Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

Cilta-cel clinical trials

Also listed in trial records as JNJ-68284528, LCAR-B38M CAR-T cells
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 8 trials in our USA, Spain, Australia, Germany, France, Netherlands, Belgium, Israel, Japan, Sweden, UK, Denmark, Poland, Switzerland, Czechia, Norway, Canada, Brazil, South Korea, Ireland, Austria, Portugal, Italy and China registers that name Cilta-cel as an intervention. Synced 10 Nov 2026
8Current trials
2Recruiting now
2Lead sponsors
24Country registers
At a glance

Cilta-cel is named as an intervention in 8 current clinical trials in our USA, Spain, Australia, Germany, France, Netherlands, Belgium, Israel, Japan, Sweden, UK, Denmark, Poland, Switzerland, Czechia, Norway, Canada, Brazil, South Korea, Ireland, Austria, Portugal, Italy and China registers. 2 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Janssen Research & Development, LLC (7). The most-studied condition is Multiple Myeloma.

Patient leaflets for Cilta-cel

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting225%
  • Active, closed675%

Trials by phase

  • Phase 2450%
  • Phase 3338%
  • Phase 4113%
01

Clinical trials of Cilta-cel

8 trials
StudyPhaseStatusLead sponsorRegisters
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
NCT05201781 · Multiple Myeloma
Phase 4 Recruiting Janssen Research & Development, LLC USA, China, France, Spain, Netherlands, Belgium, Japan, Israel
A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel
NCT07149857 · Multiple Myeloma
Phase 2 Recruiting Janssen Research & Development, LLC USA, Spain, Australia
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
NCT04181827 · Multiple Myeloma
Phase 3 Active, closed Janssen Research & Development, LLC UK, USA, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Denmark, Poland, Japan, South Korea, Australia, Israel
A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy
NCT04923893 · Multiple Myeloma
Phase 3 Active, closed Janssen Research & Development, LLC Ireland, UK, USA, Germany, France, Spain, Netherlands, Belgium, Sweden, Denmark, Poland, Switzerland, Austria, Czechia, Norway, Portugal, Canada, Brazil, Japan, South Korea, Australia, Israel
A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma
NCT05257083 · Multiple Myeloma
Phase 3 Active, closed Stichting European Myeloma Network Germany, France, Spain, Netherlands, Belgium, Sweden, Switzerland, Czechia, Norway, Canada, Japan, Australia, Israel
A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma
NCT04133636 · Multiple Myeloma
Phase 2 Active, closed Janssen Research & Development, LLC USA, Germany, France, Spain, Netherlands, Belgium, Israel
A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma
NCT06550895 · ClinicalTrials.gov ↗ · Multiple Myeloma
Phase 2 Active, closed Janssen Research & Development, LLC USA, Australia
A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma
NCT06577025 · Multiple Myeloma
Phase 2 Active, closed Janssen Research & Development, LLC USA, Germany, Spain, Brazil, Australia

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Cilta-cel

1 condition
05

Related compounds

06

Questions about Cilta-cel trials

How many clinical trials are testing Cilta-cel?

8 current trials in our USA, Spain, Australia, Germany, France, Netherlands, Belgium, Israel, Japan, Sweden, UK, Denmark, Poland, Switzerland, Czechia, Norway, Canada, Brazil, South Korea, Ireland, Austria, Portugal, Italy and China registers name Cilta-cel (also registered as JNJ-68284528) as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.

Are Cilta-cel trials recruiting patients?

Yes. 2 of the 8 trials are recruiting: 2 with sites in USA, 2 with sites in Spain, 1 with sites in Australia, 1 with sites in France, 1 with sites in Netherlands, 1 with sites in Belgium, 1 with sites in Israel, 1 with sites in Japan and 1 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Cilta-cel clinical trials?

Janssen Research & Development, LLC (7) and Stichting European Myeloma Network (1). The number in brackets is how many trials each organisation leads.

Are there Cilta-cel clinical trials in Ireland?

Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Cilta-cel works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Cilta-cel works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Cilta-cel (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.