MyoVasc Study on the Development and Progression of Heart Failure

NCT04064450 · tracked via the Priya Life Science Germany tracker

Sponsor

Johannes Gutenberg University Mainz

Phase

Observational

Started

2013-01

Last updated

2024-08-22

Condition(s) studied

Heart Failure

Study summary

The MyoVasc - Study is an observational, prospective cohort study. The study is investigating the development and progression of the heart failure syndrome, phenotypes of the heterogeneous syndrome, and the interactions of phenotypes with the vasculature regarding their impact for the course of heart failure.

Eligibility

Sex

ALL

Min age

35 Years

Max age

84 Years

Healthy volunteers

Accepted

Inclusion Criteria: * Asymptomatic heart failure or symptomatic heart failure * Written consent * Sufficient knowledge of the German language, in order to understand study documents and computer assisted interview without any translation Exclusion Criteria: * Individuals who are not able to visit the study center due to psychological or physical impairment * STEMI within the last 4 months, NSTEMI within the last 3 months * Acute decompensated heart failure * Surgery, especially coronary artery bypass grafting within the last 3 months * Acute disease, especially acute infectious disease, endocarditis, myocarditis or pericarditis

Primary outcome measure(s)

Incidence of Worsening of Heart Failure — Assessment in annual follow-up contacts over a period of 10 years
The primary outcome "worsening of heart failure" differs between groups: * Population Controls: i.e. composite of cardiac death and incident heart failure (i.e. incident asymptomatic or symptomatic heart failure) * Individuals with asymptomatic heart failure: i.e. composite of cardiac death and transition from asymptomatic to symptomatic heart failure * Individuals with symptomatic heart failure: i.e. composite of cardiac death and hospitalization due to worsening of heart failure

Trial sites (1)

Facility	City	Region	Status
University Medical Center of the Johannes Gutenberg-University Mainz	Mainz	Rhineland-Palatinate

More Johannes Gutenberg University Mainz trials in Germany

Differential Effects of in Vivo and Virtual Exposure Therapy in Agoraphobia Recruiting

Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness Recruiting

Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years Recruiting

Mainz Intracoronary Database. The Coronary Slow-flow and Microvascular Diseases Registry Recruiting

Study Comparing Two Administration Pathways for Adenosine During Microvascular Function Assessment Starting soon

Other trials for the same condition

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients Recruiting

Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device. Recruiting

Voice Analysis to Detect Pulmonary Arterial Pressure Changes in Heart Failure Recruiting

Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure Recruiting

The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R) Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04064450 on ClinicalTrials.gov ↗ ← All trials in Germany