Acute Kidney InjuryCardiac Surgery Associated - Acute Kidney Injury
Study summary
The goal of this prospective observational study is to find out whether the protein vascular endothelial growth factor (VEGF) measured in blood and urine can predict which patients will develop acute kidney injury (AKI) after heart-type surgery that uses a heart-lung machine (cardiopulmonary bypass).
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
1. Age ≥ 18 years
2. Elective cardiac surgery using cardiopulmonary bypass
3. Written informed consent
Exclusion Criteria:
1. Pre-existing chronic kidney disease with an eGFR \<20 ml/min/1,73m2
2. Usage of VEGF-inhibitors
3. Patients with pre-existing AKI within the last 30 days
4. Patients undergoing one of the following surgeries:
1. Emergency surgery
2. LVAD-implantation
5. Patients after cardiac arrest requiring cardiopulmonary resuscitation within the last 6 months
6. Patients on vasopressors, inotropes or mechanical circulatory support before surgery
Primary outcome measure(s)
Association of vascular endothelial growth factor (VEGF) levels with postoperative acute kidney injury — From baseline to postoperative day 3
Trial sites (1)
Facility
City
Region
Status
University Muenster, University Hospital Muenster, Department of Anesthesiology, Intensive Care and Pain Medicineperative
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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