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Compound · clinical trials

Tezepelumab clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 8 trials in our China, USA, UK and India registers that name Tezepelumab as an intervention. Synced 25 Sep 2026
8Current trials
6Recruiting now
2Lead sponsors
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Tezepelumab is named as an intervention in 8 current clinical trials in our China, USA, UK and India registers. 6 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is AstraZeneca (7). The most-studied condition is Chronic Obstructive Pulmonary Disease (COPD).

Tezepelumab also has an approved-drug profile on this site (FDA label data): Tezspire (Tezepelumab) →

Trials by status

  • Recruiting675%
  • Not yet open113%
  • Active, closed113%

Trials by phase

  • Phase 3675%
  • Observational113%
  • Not applicable113%
01

Clinical trials of Tezepelumab

8 trials
StudyPhaseStatusLead sponsorRegisters
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
NCT06023589 · ClinicalTrials.gov ↗ · Asthma
Phase 3 Recruiting AstraZeneca UK, USA, China
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
NCT06878261 · ClinicalTrials.gov ↗ · Chronic Obstructive Pulmonary Disease (COPD)
Phase 3 Recruiting AstraZeneca USA
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
NCT06883305 · ClinicalTrials.gov ↗ · Chronic Obstructive Pulmonary Disease (COPD)
Phase 3 Recruiting AstraZeneca UK, USA, India, China
Phase 3b Study in Patients With Severe Asthma Treated With Tezepelumab
NCT07363642 · ClinicalTrials.gov ↗ · Severe Asthma
Phase 3 Recruiting AstraZeneca China
A Study to Investigate NPS and Symptoms in Chinese Adult Participants With CRSwNP Initiating Treatment With Tezepelumab
NCT07520162 · ClinicalTrials.gov ↗ · Chronic Rhinosinusitis With Nasal Polyps
Phase 3 Recruiting AstraZeneca China
Tezspire Cardiac Events PASS
NCT06951867 · ClinicalTrials.gov ↗ · Cardiovascular Events, MACE
Observational Recruiting AstraZeneca USA
Real-World Effectiveness of Tezepelumab in Allergic Bronchopulmonary Aspergillosis
NCT07757841 · ClinicalTrials.gov ↗ · Allergic Bronchopulmonary Aspergillosis, Severe Asthma, ABPA
Not applicable Not yet open Qianfoshan Hospital China
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
NCT05583227 · ClinicalTrials.gov ↗ · Eosinophilic Esophagitis
Phase 3 Active, closed AstraZeneca UK, USA, China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Tezepelumab across our data

Ireland · EU · US

The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.

Licensed in Ireland (HPRA)

1 single-substance product containing Tezepelumab on the HPRA medicines list.

All 1 Irish product →

Supply shortages

No entry for Tezepelumab in the EMA, FDA or German BfArM shortage lists we track.

03

Conditions studied with Tezepelumab

9 conditions
Chronic Obstructive Pulmonary Disease (COPD)2Severe Asthma2Eosinophilic Esophagitis1Asthma1Cardiovascular Events1MACE1Allergic Bronchopulmonary Aspergillosis1ABPA1Chronic Rhinosinusitis With Nasal Polyps1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
AstraZeneca7
Qianfoshan Hospital1
05

By country register

RegisterTrialsRecruiting
Clinical trials in China64
Clinical trials in USA54
Clinical trials in UK32
Clinical trials in India11

A trial with sites in more than one country appears in each of those registers.

06

Related compounds

07

Questions about Tezepelumab trials

How many clinical trials are testing Tezepelumab?

8 current trials in our China, USA, UK and India registers name Tezepelumab as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Tezepelumab trials recruiting patients?

Yes. 6 of the 8 trials are recruiting: 4 with sites in China, 4 with sites in USA, 2 with sites in UK and 1 with sites in India. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Tezepelumab clinical trials?

AstraZeneca (7) and Qianfoshan Hospital (1). The number in brackets is how many trials each organisation leads.

Is Tezepelumab licensed in Ireland?

Yes. The HPRA medicines list includes 1 single-substance product containing Tezepelumab, for example Tezspire 210 mg solution for injection in pre-filled syringe (AstraZeneca AB). A licence does not mean a product is currently marketed or reimbursed; see each product's record.

Is there a Tezepelumab shortage?

Not in the lists we track: Tezepelumab has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Tezepelumab works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Tezepelumab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Tezepelumab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.