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Priya Life Science Compound trial record
Compound · clinical trials

Tagrisso clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 28 trials in our China, South Korea, USA, Spain, Taiwan, Israel, Italy, UK, Germany, Japan, France, Poland, Turkey, Canada, Brazil, Singapore, Belgium, Switzerland, Australia, India, Mexico, Austria, Netherlands, Sweden, Denmark and Norway registers that name Tagrisso as an intervention. Synced 9 Nov 2026
28Current trials
12Recruiting now
17Lead sponsors
26Country registers
At a glance

Tagrisso is named as an intervention in 28 current clinical trials in our China, South Korea, USA, Spain, Taiwan, Israel, Italy, UK, Germany, Japan, France, Poland, Turkey, Canada, Brazil, Singapore, Belgium, Switzerland, Australia, India, Mexico, Austria, Netherlands, Sweden, Denmark and Norway registers. 12 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is AstraZeneca (9). The most-studied condition is Non-Small Cell Lung Cancer.

Patient leaflets for Tagrisso

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting1243%
  • Active, closed1657%

Trials by phase

  • Phase 21450%
  • Phase 3621%
  • Phase 1/2518%
  • Phase 114%
  • Observational14%
  • Not applicable14%
01

Clinical trials of Tagrisso

28 trials
StudyPhaseStatusLead sponsorRegisters
Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO)
NCT05382728 · ClinicalTrials.gov ↗ · NSCLC, EGFR Activating Mutation
Phase 3 Recruiting TYK Medicines, Inc China
Neoadjuvant Osimertinib + Chemotherapy for EGFR-mutant Stage III NSCLC
NCT05011487 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Recruiting Sun Yat-sen University China
Additional Chemotherapy for EGFRm Patients with the Continued Presence of Plasma CtDNA EGFRm At Week 3 After Start of Osimertinib 1st-line Treatment (PACE-LUNG)
NCT05281406 · ClinicalTrials.gov ↗ · NSCLC Stage IIIB, NSCLC Stage IV
Phase 2 Recruiting Goethe University Germany
Osimertinib to Suppress the Progression of Remaining GGN for EGFR Mutation-positive Stage IB-IIIA Lung Adenocarcinoma
NCT05528458 · ClinicalTrials.gov ↗ · Lung Adenocarcinoma
Phase 2 Recruiting Samsung Medical Center South Korea
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
NCT05642572 · ClinicalTrials.gov ↗ · Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Phase 2 Recruiting SWOG Cancer Research Network Mexico
Osimertinib Therapy After Resection in High-risk Stage I EGFRm NSCLC (OSTAR)
NCT05686434 · ClinicalTrials.gov ↗ · NSCLC, Stage I
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases
NCT05948813 · ClinicalTrials.gov ↗ · NSCLC, EGFR Activating Mutation, Brain Metastases
Phase 2 Recruiting TYK Medicines, Inc China
Neo-Bio-ADAURA: a Phase II Study to Evaluate Mechanisms of Resistance to Neoadjuvant Osimertinib
NCT06206850 · ClinicalTrials.gov ↗ · Non-squamous NSCLC
Phase 2 Recruiting Jair Bar, M.D., Ph.D Israel
Neoadjuvant Targeted Therapy in Patients With Resectable EGFR-mutated Lung Squamous Cell Carcinoma
NCT06383728 · ClinicalTrials.gov ↗ · Lung Cancer, Carcinoma, Squamous Cell
Phase 2 Recruiting The First Affiliated Hospital of Guangzhou Medical University China
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
NCT04486833 · Carcinoma, Non-Small Cell Lung
Phase 1/2 Recruiting Genprex, Inc USA
A Phase Ib/II Clinical Study of GH21 Capsules Combined With Osimertinib Mesylate Tablets in Patients With NSCLC
NCT06306456 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer With EGFR Mutation
Phase 1/2 Recruiting Suzhou Genhouse Bio Co., Ltd China
A Study to Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLC
NCT07206498 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer (NSCLC)
Phase 1/2 Recruiting Wayshine Biopharm, Inc China
A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer
NCT04351555 · Non-Small Cell Lung Cancer
Phase 3 Active, closed AstraZeneca UK, USA, India, China, Germany, France, Spain, Italy, Poland, Switzerland, Austria, Turkey, Canada, Brazil, Mexico, Japan, South Korea, Taiwan, Israel
A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection
NCT05120349 · Non-Small Cell Lung Cancer
Phase 3 Active, closed AstraZeneca UK, USA, China, Germany, Spain, Italy, Poland, Turkey, Canada, Brazil, Japan, South Korea, Taiwan, Singapore
Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment
NCT05261399 · Carcinoma, Non-Small-Cell Lung
Phase 3 Active, closed AstraZeneca UK, USA, China, Germany, France, Spain, Italy, Belgium, Poland, Switzerland, Turkey, Canada, Brazil, Japan, South Korea, Taiwan, Singapore, Australia, Israel
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Osimertinib (TAGRISSO) (ROSY-T)
NCT05629234 · Cancer
Phase 3 Active, closed AstraZeneca UK, China, France, Poland, Japan, South Korea, Taiwan
A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT06417814 · Metastatic Non-small Cell Lung Cancer
Phase 3 Active, closed AstraZeneca UK, USA, India, China, Germany, France, Spain, Italy, Belgium, Poland, Canada, Brazil, Japan, South Korea, Taiwan, Singapore, Australia, Israel
A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer
NCT03392246 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2 Active, closed Dana-Farber Cancer Institute Israel
Osimertinib In EGFR Mutant Lung Cancer
NCT03586453 · ClinicalTrials.gov ↗ · Carcinoma, Non-Small-Cell Lung
Phase 2 Active, closed Dana-Farber Cancer Institute Israel
Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)
NCT03944772 · Non-Small Cell Lung Cancer
Phase 2 Active, closed AstraZeneca USA, Spain, Italy, Netherlands, Sweden, Denmark, Norway, Japan, South Korea
Radiation During Osimertinib Treatment: a Safety and Efficacy Cohort Study
NCT05089916 · ClinicalTrials.gov ↗ · NSCLC, EGFR Positive Non-small Cell Lung Cancer, Oligoprogression
Phase 2 Active, closed AIO-Studien-gGmbH Germany
A Study of 5 Years of Adjuvant Osimertinib in Completely Resected Epidermal Growth Factor Receptor Mutation (EGFRm) Non-small Cell Lung Carcinoma (NSCLC)
NCT05526755 · Stage II-IIIB Non-small Cell Lung Carcinoma
Phase 2 Active, closed AstraZeneca UK, USA, Spain, Italy, South Korea, Taiwan, Singapore
To Evaluate the Efficacy/Safety of Osimertinib Prior to CRT and Maintenance of it With Stage III, Unresectable NSCLC With EGFR Mutations
NCT06194448 · Lung Cancer
Phase 2 Active, closed AstraZeneca USA, China, Spain, Turkey, South Korea, Taiwan, Israel
Osimertinib and Gefitinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer
NCT03122717 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 1/2 Active, closed Dana-Farber Cancer Institute Israel
Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study
NCT03381274 · Carcinoma, Non-Small-Cell Lung
Phase 1/2 Active, closed MedImmune LLC USA, South Korea, Taiwan
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
NCT06507306 · ClinicalTrials.gov ↗ · Solid Tumor, Adult
Phase 1 Active, closed Kumquat Biosciences Inc USA, France, Spain, Italy
Prospective Cohort of Locally Advanced and Metastatic Non-Small Cell Lung Cancer Patients With Activating EGFR Mutations
NCT05103605 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Observational Active, closed AstraZeneca France
Whole Genomic Landscape of Advanced EGFR-mutant NSCLC
NCT03969823 · ClinicalTrials.gov ↗ · Locally Advanced or Metastatic NSCLC
Not applicable Active, closed Seoul National University Hospital South Korea

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Tagrisso

28 conditions
All 28 conditions
Condition (as registered)Trials
Non-Small Cell Lung Cancer5
NSCLC3
Lung Cancer2
Carcinoma, Non-Small-Cell Lung2
EGFR Activating Mutation2
Stage II-IIIB Non-small Cell Lung Carcinoma1
Cancer1
Carcinoma1
Non-Small-Cell Lung1
Metastatic Non-small Cell Lung Cancer1
Carcinoma, Non-Small Cell Lung1
Solid Tumor, Adult1
Carcinoma, Squamous Cell1
Brain Metastases1
Non-Small Cell Lung Cancer With EGFR Mutation1
Non Small Cell Lung Cancer (NSCLC)1
NSCLC, Stage I1
NSCLC Stage IIIB1
NSCLC Stage IV1
EGFR Positive Non-small Cell Lung Cancer1
Oligoprogression1
Non Small Cell Lung Cancer1
Recurrent Lung Non-Small Cell Carcinoma1
Stage IV Lung Cancer AJCC v81
Lung Adenocarcinoma1
Locally Advanced or Metastatic NSCLC1
Non-squamous NSCLC1
Non-small Cell Lung Cancer1
05

Related compounds

06

Questions about Tagrisso trials

How many clinical trials are testing Tagrisso?

28 current trials in our China, South Korea, USA, Spain, Taiwan, Israel, Italy, UK, Germany, Japan, France, Poland, Turkey, Canada, Brazil, Singapore, Belgium, Switzerland, Australia, India, Mexico, Austria, Netherlands, Sweden, Denmark and Norway registers name Tagrisso as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Tagrisso trials recruiting patients?

Yes. 12 of the 28 trials are recruiting: 7 with sites in China, 1 with sites in South Korea, 1 with sites in USA, 1 with sites in Israel, 1 with sites in Germany and 1 with sites in Mexico. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Tagrisso clinical trials?

AstraZeneca (9), Dana-Farber Cancer Institute (3), TYK Medicines, Inc (2) and Genprex, Inc (1), among 17 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Tagrisso works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Tagrisso works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Tagrisso (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.