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Trackers› Clinical trials› Heart Failure
Clinical trial register · Germany

Heart Failure Trials in Germany, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5062 matching records held by the registry are in this view. Synced 10 Nov 2026, 03:18 UTC
5062
Studies in scope
all four open statuses
2869
Recruiting now
open to new participants
983
Lead sponsors
across recruiting studies
Top sites
Berlin 23 Dresden 15 Cologne 11 Hamburg 11 Bad Oeynhausen 10
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Novo Nordisk A/S5 AstraZeneca3 Biotronik SE & Co. KG3 LMU Klinikum3 Boehringer Ingelheim2 University Medical Center Goettingen2 Corvia Medical2 Deutsches Herzzentrum Muenchen2 University Medical Center Groningen2 Abbott Medical Devices2 Johann Wolfgang Goethe University Hospital2 Heinrich-Heine University, Duesseldorf2 Edwards Lifesciences2 Carmat SAS1 Herzzentrum Bremen1 PD Dr. Guram Imnadze1 Vectorious Medical Technologies Ltd.1 Charite University, Berlin, Germany1 EBR Systems, Inc.1 IHF GmbH - Institut für Herzinfarktforschung1 Medtronic1 Cytokinetics1 Boston Scientific Corporation1 Noah Labs1 Karlsburg Hospital1 Berlin Heart GmbH1 Alleviant Medical, Inc.1 Zoll Medical Corporation1 Merck Sharp & Dohme LLC1 CVRx, Inc.1 V-Wave Ltd1 Johannes Gutenberg University Mainz1 Universitaire Ziekenhuizen KU Leuven1 Abiomed Inc.1 Universitat Internacional de Catalunya1 Insel Gruppe AG, University Hospital Bern1 Universitätsklinikum Hamburg-Eppendorf1 P+F Products + Features GmbH1 University Hospital, Geneva1 MicroPort CRM1 Echosens1 Heart and Diabetes Center North-Rhine Westfalia1 Technical University of Munich1 Occlutech International AB1 RWTH Aachen University1 Colorado Prevention Center1 Stephan Baldus1 University of Giessen1 Hannover Medical School1 University Hospital Freiburg1
Site location
Berlin23 Dresden15 Cologne11 Hamburg11 Bad Oeynhausen10 Heidelberg8 Leipzig7 Aachen7 Erfurt6 Bad Nauheim6 Düsseldorf6 Munich6 Hanover6 Freiburg im Breisgau5 München5 Mainz5 Bad Friedrichshall4 Coburg4 Frankfurt4 Erlangen4 Essen4 Giessen4 Frankfurt am Main4 Bamberg3 Bonn3 Göttingen3 Bremen3 Halle3 Würzburg3 Jena3 Lübeck3 Kiel3 Bad Krozingen2 Heilbronn2 Bernau2 Bielefeld2 Bechhofen2 Chemnitz2 Detmold2 Rostock2 Bochum2 Regensburg2 Gifhorn1 Schwerin1 Wuppertal1 Bünde1 Goettigen1 Neuruppin1 Elsterwerda1 Fulda1 Homburg1 Dortmund1 Alsfeld1 Bergisch Gladbach1 Brilon1 Bruchsal1 Bernau bei Berlin1 Bad Berka1 Brandenburg1 Buchholz1 Karlsburg1 Magdeburg1 Remscheid1 Bad Segeberg1 Amberg1 Bad Homburg1 Friedrichshafen1 Stuttgart1 Winnenden1 Gera1 Dessau1 Bottrop1 Heide1 Osnabrück1 Gelsenkirchen1 Paderborn1 Stade1
All 77 locations
Target enrolment
to

Heart Failure trials in Germany

69 of 5062 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Not yet open
A Comparison of Left Bundle Branch Optimized Cardiac Resynchronization Therapy vs Left Bundle Branch Area Pacing Alone
NCT07842874Heart Failure, Left Bundle Branch Area Pacing, Cardiac Resynchronization Therapy, Conduction System Pacing
PD Dr. Guram Imnadze
Not applicable
124
Neuruppin
2027-02
Not yet open
Zoll Medical Corporation
Not applicable
800
Giessen
2026-10-01
Recruiting
Edwards Lifesciences
Not applicable
15
Cologne, Dresden, Mainz
2026-10
Recruiting
Intrahospital Influenza Vaccination in Patients at High Cardiovascular Risk (VACC-UP)
NCT07721649Acute Coronary Syndrome, Heart Failure, Influenza, Human, Cardiovascular Diseases
Stephan Baldus
Not applicable
482
Cologne, Hamburg
2026-09-30
Not yet open
University Medical Center Groningen
Not applicable
292
Gelsenkirchen, Mainz, München, Paderborn, Stade
2026-07
Recruiting
Biotronik SE & Co. KG
Observational
151
Würzburg, Gera
2026-06-22
Recruiting
Novo Nordisk A/S
Phase 1
32
Berlin
2026-06-17
Not yet open
Screening, Characterization, and Longitudinal Follow-up of Patients With Cardiac Amyloidosis
NCT07577466Amyloidosis Cardiac, Heart Failure, Cardiac MRI, Spectroscopic Analysis
Heinrich-Heine University, Duesseldorf
Observational
200
Düsseldorf
2026-06-15
Recruiting
Novo Nordisk A/S
Phase 3
5,610
Aachen, Bad Friedrichshall, Bad Oeynhausen, Berlin, Bochum, Coburg, Cologne, Dresden
2026-05-11
Recruiting
Echosens
Not applicable
149
Berlin
2026-04-23
Not yet open
Universitat Internacional de Catalunya
Observational
90
Aachen
2026-03
Recruiting
Pacing Advancements With Cost and Experience VALuation for Unified Patient-Led Clinical Evidence - the PACEVALUE Study
NCT07276139Cardiomyopathy, Secondary, Arrhythmias, Cardiac, Heart Failure, Pacing Induced Cardiomyopathy
Insel Gruppe AG, University Hospital Bern
Observational
4,500
Bad Krozingen
2026-01-01
Recruiting
Herzzentrum Bremen
Not applicable
200
Bremen
2025-10-01
Recruiting
Karlsburg Hospital
Not applicable
30
Karlsburg
2025-10-01
Recruiting
Abiomed Inc.
Observational
200
Heidelberg, Düsseldorf, Dresden, Leipzig, Berlin, Cologne, Essen
2025-09-21
Recruiting
Biotronik SE & Co. KG
Not applicable
300
Munich
2025-08-22
Recruiting
Charite University, Berlin, Germany
Observational
50
Berlin
2025-08-07
Recruiting
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
NCT07217392Bradycardia, Right Ventricular Pacing, Heart Failure, Atrial Fibrillation (AF)
Abbott Medical Devices
Not applicable
200
Bad Nauheim
2025-07-24
Recruiting
Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk Factors
NCT06796582Heart Failure, Coronary Heart Disease (CHD), Atrial Fibrillation (AF), Diabetes Mellitus
Technical University of Munich
Observational
50
München
2025-07-14
Recruiting
Novo Nordisk A/S
Phase 2
200
Berlin, Dresden, Essen, Frankfurt am Main, Halle, Hanover, Heidelberg, Kiel
2025-06-30
Recruiting
Novo Nordisk A/S
Phase 2
200
Berlin, Dresden, Essen, Frankfurt am Main, Halle, Hanover, Heidelberg, Kiel
2025-06-27
Recruiting
Retrospective Natural History Study of RASopathy-associated Cardiomyopathy (RAS-CM)
NCT07344480Hypertrophic Cardiomyopathy (HCM), Heart Failure, RASopathy
Deutsches Herzzentrum Muenchen
Observational
100
München
2025-06-17
Recruiting
Boehringer Ingelheim
Phase 3
4,200
Bad Friedrichshall, Bamberg, Berlin, Bonn, Bünde, Coburg, Dresden, Erfurt
2025-05-20
Recruiting
AstraZeneca
Phase 3
11,300
Aachen, Amberg, Bad Homburg, Bad Oeynhausen, Bamberg, Bechhofen, Berlin, Bochum
2025-03-14
Recruiting
LMU Klinikum
Observational
2,000
Munich
2025-02-01
Recruiting
Cytokinetics
Phase 3
1,800
Heidelberg, München, Würzburg, Hamburg, Erfurt, Jena, Mainz, Bad Nauheim
2024-12-19
Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195Heart Failure, Heart Diseases, Cardiovascular Diseases, Pulmonary Hypertension
Abbott Medical Devices
Not applicable
850
Leipzig, Hanover, Berlin
2024-12-13
Recruiting
Noah Labs
Observational
60
Berlin, Frankfurt
2024-12-12
Active, closed
Non-interventional Study on Guideline Directed Medical Therapy for Patients With Heart Failure (HF) in Germany
NCT06675552Heart Disease, Heart Failure, Cardiovascular Disease, Heart Failure, Systolic
AstraZeneca
Observational
338
Berlin, Erfurt, Gifhorn, Leipzig, Schwerin, Wuppertal
2024-11-15
Recruiting
University Hospital, Geneva
Not applicable
220
Leipzig
2024-10-01
Recruiting
Preventive Catheter Ablation for Ventricular arrhythmiaS in Patients With End-sTage Heart faiLure
NCT06556485Heart Failure, Arrhythmia, Ventricular, Cardiomyopathy Ischemic, Catheter Ablation
Heart and Diabetes Center North-Rhine Westfalia
Not applicable
160
Bad Oeynhausen
2024-09-13
Recruiting
University of Giessen
Not applicable
1,057
Giessen
2024-09-01
Recruiting
Boehringer Ingelheim
Phase 3
6,712
Aachen, Bad Friedrichshall, Berlin, Bonn, Dessau, Dresden, Erfurt, Frankfurt
2024-06-17
Active, closed
Real-world Study on Dapagliflozin Usage in Patients With Heart Failure (HF) in Germany
NCT06336330Heart Diseases, Cardiovascular Diseases, Heart Failure
AstraZeneca
Observational
831
Aachen, Alsfeld, Bamberg, Bechhofen, Bergisch Gladbach, Berlin, Brilon, Bruchsal
2024-04-25
Recruiting
Prediction of Heart-Failure with Machine Learning
NCT06819618Heart Failure with Reduced Ejection Fraction, Heart Failure, Heart Failure，Congestive, Heart Failure Acute
University Medical Center Goettingen
Observational
32
Goettigen
2024-04-01
Active, closed
Novo Nordisk A/S
Phase 3
673
Bremen, Dresden, Elsterwerda, Erfurt, Frankfurt, Freiburg im Breisgau, Fulda, Homburg
2024-04-01
Recruiting
Efficacy of MitraCLip Vs. PASCAL for the TrEAtment of MitraL REgurgiTation in an All-comer Population
NCT06634121Mitral Regurgitation, Valvular Heart Disease, Heart Failure
LMU Klinikum
Not applicable
180
Munich
2024-04-01
Recruiting
Colorado Prevention Center
Phase 3
5,200
Lübeck, Berlin, Jena, Dresden, Giessen, Regensburg
2024-01-17
Recruiting
European Registry of Transcatheter Repair for Tricuspid Regurgitation
NCT06307262Tricuspid Regurgitation, Valvular Heart Disease, Heart Failure
LMU Klinikum
Observational
3,000
Munich
2023-10-23
Recruiting
Hannover Medical School
Not applicable
300
Hanover
2023-06-28
Recruiting
Merck Sharp & Dohme LLC
Phase 2/3
342
Freiburg im Breisgau, Heidelberg, Erlangen, Hanover, Berlin
2023-05-31
Active, closed
Edwards Lifesciences
Not applicable
100
Bad Oeynhausen, Cologne, Dresden, Heidelberg, Mainz
2023-04-01
Recruiting
Alleviant ALLAY-HF Study
NCT05685303Heart Failure
Alleviant Medical, Inc.
Not applicable
700
Hamburg, Lübeck, Magdeburg
2023-01-10
Active, closed
RESPONDER-HF Trial
NCT05425459Heart Failure, Heart Failure, Diastolic
Corvia Medical
Not applicable
750
Bad Krozingen, Bad Nauheim, Berlin, Cologne, Dresden, Düsseldorf, Freiburg im Breisgau, Göttingen
2022-11-17
Active, closed
University Medical Center Groningen
Phase 3
1,750
Berlin, Düsseldorf, Erlangen, Halle, Hamburg, Hanover, Heidelberg, Heilbronn
2022-11-08
Recruiting
Retrospective Prospective Multicentric Clinical Follow up of Patients After Being Treated With TricValve®
NCT05114850Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Insufficiency, Heart Failure
P+F Products + Features GmbH
Observational
450
Freiburg im Breisgau, Friedrichshafen, Heilbronn, Regensburg, Stuttgart, Winnenden
2022-04-20
Recruiting
Mitochondrial Substrate Utilization in the Diabetic Human Heart
NCT05958706Heart Failure, Type2diabetes, Insulin Resistance, Mitochondrial Diseases
Heinrich-Heine University, Duesseldorf
Observational
500
Düsseldorf
2021-12-01
Recruiting
Carmat SAS
Observational
95
Dresden
2021-11-23
Recruiting
Berlin Heart GmbH
Observational
20
Munich
2021-06-01
Active, closed
AMEND-CRT: Mechanical Dyssynchrony as Selection Criterion for CRT
NCT04225520Left Ventricular Dyssynchrony, Heart Failure, Cardiomyopathy, Dilated, Cardiac Remodeling, Ventricular
Universitaire Ziekenhuizen KU Leuven
Not applicable
500
Cologne, Rostock, Würzburg
2020-12-10
Active, closed
Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy
NCT04463641Heart Failure, Cardiac Resynchronization Therapy
MicroPort CRM
Not applicable
92
Hamburg, Heidelberg, Kiel
2020-12-03
Recruiting
Occlutech International AB
Observational
150
Bottrop, Coburg, Cologne, Erfurt, Hamburg, Heide, Jena, Osnabrück
2020-10-28
Active, closed
IHF GmbH - Institut für Herzinfarktforschung
Not applicable
554
Bad Friedrichshall, Bad Nauheim, Bad Oeynhausen, Berlin, Bielefeld, Bonn, Coburg, Dortmund
2020-10-02
Recruiting
The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R)
NCT04848844Congenital Heart Disease, Heart Failure, Transplant; Complication, Failure, Arrythmia
Universitätsklinikum Hamburg-Eppendorf
Observational
2,000
Hamburg
2020-09-02
Recruiting
University Medical Center Goettingen
Phase 1/2
53
Göttingen, Bad Oeynhausen, Lübeck
2020-02-03
Active, closed
Vectorious Medical Technologies Ltd.
Not applicable
45
Frankfurt
2019-01-08
Active, closed
V-Wave Ltd
Not applicable
605
Berlin, Hamburg, Leipzig, München, Remscheid, Rostock
2018-09-19
Active, closed
Biotronik SE & Co. KG
Observational
3,030
Leipzig, Bad Berka, Bad Oeynhausen, Berlin, Brandenburg, Buchholz, Erlangen, Giessen
2018-05-14
Recruiting
BIO-2-HEART: Identification of Biomarkers in T2DM and Heart Failure
NCT03323216Heart Failure, Diabetes Mellitus, Type 2
RWTH Aachen University
Observational
400
Aachen
2018-04-01
Active, closed
EBR Systems, Inc.
Not applicable
300
Bernau, Erlangen, Hamburg
2018-01-17
Active, closed
REDUCE LAP-HF III Corvia Protocol 1701
NCT03191656Heart Failure
Corvia Medical
Observational
500
Bad Nauheim, Bad Oeynhausen, Bad Segeberg, Berlin, Chemnitz, Cologne, Detmold, Dresden
2017-03-12
Recruiting
CVRx, Inc.
Observational
500
Hamburg, Bad Oeynhausen, Berlin, Bernau, Chemnitz, Cologne, Detmold, Dresden
2016-12-13
Recruiting
IMPRoving Cardiovascular RiSk Stratification Using T1 Mapping in General populatION
NCT04444128Myocarditis, Heart Failure, Myocardial Fibrosis, Vascular Inflammation
Johann Wolfgang Goethe University Hospital
Observational
6,000
Frankfurt am Main
2016-11-15
Active, closed
International T1 Multicenter Outcome Study
NCT03749343Heart Failure, Cardiomyopathies, Inflammatory Disease, Coronary Artery Disease
Johann Wolfgang Goethe University Hospital
Observational
8,000
Bad Nauheim, Frankfurt am Main
2016-03-01
Active, closed
Johannes Gutenberg University Mainz
Observational
3,289
Mainz
2013-01
Active, closed
Neural Cardiac Therapy for Heart Failure Study (NECTAR-HF)
NCT01385176Heart Failure, Congestive Heart Failure
Boston Scientific Corporation
Not applicable
118
Bernau bei Berlin, Göttingen, Hamburg, Leipzig
2011-09-21
Recruiting
Anesthesia for Catheter Aortic Valve ImplantATIOn Registry
NCT01390675Heart Failure, Excessive Amount of Blood / Fluid Transfusion, Intraoperative Cardiac Arrest During Cardiac Surgery, Critical Incident
Deutsches Herzzentrum Muenchen
Observational
10,000
Munich
2011-06
Active, closed
University Hospital Freiburg
Observational
110,000
Freiburg im Breisgau
2004-01-01
Recruiting
Medtronic
Observational
20,000
Aachen, Bad Oeynhausen, Bielefeld, Bremen, Cologne, Dresden, Düsseldorf, Essen
1983-01
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 November 2026. https://priyalifescience.com/clinical-trials-germany/condition/heart-failure

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,062 studies in total at the last sync on 10 Nov 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 69 of those studies listing the condition Heart Failure.

How many Heart Failure trials are recruiting in Germany?

46 of the 69 studies on this page are recruiting new participants as of the 10 Nov 2026, 03:18 UTC sync. A further 5 have not yet opened recruitment, 18 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Heart Failure), 69 studies
PhaseStudiesRecruitingShare
Observational302143.5%
Not applicable261437.7%
Phase 38611.6%
Phase 2222.9%
Phase 1111.4%
Phase 1/2111.4%
Phase 2/3111.4%

Most active sponsors

Lead sponsors with the most studies (Heart Failure)
Lead sponsorStudiesRecruiting
Novo Nordisk A/S54
AstraZeneca31
Biotronik SE & Co. KG32
LMU Klinikum33
Abbott Medical Devices22
Boehringer Ingelheim22
Corvia Medical20
Deutsches Herzzentrum Muenchen22
Edwards Lifesciences21
Heinrich-Heine University, Duesseldorf21
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.