Impact of Iron Supplementation During Pregnancy

NCT07814378 · tracked via the Priya Life Science Germany tracker

Sponsor

Johann Wolfgang Goethe University Hospital

Phase

Observational

Started

2026-10-01

Last updated

2026-09-11

Condition(s) studied

AnemiaIron Deficiency Anaemia in ChildbirthPregnancy

Investigational drug(s) / intervention(s)

Iron →

Iron: Iron supplementation will be performed according to Hamza et al., Recommendations of the AGG (Obstetrics Working Group, Section for Maternal Diseases) for the Management of Anemia in Pregnancy - Part 1 (Iron Deficiency Anemia) (https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-2628-7308.pdf)

Study summary

During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth. Around half of pregnant women develop anemia, and after delivery, up to 85% of women may be affected.

This study looks at whether iron given through a vein (intravenous iron) can improve blood levels and how women feel and function in everyday life before and after giving birth.

Eligibility

Sex

FEMALE

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Pregnancy Exclusion Criteria: * Thalassemia * Sickle cell disease * Aplastic anemia * Hemochromatosis * Chronic inflammatory diseases associated with anemia of chronic disease * Severe renal insufficiency * Intravenous iron administration within 3 months prior to enrollment

Primary outcome measure(s)

Proportion of patients achieving an increase in hemoglobin concentration of ≥1 g/dL — between iron supplementation and follow-up: 2-4 weeks
Proportion of patients with an increase in hemoglobin concentration of ≥1 g/dL from before the first intravenous iron administration to the last available measurement before delivery

Trial sites (2)

Facility	City	Region	Status
University Hospital Frankfurt, Department for Anaesthesiolgy, Intensive Care, and Pain Therapy	Frankfurt	Germany
University Hospital Würzburg, Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine	Würzburg	Germany

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07814378 on ClinicalTrials.gov ↗ ← All trials in Germany