bound) in Combination With Endocrine Therapy for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Who Have Failed Standard Therapy
NCT06957379 · ClinicalTrials.gov ↗ · HR+/HER2- Advanced/Metastatic Breast Cancer
Phase 2 Active, closed CSPC ZhongQi Pharmaceutical Technology Co., Ltd. China
A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread
NCT02057133 · ClinicalTrials.gov ↗ · Breast Neoplasms
Phase 1 Active, closed Eli Lilly and Company USA
A Study of Abemaciclib (LY2835219) in Participants With Non-Small Cell Lung Cancer or Breast Cancer
NCT02779751 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer, Breast Cancer
Phase 1 Active, closed Eli Lilly and Company USA
A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer
NCT04556773 · ClinicalTrials.gov ↗ · Metastatic Breast Cancer
Phase 1 Active, closed AstraZeneca USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Anastrozole

26 conditions
Breast Cancer10Metastatic Breast Cancer4Breast Neoplasms3Breast Cancer, Early Breast Cancer2ER-Positive HER2-Negative Breast Cancer2Advanced Breast Cancer2Breast Ductal Carcinoma In Situ1Invasive Breast Carcinoma1Multicentric Breast Carcinoma1Multifocal Breast Carcinoma1Neoplasm Metastasis1ER-positive Breast Cancer1
All 26 conditions
Condition (as registered)Trials
Breast Cancer10
Metastatic Breast Cancer4
Breast Neoplasms3
Breast Cancer, Early Breast Cancer2
ER-Positive HER2-Negative Breast Cancer2
Advanced Breast Cancer2
Breast Ductal Carcinoma In Situ1
Invasive Breast Carcinoma1
Multicentric Breast Carcinoma1
Multifocal Breast Carcinoma1
Neoplasm Metastasis1
ER-positive Breast Cancer1
HER2-negative Breast Cancer1
Stage IIB Breast Cancer1
Stage III Breast Cancer1
Breast Adenocarcinoma1
Hormone Receptor Positive1
Stage IA Breast Cancer AJCC v71
Stage IB Breast Cancer AJCC v71
Low Grade Serous Ovarian Cancer1
Solid Tumors, Adult1
ER Positive Breast Cancer1
Non Small Cell Lung Cancer1
HR+/HER2- Advanced/Metastatic Breast Cancer1
HR Positive HER2 Negative Advanced Breast Cancer1
Locally Advanced Breast Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Eli Lilly and Company7
AstraZeneca6
National Cancer Institute (NCI)2
Tolmar Inc.2
Shandong Suncadia Medicine Co., Ltd.2
European Organisation for Research and Treatment of Cancer - EORTC1
Verastem, Inc.1
Stemline Therapeutics, Inc.1
Olema Pharmaceuticals, Inc.1
Novartis Pharmaceuticals1
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.1
Fudan University1
Tianjin Medical University Cancer Institute and Hospital1
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA186
Clinical trials in China148
Clinical trials in UK115
Clinical trials in India92
Clinical trials in Ireland84

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Anastrozole trials

How many clinical trials are testing Anastrozole?

27 current trials in our USA, China, UK, India and Ireland registers name Anastrozole as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Anastrozole trials recruiting patients?

Yes. 11 of the 27 trials are recruiting: 6 with sites in USA, 8 with sites in China, 5 with sites in UK, 2 with sites in India and 4 with sites in Ireland. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Anastrozole clinical trials?

Eli Lilly and Company (7), AstraZeneca (6), National Cancer Institute (NCI) (2) and Tolmar Inc (2), among 13 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Anastrozole works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Anastrozole works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Anastrozole (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.